Vitamin K2 100 mcg + Vitamin D3 125 mcg

Vitamin K2 100 mcg + Vitamin D3 125 mcg

Nutricost4.8 (5,590 ratings)
Format:Softgel Quantity: 120 Softgel(s) · 120 servings
Goals
$14.95 $0.12 per serving

Product analysis

78 out of 100

Vitamin K2 100 mcg + Vitamin D3 125 mcg pairs nutrients that support bone health, particularly when vitamin D levels are low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality66

Vitamin K is supplied as MK-7, a favorable form for the intended bone-related use. Vitamin D3 is named, but its comparative form quality cannot be established from the available information.

Ingredient Transparency100

Both vitamin amounts and forms are stated clearly. You can compare the serving directly with other vitamin D and K combinations.

Value For Money66

The MK-7 contribution offers favorable value at the serving cost. Value for the vitamin D contribution remains uncertain without a usable comparison.

Customer Satisfaction91

Customer ratings are very positive across a large review base. That provides a broad picture of satisfaction, without proving the claimed health benefits.

Product Focus76

The two vitamins have related roles in bone and mineral health, without an established extra benefit from combining them. The 125 mcg vitamin D serving exceeds the nutritional reference, so the large amount should not be assumed to bring extra benefit or establish safety.

Format
Softgel
Container
120 Softgel(s)
Per serving
$0.12
Customer rating
4.8 · 5,590 ratings
Report analysis

Goals

Everyday Health
Impact
Highest effect
B+ Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Vitamin D · 125 mcgVitamin K · 100 mcg
Study evidence
Vitamin D Supportive 115 studies
Vitamin K Supportive 34 studies
Longevity
Impact
High effect
A- Ingredient FitF PathwaysB- EvidenceA+ Formulation Logic
Vitamin K · 100 mcgVitamin D · 125 mcg
Study evidence
Vitamin D Supportive 50 studies
Vitamin K Supportive 27 studies
Heart Health
Impact
High effect
B Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Vitamin K · 100 mcgVitamin D · 125 mcg
Study evidence
Vitamin D Mixed 164 studies
Vitamin K Mixed 62 studies
Bone Health
Impact
Highest effect
B+ Ingredient FitB+ PathwaysA+ EvidenceA Formulation Logic
Vitamin K · 100 mcgVitamin D · 125 mcg
Study evidence
Vitamin D Supportive 202 studies
Vitamin K Supportive 78 studies
Cardiovascular Support
Impact
High effect
B Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic
Vitamin K · 100 mcgVitamin D · 125 mcg
Study evidence
Vitamin D Mixed 170 studies
Vitamin K Supportive 40 studies

Ingredients

IngredientAmount per servingScore
Vitamin D (Cholecalciferol)
125 mcg
Vitamin K (Menaquinone-7)
100 mcg 93
Gluten Free Adults 18–50 Vegetarian
Report overview
B+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
Each serving provides 100 mcg of vitamin K at a low cost per serving. It uses vitamin K2 as menaquinone-7 (MK-7). The MK-7 isomer is not specified as trans or all-trans.
How this ingredient is rated

Active Ingredient Quality & Bioavailability82

It uses vitamin K2 as menaquinone-7 (MK-7). The MK-7 isomer is not specified as trans or all-trans.
Vitamin K Form (MK-7 vs. MK-4 vs. K1)
It uses vitamin K2 as menaquinone-7 (MK-7).
MK-7 Isomer Disclosure
The MK-7 isomer is not specified as trans or all-trans.

Dose, Safety & Label Transparency100

It provides 100 mcg of MK-7 per serving. The amount and named form are stated.
Vitamin K2 (MK-7) Dosage Efficacy
It provides 100 mcg of MK-7 per serving.
Form and Subtype Transparency
The amount and named form are stated.

Value100

The cost per serving is low.
Price per Effective MK-7 Serving
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial.
    Moon RJ; D' Angelo S; Curtis EM; Ward KA; Crozier SR; Schoenmakers I; Javaid MK; Bishop NJ; Godfrey KM; Cooper C; Harvey NC; MAVIDOS Trial Group · The American journal of clinical nutrition · 2024
    Randomized trial454 participantsBone Health forVitamin D
  2. Vitamin D analogs and bone: preclinical and clinical studies with eldecalcitol.
    Matsumoto T; Takano T; Saito H; Takahashi F · BoneKEy reports · 2014
    Narrative reviewBone Health forVitamin D
  3. Efficacy of vitamin D fortified foods on bone mineral density and serum bone biomarkers: A systematic review and meta-analysis of interventional studies.
    Tangestani H; Djafarian K; Emamat H; Arabzadegan N; Shab-Bidar S · Critical reviews in food science and nutrition · 2020
    Meta-analysis1,786 participants20 studies pooledBone Health forVitamin D
  4. Cholecalciferol Supplementation Attenuates Bone Loss in Incident Kidney Transplant Recipients: A Prespecified Secondary Endpoint Analysis of a Randomized Controlled Trial.
    Tsujita M; Doi Y; Obi Y; Hamano T; Tomosugi T; Futamura K; Okada M; Hiramitsu T; Goto N; Isaka Y; Takeda A; Narumi S; Watarai Y · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Randomized trial193 participantsBone Health forVitamin D
  5. Vitamin D supplementation and bone health in post-menopausal women: a 24-month randomized controlled intervention with enhanced bioavailability formulations.
    Rasool N; Munir Y · European journal of clinical nutrition · 2026
    Randomized trial612 participantsBone Health forVitamin D
  6. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials.
    Cockayne S; Adamson J; Lanham-New S; Shearer MJ; Gilbody S; Torgerson DJ · Archives of internal medicine · 2006
    Meta-analysis13 studies pooledBone Health forVitamin K
  7. Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
    Knapen MH; Drummen NE; Smit E; Vermeer C; Theuwissen E · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Randomized trial244 participantsBone Health forVitamin K
  8. Effect of combined administration of vitamin D3 and vitamin K2 on bone mineral density of the lumbar spine in postmenopausal women with osteoporosis.
    Iwamoto J; Takeda T; Ichimura S · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2001
    Randomized trial92 participantsBone Health forVitamin K
  9. Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review.
    Zhou M; Han S; Zhang W; Wu D · Journal of bone and mineral metabolism · 2022
    Meta-analysis6,853 participants9 studies pooledBone Health forVitamin K
  10. Low-dose vitamin K2 (MK-4) supplementation for 12 months improves bone metabolism and prevents forearm bone loss in postmenopausal Japanese women.
    Koitaya N; Sekiguchi M; Tousen Y; Nishide Y; Morita A; Yamauchi J; Gando Y; Miyachi M; Aoki M; Komatsu M; Watanabe F; Morishita K; Ishimi Y · Journal of bone and mineral metabolism · 2015
    Randomized trial48 participantsBone Health forVitamin K
  11. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forVitamin D
  12. A Randomized Trial of Vitamin D Supplementation on Vascular Function in CKD.
    Kumar V; Yadav AK; Lal A; Kumar V; Singhal M; Billot L; Gupta KL; Banerjee D; Jha V · Journal of the American Society of Nephrology : JASN · 2017
    Randomized trial120 participantsCardiovascular Support forVitamin D
  13. Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.
    Porto C; Petribu K; Barbosa N; Magalhães R; Lira C; Porto AB; Markman-Filho B; Lordsleem A; Calado E; Magalhães J; Sougey E; Silva T; Junio A; Bandeira F; Leão R · American heart journal plus : cardiology research and practice · 2025
    Randomized trial224 participantsCardiovascular Support forVitamin D
  14. Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial.
    Raed A; Bhagatwala J; Zhu H; Pollock NK; Parikh SJ; Huang Y; Havens R; Kotak I; Guo DH; Dong Y · PloS one · 2017
    Randomized trial70 participantsCardiovascular Support forVitamin D
  15. Paricalcitol and endothelial function in chronic kidney disease trial.
    Zoccali C; Curatola G; Panuccio V; Tripepi R; Pizzini P; Versace M; Bolignano D; Cutrupi S; Politi R; Tripepi G; Ghiadoni L; Thadhani R; Mallamaci F · Hypertension (Dallas, Tex. : 1979) · 2015
    Randomized trial88 participantsCardiovascular Support Heart Health forVitamin D
  16. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsCardiovascular Support Heart Health forVitamin K
  17. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsCardiovascular Support Heart Health forVitamin K
  18. Effects of One-Year Menaquinone-7 Supplementation on Vascular Stiffness and Blood Pressure in Post-Menopausal Women.
    de Vries F; Bittner R; Maresz K; Machuron F; Gåserød O; Jeanne JF; Schurgers LJ · Nutrients · 2025
    Randomized trial165 participantsCardiovascular Support forVitamin K
  19. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsCardiovascular Support Heart Health forVitamin K
  20. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsCardiovascular Support Heart Health forVitamin K