D3 1000 IU

D3 1000 IU

Nature Made4.6 (83 ratings)
Format:Softgel Quantity: 180 Softgel(s) · 180 servings
Goals
$8.23 $0.04 per serving

Product analysis

87 out of 100

D3 1000 IU can help fill low vitamin D intake and support normal bone and immune function. Its usefulness is greatest when vitamin D intake or levels are low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality100

Vitamin D is supplied as D3, a favorable form for vitamin D supplementation. That form alone does not establish extra benefits once vitamin D needs are met.

Ingredient Transparency100

The vitamin D amount and D3 form are clearly disclosed. That makes the serving easy to compare with other vitamin D options.

Value For Money80

The cost relative to vitamin D content offers good value. Its value rests on supplying vitamin D affordably, without needing to assume benefits from additional ingredients.

Customer Satisfaction69

Customer ratings are favorable, although the review pool is relatively small. The feedback offers a limited picture of satisfaction and does not prove health benefits.

Product Focus68

The formula has a clear role in vitamin D nutrition. Benefits for energy, hormones or aging are less certain when vitamin D levels are already adequate.

Format
Softgel
Container
180 Softgel(s)
Per serving
$0.04
Customer rating
4.6 · 83 ratings
Report analysis

Goals

Immunity
Impact
High effect
B- Ingredient FitD- PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 1000 IU

Vitamin D contributes to normal immune regulation and can help fill low intake. The 25 mcg serving supplies part of the saved comparison range, without establishing an infection-prevention benefit. Correcting deficiency is a different situation from routine prevention, and no superiority between vitamin D forms is established here.

How this product is rated for Immunity

Ingredient fit73

Vitamin D align with the supported immune roles. Vitamin D supplies a partial amount contribution in the saved comparison.
Goal fit
Vitamin D align with the supported immune roles.
Dose adequacy
Vitamin D supplies a partial amount contribution in the saved comparison.

Pathways40

The supported coverage centres on immune-cell regulation.
Depth
The strongest contribution is in immune-cell regulation.
Breadth
The supported coverage centres on immune-cell regulation.

Evidence100

Vitamin D supplies the strongest supported contribution at the stated amount, within the clinical limits described for it.
Evidence strength
Vitamin D supplies the strongest supported contribution at the stated amount; its clinical limits still apply.
Studied preparation
The supplied findings accept the contributing nutrient preparations, without establishing superior clinical effects from their forms.

Formulation logic100

The included contributions meet the saved amount criterion; this does not prove prevention of infection.
Partner coverage
The included contributions have no unmet required ingredient partner.
Conflicts
No listed ingredient conflict was identified in the supplied findings.
Effective doses
The included contributions meet the saved amount criterion; this does not prove prevention of infection.
Study evidence
Vitamin D Supportive 85 studies
Everyday Health
Impact
High effect
B- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin D · 1000 IU

Vitamin D contributes to bone and mineral nutrition. These nutrients can help fill dietary shortfalls; additional benefit above adequate intake is not established.

How this product is rated for Everyday Health

Ingredient fit73

Vitamin D provides a focused nutrient contribution, most relevant when intake is low.
Goal fit
Vitamin D is the main recognized ingredient in this product’s general-health connection.
Dose adequacy
The counted amounts provide partial coverage of the supplied comparisons, without establishing inadequate intake or a clinical treatment dose.

Pathways19

The strongest saved connection is bone and mineral metabolism, reflecting nutritional roles rather than demonstrated broad health outcomes.
Depth
The strongest saved connection is bone and mineral metabolism, reflecting nutritional roles rather than demonstrated broad health outcomes.
Breadth
No evaluated function reaches the supplied coverage threshold.

Evidence82

The evidence supports nutrient availability and correction of dietary gaps, rather than extra benefit when intake is adequate.
Evidence strength
Vitamin D leads the saved evidence finding, with benefit limited to its supported nutritional role and filling low intake.
Studied preparation
The counted preparations match those recognized in the supplied comparison, without establishing superiority of a particular chemical form or delivery method.

Formulation logic100

No unmet partner requirement or specified conflict was identified, and the counted ingredients meet the supplied minimum amount comparisons.
Partner coverage
No counted ingredient has an unmet partner requirement in the supplied findings; this does not establish added benefit from combining ingredients.
Conflicts
No specified ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients meet the supplied minimum amount comparison; this is not a proven threshold for broad health benefit.
Study evidence
Vitamin D Supportive 115 studies
Impact
High effect
B- Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
Vitamin D · 1000 IU

Vitamin D is involved in inflammatory signalling, but supplementation has produced inconsistent changes in inflammatory markers. A transient reduction in CRP in older adults did not persist at later follow-up, and other markers were unchanged. This D3 serving receives amount-based recognition, without establishing a broad clinical anti-inflammatory benefit.

How this product is rated for Inflammation

Ingredient fit73

Vitamin D is the relevant ingredient, with a declared amount for comparison.
Goal fit
The relevant ingredient declarations form a focused comparison for this goal, although clinical applicability remains limited.
Dose adequacy
Declared amounts only partly match the supplied comparisons; unresolved active quantities cannot establish adequacy.

Pathways19

Inflammatory gene signalling is the strongest assigned route; that assignment does not establish a clinical anti-inflammatory effect.
Depth
Inflammatory gene signalling is the strongest assigned route; that assignment does not establish a clinical anti-inflammatory effect.
Breadth
No assigned route reaches the supplied coverage criterion.

Evidence93

Vitamin D leads the saved evidence finding, but inflammatory-marker results are inconsistent.
Evidence strength
Vitamin D leads the saved evidence finding, but inflammatory-marker results are inconsistent.
Studied preparation
The supplied comparison accepts the relevant preparations; this does not establish equivalence of every formulation or a matching daily regimen.

Formulation logic100

No listed conflict or missing required partner is identified. Amount comparisons do not demonstrate an added benefit from combining ingredients.
Partner coverage
No required partner is missing among the recognized ingredients; this does not establish synergy.
Conflicts
No listed conflict is triggered by the supplied ingredient and amount facts.
Effective doses
All recognized ingredients meet the minimum amount comparison, which is not a proven biological threshold.
Study evidence
Vitamin D Supportive 101 studies
Energy
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA+ Formulation Logic
Vitamin D · 1000 IU

Vitamin D receives a contribution in the saved findings, but its fatigue evidence comes from deficient adults given a single large treatment dose. That result does not establish routine energy enhancement when vitamin D status is adequate. The 25 mcg serving partly meets the saved amount comparison, which is not a proven fatigue-dose scale. No assessed energy pathway receives coverage.

How this product is rated for Energy

Ingredient fit73

Vitamin D is focused in the saved findings, with a partial amount contribution.
Goal fit
Vitamin D is the sole credited ingredient, with fatigue evidence specific to deficient adults.
Dose adequacy
The 25 mcg serving partly meets the saved comparison without establishing a clinical fatigue response.

Pathways0

None of the assessed energy pathways receives coverage. This differs from the conditional nutritional contribution retained elsewhere.
Depth
No assessed energy pathway has a qualifying contribution.
Breadth
No assessed energy area reaches substantial coverage.

Evidence95

The fatigue study's deficient population and treatment regimen limit routine energy claims. The preparation meets the saved criteria.
Evidence strength
Vitamin D leads the saved evidence finding, within the population and outcome limits of its supplied evidence.
Studied preparation
Credited preparations meet the saved criteria without establishing superiority of particular forms or delivery methods.

Formulation logic100

Credited ingredients clear the saved amount threshold and have no assessed missing partner or conflict.
Partner coverage
Credited ingredients work alone or have their relevant partners.
Conflicts
No assessed ingredient conflict was triggered.
Effective doses
All credited ingredients clear the saved minimum amount threshold; that threshold does not establish a clinical fatigue effect.
Study evidence
Vitamin D Supportive 32 studies
Longevity
Impact
Moderate effect
B- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin D · 1000 IU

The 25 mcg vitamin D3 serving, equivalent to 1,000 IU, supports nutritional adequacy relevant to muscle and bone function. Its practical relevance is greatest when vitamin D status is low; extra benefits for aging are not supported for people whose status is already adequate.

How this product is rated for Longevity

Ingredient fit73

The ingredients are closely focused on the reviewed goal, though the product is also linked to other uses. The assessed amounts provide partial dose coverage; some amounts are smaller or unresolved.
Goal fit
The ingredients are closely focused on the reviewed goal, though the product is also linked to other uses.
Dose adequacy
The assessed amounts provide partial dose coverage; some amounts are smaller or unresolved.

Pathways0

No reviewed aging pathway has a meaningful saved contribution; the contribution is mainly nutritional. The saved findings do not show broad coverage of the reviewed aging pathways.
Depth
No reviewed aging pathway has a meaningful saved contribution; the contribution is mainly nutritional.
Breadth
The saved findings do not show broad coverage of the reviewed aging pathways.

Evidence83

Vitamin D provides the strongest evidence contribution among the assessed ingredients, within the limits of the reviewed outcomes. The assessed ingredients at meaningful amounts match preparations included in the supplied evidence.
Evidence strength
Vitamin D provides the strongest evidence contribution among the assessed ingredients, within the limits of the reviewed outcomes.
Studied preparation
The assessed ingredients at meaningful amounts match preparations included in the supplied evidence.

Formulation logic100

1 of 1 assessed ingredients reach meaningful amounts in the saved assessment. No ingredient conflict was identified in the saved assessment.
Partner coverage
The assessed ingredients can contribute on their own or have their relevant partner present.
Conflicts
No ingredient conflict was identified in the saved assessment.
Effective doses
1 of 1 assessed ingredients reach meaningful amounts in the saved assessment.
Study evidence
Vitamin D Supportive 50 studies
Testosterone Support
Impact
Moderate effect
B- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Vitamin D · 1000 IU

Vitamin D may be relevant to testosterone when levels of the vitamin are low, but a hormone increase isn't reliable. The possible benefit is more limited than a general testosterone boost. Getting more vitamin D when you already have enough hasn't consistently raised testosterone, and the serving amount doesn't show whether you're deficient.

How this product is rated for Testosterone Support

Ingredient fit73

Vitamin D supplies the main nutrient connection to testosterone. Its practical value depends on the limits of that connection.
Goal fit
Vitamin D is the ingredient relevant to this goal; its presence doesn't guarantee a testosterone increase.
Dose adequacy
Vitamin D 25 mcg per serving; these amounts do not predict a testosterone increase.

Pathways0

Vitamin D status may matter, but taking it does not reliably translate into higher testosterone.
Depth
A role for vitamin D status does not mean taking vitamin D will increase testosterone.
Breadth
The ingredients do not provide reliable grounds to expect several distinct testosterone effects.

Evidence81

Vitamin D does not reliably raise testosterone in people who already have enough. A possible effect in deficient users should remain uncertain.
Evidence strength
Vitamin D has uncertain effects on testosterone, especially when vitamin D levels are already adequate.
Studied preparation
The declared vitamin d form does not remove the limits on expecting a testosterone increase.

Formulation logic100

No missing partner or particular ingredient conflict is identified. Combining the ingredients does not itself show an added hormone benefit.
Partner coverage
No missing ingredient partner is identified for the relevant ingredients.
Conflicts
No particular ingredient conflict is identified.
Effective doses
The relevant ingredient amounts are declared, but the amounts alone cannot show that testosterone will rise.
Study evidence
Vitamin D Supportive 56 studies

Ingredients

IngredientAmount per servingScore
Vitamin D3 (Cholecalciferol)
1000 IU 88
Gluten Free Adults 18–50
Report overview
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB+ Value
A serving provides 1,000 IU of vitamin D3. A whole-product serving costs about $0.05, equivalent to about $0.05 per 1,000 IU of vitamin D.
How this ingredient is rated

Active Ingredient Quality & Bioavailability87

Vitamin D is identified as D3 (cholecalciferol); its raw material source is not established in the saved facts.
Vitamin D3 vs. D2 Superiority
The form is cholecalciferol, also known as vitamin D3.
Sourcing and Active Marker Disclosure
Vitamin D3 is identified, but its raw material source is not established in the saved facts.

Dose, Safety & Label Transparency94

The serving provides 1,000 IU of vitamin D. A qualifying third-party seal is recorded.
Daily Dosage Appropriateness
The serving provides 1,000 IU of vitamin D.
Excipient and Additive Purity
The available ingredient information does not identify titanium dioxide, artificial colors or hydrogenated oils. The sugar amount is unavailable in the saved facts.
Purity and Quality Certification
A qualifying third-party certification seal is recorded, but its identity is not specified in the saved facts.

Value80

A whole-product serving costs about $0.05, equivalent to about $0.05 per 1,000 IU of vitamin D.
Price per 1,000 IU Efficiency
A whole-product serving costs about $0.05, equivalent to about $0.05 per 1,000 IU of vitamin D.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of Vitamin D Supplementation on Fatigue in Multiple Sclerosis: A Systematic Review and Meta-Analysis.
    López-Muñoz P; Torres-Costoso AI; Fernández-Rodríguez R; Guzmán-Pavón MJ; de Arenas-Arroyo SN; Basco-López JÁ; Reina-Gutiérrez S · Nutrients · 2023
    Meta-analysis345 participants5 studies pooledEnergy forVitamin D
  2. Vitamin D Supplementation in Adolescents and Young Adults With Juvenile Systemic Lupus Erythematosus for Improvement in Disease Activity and Fatigue Scores: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Lima GL; Paupitz J; Aikawa NE; Takayama L; Bonfa E; Pereira RM · Arthritis care & research · 2016
    Randomized trial40 participantsEnergy forVitamin D
  3. Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.
    Kodama S; Nakata M; Konishi N; Yoshino M; Fujisawa A; Naganuma M; Kobayashi Y; Hirai Y; Kitagawa A; Miyokawa M; Mishima R; Teramukai S; Fukushima M · Nutrients · 2026
    Randomized trial91 participantsEnergy forVitamin D
  4. The effects of vitamin D supplementation on disease activity and fatigue in Libyan rheumatoid arthritis patients.
    Elfituri S · Reumatologia · 2024
    Randomized trial68 participantsEnergy forVitamin D
  5. The effect of home-based aerobic training and vitamin D supplementation on fatigue and quality of life in patients with multiple sclerosis during COVID-19 outbreak.
    Bahmani E; Hoseini R; Amiri E · Science & sports · 2022
    Randomized trial40 participantsEnergy forVitamin D
  6. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledEveryday Health forVitamin D
  7. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsEveryday Health forVitamin D
  8. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledEveryday Health forVitamin D
  9. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledEveryday Health forVitamin D
  10. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledEveryday Health forVitamin D
  11. Vitamin D supplementation to prevent acute respiratory infections: individual participant data meta-analysis.
    Martineau AR; Jolliffe DA; Greenberg L; Aloia JF; Bergman P; Dubnov-Raz G; Esposito S; Ganmaa D; Ginde AA; Goodall EC; Grant CC; Janssens W; Jensen ME; Kerley CP; Laaksi I; Manaseki-Holland S; Mauger D; Murdoch DR; Neale R; Rees JR; Simpson S; Stelmach I; Trilok Kumar G; Urashima M; Camargo CA; Griffiths CJ; Hooper RL · Health technology assessment (Winchester, England) · 2020
    Meta-analysis11,321 participants25 studies pooledImmunity forVitamin D
  12. Association Between Vitamin D and Influenza: Meta-Analysis and Systematic Review of Randomized Controlled Trials.
    Zhu Z; Zhu X; Gu L; Zhan Y; Chen L; Li X · Frontiers in nutrition · 2022
    Meta-analysis4,859 participants10 studies pooledImmunity forVitamin D
  13. Vitamin D3 and deconvoluting a rash.
    Ernst MK; Evans ST; Techner JM; Rothbaum RM; Christensen LF; Onay UV; Biyashev D; Demczuk MM; Nguyen CV; Honda KS; McCormick TS; Tsoi LC; Gudjonsson JE; Cooper KD; Lu KQ · JCI insight · 2023
    Randomized trial28 participantsImmunity forVitamin D
  14. Effect of vitamin D3 supplementation on cellular immunity and inflammatory markers in COVID-19 patients admitted to the ICU.
    Bychinin MV; Klypa TV; Mandel IA; Yusubalieva GM; Baklaushev VP; Kolyshkina NA; Troitsky AV · Scientific reports · 2022
    Randomized trial110 participantsImmunity forVitamin D
  15. Current opinion on the role of vitamin D supplementation in respiratory infections and asthma/COPD exacerbations: A need to establish publication guidelines for overcoming the unpublished data.
    Anitua E; Tierno R; Alkhraisat MH · Clinical nutrition (Edinburgh, Scotland) · 2022
    Meta-analysis50,554 participants65 studies pooledImmunity forVitamin D
  16. Vitamin D deficiency and C-reactive protein: a bidirectional Mendelian randomization study.
    Zhou A; Hyppönen E · International journal of epidemiology · 2023
    Observational study294,970 participantsInflammation forVitamin D
  17. Vitamin D in Children With Inflammatory Bowel Disease: A Randomized Controlled Clinical Trial.
    El Amrousy D; El Ashry H; Hodeib H; Hassan S · Journal of clinical gastroenterology · 2021
    Randomized trial120 participantsInflammation forVitamin D
  18. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers.
    Gao YQ; Gao YH; Xing JH · World journal of diabetes · 2025
    Randomized trial120 participantsInflammation forVitamin D
  19. Associations of C-reactive Protein with 25-hydroxyvitamin D in 24 Specific Diseases: A Cross-sectional Study from NHANES.
    Yang F; Sun M; Sun C; Li J; Yang X; Bi C; Wang M; Pu L; Wang J; Wang C; Xie M; Yao Y; Jin L · Scientific reports · 2020
    Cross-sectional study9,809 participantsInflammation forVitamin D
  20. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults.
    Zhang C; Cui J; Li S; Shen J; Luo X; Yao Y; Shi H · BMC geriatrics · 2024
    Cohort study3,072 participantsInflammation forVitamin D