GABA Calm

GABA Calm

Format:Lozenge Quantity: 120 Liquid(s) · 120 servings
Goals

Product analysis

54 out of 100

GABA Calm may help with short-term stress responses, although the support for swallowed GABA is limited. Most ingredient preparations are unspecified, making comparison with other calming supplements harder.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality24

Magnesium has a named source, but most other ingredient preparations are unspecified. Quality therefore remains uncertain across much of the formula.

Ingredient Transparency70

The amounts of all listed ingredients are disclosed. Most forms are missing, limiting closer comparison.

Value For Money60

The serving cost is favorable in the GABA comparison. Glycine is costly for its amount, while several other value comparisons remain uncertain.

Customer Satisfaction81

Customer ratings are generally positive across several thousand reviews. They show reported satisfaction, without confirming calming or mood benefits.

Product Focus62

Short-term stress support is the clearest intended purpose. Limited GABA findings and small contributions from other ingredients leave everyday mood benefits uncertain.

Format
Lozenge
Container
120 Liquid(s)
Per serving
$0.11
Customer rating
4.4 · 3,644 ratings
Report analysis

Goals

Mood Support
Impact
Moderate effect
B Ingredient FitF PathwaysD+ EvidenceA+ Formulation Logic
Magnesium · 5 mg
Study evidence
GABA Supportive 12 studies
Glycine Mixed 3 studies
Magnesium Supportive 60 studies
Stress Relief
Impact
High effect
C+ Ingredient FitD- PathwaysA EvidenceA+ Formulation Logic
Magnesium · 5 mgGlycine · 50 mgGABA · 125 mg
Study evidence
GABA Supportive 6 studies
Glycine Supportive 1 study
Magnesium Supportive 13 studies
Taurine Supportive 5 studies

Ingredients

IngredientAmount per servingScore
Magnesium (Magnesium Amino Acid Complex)
5 mg
GABA
125 mg 81
Glycine
50 mg 24
N-Acetyl L-Tyrosine
25 mg
Taurine
20 mg 42
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
GABA · 125 mg OverallScore81
B- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value
A serving provides 125 mg GABA at a low cost. It uses unbranded GABA with an unspecified source. The Other Ingredients include a flow agent.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The GABA is unbranded; its source is unspecified.
GABA Source & Production Method
The GABA is unbranded; its source is unspecified.

Dose, Safety & Label Transparency82

The serving states 125 mg GABA. The Other Ingredients include a flow agent.
GABA Dosage Adequacy & Transparency
The GABA amount is 125 mg per serving.
Label Purity & Excipient Quality
The Other Ingredients include a flow agent.

Value100

The cost per serving is low for this GABA form.
Price per Effective Dose
The cost per serving is low for this GABA form.
Taurine · 20 mg OverallScore42
D+ Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyF Value
A serving provides 20 mg of taurine, at a high cost per gram. The taurine form is unspecified. No testing or certification information is available.
How this ingredient is rated

Active Ingredient Quality & Bioavailability51

Taurine is named, but its form is not specified. A flow agent or standard excipient is indicated, but its name is not available.
Chemical Form and Purity
Taurine is named, but its form is not specified.
Sourcing and Branded Ingredients
The taurine source and manufacturing origin are not specified in the available information.
Formulation Cleanliness
A flow agent or standard excipient is indicated, but its name is not available.

Dose, Safety & Label Transparency45

The serving discloses 20 mg of taurine. No testing or certification information is available.
Taurine Dosage Potency
A serving provides 20 mg of taurine.
Dose Disclosure
The taurine amount per serving is disclosed.
Quality Assurance and Testing
No testing or certification information is available.

Value20

The cost per gram of taurine is high.
Price per Gram of Taurine
The cost per gram of taurine is high.
Glycine · 50 mg OverallScore24
F Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyF Value
The serving provides 50 mg of glycine, with a high full-product cost per gram of glycine. That is a small amount relative to amounts used for sleep quality. The source grade and purity certification are unspecified. Ordinary excipients or capsule materials are identified.
How this ingredient is rated

Active Ingredient Quality & Bioavailability0

The glycine source has no stated grade or purity certification in the available information.
Glycine Sourcing and Purity Standards
The glycine source has no stated grade or purity certification in the available information.

Dose, Safety & Label Transparency46

50 mg of glycine per serving is a small amount relative to amounts used for sleep quality. The amount is disclosed and ordinary excipients or capsule materials are identified.
Clinically Relevant Dosage
50 mg of glycine per serving is a small amount relative to amounts used for sleep quality.
Label Transparency and Yield Disclosure
The glycine amount is explicitly stated.
Clean Label and Excipient Quality
Ordinary excipients or capsule materials are identified.

Value30

The full product price per gram of glycine is high; other ingredients contribute to that price.
Cost Efficiency per 1,000mg of Glycine
The full product price per gram of glycine is high; other ingredients contribute to that price.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsMood Support Stress Relief forGABA
  2. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  3. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  4. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  5. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  6. [Augmentation of antipsychotics with glycine may ameliorate depressive and extrapyramidal symptoms in schizophrenic patients--a preliminary 10-week open-label study].
    Strzelecki D; Kropiwnicki P; Rabe-Jabłońska J · Psychiatria polska · 2014
    Single-arm trial29 participantsMood Support forGlycine
  7. Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls.
    Pålsson E; Jakobsson J; Södersten K; Fujita Y; Sellgren C; Ekman CJ; Ågren H; Hashimoto K; Landén M · European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2015
    Cross-sectional study327 participantsMood Support forGlycine
  8. Erythrocyte glycine in depressed, hypomanic, and euthymic bipolar patients treated with lithium carbonate.
    Peselow ED; Deutsch SI; Stanley M; Banay-Schwartz M; Virgilio J; Fieve RR · Psychopharmacology · 1983
    Cross-sectional study27 participantsMood Support forGlycine
  9. Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.
    Wang H; Jin M; Xie M; Yang Y; Xue F; Li W; Zhang M; Li Z; Li X; Jia N; Liu Y; Cui X; Hu G; Dong L; Wang G; Yu Q · Journal of affective disorders · 2023
    Meta-analysis4,049 participants52 studies pooledMood Support forMagnesium
  10. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsMood Support Stress Relief forMagnesium
  11. Magnesium supplementation as an adjunct to fluoxetine therapy for depression.
    Walyddaini AS; Lisal ST; Ilhamuddin; Zainuddin AA; Tanra AJ; Widianingsih Y; Syamsuddin S · East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan · 2026
    Randomized trial40 participantsMood Support forMagnesium
  12. The effects of magnesium supplementation on serum level of brain derived neurotrophic factor (BDNF) and depression status in patients with depression.
    Afsharfar M; Shahraki M; Shakiba M; Asbaghi O; Dashipour A · Clinical nutrition ESPEN · 2021
    Randomized trial46 participantsMood Support forMagnesium
  13. Dietary magnesium intake and risk of depression.
    Sun C; Wang R; Li Z; Zhang D · Journal of affective disorders · 2019
    Cross-sectional study17,730 participantsMood Support forMagnesium
  14. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsStress Relief forGABA
  15. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA
  16. Cortical gamma-aminobutyric acid and glutamate in posttraumatic stress disorder and their relationships to self-reported sleep quality.
    Meyerhoff DJ; Mon A; Metzler T; Neylan TC · Sleep · 2014
    Case-control study45 participantsStress Relief forGABA
  17. Comparison of the effects of two amino acids, Gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - A randomized controlled study.
    Deshpande SS; Kurdi M; Baiju A; Athira AS; Sarasamma AG; Gangadharan AK · Journal of anaesthesiology, clinical pharmacology · 2025
    Randomized trial168 participantsStress Relief forGABA
  18. Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure.
    Díaz-Flores M; Cruz M; Duran-Reyes G; Munguia-Miranda C; Loza-Rodríguez H; Pulido-Casas E; Torres-Ramírez N; Gaja-Rodriguez O; Kumate J; Baiza-Gutman LA; Hernández-Saavedra D · Canadian journal of physiology and pharmacology · 2014
    Randomized trial60 participantsStress Relief forGlycine
  19. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  20. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium