$8.31 $0.13 per serving
Product analysis
5-HTP 100 mg may help some people with poor sleep and may support fullness, though the evidence is limited.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality40
The Griffonia seed extract identifies the source of 5-HTP. Its form quality cannot be judged confidently from the available detail.
Ingredient Transparency100
The 5-HTP amount and plant source are disclosed. That makes the main ingredient straightforward to identify and compare.
Value For Money100
The 5-HTP amount offers strong value for the serving cost. The cost advantage is clearest for someone seeking 5-HTP alone.
Customer Satisfaction91
Customer ratings are strongly positive across a very large body of feedback. The volume gives a broad picture of satisfaction, although reviews do not show whether a health benefit occurs.
Product Focus66
The single-ingredient formula focuses on 5-HTP and its possible sleep and appetite roles. Reliable everyday improvements in mood or stress remain uncertain.
- Format
Capsule - Container
- 60 Capsule(s)
- Per serving
- $0.13
- Also available
5-HTP 50 mg$6.10- Customer rating
- 4.7 · 53,050 ratings
Goals
Impact
Highest effect
5-HTP · 100 mg
5-HTP is a building block for serotonin, a messenger involved in mood. The supplied findings do not establish a mood improvement over a control in generally healthy adults, despite its clear biochemical role. The declared amount is fully recognized in the saved amount comparison, but that does not establish a reliable everyday emotional benefit.
How this product is rated for Mood Support
Ingredient fit95
The declared amounts fully meet the saved comparison references; this does not establish an effective dose for every user.
Goal fit
The relevant ingredients dominate the formula, although its wider uses also influence how specifically it addresses mood.
Dose adequacy
The declared amounts fully meet the saved comparison references; this does not establish an effective dose for every user.
Pathways59
The main recognized connection is monoamine signalling. This describes the supplied ingredient roles, without proving a mood effect.
Depth
The main recognized connection is monoamine signalling. This describes the supplied ingredient roles, without proving a mood effect.
Breadth
One route reaches the saved coverage reference, so the recognized connections to mood remain concentrated.
Evidence94
5-HTP provides the leading recognized evidence contribution; its population and outcome limitations still govern what emotional benefit can be expected.
Evidence strength
5-HTP provides the leading recognized evidence contribution; its population and outcome limitations still govern what emotional benefit can be expected.
Studied preparation
The qualifying ingredients are recognized as matching the saved preparation criteria; that does not make all preparations or populations interchangeable.
Formulation logic100
The recognized ingredients meet the partner requirements, and no evaluated ingredient conflict is triggered.
Partner coverage
The recognized ingredients do not depend on a missing partner under the supplied findings.
Conflicts
None of the evaluated ingredient combinations triggers a listed conflict; this finding does not establish medication compatibility.
Effective doses
All ingredients retained for this comparison meet its minimum amount threshold; this is not proof of clinical effectiveness.
Impact
Moderate effect
5-HTP may support sleep quality for people with poor sleep, though the possibility is not established for everyone. With 100 mg as its only sleep-related ingredient, this product offers one narrow potential route.
The amount matches the sleep-quality amount most closely tied to this possible role for 5-HTP, but that does not establish general improvement for all adults. It does not separately address sleep timing, onset, or relaxation.
How this product is rated for Sleep Support
Ingredient fit95
The formula relies on a single ingredient for possible sleep-quality support, without a second ingredient for another part of sleep.
Goal fit
5-HTP is the sole sleep-related active, keeping the product focused on one possible route.
Dose adequacy
The label provides 100 mg of 5-HTP, the amount most closely associated with its possible sleep-quality role.
Pathways60
5-HTP is related to serotonin and melatonin production, but the product does not separately address sleep timing or calming.
Depth
The route related to serotonin and melatonin is the only represented sleep pathway in this single-ingredient product.
Breadth
The product covers a route related to serotonin and melatonin, without separate timing, calming, or stress-related support.
Evidence58
The possible 5-HTP sleep-quality role is more limited and context-specific than melatonin’s.
Evidence strength
The possible sleep-quality benefit from 5-HTP is limited to a narrower context, especially poor sleepers.
Studied preparation
The label names active 5-HTP directly, so no extract identity is needed to understand what is present.
Formulation logic100
5-HTP is considered on its own, with no conflicting ingredient combination identified.
Partner coverage
5-HTP’s possible role does not depend on a companion ingredient.
Conflicts
No conflicting ingredient combination is identified.
Effective doses
The 100 mg amount gives 5-HTP a substantial role here, while its context-specific sleep potential remains uncertain.
Impact
Moderate effect
5-HTP may help with anxiety or stress in some circumstances, but how well that translates to everyday stress remains unclear. Its connection is mainly with mood and the production of chemical messengers in the nervous system. The declared amount is known; that helps describe what you're taking, but it doesn't make the benefit predictable for day-to-day pressures.
How this product is rated for Stress Relief
Ingredient fit95
5-HTP: 100 mg. These are serving amounts compared with ingredient-specific daily references, not a daily regimen.
Goal fit
5-HTP is the sole declared active ingredient and has a conditional connection with stress.
Dose adequacy
5-HTP: 100 mg. These are serving amounts compared with ingredient-specific daily references, not a daily regimen.
Pathways46
The ingredient connections center on mood and the production of chemical messengers. They don't describe how likely you are to feel relief.
Depth
The strongest connection concerns mood and the production of chemical messengers; this describes the ingredient roles rather than a promised symptom change.
Breadth
The connection is concentrated mainly on mood and the production of chemical messengers, with less breadth across other stress-related processes.
Evidence56
5-HTP has a possible anxiety and stress benefit, with uncertain everyday applicability.
Evidence strength
5-HTP has a possible anxiety and stress benefit, with uncertain everyday applicability.
Studied preparation
The 5-HTP ingredient and amount are identified; no special preparation distinction applies here.
Formulation logic100
No particular conflict or missing required partner is identified among the relevant ingredients.
Partner coverage
No required ingredient partner is missing for the ingredients relevant here.
Conflicts
No particular ingredient conflict is identified in this combination.
Effective doses
5-HTP: 100 mg. These are serving amounts compared with ingredient-specific daily references, not a daily regimen.
Impact
Moderate effect
100 mg of 5-HTP relates mainly to appetite and fullness. Small trials suggest it may help reduce food intake, but the limited evidence leaves sustained weight-loss benefits uncertain.
How this product is rated for Weight Loss
Ingredient fit75
5-HTP gives the ingredient selection a clear appetite-related focus. 100 mg of 5-HTP provides partial amount support.
Goal fit
5-HTP gives the ingredient selection a clear appetite-related focus.
Dose adequacy
100 mg of 5-HTP provides partial amount support.
Pathways9
Appetite and fullness are the main connection, with limited overall depth. No pathway reaches the saved threshold for substantial coverage.
Depth
Appetite and fullness are the main connection, with limited overall depth.
Breadth
No pathway reaches the saved threshold for substantial coverage.
Evidence62
5-HTP provides the strongest evidence contribution in the saved findings, with small and limited appetite trials. The saved findings recognize the preparations of the reviewed contributors at qualifying amounts.
Evidence strength
5-HTP provides the strongest evidence contribution in the saved findings, with small and limited appetite trials.
Studied preparation
The saved findings recognize the preparations of the reviewed contributors at qualifying amounts.
Formulation logic100
No configured ingredient conflict was matched in the saved findings. All reviewed contributors meet the saved minimum amount threshold; that threshold is not a guarantee of weight loss.
Partner coverage
The reviewed contributors have no unmet partner requirement in the saved findings.
Conflicts
No configured ingredient conflict was matched in the saved findings.
Effective doses
All reviewed contributors meet the saved minimum amount threshold; that threshold is not a guarantee of weight loss.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
5-HTP (Griffonia simplicifolia Seed Extract) | 100 mg |
5-HTP (Griffonia simplicifolia Seed Extract) · 100 mg OverallScore88
Each serving provides 100 mg of 5-HTP from Griffonia simplicifolia. The label warns about interactions with serotonin-modulating medications.
How this ingredient is rated
Active Ingredient Quality & Bioavailability70
The saved facts identify Griffonia simplicifolia as the source, without a specified 5-HTP standardization percentage.
Botanical Source & Standardization
The saved facts identify Griffonia simplicifolia as the source, without a specified 5-HTP standardization percentage.
Dose, Safety & Label Transparency100
A serving provides 100 mg of 5-HTP. The label warns about interactions with serotonin-modulating medications.
Dosage Potency & Range
A serving provides 100 mg of 5-HTP.
Safety Warnings & Label Clarity
The label warns about interactions with serotonin-modulating medications.
Value100
Based on the whole-product price, 100 mg of 5-HTP corresponds to about $0.14.
Price per 100mg 5-HTP
Based on the whole-product price, 100 mg of 5-HTP corresponds to about $0.14.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
- Tryptophan and 5-hydroxytryptophan for depression.
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
- Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
- Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
- Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
- An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress.
- The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT.
- Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients.
- The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects.
- Serotonergic drugs : effects on appetite expression and use for the treatment of obesity.
- Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan.