CoQ10 400 mg

CoQ10 400 mg

Protocol For Life Balance4.8 (138 ratings)
Format:Softgel Quantity: 60 Softgel(s) · 60 servings
Goals
$65.00 $1.08 per serving

Product analysis

47 out of 100

CoQ10 400 mg supports normal cellular energy processes and has limited evidence for blood-vessel benefits in specific groups of adults. Its unspecified CoQ10 form and relatively high serving cost make comparison especially important.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality25

Vitamin E uses a favorable natural form, but the CoQ10 form is unspecified. That leaves the main ingredient’s preparation and absorption quality unclear.

Ingredient Transparency70

Listed amounts make the serving easier to check. Most forms are unspecified, including CoQ10’s form, limiting a detailed comparison.

Value For Money24

The CoQ10 serving is relatively costly, weakening value. Vitamin E offers only limited value, while lecithin’s value remains unclear.

Customer Satisfaction74

Customer feedback is very positive. The relatively small body of ratings gives a limited picture of wider satisfaction.

Product Focus66

CoQ10 connects the formula’s cellular-energy and blood-vessel aims. Evidence for noticeable fatigue or broader health benefits is limited and depends on the preparation and people studied.

Format
Softgel
Container
60 Softgel(s)
Per serving
$1.08
Customer rating
4.8 · 138 ratings
Report analysis

Goals

Heart Health
Impact
High effect
C- Ingredient FitD PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Longevity
Impact
Moderate effect
C Ingredient FitD- PathwaysF EvidenceA- Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Vitamin E Supportive 19 studies
Energy
Impact
Moderate effect
B- Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence
Inflammation
Impact
High effect
C Ingredient FitD+ PathwaysA EvidenceA- Formulation Logic
Coenzyme Q-10 · 400 mgVitamin E · 30 IU
Study evidence
Vitamin E Supportive 20 studies
Cardiovascular Support
Impact
High effect
B- Ingredient FitC PathwaysA- EvidenceA- Formulation Logic
Coenzyme Q-10 · 400 mgVitamin E · 30 IU
Study evidence
Vitamin E Mixed 79 studies
Metabolism Support
Impact
High effect
B- Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 400 mg
Study evidence

Ingredients

IngredientAmount per servingScore
Calories
5 Calorie(s)
Total Fat
0.5 Gram(s)
Vitamin E (D-Alpha-Tocopherol)
30 IU 53
Coenzyme Q10
400 mg 38
Sunflower Lecithin
35 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Coenzyme Q-10 · 400 mg OverallScore38
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value
A serving provides 400 mg of an unspecified form CoQ10 at a high per serving cost. The missing form detail limits comparison.
How this ingredient is rated

Active Ingredient Quality & Bioavailability12

The CoQ10 form is unclear, so its form-specific properties cannot be determined. No liposomal, micellar or nanoemulsion claim, or black pepper extract, is established.
Molecular Form: Ubiquinol vs. Ubiquinone
The CoQ10 form is unclear, so its form-specific properties cannot be determined.
Formulation & Absorption Enhancers
No liposomal, micellar or nanoemulsion claim, or black pepper extract, is established.

Dose, Safety & Label Transparency72

A serving provides 400 mg of CoQ10. The amount is stated, and none of the specified concerning additives or standard fillers are indicated.
Clinical Dosage Alignment
A serving provides 400 mg of CoQ10.
Label Transparency & Fillers
The amount is stated, and none of the specified concerning additives or standard fillers are indicated.

Value20

The cost is high per serving.
Price Per Effective Serving
The cost is high per serving.
D Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyD- Value
A serving provides 30 IU of vitamin E. The cost per serving is high. The named forms include d-alpha-tocopherol.
How this ingredient is rated

Active Ingredient Quality & Bioavailability46

The named forms include d-alpha-tocopherol. No mixed-tocopherol complex is identified.
Natural (d-alpha) vs. Synthetic (dl-alpha)
The named forms include d-alpha-tocopherol.
Mixed Tocopherol Isomer Diversity
No mixed-tocopherol complex is identified.
Tocotrienol Complex Inclusion
No tocotrienols are identified.

Dose, Safety & Label Transparency66

A serving provides 30 IU of vitamin E. The named form is d-alpha-tocopherol.
Therapeutic Dosage Range
A serving provides 30 IU of vitamin E.
Label Transparency and Isomer Specificity
The named form is d-alpha-tocopherol.

Value40

The cost per serving is high.
Cost per Natural-Form Therapeutic Serving
The cost per serving is high.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  4. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  5. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  6. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
    Loffredo L; Perri L; Di Castelnuovo A; Iacoviello L; De Gaetano G; Violi F · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016
    Meta-analysis16 studies pooledCardiovascular Support forVitamin E
  7. Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
    Chen B; Li Y; Li Z; Hu X; Zhen H; Chen H; Nie C; Hou Y; Zhu S; Xiao L; Li T · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2025
    Randomized trial90 participantsCardiovascular Support forVitamin E
  8. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
    Lonn E; Bosch J; Yusuf S; Sheridan P; Pogue J; Arnold JM; Ross C; Arnold A; Sleight P; Probstfield J; Dagenais GR; HOPE and HOPE-TOO Trial Investigators · JAMA · 2005
    Randomized trial9,541 participantsCardiovascular Support forVitamin E
  9. Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
    Liu Z; He Z; Xing Y · Journal of nutritional science · 2026
    Cohort study34,955 participantsCardiovascular Support forVitamin E
  10. Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
    Chin SF; Ibahim J; Makpol S; Abdul Hamid NA; Abdul Latiff A; Zakaria Z; Mazlan M; Mohd Yusof YA; Abdul Karim A; Wan Ngah WZ · Nutrition & metabolism · 2011
    Randomized trial62 participantsCardiovascular Support forVitamin E
  11. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  12. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  13. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  14. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  15. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  16. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  17. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  18. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Support forCoenzyme Q-10
  19. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  20. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsInflammation forCoenzyme Q-10