Cal/Mag 500 mg/250 mg

Cal/Mag 500 mg/250 mg

NaturesPlus4.7 (683 ratings)
Format:Tablet Quantity: 180 Tablet(s) · 180 servings
Goals
$24.69 $0.13 per serving

Product analysis

77 out of 100

Cal/Mag 500 mg/250 mg offers an affordable way to fill calcium and magnesium gaps that matter for bone maintenance and normal energy processes. Benefits are most relevant when dietary intake is low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality63

The magnesium preparation compares more favorably than the calcium preparation for how readily it may be absorbed. The amino acid descriptions do not establish stronger bone outcomes.

Ingredient Transparency100

Both mineral amounts and forms are clearly disclosed. That supports straightforward comparison of the calcium and magnesium contributions.

Value For Money87

The calcium and magnesium combination is economically priced for its mineral content. Both ingredients contribute to its favorable value.

Customer Satisfaction79

Customer feedback is favorable across several hundred ratings. The breadth of feedback offers a useful view of satisfaction without proving health effects.

Product Focus58

Two minerals cover several related nutritional roles, with bone support the clearest practical purpose. The wider stress, hormone and cardiovascular connections are more uncertain.

Format
Tablet
Container
180 Tablet(s)
Per serving
$0.13
Customer rating
4.7 · 683 ratings
Report analysis

Goals

Bone Health
Impact
High effect
B- Ingredient FitD+ PathwaysA+ EvidenceA Formulation Logic
Magnesium · 250 mgCalcium · 500 mg

Calcium supplies mineral for bone formation, and magnesium supports normal bone metabolism when dietary intake is low. The 500 mg calcium serving is a practical amount for filling an intake gap; total needs include food. These amino acid chelates do not establish superior bone outcomes. Fracture findings for calcium are mixed, and magnesium supplementation has not reliably demonstrated routine fracture prevention.

How this product is rated for Bone Health

Ingredient fit75

Calcium and magnesium are the two credited ingredients, with no off-goal actives.
Goal fit
Calcium and magnesium are the two credited ingredients, with no off-goal actives.
Dose adequacy
Both amounts receive partial recognition against the saved anchors; that does not make them ineffective.

Pathways55

Mineral supply is strongest, with a smaller calcium-regulation finding.
Depth
Bone mineral supply is the strongest saved route.
Breadth
Only mineral supply reaches the saved coverage threshold.

Evidence100

Calcium leads the saved evidence finding. Recognized credit does not establish routine fracture prevention.
Evidence strength
Calcium supplies the leading evidence finding; the supplied scientific limitations still apply.
Studied preparation
Both credited mineral preparations are recognized without a chelate superiority claim.

Formulation logic92

Calcium lacks its vitamin D partner and retains a partial standalone contribution. No configured conflict was applied.
Partner coverage
Calcium lacks its vitamin D partner and retains a partial standalone contribution.
Conflicts
No configured conflict was applied; the very-high-vitamin-D condition is not met.
Effective doses
Both credited minerals pass the saved amount threshold.
Study evidence
Calcium Supportive 144 studies
Magnesium Supportive 48 studies
Impact
High effect
B Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Magnesium · 250 mg

Calcium helps fill a dietary gap relevant to bone maintenance, and magnesium provides nutritional support across energy-related processes and mineral metabolism. Both receive partial amount coverage in the saved comparison. This does not imply a need to increase them or establish additional benefit with adequate intake. Amino-acid chelate names receive no assumed superiority, and nutrient amounts are distinct from absorbed doses.

How this product is rated for Everyday Health

Ingredient fit79

Calcium and magnesium are counted, both with partial amount coverage.
Goal fit
The two minerals give the formula a focused nutritional purpose, alongside links to other goals.
Dose adequacy
Both minerals provide partial saved amount coverage without implying that more would improve health.

Pathways50

Magnesium provides energy-related and mineral-metabolism coverage; calcium is tracked under nutrient sufficiency.
Depth
Energy-related nutrient processes have the strongest partial coverage.
Breadth
Only energy-related processes meet the coverage threshold.

Evidence86

Magnesium leads the evidence finding for conditional nutritional support.
Evidence strength
Magnesium supplies the leading evidence contribution without establishing extra benefit above adequate nutrition.
Studied preparation
Both mineral declarations receive full preparation recognition without a chelate advantage.

Formulation logic100

Both minerals satisfy partner requirements and no configured conflict was found.
Partner coverage
Neither mineral lacks a required partner.
Conflicts
No configured ingredient conflict was matched.
Effective doses
Both minerals pass the minimum amount threshold.
Study evidence
Magnesium Supportive 114 studies
Stress Relief
Impact
Moderate effect
C Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Magnesium · 250 mg

Magnesium may help you feel less stressed if your magnesium levels are low. The declared amino acid chelate supplies the mineral, but the form alone doesn’t show a greater calming benefit. Lasting relief from everyday stress is less clear when magnesium intake is already adequate.

How this product is rated for Stress Relief

Ingredient fit64

Magnesium may help with stress when levels are low; lasting everyday relief is uncertain.
Goal fit
Magnesium provides the relevant conditional connection to stress relief.
Dose adequacy
Magnesium: 250 mg per selected serving.

Pathways20

Magnesium relates mainly to calming, with the practical benefit limited by the ingredient’s applicability.
Depth
Magnesium relates mainly to calming, with the practical benefit limited by the ingredient’s applicability.
Breadth
The connection is concentrated in calming rather than broad relief across stress-related processes.

Evidence76

Magnesium may help with stress when levels are low; lasting everyday relief is uncertain.
Evidence strength
Magnesium may help with stress when levels are low; lasting everyday relief is uncertain.
Studied preparation
Magnesium has an identifiable preparation applicable to its relevant ingredient context; this doesn’t guarantee an individual benefit.

Formulation logic100

Magnesium doesn’t depend on an additional partner ingredient. No particular ingredient conflict is identified.
Partner coverage
Magnesium doesn’t require an additional partner ingredient for its described role.
Conflicts
No particular ingredient conflict is identified.
Effective doses
Magnesium: 250 mg per selected serving.
Study evidence
Magnesium Supportive 13 studies
Impact
High effect
C Ingredient FitD- PathwaysA- EvidenceA+ Formulation Logic
Magnesium · 250 mg

Magnesium supports electrolyte balance and blood-vessel tone, although blood-pressure effects are small and inconsistent.

How this product is rated for Heart Health

Ingredient fit64

Magnesium connect to heart-related functions. Some amounts provide only partial exposure relative to the supplied comparisons.
Goal fit
Magnesium provide the relevant connection; the product's broader ingredient and goal mix limits its focus.
Dose adequacy
Magnesium provide partial exposure compared with the supplied comparison ranges; this does not establish an ineffective dose.

Pathways45

The clearest connection is electrolyte and vascular-tone balance. Support is concentrated in that route.
Depth
The strongest represented route is electrolyte and vascular-tone balance, with support limited to the ingredients and amounts supplied.
Breadth
The findings cover one route, with limited breadth beyond that mechanism.

Evidence89

Magnesium supplies the strongest relevant support here, though blood-pressure results are inconsistent.
Evidence strength
Magnesium supplies the strongest relevant support here, though blood-pressure results are inconsistent.
Studied preparation
The eligible declared ingredients meet the supplied preparation comparison; this does not establish superiority over other forms.

Formulation logic100

The relevant ingredients do not require another partner, and no specified conflict was identified. The amount comparisons do not establish added benefit from combining ingredients.
Partner coverage
The relevant ingredients can contribute without an additional required partner; no extra combination benefit is established.
Conflicts
No specified ingredient conflict was identified in the supplied findings.
Effective doses
The ingredients included in this finding clear the supplied minimum exposure comparison; this is not a proven clinical efficacy threshold.
Study evidence
Magnesium Supportive 158 studies
Energy
Impact
Moderate effect
C Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
Magnesium · 250 mg

Magnesium at 250 mg supports normal energy metabolism and helps meet nutritional needs. Correcting a shortfall may help fatigue, but the supplied evidence does not establish additional energy from magnesium when status is adequate.

How this product is rated for Energy

Ingredient fit64

Relevant energy-related ingredients are present alongside ingredients serving other needs. The relevant amounts provide a partial match to the supplied dose comparisons.
Goal fit
Relevant energy-related ingredients are present alongside ingredients serving other needs.
Dose adequacy
The relevant amounts provide a partial match to the supplied dose comparisons.

Pathways0

The saved findings show nutritional support without meaningful coverage of the listed energy mechanisms. The saved findings show limited reach across the different aspects of energy support.
Depth
The saved findings show nutritional support without meaningful coverage of the listed energy mechanisms.
Breadth
The saved findings show limited reach across the different aspects of energy support.

Evidence88

Magnesium provides the strongest relevant evidence at the assessed amount, with benefits dependent on nutritional status or clinical context. The qualifying ingredients match preparations represented in the supplied evidence.
Evidence strength
Magnesium provides the strongest relevant evidence at the assessed amount, with benefits dependent on nutritional status or clinical context.
Studied preparation
The qualifying ingredients match preparations represented in the supplied evidence.

Formulation logic100

The assessed ingredients can contribute on their own or have their required partner present. No ingredient conflicts were identified in the saved assessment. All assessed ingredients met the saved minimum amount criterion.
Partner coverage
The assessed ingredients can contribute on their own or have their required partner present.
Conflicts
No ingredient conflicts were identified in the saved assessment.
Effective doses
All assessed ingredients met the saved minimum amount criterion.
Study evidence
Magnesium Supportive 4 studies
Cardiovascular Support
Impact
High effect
C Ingredient FitD- PathwaysB EvidenceA+ Formulation Logic
Magnesium · 250 mg

Magnesium supports vascular function and may influence arterial stiffness, although trial findings are inconsistent and benefits are more plausible with low magnesium status or elevated blood pressure. The 250 mg per serving provides a partial comparison with the saved amount comparison, without guaranteeing an effect. The supplied evidence does not establish broad cardiovascular-event prevention or superior effects from this magnesium form.

How this product is rated for Cardiovascular Support

Ingredient fit64

Magnesium provides the relevant vascular role within a formula also serving other nutritional goals.
Goal fit
Magnesium is the only reviewed contributor, alongside ingredients serving other goals.
Dose adequacy
The 250 mg magnesium serving provides a partial comparison with study exposure, without implying a measured proportional benefit.

Pathways43

Magnesium accounts for the vascular-tone finding; other cardiovascular pathways are not covered.
Depth
Magnesium provides the strongest saved coverage through vascular tone and sodium balance.
Breadth
Vascular tone is the only pathway reaching the saved coverage threshold.

Evidence79

Magnesium leads the evidence comparison; studies of arterial stiffness and blood pressure have yielded inconsistent results.
Evidence strength
Magnesium leads the evidence comparison; studies of arterial stiffness and blood pressure have yielded inconsistent results.
Studied preparation
Magnesium satisfies the saved preparation check, but no cardiovascular advantage is established for its particular salt or complex.

Formulation logic100

No required partners or ingredient conflicts were flagged, and the counted ingredients passed the amount check.
Partner coverage
The counted ingredients work independently or meet the saved partner requirements.
Conflicts
No ingredient conflicts were identified in the supplied checks.
Effective doses
Magnesium passes the saved minimum amount check; this is not a guarantee of clinical benefit.
Study evidence
Magnesium Supportive 123 studies

Ingredients

IngredientAmount per servingScore
Calcium (Calcium Amino Acid Chelate)
500 mg 80
Magnesium (Magnesium Amino Acid Chelate)
250 mg 72
Gluten Free Adults 18–50 Vegetarian
Report overview
C+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 500 mg of calcium. The listed source is calcium amino acid chelate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability65

The source is identified as calcium amino acid chelate, and the calcium amount is declared separately from compound weight.
Calcium Form & Absorption Potential
The identified calcium source is calcium amino acid chelate.
Elemental Calcium Transparency
The saved facts identify 500 mg as calcium itself per serving, rather than the weight of the source compound.

Dose, Safety & Label Transparency84

Each serving provides 500 mg of calcium. A flow agent is recorded in the ingredient panel.
Absorption-Optimized Serving Dose
Each serving provides 500 mg of calcium.
Formulation Purity & Additives
The evaluated ingredient panel records a flow agent; its identity is not provided in the saved facts.

Value100

A serving costs about $0.14 for the whole product and provides 500 mg of calcium.
Price Per Serving Efficiency
The saved price is about $0.14 per whole-product serving.
D Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB+ Value
A serving supplies 250 mg of magnesium. Its identified source is magnesium amino acid chelate.
How this ingredient is rated

Active Ingredient Quality & Bioavailability49

Magnesium Amino Acid Chelate is the identified magnesium source.
Magnesium Form & Absorption Potential
Magnesium Amino Acid Chelate is the identified magnesium source.
Patented Materials & Chelation Quality
The saved facts do not establish a qualifying branded material or a full-chelation or full-reaction claim.

Dose, Safety & Label Transparency90

A serving supplies 250 mg of magnesium. No positive amount of a qualifying cofactor is recorded in the saved facts.
Elemental Yield Transparency
The elemental magnesium amount is declared as 250 mg per serving.
Therapeutic Dosage Alignment
A serving provides 250 mg of magnesium.
Synergistic Formulation Logic
No positive amount of a qualifying vitamin B6, vitamin D or boron cofactor is recorded in the saved facts.

Value80

The whole-product serving costs about $0.14.
Price Per Elemental Quality
The whole-product serving costs about $0.14.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysis.
    Manoj P; Derwin R; George S · International journal of older people nursing · 2023
    Meta-analysis12,620 participants7 studies pooledBone Health forCalcium
  2. Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial.
    Storm D; Eslin R; Porter ES; Musgrave K; Vereault D; Patton C; Kessenich C; Mohan S; Chen T; Holick MF; Rosen CJ · The Journal of clinical endocrinology and metabolism · 1998
    Randomized trial60 participantsBone Health forCalcium
  3. The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women.
    Prince R; Devine A; Dick I; Criddle A; Kerr D; Kent N; Price R; Randell A · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 1995
    Randomized trial168 participantsBone Health forCalcium
  4. The efficacy of calcium supplementation alone in elderly Thai women over a 2-year period: a randomized controlled trial.
    Rajatanavin R; Chailurkit L; Saetung S; Thakkinstian A; Nimitphong H · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial404 participantsBone Health forCalcium
  5. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial.
    Bonjour JP; Carrie AL; Ferrari S; Clavien H; Slosman D; Theintz G; Rizzoli R · The Journal of clinical investigation · 1997
    Randomized trial149 participantsBone Health forCalcium
  6. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  7. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  8. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  9. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  10. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  11. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  12. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  13. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  14. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  15. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  16. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  17. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  18. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  19. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  20. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledEveryday Health forMagnesium