Melatonin Lozenges 3 mg

Melatonin Lozenges 3 mg

Life Extension4.7 (2,483 ratings)
Format:Lozenge Quantity: 60 Liquid(s) · 60 servings
Goals
$5.10 $0.08 per serving

Product analysis

59 out of 100

Melatonin Lozenges 3 mg offers favorably priced melatonin that may help with sleep timing and falling asleep. Its usefulness depends on when it is taken and the person's sleep pattern.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The melatonin preparation is unspecified, limiting a firm quality comparison. The lozenge format alone does not establish a delivery advantage.

Ingredient Transparency63

The amounts are disclosed, but the forms are unspecified. Serving sizes can be compared more readily than preparation quality.

Value For Money85

The declared active content is favorably priced in the comparison. That supports value when the ingredient matches your needs.

Customer Satisfaction85

Customer ratings are favorable, with a substantial review pool. Reviews describe satisfaction without establishing effectiveness or safety.

Product Focus71

Sleep timing and onset are the clearest uses. The sleep-related role does not establish broader immune, memory or everyday-health benefits.

Format
Lozenge
Container
60 Liquid(s)
Per serving
$0.08
Customer rating
4.7 · 2,483 ratings
Report analysis

Goals

Sleep Support
Impact
Highest effect
A Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Melatonin · 3 mg
Study evidence
Melatonin Supportive 181 studies
Everyday Health
Impact
Moderate effect
A Ingredient FitF PathwaysC- EvidenceA+ Formulation Logic
Study evidence
Melatonin Supportive 69 studies
Brain Health
Impact
Moderate effect
A Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Study evidence
Melatonin Supportive 29 studies
Immunity
Impact
High effect
A Ingredient FitD PathwaysB EvidenceA+ Formulation Logic
Study evidence
Melatonin Supportive 10 studies

Ingredients

IngredientAmount per servingScore
Melatonin
3 mg 57
Adults 18–50 Vegetarian
Report overview
Melatonin · 3 mg OverallScore57
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value
Each serving provides 3 mg of melatonin, a lower amount aligned with the stated natural sleep-cycle range, at a fairly low cost per serving. No manufacturing or independent testing claim is available in the information provided.
How this ingredient is rated

Active Ingredient Quality & Bioavailability0

No manufacturing or independent testing claim is available in the information provided.
Third-Party Purity Verification
No manufacturing or independent testing claim is available in the information provided.

Dose, Safety & Label Transparency100

A serving provides 3 mg of melatonin, a lower amount aligned with the stated natural sleep-cycle range.
Physiological Dosing Alignment
The serving contains 3 mg of melatonin, a lower amount aligned with the stated natural sleep-cycle range.

Value85

The cost per serving is fairly low.
Price Per Serving Efficiency
The cost per serving is fairly low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Comparative Efficacy, Tolerability, and Acceptability of Donanemab, Lecanemab, Aducanumab, Melatonin, and Aerobic Exercise for a Short Time on Cognitive Function in Mild Cognitive Impairment and Mild Alzheimer's Disease: A Systematic Review and Network Meta-Analysis.
    Terao I; Kodama W · Journal of Alzheimer's disease : JAD · 2024
    Meta-analysis4,599 participants10 studies pooledBrain Health forMelatonin
  2. Melatonin for sleep and cognitive outcomes in older adults with cognitive impairment: a meta-analysis of randomised controlled trials.
    Mdluli NT; Banda KJ; Chang YC · Age and ageing · 2025
    Meta-analysis516 participants10 studies pooledBrain Health forMelatonin
  3. Add-on prolonged-release melatonin for cognitive function and sleep in mild to moderate Alzheimer's disease: a 6-month, randomized, placebo-controlled, multicenter trial.
    Wade AG; Farmer M; Harari G; Fund N; Laudon M; Nir T; Frydman-Marom A; Zisapel N · Clinical interventions in aging · 2015
    Randomized trial80 participantsBrain Health forMelatonin
  4. Early Oral Melatonin Supplementation Supports White Matter Maturation in Preterm Infants: Neuroprotective Insights of an Antioxidant Molecule.
    Garofoli F; Asteggiano C; Minniti ML; Accorsi P; Albertini R; Angelini M; Aversa S; Ballante E; Cabini RF; Caporali C; Cociglio S; Franco V; Longo S; Malerba L; Materia V; Mazzocchi L; Naboni C; Palmisani M; Pullega C; Pisoni C; Preda L; Riboli A; Risso FM; Rognone E; Savini G; Simoncelli AM; Villani P; Tzialla C; Pinelli L; Fazzi E; Chiapparini L; Borgatti R; Ghirardello S; Pichiecchio A; Orcesi S · Journal of pineal research · 2026
    Randomized trial54 participantsBrain Health forMelatonin
  5. Efficacy and Safety of Melatonin in Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Abouelmagd ME; Aldemerdash MA; Khatatbeh AA; Osman ASA; Abbas A; Allam S; AlEdani EM; Aldemerdash A; Monteith TS · Current pain and headache reports · 2026
    Meta-analysis788 participants9 studies pooledBrain Health forMelatonin
  6. Melatonin for preventing and treating jet lag.
    Herxheimer A; Petrie KJ · The Cochrane database of systematic reviews · 2001
    Systematic review10 studies pooledEveryday Health forMelatonin
  7. Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life.
    Schroder CM; Malow BA; Maras A; Melmed RD; Findling RL; Breddy J; Nir T; Shahmoon S; Zisapel N; Gringras P · Journal of autism and developmental disorders · 2019
    Randomized trial125 participantsEveryday Health forMelatonin
  8. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.
    Fatemeh G; Sajjad M; Niloufar R; Neda S; Leila S; Khadijeh M · Journal of neurology · 2022
    Meta-analysis23 studies pooledEveryday Health forMelatonin
  9. Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses.
    Choi K; Lee YJ; Park S; Je NK; Suh HS · Sleep medicine reviews · 2022
    Meta-analysis24 studies pooledEveryday Health forMelatonin
  10. Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial.
    Leerasiri P; Pariyaeksut P; Hengrasmee P; Asumpinwong C · International urogynecology journal · 2023
    Randomized trial60 participantsEveryday Health forMelatonin
  11. Exogenous melatonin boosts vaccine-induced immunity in individuals with high pre-existing influenza immunity.
    Oda K; Danko J; Villasante E; Bergmann-Leitner E; Lee R; Wijayalath W · Frontiers in immunology · 2025
    Randomized trialImmunity forMelatonin
  12. Evaluation of melatonin effectiveness in the adjuvant treatment of ulcerative colitis.
    Chojnacki C; Wisniewska-Jarosinska M; Walecka-Kapica E; Klupinska G; Jaworek J; Chojnacki J · Journal of physiology and pharmacology : an official journal of the Polish Physiological Society · 2012
    Randomized trial60 participantsImmunity forMelatonin
  13. Pineal-opioid system interactions in the control of immunoinflammatory responses.
    Lissoni P; Barni S; Tancini G; Fossati V; Frigerio F · Annals of the New York Academy of Sciences · 1995
    Clinical trial130 participantsImmunity forMelatonin
  14. Influenza vaccine response is predicted by chronotype and differentially associated with pre- and post-vaccination sleep.
    Harrison EM; Lee RU; Porter CK; Isidean SD; Easterling AP; White L; Boulifard DA; DeTizio K; Liang Z; Sedegah M; Danko J; Glickman GL · Brain, behavior, & immunity - health · 2026
    Randomized trialImmunity forMelatonin
  15. Mechanisms and clinical evidence to support melatonin's use in severe COVID-19 patients to lower mortality.
    Tan DX; Reiter RJ · Life sciences · 2022
    Narrative review19 participantsImmunity forMelatonin
  16. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  17. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  18. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  19. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  20. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin