Pyridoxal 5'-Phosphate
Thorne
Pyridoxal 5'-Phosphate
4.8
★ ★ ★ ★ ★
(1172 ratings)
Vitamin B6 33.8 mg
Score 100
The gold standard for B6 supplementation, offering the highly active and bioavailable P-5-P form for superior efficacy and safety.
Quantity: 180 Capsule(s) • (180 servings)
Goals: flag Detoxification flag Mood Support flag Bone Health flag Brain Health flag Mental Focus
leaderboard Score 100
The gold standard for B6 supplementation, offering the highly active and bioavailable P-5-P form for superior efficacy and safety.
insights Analysis
Thorne Pyridoxal 5'-Phosphate provides 33.8mg of Vitamin B6 exclusively as Pyridoxal 5-Phosphate (P-5-P). This is the gold standard for B6 supplementation because it is the metabolically active form, meaning it can be immediately utilized by the body without requiring conversion in the liver. This direct bioavailability minimizes the risk of toxicity (like peripheral neuropathy) that can occur with high doses of the less active pyridoxine hydrochloride form. The dosage is therapeutically effective for a wide range of needs related to energy, brain health, and mood support, and Thorne is a highly respected brand known for its purity and scientific backing. Its higher price per serving is justified by the superior form and brand quality, offering excellent long-term value for health.
- Contains Pyridoxal 5-Phosphate (P-5-P), the active coenzyme form of B6, for superior bioavailability and efficacy.
- Significantly lower risk of peripheral neuropathy compared to pyridoxine hydrochloride, even at higher doses.
- Therapeutically effective dosage (33.8mg) for comprehensive B6 support.
- Produced by Thorne, a highly reputable brand known for quality and purity.
- Higher price per serving compared to basic pyridoxine HCl B6 supplements, though justified by quality.
$47.70($0.26 per serving)
 iHerb | $ 47.70 | |
 Pure Formulas | $ 53.00 | |
 Amazon | $ 53.00 |
Ingredients
| Ingredient | Amount per serving |
|---|---|
Vitamin B6 | 33.8 mg |
Categories
Vitamin B6 100
This product represents the best in the Vitamin B6 collection by exclusively offering the active Pyridoxal 5-Phosphate (P-5-P) form. This ensures superior bioavailability, efficacy, and safety compared to other B6 products, making it the top choice for anyone seeking high-quality B6 supplementation.
Goals
P-5-P is directly involved as a cofactor in numerous enzymatic reactions related to energy metabolism, including the breakdown of carbohydrates, fats, and proteins. Its active form ensures maximal utilization by the body, providing highly efficient support for cellular energy production.
As the active form, P-5-P is critical for the synthesis of major neurotransmitters like serotonin, dopamine, and GABA, which are essential for mood, cognition, and nerve function. Its direct bioavailability ensures optimal support for brain health without the risks associated with inactive forms.
P-5-P plays a direct and vital role in the metabolic pathways that produce mood-regulating neurotransmitters. By providing the active form, this supplement optimally supports emotional balance and reduces symptoms associated with B6 deficiency, making it exceptionally effective for mood.
93 Value 
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
Offers a pure P-5-P supplement at a significantly lower price point, providing excellent value for the active form of B6.
95 Value 
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
Contains the active P-5-P form of B6 at a substantially lower price per serving, representing outstanding value for high-quality B6.
98 Value 
P-5-P/Mag
Terry Naturally
4.8
★★★★★
(2668 ratings)
Combines the active P-5-P B6 with beneficial minerals at a lower price per serving, offering an excellent synergistic blend at a competitive cost.
87 Performance 
B-Complex '100'
Solgar
4.7
★★★★★
(446 ratings)
For comprehensive B vitamin support, this product offers a full spectrum of B vitamins that work synergistically for energy, brain, and general health, which may be preferred over isolated P-5-P.
86 Performance 
Super Stress B-Complex with Vitamin C
Swanson
4.7
★★★★★
(2248 ratings)
Provides a broader range of B vitamins plus a significant dose of Vitamin C, offering more comprehensive support for overall stress and general health.
78 Performance 
Folic Acid B6 & B12
Mason Natural
4.8
★★★★★
(2530 ratings)
Combines B6 with Folic Acid and B12, crucial B vitamins that work together, offering a targeted synergistic approach beyond isolated B6.
98 Budget
P-5-P/Mag
Terry Naturally
4.8
★★★★★
(2668 ratings)
Offers the active P-5-P B6 along with beneficial magnesium and zinc at a significantly lower price per serving.
93 Budget
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
A more affordable option for a pure P-5-P supplement, offering good value for money.
95 Budget
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
Contains P-5-P at a much lower price per serving, providing a budget-friendly option for the active form of B6.
93 Value
P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength
Swanson
4.8
★★★★★
(1062 ratings)
Offers a pure P-5-P supplement at a significantly lower price point, providing excellent value for the active form of B6.
95 Value
Vitamin B-6 50 mg
Nature's Way
4.8
★★★★★
(1720 ratings)
Contains the active P-5-P form of B6 at a substantially lower price per serving, representing outstanding value for high-quality B6.
98 Value
P-5-P/Mag
Terry Naturally
4.8
★★★★★
(2668 ratings)
Combines the active P-5-P B6 with beneficial minerals at a lower price per serving, offering an excellent synergistic blend at a competitive cost.
87 Performance
B-Complex '100'
Solgar
4.7
★★★★★
(446 ratings)
For comprehensive B vitamin support, this product offers a full spectrum of B vitamins that work synergistically for energy, brain, and general health, which may be preferred over isolated P-5-P.
86 Performance
Super Stress B-Complex with Vitamin C
Swanson
4.7
★★★★★
(2248 ratings)
Provides a broader range of B vitamins plus a significant dose of Vitamin C, offering more comprehensive support for overall stress and general health.
78 Performance
Folic Acid B6 & B12
Mason Natural
4.8
★★★★★
(2530 ratings)
Combines B6 with Folic Acid and B12, crucial B vitamins that work together, offering a targeted synergistic approach beyond isolated B6.