GABAplex

GABAplex

Swanson4.7 (191 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$16.19 $0.26 per serving

Product analysis

49 out of 100

GABAplex may help with calming during stressful situations and winding down before sleep. Its glycine and tyrosine are relatively expensive for the amounts supplied.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

Ingredient forms are omitted throughout the formula, making their quality harder to judge. The ingredient names alone do not establish the characteristics of the preparations used.

Ingredient Transparency63

Amounts are disclosed for each ingredient, which helps compare servings. Their forms are omitted, leaving the ingredient descriptions less complete.

Value For Money44

GABA offers reasonably favorable value, but the amounts of glycine and tyrosine are expensive for the cost. Theanine is more middling, giving the mixture an uneven value picture.

Customer Satisfaction73

Customer ratings are very positive, with a modest amount of feedback. The smaller review base makes the satisfaction picture less settled than for a widely reviewed supplement.

Product Focus72

Calming is the clearest purpose, with GABA and theanine making the main possible contributions. Sleep benefits remain limited or uncertain, and the combination is not established to work better than its ingredients separately.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.26
Customer rating
4.7 · 191 ratings
Report analysis

Goals

Stress Relief
Impact
Highest effect
B+ Ingredient FitC PathwaysA EvidenceA+ Formulation Logic
Glycine · 250 mgGABA · 250 mgTheanine · 50 mg
Study evidence
GABA Supportive 6 studies
Glycine Supportive 1 study
Taurine Supportive 5 studies
Theanine Supportive 16 studies
Sleep Support
Impact
Moderate effect
C- Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
Theanine · 50 mgGlycine · 250 mg
Study evidence
GABA Supportive 4 studies
Glycine Supportive 3 studies
Taurine Not classified

No linked studies yet.

Theanine Supportive 8 studies

Ingredients

IngredientAmount per servingScore
GABA
250 mg 79
L-Glycine
250 mg 24
L-Tyrosine
100 mg 50
Taurine
100 mg
L-Theanine
50 mg 76
Bioperine Nature's Thermonutrient
5 mg
Adults 18–50
Report overview
GABA · 250 mg OverallScore79
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB- Value
A serving provides 250 mg of GABA, and the whole-product serving cost is moderate. The production method is not specified. The Other Ingredients panel includes a flow agent, but its name is unavailable.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The label names GABA without a specific branded source.
GABA Source & Production Method
The label names GABA without a specific branded source.

Dose, Safety & Label Transparency93

A serving lists 250 mg of GABA. The Other Ingredients panel includes a flow agent, but its name is unavailable.
GABA Dosage Adequacy & Transparency
A serving lists 250 mg of GABA.
Label Purity & Excipient Quality
The Other Ingredients panel includes a flow agent, but its name is unavailable.

Value70

The whole-product cost per serving is moderate.
Price per Effective Dose
The whole-product cost per serving is moderate.
Theanine · 50 mg OverallScore76
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value
50 mg of L-theanine per serving comes at a moderate cost per 100 mg. That amount may offer mild support. No branded source or additional purity claim is indicated.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

It uses L-theanine, the form associated with calming and focus. No branded source or additional purity claim is indicated.
Isomer Specificity (L-Theanine)
It uses L-theanine, the form associated with calming and focus.
Branded Forms & Purity Standards
No branded source or additional purity claim is indicated.

Dose, Safety & Label Transparency86

A serving provides 50 mg of L-theanine. That amount may offer mild support. The amount and source are individually stated.
Theanine Dosage Efficacy
A serving provides 50 mg of L-theanine. That amount may offer mild support.
Label Transparency & Blends
The amount and source are individually stated.

Value50

The cost per 100 mg of theanine is moderate.
Price per 100mg L-Theanine
The cost per 100 mg of theanine is moderate.
Glycine · 250 mg OverallScore24
F Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyF Value
Each serving provides 250 mg of glycine, a small amount, and glycine is expensive per gram. Its grade and purity certification are not established in the available information. Ordinary capsule or tablet ingredients are reported.
How this ingredient is rated

Active Ingredient Quality & Bioavailability0

Its grade and purity certification are not established in the available information.
Glycine Sourcing and Purity Standards
Its grade and purity certification are not established in the available information.

Dose, Safety & Label Transparency46

The label gives the glycine amount per serving. Ordinary capsule or tablet ingredients are reported.
Clinically Relevant Dosage
A serving supplies 250 mg of glycine, a small amount.
Label Transparency and Yield Disclosure
The glycine amount is explicitly listed.
Clean Label and Excipient Quality
Ordinary capsule or tablet ingredients are reported.

Value30

The cost per gram of glycine is high.
Cost Efficiency per 1,000mg of Glycine
The cost per gram of glycine is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  2. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  3. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  4. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support Stress Relief forGABA
  5. The effect of glycine administration on the characteristics of physiological systems in human adults: A systematic review.
    Soh J; Raventhiran S; Lee JH; Lim ZX; Goh J; Kennedy BK; Maier AB · GeroScience · 2024
    Systematic reviewSleep Support forGlycine
  6. New therapeutic strategy for amino acid medicine: glycine improves the quality of sleep.
    Bannai M; Kawai N · Journal of pharmacological sciences · 2012
    Narrative reviewSleep Support forGlycine
  7. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers.
    Bannai M; Kawai N; Ono K; Nakahara K; Murakami N · Frontiers in neurology · 2012
    Clinical trial7 participantsSleep Support forGlycine
  8. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial.
    Hidese S; Ogawa S; Ota M; Ishida I; Yasukawa Z; Ozeki M; Kunugi H · Nutrients · 2020
    Randomized trial30 participantsSleep Support forTheanine
  9. Comparison Between Efficacy of Oral Melatonin and Oral L-theanine in Improving Sleep in Cancer Patients Suffering From Insomnia: A Randomised Double-blinded Placebo-controlled Study.
    Kurdi MS; As A; Ladhad DA; Mitragotri MV; Baiju A · Indian journal of palliative care · 2024
    Randomized trial120 participantsSleep Support forTheanine
  10. The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis.
    Bulman A; D'Cunha NM; Marx W; Turner M; McKune A; Naumovski N · Sleep medicine reviews · 2025
    Meta-analysis897 participants19 studies pooledSleep Support forTheanine
  11. In Search of a Safe Natural Sleep Aid.
    Rao TP; Ozeki M; Juneja LR · Journal of the American College of Nutrition · 2016
    Narrative reviewSleep Support forTheanine
  12. L-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trial.
    Sarris J; Byrne GJ; Cribb L; Oliver G; Murphy J; Macdonald P; Nazareth S; Karamacoska D; Galea S; Short A; Ee C; Birling Y; Menon R; Ng CH · Journal of psychiatric research · 2020
    Randomized trial46 participantsSleep Support forTheanine
  13. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsStress Relief forGABA
  14. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  15. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  16. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsStress Relief forGABA Stress Relief forTheanine
  17. Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure.
    Díaz-Flores M; Cruz M; Duran-Reyes G; Munguia-Miranda C; Loza-Rodríguez H; Pulido-Casas E; Torres-Ramírez N; Gaja-Rodriguez O; Kumate J; Baiza-Gutman LA; Hernández-Saavedra D · Canadian journal of physiology and pharmacology · 2014
    Randomized trial60 participantsStress Relief forGlycine
  18. Protective and therapeutic effectiveness of taurine supplementation plus low calorie diet on metabolic parameters and endothelial markers in patients with diabetes mellitus: a randomized, clinical trial.
    Moludi J; Qaisar SA; Kadhim MM; Ahmadi Y; Davari M · Nutrition & metabolism · 2022
    Randomized trial120 participantsStress Relief forTaurine
  19. Effects of taurine supplementation on VDT work induced visual stress.
    Zhang M; Bi LF; Ai YD; Yang LP; Wang HB; Liu ZY; Sekine M; Kagamimori S · Amino acids · 2005
    Randomized trial25 participantsStress Relief forTaurine
  20. Taurine supplementation attenuates delayed increase in exercise-induced arterial stiffness.
    Ra SG; Choi Y; Akazawa N; Ohmori H; Maeda S · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2017
    Randomized trial29 participantsStress Relief forTaurine