Product Image

SynaQuell

Thorne
4.7
★ ★ ★ ★ ★
(167 ratings)
Niacin 207.5 mg
Curcumin 125 mg
Valine 625 mg
Isoleucine 625 mg
Resveratrol 125 mg
Glutathione 250 mg
Coenzyme Q-10 50 mg
Product Image
Score75
High-quality delivery systems and a broad antioxidant core stand out, but modest secondary doses and premium positioning reduce practical value.
How scoring works
Quantity:8 Ounce(s) • (30 servings)
Goals:
Anti-Inflammatory Support
Metabolism Boost

Score 75

High-quality delivery systems and a broad antioxidant core stand out, but modest secondary doses and premium positioning reduce practical value.
How scoring works
$75.00($2.50 per serving)
Pure Formulas
$ 75.00
iHerb
$ 0.00
Amazon
$ 75.00
Report prices

Analysis

Meriva curcumin phytosome, reduced glutathione, trans-resveratrol, and a CoQ10 phytosome give the powder strong multi-pathway antioxidant and inflammatory-balance relevance. The curcumin delivery system and reduced glutathione are meaningful strengths, while the exact active curcuminoid yield and underlying CoQ10 form are not stated.

Nicotinamide riboside, riboflavin 5-phosphate, branched-chain amino acids, betaine, and beta-hydroxybutyrate broaden the design toward cellular energy and recovery. Most of these additions are supportive rather than decisive because their amounts are below those commonly chosen for focused standalone use.

The formula is best suited to someone who specifically wants one complex powder rather than separate antioxidant and metabolic supplements. DHA is too low for dedicated omega-3 support, and the blend has little direct collagen, hydration, or barrier support despite some skin-relevant antioxidants.

Who is it for
  • Adults seeking a premium multi-pathway antioxidant powder
  • People who want curcumin, glutathione, resveratrol, and CoQ10 in one serving
  • Users prioritizing cellular-energy and recovery support over a single high-dose active
Best for
  • Broad antioxidant and inflammatory-balance support
  • Combining mitochondrial cofactors with recovery-oriented amino acids
  • Users who value phytosome delivery systems

Pros

  • Uses Meriva curcumin phytosome for improved delivery
  • Provides 250 mg reduced glutathione
  • Combines trans-resveratrol with a CoQ10 phytosome
  • Includes active riboflavin 5-phosphate
  • Discloses individual ingredient amounts

Cons

  • DHA is too low for focused omega-3 support
  • Nicotinamide riboside and CoQ10 are modest for standalone goals
  • Curcuminoid yield and the underlying CoQ10 molecular form are not stated
  • The complex formula makes poor value for users seeking only one of its actives
  • Skin support is indirect and lacks collagen or barrier-focused ingredients

Warnings

  • Curcumin, resveratrol, and DHA may add to bleeding tendency with anticoagulant or antiplatelet medicines and around surgery.
  • Curcumin can aggravate symptoms in people with gallstones or bile-duct obstruction because it can stimulate bile flow.
  • The leucine, isoleucine, and valine content is unsuitable for people with maple syrup urine disease or another diagnosed branched-chain amino-acid metabolism disorder.

Nutrient quality

86 Highest impact

Riboflavin phosphate, reduced glutathione, curcumin phytosome, algal DHA, and coenzyme Q10 phytosome are well-regarded forms. Branched-chain amino acids and several antioxidants are meaningful, while curcumin, DHA, coenzyme Q10, and betaine are moderate or low.

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Ingredient transparency

78 High impact

Principal actives have stated amounts, though separate form entries display no usable quantities. A complete excipient and flavoring list is not available in the supplied data.

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Customer satisfaction

71 High impact

The average rating is very strong. The rating volume is adequate for a useful satisfaction signal.

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Value for money

60 Moderate impact

The premium serving cost is difficult to justify for several moderate-dose actives. Most additions are purposeful rather than low-value padding.

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Report analysis

Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
A- Goal FitB Strength of SupportA- CoverageA- Formula Quality
Coenzyme Q-10 · 50 mgGlutathione · 250 mgCurcumin · 125 mg

Meriva curcumin phytosome, reduced glutathione, trans-resveratrol, and phytosome CoQ10 create a strong multi-pathway anti-inflammatory formula. Curcumin and glutathione reach meaningful amounts, while resveratrol and CoQ10 add supportive antioxidant coverage.

Advanced phytosome delivery improves the curcumin and CoQ10 case, though active curcuminoid yield and the underlying CoQ10 form are not stated. The 125 mg DHA amount is too low to provide meaningful marine omega-3 inflammation-resolution support.

Study evidence
Coenzyme Q-10 Supportive 46 studies
Curcumin Supportive 68 studies
Glutathione Disputed 2 studies
Resveratrol Supportive 34 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
C Goal FitB- Strength of SupportC CoverageB+ Formula Quality
Niacin · 207.5 mgRiboflavin · 25 mgMagnesium · 59 mgResveratrol · 125 mgCurcumin · 125 mgCoenzyme Q-10 · 50 mg

Nicotinamide riboside, resveratrol, CoQ10, riboflavin, and ketone-related minerals form a coherent mitochondrial-energy formula. Human evidence supports effects on cellular markers more clearly than a reliable increase in metabolic rate or fat loss.

Named forms and individual doses make the main actives easy to assess. The amounts provide moderate mitochondrial depth, but no caffeine, green tea, chromium, or strong thyroid support broadens the effect.

Study evidence
Coenzyme Q-10 Disputed 11 studies
Niacin Supportive 17 studies
Resveratrol Supportive 21 studies
Riboflavin Mixed 5 studies

Ingredients

IngredientAmount per serving
Calories
23 Calorie(s)
Total Carbohydrates
1 Gram(s)
Riboflavin
25 mg
Magnesium
59 mg
L-Leucine
1.25 Gram(s)
L-Isoleucine
625 mg
L-Valine
625 mg
Beta Hydroxybutyrate
500 mg
Glutathione, Reduced
250 mg
Nicotinamide Riboside Hydrogen Malate
207.5 mg
Meriva
125 mg
Docosahexaenoic Acid
125 mg
Trans-Resveratrol
125 mg
Ubiqsome
50 mg
Betaine Anhydrous
42.5 mg
Gluten Free Adults 18–50 Women
Report overview
Niacin · 207.5 mg OverallScore72
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyF Value

Nicotinamide riboside is a direct NAD+ precursor that aligns well with cellular-energy use. The 207.5 mg amount falls below the preferred effective range, and no patented or independently verified source is identified. A complex powder format adds other premium actives, but the cost per NR serving remains weak.

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Curcumin · 125 mg OverallScore71
A Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyF Value

Meriva supplies a clinically validated phytosome delivery system with better absorption than a standard extract. Its listed amount sits within the target range for patented bioavailable forms, although the active curcuminoid yield and third-party testing status are missing. Curcumin value is weak at the very high serving cost, while amino acids, glutathione, DHA, resveratrol, and other actives broaden the formula.

View ingredientView products
Valine · 625 mg OverallScore60
B- Active Ingredient Quality & BioavailabilityB- Dose, Safety & Label TransparencyF Value

Free-form L-valine is clearly disclosed, but the 625 mg serving is well below the collection benchmark. The standard powder format is practical for mixing, though no micronization or sport-specific certification is stated. The cost per gram is high, which limits value for someone focused mainly on valine.

View ingredientView products

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Anti-Inflammatory Efficacy of Curcumin as an Adjunct to Non-Surgical Periodontal Treatment: A Systematic Review and Meta-Analysis.
    Zhang Y; Huang L; Zhang J; De Souza Rastelli AN; Yang J; Deng D · Frontiers in pharmacology · 2024
    Meta-analysis846 participants18 studies pooledAnti-Inflammatory Support forCurcumin
  2. Can resveratrol supplement change inflammatory mediators? A systematic review and meta-analysis on randomized clinical trials.
    Haghighatdoost F; Hariri M · European journal of clinical nutrition · 2020
    Meta-analysis658 participants15 studies pooledAnti-Inflammatory Support forResveratrol
  3. Curcumin and/or omega-3 polyunsaturated fatty acids supplementation reduces insulin resistance and blood lipids in individuals with high risk of type 2 diabetes: a randomised controlled trial.
    Thota RN; Acharya SH; Garg ML · Lipids in health and disease · 2019
    Randomized trial64 participantsMetabolism Boost forCurcumin
  4. Effect of Coenzyme Q10 Supplementation on Serum of High Sensitivity c-reactive Protein Level in Patients with Cardiovascular Diseases: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
    Aslani Z; Shab-Bidar S; Fatahi S; Djafarian K · International journal of preventive medicine · 2022
    Meta-analysis302 participants5 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  5. Effects of NAD+ precursor supplementation on glucose and lipid metabolism in humans: a meta-analysis.
    Zhong O; Wang J; Tan Y; Lei X; Tang Z · Nutrition & metabolism · 2022
    Meta-analysis14,750 participants40 studies pooledMetabolism Boost forNiacin
  6. Coenzyme Q10 does not improve peripheral insulin sensitivity in statin-treated men and women: the LIFESTAT study.
    Kuhlman AB; Morville T; Dohlmann TL; Hansen M; Kelly B; Helge JW; Dela F · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2019
    Randomized trial35 participantsMetabolism Boost forCoenzyme Q-10
  7. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsAnti-Inflammatory Support forGlutathione
  8. Riboflavin and riboflavin-derived cofactors in adolescent girls with anorexia nervosa.
    Capo-chichi CD; Guéant JL; Lefebvre E; Bennani N; Lorentz E; Vidailhet C; Vidailhet M · The American journal of clinical nutrition · 1999
    Clinical trial34 participantsMetabolism Boost forRiboflavin
  9. Oral turmeric/curcumin effects on inflammatory markers in chronic inflammatory diseases: A systematic review and meta-analysis of randomized controlled trials.
    White CM; Pasupuleti V; Roman YM; Li Y; Hernandez AV · Pharmacological research · 2020
    Meta-analysis1,344 participants19 studies pooledAnti-Inflammatory Support forCurcumin
  10. Coenzyme Q10 supplementation in burn patients: a double-blind placebo-controlled randomized clinical trial.
    Kiani Z; Khorsand N; Beigi F; Askari G; Sharma M; Bagherniya M · Trials · 2024
    Randomized trial60 participantsAnti-Inflammatory Support forCoenzyme Q-10
  11. No Beneficial Effects of Resveratrol on the Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial.
    Kjær TN; Ornstrup MJ; Poulsen MM; Stødkilde-Jørgensen H; Jessen N; Jørgensen JOL; Richelsen B; Pedersen SB · The Journal of clinical endocrinology and metabolism · 2017
    Randomized trial74 participantsAnti-Inflammatory Support forResveratrol
  12. Inhibition of Intracellular Triglyceride Lipolysis Suppresses Cold-Induced Brown Adipose Tissue Metabolism and Increases Shivering in Humans.
    Blondin DP; Frisch F; Phoenix S; Guérin B; Turcotte ÉE; Haman F; Richard D; Carpentier AC · Cell metabolism · 2017
    Clinical trialMetabolism Boost forNiacin
  13. Curcumin extract improves beta cell functions in obese patients with type 2 diabetes: a randomized controlled trial.
    Yaikwawong M; Jansarikit L; Jirawatnotai S; Chuengsamarn S · Nutrition journal · 2024
    Randomized trial272 participantsMetabolism Boost forCurcumin
  14. Coenzyme Q10 supplementation raises plasma levels without improving mitochondrial function in older adults.
    Schmücker M; Tranberg C; Borch J; Kaae MK; Damgaard M; Flensted-Jensen M; Blom I; Morosetti M; Barbarossa S; Orlando P; Tiano L; Dela F; Helge JW; Larsen S · GeroScience · 2026
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10
  15. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsAnti-Inflammatory Support forGlutathione
  16. Disorders of flavin adenine dinucleotide metabolism: MADD and related deficiencies.
    Mereis M; Wanders RJA; Schoonen M; Dercksen M; Smuts I; van der Westhuizen FH · The international journal of biochemistry & cell biology · 2024
    Systematic reviewMetabolism Boost forRiboflavin
  17. Reverse cholesterol transport and lipid peroxidation biomarkers in major depression and bipolar disorder: A systematic review and meta-analysis.
    Almulla AF; Thipakorn Y; Algon AAA; Tunvirachaisakul C; Al-Hakeim HK; Maes M · Brain, behavior, and immunity · 2023
    Meta-analysis34,051 participants176 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  18. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial.
    Huhn S; Beyer F; Zhang R; Lampe L; Grothe J; Kratzsch J; Willenberg A; Breitfeld J; Kovacs P; Stumvoll M; Trampel R; Bazin PL; Villringer A; Witte AV · NeuroImage · 2019
    Randomized trial60 participantsAnti-Inflammatory Support forResveratrol
  19. Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial.
    Jazayeri-Tehrani SA; Rezayat SM; Mansouri S; Qorbani M; Alavian SM; Daneshi-Maskooni M; Hosseinzadeh-Attar MJ · Nutrition & metabolism · 2024
    Randomized trial84 participantsAnti-Inflammatory Support forCurcumin
  20. Effects of phytosomal curcumin on anthropometric parameters, insulin resistance, cortisolemia and non-alcoholic fatty liver disease indices: a double-blind, placebo-controlled clinical trial.
    Cicero AFG; Sahebkar A; Fogacci F; Bove M; Giovannini M; Borghi C · European journal of nutrition · 2021
    Randomized trial80 participantsMetabolism Boost forCurcumin
  21. Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and systematic review.
    Zhang Y; He Y; Ma M; Dong H; Ma Z · The Journal of international medical research · 2026
    Meta-analysis433 participants14 studies pooledMetabolism Boost forCoenzyme Q-10
  22. Changes in glucose metabolism, C-reactive protein, and liver enzymes following intake of NAD + precursor supplementation: a systematic review and meta-regression analysis.
    Sohouli MH; Tavakoli S; Reis MG; Hekmatdoost A; Guimarães NS · Nutrition & metabolism · 2024
    Meta-analysis9,256 participants45 studies pooledMetabolism Boost forNiacin
  23. Anaemia during pregnancy: could riboflavin deficiency be implicated?
    Duffy B; McNulty H; Ward M; Pentieva K · The Proceedings of the Nutrition Society · 2026
    Narrative reviewMetabolism Boost forRiboflavin
  24. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  25. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  26. Are curcuminoids effective C-reactive protein-lowering agents in clinical practice? Evidence from a meta-analysis.
    Sahebkar A · Phytotherapy research : PTR · 2014
    Meta-analysis342 participants6 studies pooledAnti-Inflammatory Support forCurcumin
  27. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design.
    Karandish M; Mozaffari-Khosravi H; Mohammadi SM; Cheraghian B; Azhdari M · Phytotherapy research : PTR · 2021
    Randomized trial84 participantsMetabolism Boost forCurcumin
  28. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial.
    Zhang P; Chen K; He T; Guo H; Chen X · Nutrition & metabolism · 2022
    Randomized trial101 participantsMetabolism Boost forCoenzyme Q-10
  29. Targeted Microbiome Intervention by Microencapsulated Delayed-Release Niacin Beneficially Affects Insulin Sensitivity in Humans.
    Fangmann D; Theismann EM; Türk K; Schulte DM; Relling I; Hartmann K; Keppler JK; Knipp JR; Rehman A; Heinsen FA; Franke A; Lenk L; Freitag-Wolf S; Appel E; Gorb S; Brenner C; Seegert D; Waetzig GH; Rosenstiel P; Schreiber S; Schwarz K; Laudes M · Diabetes care · 2018
    Clinical trialMetabolism Boost forNiacin
  30. Effect of curcumin on inflammatory markers and disease activity in patients with rheumatoid arthritis: A meta-analysis.
    Zhang F; Niu B · Medicine · 2025
    Meta-analysis7 studies pooledAnti-Inflammatory Support forCurcumin
  31. Effects of coenzyme Q10 supplementation on inflammation, angiogenesis, and oxidative stress in breast cancer patients: a systematic review and meta-analysis of randomized controlled- trials.
    Alimohammadi M; Rahimi A; Faramarzi F; Golpour M; Jafari-Shakib R; Alizadeh-Navaei R; Rafiei A · Inflammopharmacology · 2021
    Meta-analysis5 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  32. Efficacy and safety of Rhizoma curcumea longae with respect to improving the glucose metabolism of patients at risk for cardiovascular disease: a meta-analysis of randomised controlled trials.
    Huang J; Qin S; Huang L; Tang Y; Ren H; Hu H · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2020
    Meta-analysis1,277 participants14 studies pooledMetabolism Boost forCurcumin
  33. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsAnti-Inflammatory Support forResveratrol
  34. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forCoenzyme Q-10
  35. The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans.
    Christen S; Redeuil K; Goulet L; Giner MP; Breton I; Rota R; Frézal A; Nazari A; Van den Abbeele P; Godin JP; Nutten S; Cuenoud B · Nature metabolism · 2026
    Randomized trial65 participantsMetabolism Boost forNiacin
  36. Effect of curcumin on C-reactive protein as a biomarker of systemic inflammation: An updated meta-analysis of randomized controlled trials.
    Gorabi AM; Abbasifard M; Imani D; Aslani S; Razi B; Alizadeh S; Bagheri-Hosseinabadi Z; Sathyapalan T; Sahebkar A · Phytotherapy research : PTR · 2022
    Meta-analysis32 studies pooledAnti-Inflammatory Support forCurcumin
  37. The effects of curcumin intake on wound healing and metabolic status in patients with diabetic foot ulcer: A randomized, double-blind, placebo-controlled trial.
    Mokhtari M; Razzaghi R; Momen-Heravi M · Phytotherapy research : PTR · 2021
    Randomized trial60 participantsMetabolism Boost forCurcumin
  38. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsAnti-Inflammatory Support forResveratrol
  39. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsAnti-Inflammatory Support forCoenzyme Q-10
  40. Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise.
    Diaz-Castro J; Mira-Rufino PJ; Moreno-Fernandez J; Chirosa I; Chirosa JL; Guisado R; Ochoa JJ · Food & function · 2021
    Randomized trial100 participantsMetabolism Boost forCoenzyme Q-10
  41. Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy.
    Fraterrigo G; Fabbrini E; Mittendorfer B; O'Rahilly S; Scherer PE; Patterson BW; Klein S · Cardiorenal medicine · 2021
    Single-arm trial9 participantsMetabolism Boost forNiacin
  42. Curcumin Nanomicelle Improves Lipid Profile, Stress Oxidative Factors and Inflammatory Markers in Patients Undergoing Coronary Elective Angioplasty; A Randomized Clinical Trial.
    Helli B; Gerami H; Kavianpour M; Heybar H; Hosseini SK; Haghighian HK · Endocrine, metabolic & immune disorders drug targets · 2022
    Randomized trial90 participantsAnti-Inflammatory Support forCurcumin
  43. Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.
    Fan L; Feng Y; Chen GC; Qin LQ; Fu CL; Chen LH · Pharmacological research · 2017
    Meta-analysis17 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  44. Effects of metformin and curcumin in women with polycystic ovary syndrome: A factorial clinical trial.
    Feghhi F; Ghaznavi H; Sheervalilou R; Razavi M; Sepidarkish M · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2024
    Randomized trial200 participantsMetabolism Boost forCurcumin
  45. Resveratrol Supplementation Reduces Pain and Inflammation in Knee Osteoarthritis Patients Treated with Meloxicam: A Randomized Placebo-Controlled Study.
    Marouf BH; Hussain SA; Ali ZS; Ahmmad RS · Journal of medicinal food · 2024
    Randomized trial110 participantsAnti-Inflammatory Support forResveratrol
  46. The effect of 8 weeks of physical training on muscle performance and maximal fat oxidation rates in patients treated with simvastatin and coenzyme Q10 supplementation.
    Kuhlman AB; Mikkelsen LB; Regnersgaard S; Heinrichsen S; Nielsen FH; Frandsen J; Orlando P; Silvestri S; Larsen S; Helge JW; Dela F · The Journal of physiology · 2022
    Randomized trial26 participantsMetabolism Boost forCoenzyme Q-10
  47. Effects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose tolerance.
    Linke A; Sonnabend M; Fasshauer M; Höllriegel R; Schuler G; Niebauer J; Stumvoll M; Blüher M · Atherosclerosis · 2009
    Randomized trial30 participantsMetabolism Boost forNiacin
  48. Effect of curcumin on circulating interleukin-6 concentrations: A systematic review and meta-analysis of randomized controlled trials.
    Derosa G; Maffioli P; Simental-Mendía LE; Bo S; Sahebkar A · Pharmacological research · 2018
    Meta-analysis9 studies pooledAnti-Inflammatory Support forCurcumin
  49. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsAnti-Inflammatory Support forCoenzyme Q-10
  50. The efficacy of resveratrol supplementation on inflammation and oxidative stress in type-2 diabetes mellitus patients: randomized double-blind placebo meta-analysis.
    Zhu P; Jin Y; Sun J; Zhou X · Frontiers in endocrinology · 2025
    Meta-analysis533 participants6 studies pooledAnti-Inflammatory Support forResveratrol
  51. Effect of Curcumin on Glycaemic and Lipid Parameters in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Simental-Mendía LE; Shah N; Sathyapalan T; Majeed M; Orekhov AN; Jamialahmadi T; Sahebkar A · Reproductive sciences (Thousand Oaks, Calif.) · 2022
    Meta-analysis5 studies pooledMetabolism Boost forCurcumin
  52. The effect of coenzyme Q10 intake on metabolic profiles in women candidates for in-vitro fertilization: a randomised trial.
    Ahmadi Asouri S; Asemi R; Aghadavod E; Jamilian M · Annals of medicine and surgery (2012) · 2024
    Randomized trial40 participantsMetabolism Boost forCoenzyme Q-10
  53. Lipid-lowering therapies, glucose control and incident diabetes: evidence, mechanisms and clinical implications.
    Zafrir B; Jain M · Cardiovascular drugs and therapy · 2015
    Narrative reviewMetabolism Boost forNiacin
  54. The effects of nanocurcumin supplementation on inflammation in hemodialysis patients: A randomized controlled trial.
    Vafadar-Afshar G; Rasmi Y; Yaghmaei P; Khadem-Ansari MH; Makhdoomi K; Rasouli J · Hemodialysis international. International Symposium on Home Hemodialysis · 2021
    Randomized trial54 participantsAnti-Inflammatory Support forCurcumin
  55. Coenzyme Q10 supplementation ameliorates inflammatory markers in patients with multiple sclerosis: a double blind, placebo, controlled randomized clinical trial.
    Sanoobar M; Eghtesadi S; Azimi A; Khalili M; Khodadadi B; Jazayeri S; Gohari MR; Aryaeian N · Nutritional neuroscience · 2015
    Randomized trial48 participantsAnti-Inflammatory Support forCoenzyme Q-10
  56. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledAnti-Inflammatory Support forResveratrol
  57. Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurChexia).
    Thambamroong T; Seetalarom K; Saichaemchan S; Pumsutas Y; Prasongsook N · Journal of nutrition and metabolism · 2024
    Randomized trial20 participantsMetabolism Boost forCurcumin
  58. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledMetabolism Boost forCoenzyme Q-10
  59. Differences in metabolism of time-release and unmodified nicotinic acid: explanation of the differences in hypolipidemic action?
    Stern RH; Freeman D; Spence JD · Metabolism: clinical and experimental · 1992
    Clinical trial10 participantsMetabolism Boost forNiacin
  60. The effects of curcumin supplementation on biomarkers of inflammation, oxidative stress, and endothelial function: A meta-analysis of meta-analyses.
    Kavyani Z; Najafi K; Naghsh N; Karvane HB; Musazadeh V · Prostaglandins & other lipid mediators · 2024
    Meta-analysis21 studies pooledAnti-Inflammatory Support forCurcumin
  61. A Pilot Trial of Nicotinamide Riboside and Coenzyme Q10 on Inflammation and Oxidative Stress in CKD.
    Ahmadi A; Valencia AP; Begue G; Norman JE; Fan S; Durbin-Johnson BP; Jenner BN; Campbell MD; Reyes G; Kapahi P; Himmelfarb J; de Boer IH; Marcinek DJ; Kestenbaum BR; Gamboa JL; Roshanravan B · Clinical journal of the American Society of Nephrology : CJASN · 2026
    Randomized trial25 participantsAnti-Inflammatory Support forCoenzyme Q-10
  62. Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized, double-blind, placebo-controlled, cross-over trial.
    Bo S; Ciccone G; Castiglione A; Gambino R; De Michieli F; Villois P; Durazzo M; Cavallo-Perin P; Cassader M · Current medicinal chemistry · 2013
    Randomized trial50 participantsAnti-Inflammatory Support forResveratrol
  63. Impact of exercise intervention with or without curcumin supplementation on body fat composition, glucose, and lipid metabolism in obese adults: A meta-analysis.
    Li Y; Guo L; Zhang D; Ma J · Lipids · 2025
    Meta-analysis183 participants7 studies pooledMetabolism Boost forCurcumin
  64. Clinical applications of coenzyme Q10.
    Garrido-Maraver J; Cordero MD; Oropesa-Avila M; Vega AF; de la Mata M; Pavon AD; Alcocer-Gomez E; Calero CP; Paz MV; Alanis M; de Lavera I; Cotan D; Sanchez-Alcazar JA · Frontiers in bioscience (Landmark edition) · 2014
    Narrative reviewMetabolism Boost forCoenzyme Q-10
  65. [Niacin in therapy].
    Nagalski A; Bryła J · Postepy higieny i medycyny doswiadczalnej (Online) · 2007
    Narrative reviewMetabolism Boost forNiacin
  66. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledAnti-Inflammatory Support forCoenzyme Q-10
  67. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
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