Complete Liver Cleanse

Complete Liver Cleanse

Nature's Way4.5 (423 ratings)
Format:Capsule Quantity: 84 Capsule(s) · 28 servings
Goals

Product analysis

48 out of 100

Complete Liver Cleanse offers B vitamins and selenium to help cover nutritional gaps. Its liver-focused ingredients do not establish routine toxin removal.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality37

Selenium uses a form with favourable absorption characteristics, while other ingredient qualities remain uncertain. Missing forms and unnamed blend components prevent a confident judgment of the whole formula.

Ingredient Transparency69

The listed amounts and many ingredient forms are disclosed. Blend contents and component proportions are incomplete, making the full formula harder to compare.

Value For Money43

Milk thistle and glutathione have reasonably favourable price comparisons, while selenium is relatively costly. Other comparisons are mixed or incomplete, leaving value for the full combination uncertain.

Customer Satisfaction73

Customer ratings are generally positive across several hundred reviews. The feedback describes satisfaction without establishing liver or detox effects.

Product Focus24

The clearest roles are filling nutrient gaps and supporting normal nutritional functions. Milk thistle and glutathione do not establish routine toxin clearance.

Format
Capsule
Container
84 Capsule(s)
Per serving
$0.47
Customer rating
4.5 · 423 ratings
Report analysis

Goals

Impact
High effect
C+ Ingredient FitC- PathwaysA+ EvidenceA+ Formulation Logic
Folate · 333 mcg DFEVitamin B12 · 42 mcgVitamin B6 · 10 mgSelenium · 66 mcgMilk Thistle · 265 mgVitamin C · 50 mgRiboflavin · 8.3 mg
Study evidence
Folate Supportive 16 studies
Selenium Supportive 10 studies
Taurine Supportive 2 studies
Vitamin C Supportive 9 studies
Immunity
Impact
High effect
C Ingredient FitD- PathwaysA- EvidenceA+ Formulation Logic
Vitamin C · 50 mgSelenium · 66 mcg
Study evidence
Selenium Mixed 37 studies
Vitamin C Supportive 53 studies
Everyday Health
Impact
Highest effect
B- Ingredient FitA+ PathwaysB+ EvidenceA+ Formulation Logic
Folate · 333 mcg DFEVitamin B12 · 42 mcgSelenium · 66 mcgVitamin C · 50 mg
Study evidence
Folate Supportive 80 studies
Selenium Supportive 70 studies
Taurine No effect 3 studies
Vitamin C Supportive 56 studies
Impact
Moderate effect
C Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Riboflavin · 8.3 mgThiamin · 8.7 mgVitamin B12 · 42 mcg
Study evidence
Thiamin Disputed 12 studies

Ingredients

IngredientAmount per servingScore
Total Carbohydrates
1 Gram(s)
Vitamin C (Ascorbic Acid)
50 mg
Thiamine
8.7 mg 37
Riboflavin
8.3 mg 48
Niacin (Niacinamide)
10 mg
Vitamin B6 (Pyridoxine Hydrochloride)
10 mg
Folate
333 mcg DFE
Vitamin B12 (Cyanocobalamin)
42 mcg
Selenium (L-Selenomethionine)
66 mcg 70
Amino Acid Liver Blend
330 mg
Milk Thistle seed extract (Silymarin)
265 mg 84
Phytosterols (Beta Sitosterol, Brassicasterol, Campesterol, Plant Sterols, Stigmasterol)
200 mg
L-Glutathione
125 mg 64
Calcium D-Glucarate
100 mg
Dandelion root extract
50 mg
Turmeric rhizome extract (Curcuminoids)
50 mg 88
Artichoke leaf extract (Caffeoylquinic Acids)
30 mg
Adults 18–50 Dairy Free
Report overview
A+ Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value
Each serving provides 66 mcg of selenium, with a high estimated cost per 200 mcg. The amount is relatively small. The selenium source is L-Selenomethionine.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

The selenium source is L-Selenomethionine.
Selenium Chemical Form
The selenium source is L-Selenomethionine.
Form Transparency & Isomer Specificity
The label names L-Selenomethionine as the selenium source.

Dose, Safety & Label Transparency70

66 mcg contributes selenium, though it is below amounts commonly used for daily maintenance. The 66 mcg serving leaves room below the general adult upper limit for selenium from other sources.
Dosage Efficacy Sweet Spot
66 mcg contributes selenium, though it is below amounts commonly used for daily maintenance.
Safety Margin & UL Adherence
The 66 mcg serving leaves room below the general adult upper limit for selenium from other sources.

Value10

The estimated cost per 200 mcg of selenium is high.
Price per 200 mcg Serving
The estimated cost per 200 mcg of selenium is high.
Riboflavin · 8.3 mg OverallScore48
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD+ Value
A serving supplies 8.3 mg of riboflavin, a low amount, at a fairly high cost per serving. It uses standard riboflavin, which requires conversion in the liver. The Other Ingredients panel lists no artificial colors, flavors or synthetic sweeteners.
How this ingredient is rated

Active Ingredient Quality & Bioavailability30

It uses standard riboflavin, which needs conversion in the liver before it participates in energy metabolism.
Riboflavin Form Quality
It uses standard riboflavin, which needs conversion in the liver before it participates in energy metabolism.

Dose, Safety & Label Transparency64

A serving supplies 8.3 mg of riboflavin, a low amount. The Other Ingredients panel lists no artificial colors, flavors or synthetic sweeteners.
Dosage for Energy & Metabolism
A serving supplies 8.3 mg of riboflavin, a low amount.
R5P Elemental Yield Transparency
The phosphate yield question does not apply to standard riboflavin.
Additive Purity
The Other Ingredients panel lists no artificial colors, flavors or synthetic sweeteners.

Value50

The cost per serving is fairly high.
Price per Serving Value
The cost per serving is fairly high.
Glutathione · 125 mg OverallScore64
C- Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyB- Value
125 mg of glutathione per serving comes at a moderate cost per serving. The amount is clearly stated. The glutathione is reduced.
How this ingredient is rated

Active Ingredient Quality & Bioavailability58

The glutathione is reduced. A branded source is indicated, though its name is unclear in the available details.
Delivery System & Absorption Potential
The glutathione is reduced.
Branded Sources & Purity Markers
A branded source is indicated, though its name is unclear in the available details.

Dose, Safety & Label Transparency68

Each serving provides 125 mg of glutathione. The amount is clearly stated.
Dosage Potency per Serving
Each serving provides 125 mg of glutathione.
Label Transparency
The glutathione amount per serving is stated.

Value70

The cost per serving is moderate.
Cost Efficiency by Form
The cost per serving is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Physicochemical properties of and volatile compounds in riboflavin fortified cloudy apple juice; study of its effect on job fatigue among Egyptian construction workers.
    Fouad S; Ibrahim GE; Hussein AMS; Ibrahim FA; El Gendy A · Heliyon · 2021
    Non-randomized trialEnergy forRiboflavin
  2. Vitamin B status in patients with chronic fatigue syndrome.
    Heap LC; Peters TJ; Wessely S · Journal of the Royal Society of Medicine · 1999
    Case-control study30 participantsEnergy forRiboflavin
  3. B-vitamins, related vitamers, and metabolites in patients with quiescent inflammatory bowel disease and chronic fatigue treated with high dose oral thiamine.
    Bager P; Hvas CL; Hansen MM; Ueland P; Dahlerup JF · Molecular medicine (Cambridge, Mass.) · 2023
    Observational studyEnergy forRiboflavin
  4. Metabolic features of chronic fatigue syndrome.
    Naviaux RK; Naviaux JC; Li K; Bright AT; Alaynick WA; Wang L; Baxter A; Nathan N; Anderson W; Gordon E · Proceedings of the National Academy of Sciences of the United States of America · 2024
    Case-control study84 participantsEnergy forRiboflavin
  5. Effectiveness of Riboflavin in Inherited Metabolic Diseases: A Systematic Review
    Bregje Jaeger, Nina N Stolwijk, Femke Aaldering, Charlotte A Ruys, Marije Smits, Nicole I Wolf, Carla E M Hollak, Annet M Bosch · Journal of Inherited Metabolic Disease · 2026
    Systematic review381 studies pooledEnergy forRiboflavin
  6. Influence of thiamin supplementation on the health and general well-being of an elderly Irish population with marginal thiamin deficiency.
    Smidt LJ; Cremin FM; Grivetti LE; Clifford AJ · Journal of gerontology · 1991
    Randomized trial80 participantsEnergy forThiamin
  7. Randomised clinical trial: high-dose oral thiamine versus placebo for chronic fatigue in patients with quiescent inflammatory bowel disease.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Alimentary pharmacology & therapeutics · 2021
    Randomized trial40 participantsEnergy forThiamin
  8. Dietary reference values for thiamin.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Turck D; Bresson JL; Burlingame B; Dean T; Fairweather-Tait S; Heinonen M; Hirsch-Ernst KI; Mangelsdorf I; McArdle HJ; Naska A; Nowicka G; Pentieva K; Sanz Y; Siani A; Sjödin A; Stern M; Tomé D; Van Loveren H; Vinceti M; Willatts P; Lamberg-Allardt C; Przyrembel H; Tetens I; Gudelj Rakic J; Ioannidou S; de Sesmaisons-Lecarré A; Forss AC; Neuhäuser-Berthold M · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEnergy forThiamin
  9. Effects of thiamine supplementation on exercise-induced fatigue.
    Suzuki M; Itokawa Y · Metabolic brain disease · 1996
    Randomized trial16 participantsEnergy forThiamin
  10. Long-term maintenance treatment with 300 mg thiamine for fatigue in patients with inflammatory bowel disease: results from an open-label extension of the TARIF study.
    Bager P; Hvas CL; Rud CL; Dahlerup JF · Scandinavian journal of gastroenterology · 2022
    Randomized trialEnergy forThiamin
  11. A new perspective on vitamin B12 deficiency in rheumatology: a case-based review.
    Dułak NA; Rytlewska M; Jaskólska M; Chmielewski M · Rheumatology international · 2024
    Case series3 participantsEnergy forVitamin B12
  12. Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression.
    Markun S; Gravestock I; Jäger L; Rosemann T; Pichierri G; Burgstaller JM · Nutrients · 2021
    Meta-analysis6,276 participants16 studies pooledEnergy forVitamin B12
  13. Patients' experiences with methylcobalamin injections in amyotrophic lateral sclerosis.
    Zubair AS; Saab L; Scharer K; Khokhar B · Brain circulation · 2024
    Qualitative study5 participantsEnergy forVitamin B12
  14. Cobalamin deficiency: clinical picture and radiological findings.
    Briani C; Dalla Torre C; Citton V; Manara R; Pompanin S; Binotto G; Adami F · Nutrients · 2014
    Narrative reviewEnergy forVitamin B12
  15. Vitamin B12 Deficiency: Common Questions and Answers.
    Patel H; McGuirk R · American family physician · 2025
    Narrative reviewEnergy forVitamin B12
  16. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  17. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  18. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  19. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  20. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate