Lion's Mane Plus

Lion's Mane Plus

Oregon's Wild Harvest4.8 (81 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 20 servings
Goals
$31.16 $1.55 per serving

Product analysis

48 out of 100

Lion’s Mane Plus combines lion’s mane and ginkgo for memory and focus support, though benefits remain uncertain because findings depend on specific preparations.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality23

The mushroom species is named, but its preparation quality is unclear. Ginkgo and the vitamin forms are unnamed, limiting comparisons for absorption and preparation quality.

Ingredient Transparency67

All listed amounts are shown, making the serving quantities easy to check. Most forms are unnamed, so matching the formula to particular preparations remains difficult.

Value For Money37

The serving cost is relatively high for the lion’s mane contribution. Value for the other ingredients remains uncertain without usable comparisons.

Customer Satisfaction73

Customer ratings are very positive, but they come from a small review base. No specific experiences explain how buyers found the supplement in everyday use.

Product Focus65

The formula concentrates on related goals involving memory, attention and mental performance. Ginkgo evidence is mixed and lion’s mane evidence is preliminary, so reliable improvements in focus or work output cannot be assumed.

Format
Capsule
Container
60 Capsule(s)
Per serving
$1.55
Customer rating
4.8 · 81 ratings
Report analysis

Goals

Cognitive Support
Impact
Highest effect
C+ Ingredient FitB PathwaysA+ EvidenceA+ Formulation Logic
Thiamin · 1.2 mgVitamin B6 · 1.2 mgFolate · 64 mcg DFEVitamin D · 10 mcgHericium mushroom · 1000 mg
Study evidence
Folate Supportive 68 studies
Ginkgo Supportive 87 studies
Thiamin Supportive 30 studies
Vitamin B6 Supportive 17 studies
Vitamin D Supportive 118 studies
Mental Focus
Impact
Moderate effect
B+ Ingredient FitD- PathwaysC- EvidenceA+ Formulation Logic
Folate · 64 mcg DFEVitamin B6 · 1.2 mgVitamin D · 10 mcg
Study evidence
Folate Mixed 12 studies
Ginkgo Supportive 28 studies
Productivity Boost
Impact
Moderate effect
A- Ingredient FitF PathwaysD+ EvidenceA+ Formulation Logic
Vitamin B6 · 1.2 mg
Study evidence
Ginkgo Supportive 20 studies
Impact
High effect
B- Ingredient FitB- PathwaysB+ EvidenceA+ Formulation Logic
Folate · 64 mcg DFEVitamin B6 · 1.2 mgVitamin D · 10 mcgThiamin · 1.2 mg
Study evidence
Folate Supportive 90 studies
Ginkgo Supportive 90 studies
Thiamin Supportive 48 studies
Vitamin B6 Supportive 29 studies
Vitamin D Supportive 94 studies

Ingredients

IngredientAmount per servingScore
Vitamin D2
10 mcg
Thiamine
1.2 mg
Riboflavin
1.1 mg
Niacin
1.8 mg
Vitamin B6
1.2 mg
Folate
64 mcg DFE
Pantothenic Acid
2 mg
Lion's Mane (Hericium erinaceus)
1000 mg 36
Ginkgo Leaf Extract, Powder
300 mg
Gluten Free Adults 18–50 Dairy Free Women
Report overview
F Composition And Label DisclosureD+ Composition And Label DisclosureB+ Commercial Price And Usability
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis.
    Wang Z; Zhu W; Xing Y; Jia J; Tang Y · Nutrition reviews · 2022
    Meta-analysis46,175 participants95 studies pooledBrain Health Cognitive Support forFolate
  2. Folate and long-chain polyunsaturated fatty acid supplementation during pregnancy has long-term effects on the attention system of 8.5-y-old offspring: a randomized controlled trial.
    Catena A; Muñoz-Machicao JA; Torres-Espínola FJ; Martínez-Zaldívar C; Diaz-Piedra C; Gil A; Haile G; Györei E; Molloy AM; Decsi T; Koletzko B; Campoy C · The American journal of clinical nutrition · 2016
    Randomized trial136 participantsBrain Health Mental Focus forFolate
  3. Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial.
    Liu Y; Yu Z; Cai Z; Zhao L; Wang Y; Guo Y; Su X; Miao Y; Yi B; Wang Y; Zhang X · The journal of prevention of Alzheimer's disease · 2025
    Randomized trial220 participantsBrain Health forFolate
  4. Circulating folate concentrations and the risk of mild cognitive impairment: A prospective study on the older Chinese population without folic acid fortification.
    Fu J; Liu Q; Zhu Y; Sun C; Duan H; Huang L; Zhou D; Wang Z; Zhao J; Li Z; Ma F; Li W; Liu H; Zhang X; Chen Y; Wang G; Du Y; Huang G · European journal of neurology · 2022
    Cohort study3,974 participantsBrain Health forFolate
  5. Normal-But-Low Serum Folate Levels and the Risks for Cognitive Impairment.
    Jang S; Han JW; Shin J; Kim TH; Kwak KP; Kim K; Kim BJ; Kim SG; Kim JL; Kim TH; Moon SW; Park JY; Park JH; Byun S; Suh SW; Seo J; So Y; Ryu SH; Youn JC; Lee KH; Lee DY; Lee DW; Lee SB; Lee JJ; Lee JR; Jeong H; Jeong HG; Jhoo JH; Han K; Hong JW; Kim KW · Psychiatry investigation · 2020
    Cohort study3,910 participantsBrain Health forFolate
  6. Efficacy and adverse effects of ginkgo biloba for cognitive impairment and dementia: a systematic review and meta-analysis.
    Tan MS; Yu JT; Tan CC; Wang HF; Meng XF; Wang C; Jiang T; Zhu XC; Tan L · Journal of Alzheimer's disease : JAD · 2015
    Meta-analysis2,561 participants9 studies pooledBrain Health forGinkgo
  7. Efficacy of Ginkgo biloba extract EGb 761® in dementia with behavioural and psychological symptoms: A systematic review.
    von Gunten A; Schlaefke S; Überla K · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2017
    Meta-analysis1,628 participants4 studies pooledBrain Health Cognitive Support forGinkgo
  8. Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials.
    Riepe M; Hoerr R; Schlaefke S · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025
    Meta-analysis782 participants4 studies pooledBrain Health Productivity Boost forGinkgo
  9. Ginkgo biloba extract EGb 761® improves cognition and overall condition after ischemic stroke: Results from a pilot randomized trial.
    Cui M; You T; Zhao Y; Liu R; Guan Y; Liu J; Liu X; Wang X; Dong Q · Frontiers in pharmacology · 2023
    Randomized trial201 participantsBrain Health Productivity Boost forGinkgo
  10. Ginkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mg.
    Herrschaft H; Nacu A; Likhachev S; Sholomov I; Hoerr R; Schlaefke S · Journal of psychiatric research · 2012
    Randomized trial410 participantsBrain Health forGinkgo
  11. Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion's Mane Extracts on Cognitive Performance.
    La Monica MB; Raub B; Ziegenfuss EJ; Hartshorn S; Grdic J; Gustat A; Sandrock J; Ziegenfuss TN · Nutrients · 2023
    Randomized trialBrain Health Productivity Boost forHericium mushroom
  12. Improvement of cognitive functions by oral intake of Hericium erinaceus.
    Saitsu Y; Nishide A; Kikushima K; Shimizu K; Ohnuki K · Biomedical research (Tokyo, Japan) · 2020
    Randomized trialBrain Health Cognitive Support forHericium mushroom
  13. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.
    Mori K; Inatomi S; Ouchi K; Azumi Y; Tuchida T · Phytotherapy research : PTR · 2009
    Randomized trial30 participantsBrain Health Cognitive Support forHericium mushroom
  14. A review of the effects of mushrooms on mood and neurocognitive health across the lifespan.
    Cha S; Bell L; Shukitt-Hale B; Williams CM · Neuroscience and biobehavioral reviews · 2024
    Systematic review34 studies pooledBrain Health forHericium mushroom
  15. Acute effects of a standardised extract of Hericium erinaceus (Lion's Mane mushroom) on cognition and mood in healthy younger adults: a double-blind randomised placebo-controlled study.
    Surendran G; Saye J; Binti Mohd Jalil S; Spreadborough J; Duong K; Shatwan IM; Lilley D; Heinrich M; Dodd GF; Surendran S · Frontiers in nutrition · 2025
    Randomized trial18 participantsBrain Health Mental Focus forHericium mushroom
  16. Can thiamine substitution restore cognitive function in alcohol use disorder?
    Listabarth S; Vyssoki B; Marculescu R; Gleiss A; Groemer M; Trojer A; Harrer C; Weber S; König D · Alcohol and alcoholism (Oxford, Oxfordshire) · 2023
    Clinical trial50 participantsBrain Health forThiamin
  17. EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy.
    Galvin R; Bråthen G; Ivashynka A; Hillbom M; Tanasescu R; Leone MA; EFNS · European journal of neurology · 2011
    Guideline / consensusBrain Health forThiamin
  18. Diagnosis and treatment of Wernicke's encephalopathy: A systematic literature review.
    Cantu-Weinstein A; Branning R; Alamir M; Weleff J; Do M; Nero N; Anand A · General hospital psychiatry · 2024
    Systematic review688 participants27 studies pooledBrain Health forThiamin
  19. Vitamin Supplementation and Dementia: A Systematic Review.
    Gil Martínez V; Avedillo Salas A; Santander Ballestín S · Nutrients · 2022
    Systematic reviewBrain Health forThiamin
  20. Association between dietary vitamin B1 intake and cognitive function among older adults: a cross-sectional study.
    Jia W; Wang H; Li C; Shi J; Yong F; Jia H · Journal of translational medicine · 2024
    Cross-sectional study2,422 participantsBrain Health Cognitive Support forThiamin