MediBolic

MediBolic

Thorne4.5 (33 ratings)
Format:Powder Quantity: 25 Ounce(s) · 14 servings
Goals
$65.95 $4.71 per serving

Product analysis

43 out of 100

MediBolic supplies nutrients that support normal muscle, nerve and skin function, especially when intake is low. Its broad mix and undisclosed blend components make it harder to judge what each extra ingredient adds.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality35

Several nutrient preparations are named, but their relative quality remains uncertain. Other preparations and mixed-source balances are unspecified, limiting comparison of the whole formula.

Ingredient Transparency68

The ingredient amounts and many preparations are stated. Unspecified forms and incomplete source balances, including a proprietary blend, leave parts of the composition unclear.

Value For Money38

The glycine, isoleucine and resveratrol comparisons indicate relatively high cost. Many other ingredients cannot be judged reliably for value, leaving the complete formula difficult to compare.

Customer Satisfaction66

The small set of customer reviews is generally positive. The limited review count gives a narrow view of satisfaction and does not establish health benefits.

Product Focus10

The nutrients have useful roles in maintaining normal function when intake is inadequate. The very broad formula and undisclosed blend make a specific longevity benefit difficult to judge.

Format
Powder
Container
25 Ounce(s)
Per serving
$4.71
Customer rating
4.5 · 33 ratings
Report analysis

Goals

Impact
High effect
C- Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Folate · 500 mcg DFEMagnesium · 150 mgVitamin B12 · 100 mcgVitamin K · 100 mcgVitamin D · 25 mcgGreen Tea · 200 mgGlycine · 500 mg
Study evidence
Boron Not classified

No linked studies yet.

Folate Supportive 16 studies
Glycine Mixed 14 studies
Green Tea Supportive 9 studies
Magnesium Supportive 12 studies
Selenium Supportive 27 studies
Vitamin C Supportive 30 studies
Vitamin D Supportive 50 studies
Vitamin E Supportive 19 studies
Vitamin K Supportive 27 studies
Zinc Supportive 10 studies

Ingredients

IngredientAmount per servingScore
Calories
140 Calorie(s)
Total Fat
8 Gram(s)
Total Carbohydrates
16 Gram(s)
Protein
18 Gram(s)
Vitamin A
2250 mcg
Vitamin C (Ascorbic Acid)
500 mg
Vitamin D (Vitamin D3)
25 mcg
Vitamin E (D-Alpha-Tocopherol)
134 mg
Vitamin K (Vitamin K1)
100 mcg
Thiamine (Thiamine Hydrochloride)
50 mg
Riboflavin (Riboflavin 5'-Phosphate Sodium)
4 mg
Niacin
40 mg
Vitamin B6 (Pyridoxal 5-Phosphate)
5 mg
Folate
500 mcg DFE
Vitamin B12 (Methylcobalamin)
100 mcg
Biotin
500 mcg
Pantothenic Acid (Calcium Pantothenate)
46 mg
Choline (Choline Citrate)
11 mg
Calcium (Calcium Citrate, DimaCal Dicalcium Malate)
150 mg
Magnesium (Albion DiMagnesium Malate, Magnesium Citrate)
150 mg
Zinc (TRAACS Zinc Bisglycinate Chelate)
10 mg
Selenium (L-Selenomethionine)
75 mcg
Copper (TRAACS Copper Bisglycinate Chelate)
500 mcg
Manganese (TRAACS Manganese Bisglycinate Chelate)
5 mg
Chromium (TRAACS Chromium Nicotinate Glycinate Chelate)
400 mcg
Potassium (Potassium Citrate)
100 mg
Proprietary Blend
22.8 Gram(s)
partially hydrolyzed Guar Gum
10 Gram(s)
Betaine Anhydrous (Trimethylglycine)
1 Gram(s)
Jambolan extract
750 mg
Glycine
500 mg 26
L-Isoleucine
300 mg 52
Cinnamon bark extract
250 mg
Green Tea Phytosome (Camellia sinensis extract, Phospholipid complex)
200 mg 8
Trans-Resveratrol
50 mg 73
Boron (Bororganic Boron Glycinate Complex)
100 mcg
Gluten Free Adults 18–50
Report overview
Glycine · 500 mg OverallScore26
F Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value
A serving provides 500 mg of glycine. The cost per gram of glycine is high. The available details do not establish a glycine grade or purity certification.
How this ingredient is rated

Active Ingredient Quality & Bioavailability0

The available details do not establish a glycine grade or purity certification.
Glycine Sourcing and Purity Standards
The available details do not establish a glycine grade or purity certification.

Dose, Safety & Label Transparency50

The glycine amount is stated as 500 mg per serving. The available details do not establish the other-ingredient findings.
Clinically Relevant Dosage
The serving provides 500 mg of glycine.
Label Transparency and Yield Disclosure
The glycine amount is stated as 500 mg per serving.
Clean Label and Excipient Quality
The available details do not establish the other-ingredient findings.

Value30

The cost per gram of glycine is high.
Cost Efficiency per 1,000mg of Glycine
The cost per gram of glycine is high.
Isoleucine · 300 mg OverallScore52
A- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value
A serving provides 300 mg of isoleucine at a high cost per serving, though the amount is relatively small. It uses L-Isoleucine; the source or manufacturing method is unspecified. No third-party or sport testing is mentioned in the available information.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

It uses L-Isoleucine, an isolated form that is readily available without protein digestion. The source or manufacturing method is not specified.
Free-Form vs. Protein-Bound
It uses L-Isoleucine, an isolated form that is readily available without protein digestion.
Sourcing and Purity Signals
The source or manufacturing method is not specified.

Dose, Safety & Label Transparency35

The label states 300 mg of isoleucine per serving, a relatively small amount. No third-party or sport testing is mentioned in the available information.
Isoleucine Potency per Serving
Each serving provides 300 mg of isoleucine, a relatively small amount.
Label Transparency & Blend Disclosure
The individual isoleucine amount is stated.
Third-Party Safety & Sport Testing
No third-party or sport testing is mentioned in the available information.

Value20

The cost per serving is high.
Price per Serving Efficiency
The cost per serving is high.
Resveratrol · 50 mg OverallScore73
B Composition And Label DisclosureA+ Composition And Label DisclosureF Commercial Price And Usability
The serving provides 50 mg of trans-resveratrol, but the whole-product cost is high for that amount. The available information does not specify the source or trans-resveratrol concentration.
How this ingredient is rated

Composition and Label Disclosure77

Trans-resveratrol is named, but its source and concentration are unclear.
Explicit Label Detail
The ingredient is named as trans-resveratrol.
Trans-Resveratrol Concentration Disclosure
The available information does not state a trans-resveratrol concentration.

Composition and Label Disclosure100

The amount of trans-resveratrol is stated as 50 mg per serving.
Resveratrol Amount Disclosure
The serving contains a stated 50 mg of trans-resveratrol.

Commercial Price and Usability10

The whole-product price is high relative to the declared trans-resveratrol amount.
Cost per 250 mg Declared Trans-Resveratrol
The whole-product price is high relative to the declared trans-resveratrol amount.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. One-carbon metabolism-related compounds are associated with epigenetic aging biomarkers: results from the cross-sectional National Health and Nutrition Examination Survey 1999-2002.
    Bozack AK; Khodasevich D; Nwanaji-Enwerem JC; Gladish N; Shen H; Daredia S; Gamble M; Needham BL; Rehkopf DH; Cardenas A · The American journal of clinical nutrition · 2025
    Cross-sectional study2,346 participantsLongevity forFolate
  2. Longitudinal associations of one-carbon metabolism biomarkers with biological and epigenetic aging in older adults in India.
    Wang J; Crimmins E; Kim JK; Chang NS; Dey S; Lee J; Thyagarajan B; Vivek S · GeroScience · 2026
    Cohort studyLongevity forFolate
  3. Associations between leukocyte telomere length and three measures of folate status: a cross-sectional analysis of NHANES 1999-2002.
    Xue Q; Chen H · Frontiers in nutrition · 2026
    Cross-sectional study7,324 participantsLongevity forFolate
  4. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging.
    Kado DM; Karlamangla AS; Huang MH; Troen A; Rowe JW; Selhub J; Seeman TE · The American journal of medicine · 2005
    Cohort study499 participantsLongevity forFolate
  5. Blood folate is associated with asymptomatic or partially symptomatic Alzheimer's disease in the Nun study.
    Wang H; Odegaard A; Thyagarajan B; Hayes J; Cruz KS; Derosiers MF; Tyas SL; Gross MD · Journal of Alzheimer's disease : JAD · 2012
    Cohort study60 participantsLongevity forFolate
  6. Accelerated biological aging, mediating amino acids, and risk of incident type 2 diabetes: a prospective cohort study.
    Zhang Z; Wang J; Yu B; Sun Y; Chen Y; Lu Y; Wang N; Xia F · Journal of endocrinological investigation · 2025
    Cohort study95,773 participantsLongevity forGlycine
  7. Dietary protein and amino acid intakes for mitigating sarcopenia in humans.
    He W; Connolly ED; Cross HR; Wu G · Critical reviews in food science and nutrition · 2025
    Narrative reviewLongevity forGlycine
  8. Age-Related Neurochemical Changes in the Vestibular Nuclei.
    Smith PF · Frontiers in neurology · 2016
    Narrative reviewLongevity forGlycine
  9. SHMT2 regulates CD8+ T cell senescence via the reactive oxygen species axis in HIV-1 infected patients on antiretroviral therapy.
    Zhang QS; Wang JN; Yang TL; Li SY; Li JQ; Liu DN; Shang H; Zhang ZN · EBioMedicine · 2025
    Observational studyLongevity forGlycine
  10. Metabolomics and incident dementia in older Chinese adults: The Shanghai Aging Study.
    Cui M; Jiang Y; Zhao Q; Zhu Z; Liang X; Zhang K; Wu W; Dong Q; An Y; Tang H; Ding D; Chen X · Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Cohort studyLongevity forGlycine
  11. Green tea and coffee intake and risk of cognitive decline in older adults: the National Institute for Longevity Sciences, Longitudinal Study of Aging.
    Shirai Y; Kuriki K; Otsuka R; Kato Y; Nishita Y; Tange C; Tomida M; Imai T; Ando F; Shimokata H · Public health nutrition · 2021
    Cohort study1,305 participantsLongevity forGreen Tea
  12. Associations of green tea, coffee, and soft drink consumption with longitudinal changes in leukocyte telomere length.
    Sohn I; Shin C; Baik I · Scientific reports · 2023
    Cohort study1,952 participantsLongevity forGreen Tea
  13. Can teatime increase one's lifetime?
    Nakachi K; Eguchi H; Imai K · Ageing research reviews · 2003
    Cohort studyLongevity forGreen Tea
  14. Influences of tea consumption on self-rated health and life satisfaction among older adults: Evidence from the CLHLS.
    Zou M; Sun C; Yang M; Li C; Wang S; Zheng D; Wang J; Yu L; Sun L; Wang Y; Chen H; Zeng Y · PsyCh journal · 2025
    Cohort study78,345 participantsLongevity forGreen Tea
  15. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin.
    Chiu AE; Chan JL; Kern DG; Kohler S; Rehmus WE; Kimball AB · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial40 participantsLongevity forGreen Tea
  16. Dietary Magnesium May Be Protective for Aging of Bone and Skeletal Muscle in Middle and Younger Older Age Men and Women: Cross-Sectional Findings from the UK Biobank Cohort.
    Welch AA; Skinner J; Hickson M · Nutrients · 2018
    Cross-sectional study156,575 participantsLongevity forMagnesium
  17. Higher Magnesium Intake Is Associated with a Lower Risk of Frailty in Older Adults.
    Dominguez LJ; Mérida DM; Donat-Vargas C; Banegas JR; Veronese N; Barbagallo M; Rodríguez-Artalejo F; Guallar-Castillón P · Journal of the American Medical Directors Association · 2024
    Cohort study1,900 participantsLongevity forMagnesium
  18. Ca:Mg Ratio, APOE Cytosine Modifications, and Cognitive Function: Results from a Randomized Trial.
    Zhu X; Borenstein AR; Zheng Y; Zhang W; Seidner DL; Ness R; Murff HJ; Li B; Shrubsole MJ; Yu C; Hou L; Dai Q · Journal of Alzheimer's disease : JAD · 2021
    Randomized trial250 participantsLongevity forMagnesium
  19. The Association between Dietary Nutrient Intake and Acceleration of Aging: Evidence from NHANES.
    Ma J; Li P; Jiang Y; Yang X; Luo Y; Tao L; Guo X; Gao B · Nutrients · 2024
    Cross-sectional study4,692 participantsLongevity forMagnesium Longevity forZinc
  20. Interpretable machine learning with SHAP analysis identifies redox-modulating dietary antioxidants for predicting accelerated biological aging.
    Zhang B; Zhang X; Ma L; Li D; Li Y; Lin S; Peng L; He L · Experimental gerontology · 2026
    Cross-sectional study8,125 participantsLongevity forMagnesium