Product Image

Vita Biotic 750 mg

Eclectic Herb
4.7
★ ★ ★ ★ ★
(144 ratings)
Vitamin B6 15 mg
Vitamin C 500 mg
Ginger
Product Image
Score64
Broad immune ingredients are undermined by duplicate and conflicting label entries plus a high preformed vitamin A amount.
How scoring works
Quantity:150 Capsule(s) • (50 servings)
Goals:
Immunity
General Health

Score 64

Broad immune ingredients are undermined by duplicate and conflicting label entries plus a high preformed vitamin A amount.
How scoring works
$41.44($0.82 per serving)
iHerb
$ 41.44
iHerb
$ 41.44
Vitacost
$ 41.44
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Analysis

Vitamin C, zinc, citrus bioflavonoids, echinacea, garlic, ginger, and cayenne create broad immune and antioxidant relevance. Several ingredients have meaningful listed weights, so the formula is not merely a trace-dose blend.

Duplicate echinacea entries and mismatched names for cayenne, garlic, and ginger undermine confidence in what the serving actually contains. Magnesium is too low to add much, while the preformed vitamin A amount is high enough to require careful stacking.

The three-capsule serving and complex botanical mix add interaction burden without dependable label clarity. A simpler formula with verified ingredient identities would be easier to use safely and assess for value.

Who is it for
  • Adults who have verified the current label with the manufacturer
  • Users specifically seeking a broad herbal immune blend
Best for
  • Short-term immune-focused use after label verification
  • Vitamin C and zinc support

Pros

  • Meaningful vitamin C and zinc amounts
  • Large citrus bioflavonoid amount
  • Includes multiple echinacea species

Cons

  • Conflicting ingredient and form names
  • Duplicate botanical entries
  • High preformed vitamin A amount

Warnings

  • The 3,000 mcg RAE preformed vitamin A amount should not be stacked with other retinol supplements, especially during pregnancy.
  • Garlic may increase bleeding tendency with anticoagulant or antiplatelet medicines.
  • Echinacea may conflict with immunosuppressant treatment.

Nutrient quality

59 Moderate impact

Several nutrients and botanicals plausibly support immune and antioxidant pathways. Aggressive preformed vitamin A and confusing duplicate botanical entries weaken safety and formulation confidence.

Ingredient transparency

67 High impact

Amounts are present and no proprietary blend hides the formula. Repeated echinacea and Oregon grape entries, mismatched plant names, and missing excipients seriously reduce clarity.

Customer satisfaction

67 High impact

The average rating is strong, with a moderate review count supporting the signal. No detailed reviews are supplied to assess recurring complaints or experiences tied to the intended use.

Value for money

61 Moderate impact

The formula contains several substantial immune-oriented actives and a useful supply. Label inconsistencies and an aggressive vitamin A amount reduce the value of that breadth.

Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A- Goal FitB+ Strength of SupportA CoverageB Formula Quality
Magnesium · 15 mgVitamin C · 500 mgZinc · 15 mgVitamin A · 3000 mcg RAE

Vitamin C, zinc gluconate, echinacea, citrus bioflavonoids, and several botanicals create strong direct immune coverage. Vitamin C and zinc meet useful immune-focused amounts.

Botanical extracts lack active-marker standardization, and duplicate ingredient listings make actual allocations harder to interpret. Preformed vitamin A reaches the adult upper intake level, creating a concern during pregnancy and when combined with other vitamin A supplements.

Study evidence
Vitamin A Supportive 107 studies
Vitamin C Supportive 53 studies
Zinc Supportive 73 studies
General Health
General Health
Impact
High effect
B- Goal FitC+ Strength of SupportB- CoverageC Formula Quality
Magnesium · 15 mgZinc · 15 mgVitamin C · 500 mg

Vitamin C, zinc, echinacea, garlic, bioflavonoids, and several botanicals provide broad immune-oriented support. The formula is more targeted than foundational, and inconsistent ingredient entries make its total botanical doses difficult to interpret.

Vitamin C and zinc have useful amounts, but the vitamin C form is omitted and several botanical standardization details are missing. Duplicate and inconsistent ingredient listings reduce confidence in a crowded formula. Preformed vitamin A reaches the adult daily upper limit, so pregnancy and use alongside other retinol-containing supplements warrant particular caution.

Study evidence
Vitamin C Supportive 56 studies
Zinc Supportive 60 studies
Skin Health
Skin Health
Impact
Moderate effect
C+ Goal FitC Strength of SupportB- CoverageD- Formula Quality
Zinc · 15 mgVitamin C · 500 mg

Vitamin C, zinc, and citrus bioflavonoids provide collagen, repair, and antioxidant support for skin. The stated amounts appear substantial.

Repeated botanical entries, inconsistent serving details, and an unspecified vitamin C form weaken label confidence. Preformed vitamin A reaches the adult upper intake level, creating concern in pregnancy and when combined with other vitamin A products.

Study evidence
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies
Zinc Supportive 66 studies
Vision Support
Macular and Blue Light Defense
Vision Support
Impact
Moderate effect
D- Goal FitC- Strength of SupportD CoverageC Formula Quality
Zinc · 15 mgVitamin C · 500 mgVitamin A · 3000 mcg RAE

Preformed vitamin A, vitamin C, and zinc provide basic visual-cycle and antioxidant support. The formula lacks lutein, zeaxanthin, vitamin E, copper, and DHA, so it is not a targeted eye product.

The amounts are clear, but the vitamin C form is unspecified and product serving details are inconsistent. The 3,000 mcg RAE preformed vitamin A amount reaches the adult upper limit, making pregnancy and stacking with other vitamin A products important concerns.

Study evidence
Vitamin A Supportive 65 studies
Vitamin C Disputed 24 studies
Zinc Supportive 39 studies
Anti-Inflammatory Support
Cellular Defense
Anti-Inflammatory Support
Impact
Moderate effect
C Goal FitD Strength of SupportC- CoverageF Formula Quality
Vitamin C · 500 mg

Vitamin C, citrus flavonoids, ginger, garlic, and zinc provide several antioxidant and immune-related mechanisms. Vitamin C is the most clearly meaningful contribution.

Ginger is modest, botanical standardization is absent, and duplicate ingredient entries make exposure difficult to interpret. Preformed vitamin A reaches the adult upper intake level and is a concern in pregnancy or when stacked with other vitamin A products.

Study evidence
Ginger Supportive 30 studies
Vitamin C Supportive 50 studies
Zinc Supportive 64 studies

Ingredients

IngredientAmount per serving
Vitamin A (Vitamin A Palmitate)
 3000 mcg RAE
Vitamin C
500 mg
Vitamin B6 (Pyridoxine Hydrochloride)
 15 mg
Magnesium (Magnesium Amino Acid Chelate)
 15 mg
Zinc (Zinc Gluconate)
 15 mg
Bioflavonoids (Citrus)
 500 mg
Echinacea (Echinacea angustifolia, Echinacea purpurea)
 455 mg
Garlic
195 mg
Oregon Grape
190 mg
Ginger
97 mg
Cayenne (Allium sativum)
 195 mg
Ginger (Capsicum annuum)
 65 mg
Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Vitamin B6 (Pyridoxine Hydrochloride) · 15 mg OverallScore70
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Pyridoxine hydrochloride is the sole disclosed B6 form and no riboflavin conversion support is listed. The 15 mg serving sits within the preferred range and below the chronic neuropathy ceiling. Value is good when the comprehensive active profile is considered.

View ingredientView products
Vitamin C · 500 mg OverallScore53
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

The disclosed vitamin C amount is useful, but its chemical form and buffering status are not identified. The capsule avoids listed sugars and artificial additives, yet inconsistent serving details and the unspecified form weaken label confidence. Preformed vitamin A reaches the adult upper intake level, creating a meaningful concern for pregnancy and for stacking with other vitamin A products.

View ingredientView products
Ginger · 97 mg OverallScore34
F Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

The disclosed ginger amount offers modest support but does not reach the preferred range. Missing active-marker and extraction details limit confidence in potency. Most of the serving cost supports other ingredients rather than a strong ginger dose.

View ingredientView products
Loading alternative details
78 Performance

Immune

NutraBio
<p>Chelated minerals, substantial N-acetylcysteine, yeast fermentate, and standardized botanicals create a clearer and more purposeful immune formula. The zinc amount is high enough to limit repeated unsupervised use, but ingredient quality and disclosure are stronger.</p>
71 Performance

Adrenal Assist

Vitanica
<p>Activated vitamin B6, chelated minerals, rhodiola, and several adaptogenic herbs provide broader stress, energy, and cognitive support alongside vitamin C. Immune alignment is less direct and the vitamin B6 amount is aggressive, but ingredient forms and functional breadth are stronger.</p>
65 Performance

ACF Extra Strength

Buried Treasure Liquid Nutrients
<p>Large vitamin C, zinc, elderberry, and echinacea amounts strengthen short-term immune-oriented coverage. The crowded unstandardized botanical stack and white willow create important uncertainty and interaction concerns.</p>
75 Budget

Stress B-Complex Caps

Twinlab
<p>A much lower serving cost supplies high vitamin C and broad B-vitamin coverage for general immune and stress support. Conventional forms and elevated pyridoxine make it less suitable for prolonged routine use, and it lacks the original's zinc and botanical breadth.</p>
79 Budget

Respir-All

NOW
<p>A lower serving cost provides a focused combination of quercetin, nettle, bromelain, buffered vitamin C, and a well-regarded zinc form. Vitamin B6 and licorice require care, but the formula avoids the original's aggressive preformed vitamin A and confusing duplicate botanicals.</p>
63 Budget

PreMense-T

LifeSeasons
<p>Vitamin B6, ginger, chaste berry, black cohosh, dong quai, and cramp bark make this the closest-cost remaining eligible option rather than a true lower-cost substitute. Its menstrual focus does not match the original's immune purpose, and duplicate botanicals plus bleeding and liver-related cautions narrow suitability.</p>
75 Value

Immufight Respiratory Support

Solaray
<p>Vitamin C, vitamin D, zinc, selenium, monolaurin, quercetin, and bromelain provide much broader immune coverage for a similar serving cost. Berberine and grapefruit extract add interaction concerns, but the formula gives more clearly differentiated active pathways.</p>
65 Value

Slow Flow

Vitanica
<p>Vitamin C, ginger, vitamin K, and several astringent herbs retain some antioxidant and botanical coverage for a moderate cost increase. The narrower flow-oriented purpose, duplicate yarrow entries, and unclear life root labeling limit value for someone mainly seeking immune support.</p>
75 Value

Migra-T

LifeSeasons
<p>Magnesium citrate, active B-vitamin forms, ginger, feverfew, willow bark, and coenzyme Q10 provide stronger form quality and more targeted support for a moderate cost increase. The headache-oriented formula is less relevant to immune support, while high vitamin B6, folate, and willow bark require careful suitability screening.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses.
    Xu K; Peng R; Zou Y; Jiang X; Sun Q; Song C · International journal of food sciences and nutrition · 2022
    Meta-analysis76 studies pooledGeneral Health forVitamin C
  2. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis.
    Bjelakovic G; Nikolova D; Gluud LL; Simonetti RG; Gluud C · JAMA · 2007
    Meta-analysis232,606 participants68 studies pooledGeneral Health forVitamin C
  3. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  4. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  5. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  6. The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.
    SeyedAlinaghi S; Shahidi R; Mojdeganlou H; Akhtaran FK; Maroufi SF; Maroufi SP; Mirzapour P; Karimi A; Khodaei S; Pour MM; Mehraeen E; Dadras O · Journal of health, population, and nutrition · 2024
    Systematic review28 studies pooledImmunity forVitamin C
  7. Efficacy and safety of steamed ginger extract for gastric health: a randomized, double-blind, placebo-controlled multi-center clinical trial.
    Baek HI; Ha NR; Kim C; Im TJ; Kim YY; Hwang SH; Bae JW · Food & function · 2025
    Randomized trial80 participantsGeneral Health forGinger
  8. A randomized, double-blind, placebo-controlled trial on the efficacy of ginger in the prevention of abdominal distention in post cesarean section patients.
    Tianthong W; Phupong V · Scientific reports · 2019
    Randomized trial178 participantsGeneral Health forGinger
  9. The efficacy of powdered ginger in osteoarthritis of the knee.
    Niempoog S; Pawa KK; Amatyakul C · Journal of the Medical Association of Thailand = Chotmaihet thangphaet · 2013
    Randomized trial60 participantsGeneral Health forGinger
  10. The effect of ginger supplementation on serum C-reactive protein, lipid profile and glycaemia: a systematic review and meta-analysis.
    Mazidi M; Gao HK; Rezaie P; Ferns GA · Food & nutrition research · 2022
    Meta-analysis9 studies pooledAnti-Inflammatory Support forGinger
  11. Ginger supplementation and metabolic health: an umbrella review of meta-analyses of randomized trials.
    Musazadeh V; Morvaridi M; Hosseini-Roknabadi SM; Mahmoudinezhad M; Jafari A; Shidfar F · Diabetology & metabolic syndrome · 2026
    Meta-analysis43,570 participants36 studies pooledAnti-Inflammatory Support forGinger
  12. Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial.
    Mozaffari-Khosravi H; Naderi Z; Dehghan A; Nadjarzadeh A; Fallah Huseini H · Journal of nutrition in gerontology and geriatrics · 2017
    Randomized trial120 participantsAnti-Inflammatory Support forGinger
  13. Effects of Ginger Supplementation on Markers of Inflammation and Functional Capacity in Individuals with Mild to Moderate Joint Pain.
    Broeckel J; Estes L; Leonard M; Dickerson BL; Gonzalez DE; Purpura M; Jäger R; Sowinski RJ; Rasmussen CJ; Kreider RB · Nutrients · 2025
    Randomized trial30 participantsAnti-Inflammatory Support forGinger
  14. The effect of ginger supplementation on some immunity and inflammation intermediate genes expression in patients with active Rheumatoid Arthritis.
    Aryaeian N; Shahram F; Mahmoudi M; Tavakoli H; Yousefi B; Arablou T; Jafari Karegar S · Gene · 2019
    Randomized trial70 participantsAnti-Inflammatory Support forGinger
  15. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  16. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  17. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  18. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  19. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  20. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
    Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
    Randomized trial40 participantsAnti-Inflammatory Support forZinc
  21. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
    Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
    Meta-analysis23 studies pooledAnti-Inflammatory Support forZinc
  22. The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
    Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Meta-analysis73 studies pooledAnti-Inflammatory Support forZinc
  23. The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
    Randomized trial46 participantsAnti-Inflammatory Support forZinc
  24. Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
    Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Meta-analysis75 studies pooledAnti-Inflammatory Support forZinc
  25. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  26. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  27. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  28. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  29. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  30. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  31. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  32. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  33. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  34. Depressed immune response to tetanus in children with vitamin A deficiency.
    Semba RD; Muhilal; Scott AL; Natadisastra G; Wirasasmita S; Mele L; Ridwan E; West KP; Sommer A · The Journal of nutrition · 1992
    Randomized trial236 participantsImmunity forVitamin A
  35. Impact of a single megadose of vitamin A at delivery on breastmilk of mothers and morbidity of their infants.
    Roy SK; Islam A; Molla A; Akramuzzaman SM; Jahan F; Fuchs G · European journal of clinical nutrition · 1997
    Randomized trial50 participantsImmunity forVitamin A
  36. Vitamin A supplementation reduces measles morbidity in young African children: a randomized, placebo-controlled, double-blind trial.
    Coutsoudis A; Broughton M; Coovadia HM · The American journal of clinical nutrition · 1991
    Randomized trial60 participantsImmunity forVitamin A
  37. Vitamin A supplementation enhances specific IgG antibody levels and total lymphocyte numbers while improving morbidity in measles.
    Coutsoudis A; Kiepiela P; Coovadia HM; Broughton M · The Pediatric infectious disease journal · 1992
    Randomized trial60 participantsImmunity forVitamin A
  38. Vitamin A supplementation reduces the monocyte chemoattractant protein-1 intestinal immune response of Mexican children.
    Long KZ; Santos JI; Estrada Garcia T; Haas M; Firestone M; Bhagwat J; Dupont HL; Hertzmark E; Rosado JL; Nanthakumar NN · The Journal of nutrition · 2006
    Randomized trial127 participantsImmunity forVitamin A
  39. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  40. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  41. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  42. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  43. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  44. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  45. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  46. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  47. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  48. Efficacy and Tolerability of Topical 0.1% Stabilized Bioactive Retinol for Photoaging: A Vehicle-Controlled Integrated Analysis.
    Farris P; Berson D; Bhatia N; Goldberg D; Lain E; Mariwalla K; Zeichner J; Miller D; McGuire T; Kizoulis M · Journal of drugs in dermatology : JDD · 2024
    Meta-analysis471 participants6 studies pooledSkin Health forVitamin A
  49. Tensile properties and contours of aging facial skin. A controlled double-blind comparative study of the effects of retinol, melibiose-lactose and their association.
    Piérard-Franchimont C; Castelli D; Cromphaut IV; Bertin C; Ries G; Cauwenbergh G; Piérard GE · Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2016
    Randomized trial120 participantsSkin Health forVitamin A
  50. Antiaging action of retinol: from molecular to clinical.
    Bellemère G; Stamatas GN; Bruère V; Bertin C; Issachar N; Oddos T · Skin pharmacology and physiology · 2009
    Randomized trial48 participantsSkin Health forVitamin A
  51. An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer.
    Balado-Simó P; Morgado-Carrasco D; Gómez-Armayones S; López-Ferrer A; Barco D; Ferrándiz-Pulido C; Podlipnik S · Journal of clinical medicine · 2025
    Narrative reviewSkin Health forVitamin A
  52. Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial.
    Chang H; Tao K; Yang Y; Wang Y; Ge M; Wang X; Tang S; Yu H · Journal of cosmetic dermatology · 2025
    Randomized trialSkin Health forVitamin A
  53. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  54. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  55. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  56. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  57. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  58. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  59. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  60. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  61. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  62. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  63. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa.
    Berson EL; Rosner B; Sandberg MA; Hayes KC; Nicholson BW; Weigel-DiFranco C; Willett W · Archives of ophthalmology (Chicago, Ill. : 1960) · 1993
    Randomized trial601 participantsVision Support forVitamin A
  64. Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial.
    Toshida H; Funaki T; Ono K; Tabuchi N; Watanabe S; Seki T; Otake H; Kato T; Ebihara N; Murakami A · Drug design, development and therapy · 2018
    Randomized trial66 participantsVision Support forVitamin A
  65. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age.
    Imdad A; Mayo-Wilson E; Haykal MR; Regan A; Sidhu J; Smith A; Bhutta ZA · The Cochrane database of systematic reviews · 2022
    Meta-analysis1,223,856 participants47 studies pooledVision Support forVitamin A
  66. Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity.
    Mactier H; McCulloch DL; Hamilton R; Galloway P; Bradnam MS; Young D; Lavy T; Farrell L; Weaver LT · The Journal of pediatrics · 2012
    Randomized trial89 participantsVision Support forVitamin A
  67. Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy.
    Owsley C; McGwin G; Jackson GR; Heimburger DC; Piyathilake CJ; Klein R; White MF; Kallies K · Investigative ophthalmology & visual science · 2006
    Randomized trial104 participantsVision Support forVitamin A
  68. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  69. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  70. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  71. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  72. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C
  73. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  74. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  75. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  76. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  77. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc