Once-Daily Health Booster

Once-Daily Health Booster

Life Extension4.7 (336 ratings)
Format:Softgel Quantity: 30 Packet(s) · 30 servings
Goals
$67.50 $2.25 per serving

Product analysis

44 out of 100

Once-Daily Health Booster includes MK-7, which has limited support for changes in artery flexibility in selected users. Unclear blend components make the rest of the formula harder to assess.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality32

Several vitamin K forms, including trans-MK-7, are identified. That presence does not establish the properties of the entire mixture, while part of the proprietary blend remains unresolved.

Ingredient Transparency68

The listed amounts and several sources are stated. Main vitamin K form details, saffron preparation and the proprietary-blend proportions are incomplete.

Value For Money18

Vitamin K and chlorophyllin have unfavorable cost comparisons. The remaining contributions do not provide a reliable value comparison to establish whether they offset those costs.

Customer Satisfaction75

Customer ratings are strongly positive across a moderate number of entries. They offer some context for satisfaction without establishing broad health or aging effects.

Product Focus40

MK-7 provides a limited connection to artery flexibility in selected users. Unidentified blend components and exposure-specific chlorophyllin findings limit a broader everyday-health rationale.

Format
Softgel
Container
30 Packet(s)
Per serving
$2.25
Customer rating
4.7 · 336 ratings
Report analysis

Goals

Heart Health
Impact
High effect
C+ Ingredient FitC- PathwaysB EvidenceA+ Formulation Logic
Vitamin K · 3735 mcg
Study evidence
Vitamin K Mixed 62 studies
Longevity
Impact
High effect
B- Ingredient FitD- PathwaysC EvidenceA+ Formulation Logic
Vitamin K · 3735 mcg
Study evidence
Vitamin E Supportive 19 studies
Vitamin K Supportive 27 studies
Liver & Detox
Impact
Moderate effect
D+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Vitamin E · 55 mg
Study evidence
Vitamin E Supportive 23 studies
Everyday Health
Impact
Situational effect
F Ingredient FitF PathwaysF EvidenceB Formulation Logic
Vitamin K · 3735 mcg
Study evidence
Vitamin K Supportive 34 studies

Ingredients

IngredientAmount per servingScore
Vitamin E (D-Alpha-Tocopherol)
30.2 mg
Vitamin K
3735 mcg 73
MacuGuard Proprietary Blend
173 mg
Chlorophyllin (Sodium Magnesium Chlorophyllin)
100 mg 61
Mixed Tocotrienols
55 mg
Saffron extract
20 mg
Lycopene Proprietary Blend (Lyc-O-Mato natural Tomato extract, micronized Lycopene)
10 mg
Adults 18–50
Report overview
B+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value
The serving supplies 100 mg of sodium magnesium chlorophyllin, a substantial amount, at a high cost for that amount. The amount of magnesium is not available. The plant source is unspecified.
How this ingredient is rated

Active Ingredient Quality & Bioavailability80

The form is sodium magnesium chlorophyllin. The plant source is unspecified.
Chlorophyllin Compound Form
The form is sodium magnesium chlorophyllin.
Source and Purity Clarity
The plant source is unspecified.

Dose, Safety & Label Transparency63

A serving supplies 100 mg of chlorophyllin, a substantial amount. The amount of magnesium is not available.
Chlorophyllin Potency
The serving provides 100 mg of chlorophyllin, a substantial amount.
Elemental Mineral Transparency
The amount of magnesium is not available.

Value20

The cost is high for the amount of chlorophyllin supplied, using the full serving price.
Price per 100mg Active Chlorophyllin
The cost is high for the amount of chlorophyllin supplied, using the full serving price.
Vitamin K · 3735 mcg OverallScore73
A+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyF Value
The label lists 3735 mcg of vitamin K per serving, at a high cost per serving. The label names vitamin K1 (phytonadione), MK-4, MK-6, trans-MK-7, MK-9. The MK-7 is named as trans.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The label names vitamin K1 (phytonadione), MK-4, MK-6, trans-MK-7, MK-9. The MK-7 is named as trans.
Vitamin K Form (MK-7 vs. MK-4 vs. K1)
The label names vitamin K1 (phytonadione), MK-4, MK-6, trans-MK-7, MK-9.
MK-7 Isomer Disclosure
The MK-7 is named as trans.

Dose, Safety & Label Transparency82

The listed subtype amounts are stated separately. The label states 181 mcg of MK-7 per serving.
Vitamin K2 (MK-7) Dosage Efficacy
The label states 181 mcg of MK-7 per serving.
Form and Subtype Transparency
The listed subtype amounts are stated separately.

Value0

The cost per serving is high.
Price per Effective MK-7 Serving
Each serving has a high cost.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Dietary vitamin K intake associates with reduced all-cause mortality in non-alcoholic fatty liver disease patients.
    Huang Y; Zhu X; Han L; Hu H · Scientific reports · 2025
    Cohort study7,857 participantsEveryday Health forVitamin K
  2. Vitamin K status, cardiovascular disease, and all-cause mortality: a participant-level meta-analysis of 3 US cohorts.
    Shea MK; Barger K; Booth SL; Matuszek G; Cushman M; Benjamin EJ; Kritchevsky SB; Weiner DE · The American journal of clinical nutrition · 2020
    Meta-analysis3,891 participants3 studies pooledEveryday Health Longevity forVitamin K
  3. The Effect of Topical Vitamin K1 on the Treatment of Cetuximab-Induced Skin Rashes in Metastatic Colorectal Cancer Patients.
    Roayaei M; Rezaei M; Najafizade N · Advanced biomedical research · 2024
    Randomized trial49 participantsEveryday Health forVitamin K
  4. Effect of vitamin K on improving post‑kidney transplant outcomes: a meta‑analysis.
    Sun Z; Zhu K; Liang G; Yan F; Chao S; Jia L; Niu Y · Experimental and therapeutic medicine · 2023
    Meta-analysis7 studies pooledEveryday Health forVitamin K
  5. Vitamin K1 intake is associated with lower risk for all-cause and cardiovascular disease mortality in community-dwelling older Australian women.
    Dupuy M; Radavelli-Bagatini S; Zhong L; Dalla Via J; Zhu K; Blekkenhorst LC; Bondonno NP; Linneberg A; Bellinge JW; Schultz C; Courtney W; Prince RL; Hodgson JM; Lewis JR; Sim M · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2024
    Cohort study1,436 participantsEveryday Health forVitamin K
  6. Vitamin K Intake and Atherosclerotic Cardiovascular Disease in the Danish Diet Cancer and Health Study.
    Bellinge JW; Dalgaard F; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Sim M; Croft KD; Gislason G; Torp-Pedersen C; Tjønneland A; Overvad K; Hodgson JM; Schultz C; Bondonno NP · Journal of the American Heart Association · 2021
    Cohort study53,372 participantsHeart Health forVitamin K
  7. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
    Knapen MH; Braam LA; Drummen NE; Bekers O; Hoeks AP; Vermeer C · Thrombosis and haemostasis · 2016
    Randomized trial244 participantsHeart Health forVitamin K
  8. The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    Bellinge JW; Francis RJ; Lee SC; Bondonno NP; Sim M; Lewis JR; Watts GF; Schultz CJ · The American journal of clinical nutrition · 2022
    Randomized trial149 participantsHeart Health forVitamin K
  9. Dietary Vitamin K1 Intake and Incident Aortic Valve Stenosis.
    Schultz CJ; Dalgaard F; Bellinge JW; Murray K; Sim M; Connolly E; Blekkenhorst LC; Bondonno CP; Lewis JR; Gislason GH; Tjønneland A; Overvad K; Hodgson JM; Bondonno NP · Arteriosclerosis, thrombosis, and vascular biology · 2024
    Cohort study55,545 participantsHeart Health forVitamin K
  10. Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort.
    Palmer CR; Bellinge JW; Dalgaard F; Sim M; Murray K; Connolly E; Blekkenhorst LC; Bondonno CP; Croft KD; Gislason G; Tjønneland A; Overvad K; Schultz C; Lewis JR; Hodgson JM; Bondonno NP · European journal of epidemiology · 2021
    Cohort study56,048 participantsHeart Health forVitamin K
  11. Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1).
    Gross-Steinmeyer K; Eaton DL · Toxicology · 2012
    Narrative reviewLiver & Detox forChlorophyllin
  12. Aflatoxin and Liver Cancer in China: The Evolving Research Landscape.
    Chen JG; Kensler TW; Sun GJ; Zhu J; Lu JH; Pan D; Zhang YH; Groopman JD · Toxins · 2026
    Narrative reviewLiver & Detox forChlorophyllin
  13. Chlorophyllin intervention reduces aflatoxin-DNA adducts in individuals at high risk for liver cancer
    P A Egner, J B Wang, Y R Zhu, B C Zhang, Y Wu, Q N Zhang, G S Qian, S Y Kuang, S J Gange, L P Jacobson, K J Helzlsouer, G S Bailey, J D Groopman, T W Kensler · Proceedings of the National Academy of Sciences of the United States of America · 2001
    Randomized trial169 participantsLiver & Detox forChlorophyllin
  14. Systematic review with meta-analysis: The effect of vitamin E supplementation in adult patients with non-alcoholic fatty liver disease.
    Vadarlis A; Antza C; Bakaloudi DR; Doundoulakis I; Kalopitas G; Samara M; Dardavessis T; Maris T; Chourdakis M · Journal of gastroenterology and hepatology · 2021
    Meta-analysis8 studies pooledLiver & Detox forVitamin E
  15. Effect of vitamin E on cardiometabolic factors in paediatric metabolic dysfunction-associated steatotic liver disease: a systematic review with meta-analysis.
    Pam P; Musazadeh V; Mahmoudinezhad M; Panahiyan P; Mansoori MA; Zarrin R; Faghfouri AH · The British journal of nutrition · 2026
    Meta-analysis665 participants11 studies pooledLiver & Detox forVitamin E
  16. Treatment options for nonalcoholic fatty liver disease: a double-blinded randomized placebo-controlled trial.
    Anushiravani A; Haddadi N; Pourfarmanbar M; Mohammadkarimi V · European journal of gastroenterology & hepatology · 2019
    Randomized trial150 participantsLiver & Detox forVitamin E
  17. Vitamin E administration reduces liver enzyme levels in patients with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD): evidence from a systematic review and meta-analysis.
    Karimi M; Abidi M; Gholamian R; Ostovan A; Zakerolhosseini N; Boroomand S; Esmaeili S; Pourramezan MH; Mohebi S; Javadimoghadam A; Behmaneshnia F; Asbaghi O · Nutrition & metabolism · 2026
    Meta-analysis16 studies pooledLiver & Detox forVitamin E
  18. Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis.
    Banini BA; Cazanave SC; Yates KP; Asgharpour A; Vincent R; Mirshahi F; Le P; Contos MJ; Tonascia J; Chalasani NP; Kowdley KV; McCullough AJ; Behling CA; Schwimmer JB; Lavine JE; Sanyal AJ; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) · Journal of clinical gastroenterology · 2020
    Randomized trial228 participantsLiver & Detox forVitamin E
  19. Low dietary vitamin E intake is associated with high risk of incident dementia among older adults: The Shanghai Aging Study.
    Liu S; Luo J; Xiao Z; Wu W; Liang X; Ding S; Zhao Q; Zhao X; Wang Y; Ding D · Frontiers in nutrition · 2024
    Cohort study1,550 participantsLongevity forVitamin E
  20. Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
    Morris MC; Wang Y; Barnes LL; Bennett DA; Dawson-Hughes B; Booth SL · Neurology · 2019
    Cohort study960 participantsLongevity forVitamin E