Riboflavin
Riboflavin, also known as Vitamin B2, is a water-soluble vitamin that plays a central role in energy metabolism. It is a precursor to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are involved in numerous metabolic reactions, including those that convert carbohydrates, proteins, and fats into usable energy for the body. Beyond energy production, Riboflavin is critical for cellular growth and function. It contributes to the maintenance of healthy skin, vision, and mucous membranes. It also aids in the metabolism and activation of other B vitamins, particularly Niacin (Vitamin B3) and Vitamin B6, as well as Folate and Iron. As an antioxidant, Riboflavin helps protect cells from oxidative stress. It is involved in the synthesis of red blood cells and supports the proper functioning of the nervous system. Due to its water-soluble nature, Riboflavin is not stored in large amounts in the body, necessitating regular dietary intake.
Milk and dairy productsEggsLean meats (beef, pork)PoultryFishFortified cerealsMushroomsAlmondsSpinach and other leafy greensBroccoliLegumes
cheapest Riboflavin supplements
Discover the most affordable Riboflavin supplements, essential for vision support, metabolism boost, energy production, detoxification, and overall skin health.
Best Riboflavin supplements
Explore the best Riboflavin supplements to support vision, boost metabolism, enhance energy, aid detoxification, and promote healthy skin.
Value Riboflavin supplements
Compare top Riboflavin supplements to support vision, boost metabolism and energy, aid detoxification, and enhance skin health.
RDA (Men)1 mg
RDA (Women)1 mg
RDI1 mg
Minimum10 mg
Maximum25 mg
Toxicity Effectno known toxicity
Impact
Highest effect
Typical dose:1.3–10 mg
As a precursor to FAD and FMN, Riboflavin (B2) is an essential cofactor in the electron transport chain, the body's primary engine for ATP generation. A deficiency can directly impair energy metabolism and lead to fatigue.
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Impact
Highest effect
Typical dose:1.3–10 mg
Riboflavin is a non-negotiable component of the electron transport chain, the final stage of cellular energy (ATP) production. It is fundamentally required for deriving energy from all macronutrients, making it a foundational element for a healthy metabolic rate.
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Impact
High effect
The original priority of 0 did not reflect its importance. Riboflavin is required for the enzyme glutathione reductase, which keeps the body's primary antioxidant defense system functional. This is a highly effective and necessary support function for detoxification.
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Impact
Moderate effect
Typical dose:1.3–10 mg
While deficiency can cause serious eye problems, supplementation is most beneficial for addressing or preventing a deficiency. For the general population, its role is supportive of the eye's antioxidant systems, like glutathione recycling, rather than being a high-impact, direct treatment for common age-related conditions. Its priority should reflect this supportive role.
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Impact
Situational effect
Typical dose:1.3–10 mg
Riboflavin (Vitamin B2) is crucial for cellular function and repair. While adequate levels are essential for skin health, supplementation is primarily beneficial for preventing or correcting a deficiency, which can manifest as skin disorders like dermatitis. For those with adequate dietary intake, its additional benefit is supportive rather than primary.
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add_circle_outline Positive Interactions
Vitamin B6
Riboflavin is required for the conversion of Vitamin B6 into its active coenzyme form (pyridoxal 5'-phosphate).
Niacin
Riboflavin is essential for the conversion of the amino acid tryptophan into Niacin.
Folate
Riboflavin plays a role in the metabolism of Folate.
Iron
Riboflavin is involved in iron metabolism and red blood cell formation.
Thiamin
As part of the B-complex, Riboflavin works synergistically with Thiamin in energy metabolism.
Vitamin B12
As part of the B-complex, Riboflavin works synergistically with Vitamin B12 in various metabolic processes.
Biotin
As part of the B-complex, Riboflavin works synergistically with Biotin in various metabolic processes.
Vitamin B5
As part of the B-complex, Riboflavin works synergistically with Vitamin B5 in various metabolic processes.
remove_circle_outline Negative Interactions
75 Value 
One Daily Essential
21st Century
4.7
★★★★★
(3224 ratings)
Riboflavin: 1.7 mg
A very affordable, basic daily multivitamin providing essential vitamins and some calcium for general wellness support.
88 Value 
Sentry Senior
21st Century
4.7
★★★★★
(15069 ratings)
Riboflavin: 1.7 mg
A comprehensive and affordable daily multivitamin for seniors, providing essential vitamins, minerals, plus Lutein and Lycopene for broad health and vision support.
78 Best 
Riboflavin 400 mg
AN Amazing Nutrition Amazing Formulas
4.8
★★★★★
(295 ratings)
Riboflavin: 400 mg
A high-potency 400 mg standard riboflavin supplement for intensive metabolic and energy support.
68 Value 
Therapeutic-M
21st Century
4.7
★★★★★
(615 ratings)
Riboflavin: 3.4 mg
Therapeutic-M is a cost-effective multivitamin-mineral supplement designed to offer broad, everyday nutritional support for general wellness.
72 Budget 
Women's One Daily
INNATE Response Formulas
4.5
★★★★★
(334 ratings)
Riboflavin: 1.7 mg
An exceptionally affordable daily multivitamin for women, delivering essential vitamins and well-absorbed mineral forms, providing great value despite lacking calcium and having modest Vitamin D3 for bone health.
78 Best 
MigraSoothe
Health From The Sun
4.6
★★★★★
(22 ratings)
Riboflavin: 200 mg
<p>This supplement combines key vitamins, minerals, and traditional herbs like Feverfew and Butterbur, often used to help maintain head comfort and support overall neurological function.</p>
70 Value 
Complete Multivitamin Adults 50+
Equate
4.7
★★★★★
(2059 ratings)
Riboflavin: 1.7 mg
This multivitamin for adults 50+ offers a foundational blend of essential vitamins, minerals, and key carotenoids like Lutein and Lycopene, supporting general health, bone density, and vision at a very accessible price.
80 Best 
Riboflavin 400 mg
AN Amazing Nutrition Amazing Formulas
4.8
★★★★★
(295 ratings)
Riboflavin: 400 mg
A high-dose 400 mg standard riboflavin supplement in a larger package, ideal for consistent high-level B2 support.
65 Value 
B Complex
Sundown
4.7
★★★★★
(18319 ratings)
Riboflavin: 1.7 mg
A budget-friendly, foundational B complex providing essential B vitamins at conservative daily doses suitable for general wellness support.
85 Best 
Migra-Eeze
Life Extension
4.5
★★★★★
(716 ratings)
Riboflavin: 400 mg
This product offers a focused blend of Riboflavin, Butterbur, and Ginger extracts in softgel form, designed to support comfort and metabolic health through its specific ingredient profile.
65 Value 
Complete Multivitamin
Equate
4.7
★★★★★
(1663 ratings)
Riboflavin: 1.7 mg
This multivitamin offers a broad range of basic vitamins and minerals to support general daily health and fill common nutritional gaps at an economical price.
75 Value 
Prenatal Multivitamin/Multimineral with Folate
Spring Valley
4.7
★★★★★
(2403 ratings)
Riboflavin: 1.7 mg
<p>This prenatal multivitamin delivers a key set of vitamins and minerals, including a good amount of folate and iron, tailored to support nutritional needs during pregnancy at a very affordable price.</p>
75 Value 
One Daily Women's Health
Equate
4.7
★★★★★
(5571 ratings)
Riboflavin: 1.7 mg
This multivitamin provides essential vitamins and minerals in a convenient daily tablet, formulated to help meet the general nutritional needs of women.
78 Budget 
B-Complex plus Vitamin C
21st Century
4.7
★★★★★
(26874 ratings)
Riboflavin: 14.3 mg
A budget-friendly tablet offering a full spectrum of B vitamins alongside Vitamin C and supplemental Calcium, supporting energy and general well-being.
68 Best 
Ketogenic Meal Shake Vanilla Cream
Keto Science
4.5
★★★★★
(42 ratings)
Riboflavin: 189 mg
This ketogenic meal shake provides a high-fat, low-carb macro profile with added vitamins and minerals, suitable for those following a keto diet for general nutritional support and energy.
68 Value 
One Daily Men's Health
Equate
4.7
★★★★★
(2147 ratings)
Riboflavin: 1.7 mg
This is a comprehensive and budget-friendly multivitamin for men, providing a wide array of essential vitamins and minerals for daily nutritional support.
85 Best 
Mega B-150 Balanced B-Complex
NaturesPlus
4.7
★★★★★
(694 ratings)
Riboflavin: 150 mg
A high-potency B-complex with methylated forms of Folate and B12, offering advanced support for energy and overall health.
92 Best 
Riboflavin 400 mg
Seeking Health
4.9
★★★★★
(809 ratings)
Riboflavin: 400 mg
A very high-potency blend of 400 mg standard riboflavin and 400 mg active Riboflavin 5'-Phosphate, offering comprehensive B2 support.
75 Best 
Riboflavin 400 mg
Integrative Therapeutics
4.8
★★★★★
(40 ratings)
Riboflavin: 400 mg
A 400 mg high-dose standard riboflavin tablet from Integrative Therapeutics, aimed at intensive metabolic support.
68 Value 
Complete Multivitamin
Equate
4.8
★★★★★
(3010 ratings)
Riboflavin: 1.7 mg
This multivitamin delivers a wide range of essential vitamins and minerals at a highly affordable price, making it a sensible choice for basic daily nutritional support for many adults.
72 Budget 
B-50 Complex 50 mg
Source Naturals
4.7
★★★★★
(2645 ratings)
Riboflavin: 50 mg
A standard B-50 complex with 50mg doses of most B vitamins, plus Choline, PABA, and Inositol, featuring a higher dose of Folic Acid, and offering exceptional value.
70 Best 
Riboflavin Vitamin B2 400 mg
Nature's Way
4.7
★★★★★
(1633 ratings)
Riboflavin: 400 mg
A high-potency 400 mg Riboflavin tablet from Nature's Way, suitable for those requiring a much larger daily intake of B2.
80 Budget 
Riboflavin 100 mg
Swanson
4.8
★★★★★
(964 ratings)
Riboflavin: 100 mg
This 100 mg Riboflavin capsule from Swanson is an economical choice for supporting energy production and metabolic health.
78 Best 
Vitamin B-2 400 mg
Best Naturals
4.8
★★★★★
(291 ratings)
Riboflavin: 400 mg
A high-dose 400 mg standard riboflavin capsule from Best Naturals, for strong metabolic and energy support.
Average$30.72
Median$26.00
Average$0.74
Median$0.54
Average$1.41
Median$0.47
Reference amount: 10 mg
Vitamin B2, commonly known as Riboflavin, is an essential water-soluble vitamin that acts as a precursor to the coenzymes Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD). These coenzymes are crucial for cellular growth, energy production, and the metabolism of fats, carbohydrates, and proteins. It plays a significant role in maintaining healthy vision, skin, and nerve function, and aids in the body's antioxidant defenses.
- Widely available and affordable
- Well-researched and recognized for its essential functions
- Generally well-tolerated
- Requires conversion to its active coenzyme forms (FMN and FAD) in the body
- Absorption can be limited at very high doses
- Sensitive to light exposure
Avg$26.05
Med$21.78
Avg$0.54
Med$0.41
Avg$0.81
Med$0.34
Price distribution
Riboflavin is the chemical name for Vitamin B2, an essential water-soluble vitamin that plays a central role in energy metabolism by serving as a precursor for the coenzymes FMN and FAD. These coenzymes are integral to the function of various flavoproteins, which are involved in critical enzymatic reactions throughout the body, including those for nutrient metabolism, antioxidant defense, and the conversion of other B vitamins into their active forms.
- Essential for fundamental bodily functions
- Good general bioavailability
- Cost-effective
- Requires metabolic conversion to active forms
- Sensitive to light, which can degrade it in food or solutions
Avg$30.64
Med$27.33
Avg$0.71
Med$0.49
Avg$1.02
Med$0.32
Price distribution
Riboflavin 5-Phosphate, also known as Flavin Mononucleotide (FMN), is the physiologically active coenzyme form of Vitamin B2. Unlike standard riboflavin, which requires conversion by the body into R-5-P and FAD, this form is already activated, allowing for direct utilization in various enzymatic reactions. This makes it particularly beneficial for individuals with genetic variations that might impair riboflavin activation or those seeking a more readily absorbed and utilized form.
- Higher bioavailability
- Does not require metabolic conversion
- Potentially more effective for individuals with absorption or conversion issues
- Directly supports enzyme function
- Typically more expensive than standard riboflavin
- Less common in general supplements
Avg$36.74
Med$31.26
Avg$0.89
Med$0.60
Avg$0.94
Med$0.24
Price distribution
Riboflavin-5-Phosphate Sodium is an active and readily absorbable form of Vitamin B2, chemically identical to Riboflavin 5-Phosphate Sodium. It delivers the coenzyme Flavin Mononucleotide (FMN) directly, bypassing the need for the body to convert inactive riboflavin into its active state. This form is characterized by its excellent water solubility and stability, making it an efficient choice for supplements aiming for maximum bioavailability and immediate physiological impact in energy metabolism and cellular function.
- Active coenzyme form, no conversion needed
- High bioavailability and rapid utilization
- Excellent stability and water solubility
- Typically more expensive than basic riboflavin
- Potential for a slight bitter taste in some formulations
Avg$43.77
Med$42.85
Avg$1.22
Med$0.94
Avg$0.40
Med$0.29
Price distribution
Riboflavin-5-Phosphate Sodium is an active and readily absorbable form of Vitamin B2, chemically identical to Riboflavin 5-Phosphate Sodium. It delivers the coenzyme Flavin Mononucleotide (FMN) directly, bypassing the need for the body to convert inactive riboflavin into its active state. This form is characterized by its excellent water solubility and stability, making it an efficient choice for supplements aiming for maximum bioavailability and immediate physiological impact in energy metabolism and cellular function.
- Active coenzyme form, no conversion needed
- High bioavailability and rapid utilization
- Excellent stability and water solubility
- Typically more expensive than basic riboflavin
- Potential for a slight bitter taste in some formulations
Avg$43.77
Med$42.85
Avg$1.22
Med$0.94
Avg$0.40
Med$0.29
Price distribution
Organic brown rice is a whole grain that serves as a natural dietary source of riboflavin (Vitamin B2), contributing to daily nutritional intake. While the concentration of riboflavin in brown rice is lower than in fortified foods or supplements, it offers the vitamin in its natural food matrix, alongside fiber, other B vitamins, and minerals. The riboflavin present in brown rice must be released during digestion and then converted by the body into its active coenzyme forms.
- Natural food source
- Provides other beneficial nutrients and fiber
- Generally well-tolerated
- Supports a whole-foods diet
- Riboflavin concentration is relatively low
- Intake requires consuming larger quantities
- Bioavailability can vary depending on individual digestion and cooking methods
- Not suitable for addressing deficiencies rapidly
Avg$37.96
Med$37.27
Avg$0.72
Med$0.75
Avg$0.24
Med$0.26
Price distribution
Riboflavin-5-Phosphate Sodium is an active and readily absorbable form of Vitamin B2, chemically identical to Riboflavin 5-Phosphate Sodium. It delivers the coenzyme Flavin Mononucleotide (FMN) directly, bypassing the need for the body to convert inactive riboflavin into its active state. This form is characterized by its excellent water solubility and stability, making it an efficient choice for supplements aiming for maximum bioavailability and immediate physiological impact in energy metabolism and cellular function.
- Active coenzyme form, no conversion needed
- High bioavailability and rapid utilization
- Excellent stability and water solubility
- Typically more expensive than basic riboflavin
- Potential for a slight bitter taste in some formulations
Avg$49.79
Med$38.00
Avg$1.49
Med$1.23
Avg$2.57
Med$1.90
Price distribution
Riboflavin 5-Phosphate, also known as Flavin Mononucleotide (FMN), is the physiologically active coenzyme form of Vitamin B2. Unlike standard riboflavin, which requires conversion by the body into R-5-P and FAD, this form is already activated, allowing for direct utilization in various enzymatic reactions. This makes it particularly beneficial for individuals with genetic variations that might impair riboflavin activation or those seeking a more readily absorbed and utilized form.
- Higher bioavailability
- Does not require metabolic conversion
- Potentially more effective for individuals with absorption or conversion issues
- Directly supports enzyme function
- Typically more expensive than standard riboflavin
- Less common in general supplements
Avg$74.47
Med$73.00
Avg$1.32
Med$1.05
Avg$0.45
Med$0.38
Price distribution
R-5-P, or Riboflavin 5-Phosphate, is the biologically active coenzyme form of Vitamin B2 (Riboflavin). It is also known as Flavin Mononucleotide (FMN). Unlike standard riboflavin, R-5-P does not require enzymatic conversion in the liver before it can be used by the body, making it a highly bioavailable and efficient form. It plays a pivotal role in over 100 enzymatic reactions, primarily in energy production, fatty acid and amino acid metabolism, and as an antioxidant.
- Directly bioavailable and active
- Circumvents potential conversion issues
- Rapid utilization for metabolic support
- Generally well-tolerated
- Higher cost compared to basic riboflavin
- Sometimes less available than the sodium salt form
Avg$38.60
Med$38.34
Avg$1.14
Med$1.01
Avg$0.31
Med$0.30
Price distribution