5-HTP 50 mg

5-HTP 50 mg

Jarrow Formulas4.6 (1,572 ratings)
Format:Capsule Quantity: 90 Veggie Cap(s) · 90 servings
Goals
$12.30 $0.13 per serving
Daily VitaLowest$12.30Amazon$14.99Daily Vita$15.99Vitacost$17.69Vitacost$18.99Pure Formulas$19.11iHerb$19.26

Product analysis

70 out of 100

5-HTP 50 mg is an economical, focused option for people considering 5-HTP for mood or sleep support.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Griffonia simplicifolia is named as the 5-HTP source, but its specific quality cannot be confirmed from the available information. The plant name alone does not establish how the preparation will perform.

Ingredient Transparency100

The 5-HTP amount and botanical source are disclosed. Those details make the serving straightforward to compare.

Value For Money85

The 5-HTP offers favorable value for the amount supplied. Its simple formula makes the cost comparison straightforward.

Customer Satisfaction81

Customer feedback is positive. A substantial review base adds context to satisfaction.

Product Focus62

One active ingredient keeps the formula focused on 5-HTP. Routine mood and sleep benefits remain uncertain, and the serving is below the reference amount used for its possible sleep role.

Format
Capsule
Container
90 Veggie Cap(s)
Per serving
$0.13
Customer rating
4.6 · 1,572 ratings
Report analysis

Goals

Sleep Support
Sleep Rhythm
Sleep Support
Impact
Moderate effect
B Ingredient FitD- PathwaysC- EvidenceA+ Formulation Logic
Study evidence
5-HTP Supportive 1 study
Mood Support
Mood Support
Impact
High effect
B Ingredient FitF PathwaysA EvidenceA+ Formulation Logic
5-HTP · 50 mg
Study evidence
5-HTP Supportive 9 studies
Stress Relief
Stress Relief
Impact
Moderate effect
B Ingredient FitF PathwaysC- EvidenceA+ Formulation Logic
Study evidence
5-HTP Supportive 18 studies

Ingredients

IngredientAmount per servingScore
5-HTP (Griffonia simplicifolia)
 50 mg 77
Gluten Free Adults 18–50 Vegan Vegetarian
Report overview
5-HTP (Griffonia simplicifolia) · 50 mg OverallScore77
B- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA- Value
Each serving provides 50 mg of 5-HTP. The cost per 100 mg of 5-HTP is relatively low. Griffonia simplicifolia is named as the source, but its 5-HTP standardization percentage is unknown. The label includes a warning about interactions with serotonin-modulating medication.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

Griffonia simplicifolia is named as the source, but its 5-HTP standardization percentage is unknown.
Botanical Source & Standardization
Griffonia simplicifolia is named as the source, but its 5-HTP standardization percentage is unknown.

Dose, Safety & Label Transparency79

Each serving provides 50 mg of 5-HTP. The label includes a warning about interactions with serotonin-modulating medication.
Dosage Potency & Range
Each serving provides 50 mg of 5-HTP.
Safety Warnings & Label Clarity
The label includes a warning about interactions with serotonin-modulating medication.

Value85

The cost per 100 mg of 5-HTP is relatively low.
Price per 100mg 5-HTP
The cost per 100 mg of 5-HTP is relatively low.
View ingredientView products
85 Performance

5-HTP 100 mg

NOW
Clearer botanical sourcing makes this a stronger quality alternative. Its 100 mg 5-HTP serving is more substantial than the original’s 50 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
83 Performance

5-HTP 100 mg Extra Strength

Swanson
A more focused formula and stronger disclosed ingredient profile make this a better quality choice. Its 100 mg 5-HTP serving is more substantial than the original’s 50 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
83 Performance

5-HTP Enhanced with Vitamins B6 and C

Doctor's Best
A more focused formula and stronger disclosed ingredient profile make this a better quality choice. Its 100 mg 5-HTP serving is more substantial than the original’s 50 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
84 Budget

5-HTP 50 mg

NOW
The lower recurring cost makes this a more economical eligible choice. Its 50 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
85 Budget

5-HTP 100 mg

Doctor's Best
The lower recurring cost makes this a more economical eligible choice. Its 100 mg 5-HTP serving is more substantial than the original’s 50 mg amount. The same serious interaction caution with serotonin-raising medicines applies.
82 Budget

5-HTP 50 mg

Swanson Premium Brand
The lower recurring cost makes this a more economical eligible choice. Its 50 mg 5-HTP serving matches the original amount while offering a different formula or package choice. The same serious interaction caution with serotonin-raising medicines applies.
83 Value

5-HTP 200mg

Best Naturals
Focused 5-HTP dosing and strong formula value make this a practical value alternative. A Griffonia source is identified, but active standardization remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
83 Value

5-HTP with Vitamin B6 & Vitamin C

Lake Avenue Nutrition
Focused 5-HTP dosing and strong formula value make this a practical value alternative. The active amount is disclosed, but botanical-source detail remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
82 Value

5-HTP 200 mg Maximum Strength

Swanson
Focused 5-HTP dosing and strong formula value make this a practical value alternative. A Griffonia source is identified, but active standardization remains incomplete. The same serious interaction caution with serotonin-raising medicines applies.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
    Jangid P; Malik P; Singh P; Sharma M; Gulia AK · Asian journal of psychiatry · 2013
    Randomized trial70 participantsMood Support for5-HTP
  2. The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
    Li S; Sutanto CN; Xia X; Kim JE · Nutrients · 2025
    Randomized trial30 participantsMood Support for5-HTP
  3. Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
    Javelle F; Lampit A; Bloch W; Häussermann P; Johnson SL; Zimmer P · Nutrition reviews · 2020
    Meta-analysis13 studies pooledMood Support for5-HTP
  4. Tryptophan and 5-hydroxytryptophan for depression.
    Shaw K; Turner J; Del Mar C · The Cochrane database of systematic reviews · 2002
    Systematic review64 participants2 studies pooledMood Support for5-HTP
  5. 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
    Aliño JJ; Gutierrez JL; Iglesias ML · International pharmacopsychiatry · 1976
    Non-randomized trial30 participantsMood Support for5-HTP
  6. The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
    Sutanto CN; Xia X; Heng CW; Tan YS; Lee DPS; Fam J; Kim JE · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trial30 participantsSleep Support for5-HTP
  7. Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
    Kahn RS; Westenberg HG; Verhoeven WM; Gispen-de Wied CC; Kamerbeek WD · International clinical psychopharmacology · 1987
    Randomized trial45 participantsStress Relief for5-HTP
  8. Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
    Schruers K; van Diest R; Overbeek T; Griez E · Psychiatry research · 2003
    Randomized trial48 participantsStress Relief for5-HTP
  9. Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
    Smarius LJ; Jacobs GE; Hoeberechts-Lefrandt DH; de Kam ML; van der Post JP; de Rijk R; van Pelt J; Schoemaker RC; Zitman FG; van Gerven JM; Gijsman HJ · Journal of psychopharmacology (Oxford, England) · 2008
    Randomized trialStress Relief for5-HTP
  10. Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
    Jacobs GE; Kamerling IM; de Kam ML; Derijk RH; van Pelt J; Zitman FG; van Gerven JM · Journal of psychopharmacology (Oxford, England) · 2010
    Randomized trialStress Relief for5-HTP
  11. An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress.
    Emanuele E; Bertona M; Minoretti P; Geroldi D · Neuro endocrinology letters · 2011
    Single-arm trial15 participantsStress Relief for5-HTP