Mega GLA Sesame Lignans

Mega GLA Sesame Lignans

Life Extension4.6 (891 ratings)
Format:Softgel Quantity: 30 Softgel(s) · 30 servings
Goals
$21.00 $0.70 per serving

Product analysis

45 out of 100

Mega GLA Sesame Lignans is aimed at skin moisture support, but incomplete oil details make it harder to compare with the preparations behind the limited evidence.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality25

The borage oil source does not provide enough detail to judge the quality of its active components. The sesame preparation is also unnamed, leaving the full mixture uncertain.

Ingredient Transparency33

Some component amounts are missing, making the full serving difficult to check. The oil composition and most forms are also unclear, which limits comparisons with alternatives.

Value For Money40

Value cannot be judged confidently from the available component comparison. A reliable price judgment would need usable costs for the amounts supplied.

Customer Satisfaction78

Customer feedback is very positive across a sizeable review sample. The volume provides a useful view of satisfaction without establishing skin benefits.

Product Focus78

The intended uses center on skin moisture and inflammation-related support. Evidence comes from particular oil preparations or selected clinical settings, so the same effects cannot be assumed for this serving.

Format
Softgel
Container
30 Softgel(s)
Per serving
$0.70
Customer rating
4.6 · 891 ratings
Report analysis

Goals

Inflammation
Impact
High effect
B+ Ingredient FitD PathwaysB EvidenceA+ Formulation Logic
Gamma Linolenic Acid · 400 mg
Study evidence
Skin Health
Impact
Highest effect
B+ Ingredient FitC- PathwaysA- EvidenceA+ Formulation Logic
Gamma Linolenic Acid · 400 mg
Study evidence

Ingredients

IngredientAmount per servingScore
Calories
5 Calorie(s)
Total Fat
0.5 Gram(s)
Saturated Fat
0 Gram(s)
Gamma-Linolenic Acid (Borage Seed Oil)
400 mg 85
Sesame seed Lignan extract
10 mg
Adults 18–50
Report overview
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
A serving provides 400 mg of GLA, a larger amount, at a moderately low cost per amount. The GLA comes from borage seed oil. The extraction method and antioxidant protection are unclear.
How this ingredient is rated

Active Ingredient Quality & Bioavailability72

The GLA comes from borage seed oil. The extraction method and antioxidant protection are unclear.
Botanical Source & GLA Concentration
The GLA comes from borage seed oil.
Extraction Method & Oxidative Stability
The extraction method and antioxidant protection are unclear.

Dose, Safety & Label Transparency100

The label lists 400 mg of GLA per serving, a larger amount.
Active GLA Dosage Potency
A serving provides 400 mg of GLA, a larger amount.
GLA Yield Disclosure
The active GLA amount is listed separately as 400 mg per serving.

Value80

The cost per amount of GLA is moderately low.
Price per 100mg Active GLA
The cost per amount of GLA is moderately low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study.
    Belch JJ; Ansell D; Madhok R; O'Dowd A; Sturrock RD · Annals of the rheumatic diseases · 1988
    Randomized trial49 participantsInflammation forGamma Linolenic Acid
  2. Systemic immune inflammation mediates the association of serum omega-3 and omega-6 polyunsaturated fatty acids with biological aging: a national population-based study.
    Shan F; Xiong Y; Pai P; Liu M · Aging clinical and experimental research · 2025
    Cross-sectional study3,376 participantsInflammation forGamma Linolenic Acid
  3. Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis.
    Cameron M; Gagnier JJ; Little CV; Parsons TJ; Blümle A; Chrubasik S · Phytotherapy research : PTR · 2010
    Meta-analysis20 studies pooledInflammation forGamma Linolenic Acid
  4. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs.
    Brzeski M; Madhok R; Capell HA · British journal of rheumatology · 1991
    Randomized trial40 participantsInflammation forGamma Linolenic Acid
  5. Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid- and ɣ-linolenic acid-containing botanical oils.
    Sergeant S; Hallmark B; Mathias RA; Mustin TL; Ivester P; Bohannon ML; Ruczinski I; Johnstone L; Seeds MC; Chilton FH · The American journal of clinical nutrition · 2020
    Randomized trial64 participantsInflammation forGamma Linolenic Acid
  6. Effect of Evening Primrose Oil on Korean Patients With Mild Atopic Dermatitis: A Randomized, Double-Blinded, Placebo-Controlled Clinical Study.
    Chung BY; Park SY; Jung MJ; Kim HO; Park CW · Annals of dermatology · 2022
    Randomized trial50 participantsSkin Health forGamma Linolenic Acid
  7. Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response.
    Morse PF; Horrobin DF; Manku MS; Stewart JC; Allen R; Littlewood S; Wright S; Burton J; Gould DJ; Holt PJ · The British journal of dermatology · 1989
    Meta-analysis9 studies pooledSkin Health forGamma Linolenic Acid
  8. Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis for atopy.
    Manku MS; Horrobin DF; Morse N; Kyte V; Jenkins K; Wright S; Burton JL · Prostaglandins, leukotrienes, and medicine · 1983
    Non-randomized trial50 participantsSkin Health forGamma Linolenic Acid
  9. Effect of borage oil consumption on fatty acid metabolism, transepidermal water loss and skin parameters in elderly people.
    Brosche T; Platt D · Archives of gerontology and geriatrics · 2005
    Non-randomized trial29 participantsSkin Health forGamma Linolenic Acid
  10. Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients.
    Yoshimoto-Furuie K; Yoshimoto K; Tanaka T; Saima S; Kikuchi Y; Shay J; Horrobin DF; Echizen H · Nephron · 1999
    Randomized trial16 participantsSkin Health forGamma Linolenic Acid