$15.56 $0.34 per serving
Product analysis
5-HTP 100 mg Time Release may support sleep quality, with evidence limited mainly to older adults who already sleep poorly.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality40
The 5-HTP plant source and calcium form are identified. Their names do not establish a clear absorption advantage.
Ingredient Transparency100
Both amounts and sources are stated. That makes the serving straightforward to understand and compare.
Value For Money56
The 5-HTP contribution offers reasonable value at the full serving cost. Value for calcium remains uncertain.
Customer Satisfaction87
Customer feedback is very positive across a large number of ratings. That provides a broad satisfaction picture without proving mood or sleep effects.
Product Focus63
The clearest potential benefit is sleep quality in a narrow group of poor sleepers. Broader mood, stress and sustained weight-loss benefits remain uncertain.
- Format
Tablet - Container
- 45 Tablet(s)
- Per serving
- $0.34
- Also available
5-HTP 200 mg Time Release$13.80- Customer rating
- 4.6 · 8,364 ratings
Goals
Impact
Highest effect
5-HTP · 100 mg
5-HTP supplies a precursor for serotonin, but the mechanism alone does not establish improved mood. The supplied older-adult trial did not show a significant mood advantage over its control. Older findings in clinical depression do not establish routine benefit in generally healthy adults, even though the saved findings recognize the declared amount.
How this product is rated for Mood Support
Ingredient fit81
The relevant ingredients are recognized to different degrees according to their declared amounts and the formula's broader purpose.
Goal fit
Relevant mood ingredients sit within a broader formula containing ingredients aimed at other uses.
Dose adequacy
The declared amount fully matches the saved comparison range; this is not proof of an effective mood dose.
Pathways59
The saved findings describe potential routes of contribution, whose coverage does not itself demonstrate improved mood.
Depth
Monoamine signalling receives the greatest contribution in the saved findings; this does not establish a measured emotional benefit.
Breadth
The saved findings concentrate on one route, leaving other aspects of mood support limited.
Evidence94
The saved evidence contribution remains subject to the supplied population, outcome and preparation distinctions.
Evidence strength
5-HTP provides the leading evidence contribution in the saved findings, subject to the population and outcome limitations described above.
Studied preparation
The saved findings recognize the counted preparations, without establishing interchangeable extracts or routine mood benefit.
Formulation logic100
The counted ingredients meet partner requirements, with no configured conflict identified; amount limitations remain ingredient-specific.
Partner coverage
The counted ingredients have no unmet partner requirement in the supplied findings; this does not establish additional benefit from combining them.
Conflicts
No configured ingredient conflict is identified in the saved findings.
Effective doses
All counted ingredients clear the saved minimum amount threshold; that threshold is not a proven effective mood dose.
Impact
Moderate effect
5-HTP may support sleep quality in a narrow context, particularly among older adults who already sleep poorly, but it doesn't establish a general benefit. At 100 mg, the product matches the amount tied to that limited context, while its time-release form has no distinct sleep benefit established here.
Calcium is the only other listed active, and the supplied facts don't establish an independent sleep role for it. The possible contribution therefore centers on 5-HTP rather than sleep timing or relaxation.
How this product is rated for Sleep Support
Ingredient fit81
5-HTP is the sole sleep-related active; calcium is listed without a separate sleep role.
Goal fit
5-HTP provides the only sleep-related role; calcium does not add one in the supplied facts.
Dose adequacy
The 100 mg 5-HTP amount matches the limited context for possible sleep-quality support.
Pathways60
5-HTP connects to the pathway leading toward melatonin, without covering calming or sleep timing.
Depth
5-HTP relates to the pathway leading toward melatonin.
Breadth
The product has no separate calming or sleep-timing ingredient.
Evidence58
The product's possible sleep role is narrow and specific to poor sleepers, not a general benefit.
Evidence strength
5-HTP has limited, situation-specific sleep support rather than a general role.
Studied preparation
The active 5-HTP amount is disclosed, with no special preparation identified.
Formulation logic100
5-HTP can be used alone, and the listed ingredients show no identified bedtime conflict.
Partner coverage
5-HTP can contribute without a partner ingredient.
Conflicts
The listed ingredients have no identified bedtime conflict.
Effective doses
The listed 100 mg amount is the level tied to the limited sleep-quality context.
Impact
Moderate effect
Whether 5-HTP helps with everyday stress remains uncertain. It has some connection to anxiety and stress-related symptoms, but those benefits depend on the circumstances and don't translate reliably to general stress relief. The declared amount doesn't remove that uncertainty or tell you how much calmer you might feel.
How this product is rated for Stress Relief
Ingredient fit81
5-HTP has a conditional connection to anxiety; calcium doesn't add a clear stress-specific benefit here. The selected serving contains 100 mg 5-HTP, matching the upper comparison amount.
Goal fit
5-HTP has a conditional connection to anxiety; calcium doesn't add a clear stress-specific benefit here.
Dose adequacy
The selected serving contains 100 mg 5-HTP, matching the upper comparison amount.
Pathways46
The main connection is to mood-related processes, with a weaker link to sleep recovery.
Depth
The main connection is to mood-related processes, with a weaker link to sleep recovery.
Breadth
The ingredient connections are concentrated rather than covering every aspect of stress.
Evidence56
5-HTP's everyday stress benefit remains conditional and uncertain.
Evidence strength
5-HTP's everyday stress benefit remains conditional and uncertain.
Studied preparation
Griffonia-derived 5-HTP matches the relevant ingredient identity.
Formulation logic100
The relevant ingredients have no identified missing partner or particular ingredient conflict.
Partner coverage
The relevant ingredients can act alone or have their required partners present.
Conflicts
No particular ingredient conflict is identified.
Effective doses
The selected serving contains 100 mg 5-HTP, matching the upper comparison amount.
Impact
Moderate effect
5-HTP at 100 mg relates to appetite and fullness through its serotonin-precursor role. The supplied weight findings come from very small trials at much larger daily exposures, so the serving offers limited support for sustained weight loss. The time-release form has no supplied evidence of an extra weight-loss advantage.
How this product is rated for Weight Loss
Ingredient fit61
The relevant ingredients share the formula with ingredients directed at other goals. The assessed amounts provide a partial match to the saved comparisons.
Goal fit
The relevant ingredients share the formula with ingredients directed at other goals.
Dose adequacy
The assessed amounts provide a partial match to the saved comparisons.
Pathways9
The strongest saved connection is appetite and satiety, with limited coverage. None of the reviewed routes reaches the saved level for broad coverage.
Depth
The strongest saved connection is appetite and satiety, with limited coverage.
Breadth
None of the reviewed routes reaches the saved level for broad coverage.
Evidence62
5-HTP leads the saved evidence comparison at the assessed amount; this does not imply a large or sustained weight change. The assessed preparations match those recognized in the saved review.
Evidence strength
5-HTP leads the saved evidence comparison at the assessed amount; this does not imply a large or sustained weight change.
Studied preparation
The assessed preparations match those recognized in the saved review.
Formulation logic100
The assessed ingredients can work independently or have their relevant partner. No ingredient conflicts were recorded in the saved assessment. 1 of 1 assessed ingredients reach the saved amount threshold.
Partner coverage
The assessed ingredients can work independently or have their relevant partner.
Conflicts
No ingredient conflicts were recorded in the saved assessment.
Effective doses
1 of 1 assessed ingredients reach the saved amount threshold.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Calcium (Dibasic Calcium Phosphate) | 32 mg | |
5-HTP (Griffonia simplicifolia) | 100 mg |
5-HTP (Griffonia simplicifolia) · 100 mg OverallScore80
Each serving provides 100 mg of 5-HTP from Griffonia simplicifolia. The recorded warning mentions antidepressants or other serotonin-affecting medications.
How this ingredient is rated
Active Ingredient Quality & Bioavailability70
Griffonia simplicifolia is identified as the source, but the saved information does not specify a 5-HTP standardization percentage.
Botanical Source & Standardization
Griffonia simplicifolia is named; a percentage specifying 5-HTP standardization is not recorded.
Dose, Safety & Label Transparency100
The serving provides 100 mg of 5-HTP. The recorded warning mentions antidepressants or other serotonin-affecting medications.
Dosage Potency & Range
The serving contains 100 mg of 5-HTP.
Safety Warnings & Label Clarity
The recorded warning mentions antidepressants or other serotonin-affecting medications.
Value60
The whole-product serving costs about $0.35; its cost relative to the 5-HTP provided is moderate in the evaluation.
Price per 100mg 5-HTP
The whole-product price corresponds to about $0.35 per 100 mg of 5-HTP.
Alternative products
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
- Tryptophan and 5-hydroxytryptophan for depression.
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
- Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
- Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
- Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
- An open-label trial of L-5-hydroxytryptophan in subjects with romantic stress.
- The Effects of 5-HTP on Body Composition: An 8-Week Preliminary RCT.
- Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients.
- The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects.
- Serotonergic drugs : effects on appetite expression and use for the treatment of obesity.
- Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan.