P-5-P 50 mg
Nutricost
P-5-P 50 mg
4.8
★ ★ ★ ★ ★
(598 ratings)
Vitamin B6 50 mg
Score 95.0
An outstanding value P-5-P supplement, offering a good 50mg dose of the active form at an exceptionally low price per serving.
Quantity: 240 Capsule(s)Servings size: 1 Capsule(s) (240 servings)
Selected goals:
Other goals:
Energy
Brain Health
Mood Support
General Health
leaderboard Score 95.0
An outstanding value P-5-P supplement, offering a good 50mg dose of the active form at an exceptionally low price per serving.
insights Analysis
Nutricost's P-5-P 50 mg is a standout product, providing the active Pyridoxal 5-Phosphate form of B6, which is superior for absorption and utilization compared to standard pyridoxine HCl. The 50mg dosage is well-suited for many therapeutic needs, from supporting methylation to neurotransmitter synthesis. What truly differentiates this product is its remarkable value: with 240 servings, the price per serving is incredibly low at just 7 units. While Nutricost is often seen as a budget brand, online reviews generally attest to its efficacy and consistency for basic supplements, and nutritionists would appreciate the bioavailable form at such an accessible price.
- Contains Pyridoxal 5-Phosphate (P-5-P), the active and most bioavailable form of Vitamin B6.
- Provides a good 50mg dosage of P-5-P, suitable for a wide range of needs.
- Exceptional value with a very low price per serving due to 240 capsules, making it highly affordable for long-term use.
- Nutricost is considered a value brand, which might lead some consumers to question overall quality control compared to premium brands, though reviews are generally positive.
- The large quantity might be excessive for individuals who only need occasional or short-term supplementation.
$16.95($0.07 per serving)
 iHerb | $ 16.95 |
bolt Effectiveness for goals
Yes, Vitamin B6 is a widely recognized and often recommended treatment for nausea and vomiting in pregnancy, commonly known as morning sickness. It is considered a first-line pharmacological therapy for mild to moderate symptoms. Pregnant individuals should consult their healthcare provider before taking any supplements.
Vitamin B6, or pyridoxine, is crucial for over 100 enzyme reactions, primarily involved in protein metabolism, red blood cell formation, and nervous system health. It plays a key role in metabolic processes that convert food into energy. Maintaining adequate B6 levels supports overall health and proper bodily functions.
Absolutely, Vitamin B6 is vital for brain development and function, and for maintaining a healthy nervous system. It is involved in the synthesis of several key neurotransmitters, such as serotonin, dopamine, and GABA, which regulate mood, sleep, and cognitive processes. Adequate B6 intake is essential for proper nerve signaling.
Some studies suggest that Vitamin B6 supplementation may help reduce certain PMS symptoms, particularly mood swings, irritability, and breast tenderness. The exact mechanism is not fully understood, but it may involve its role in neurotransmitter synthesis. However, evidence is mixed, and more robust research is needed.
Vitamin B6 is involved in the production of neurotransmitters like serotonin and norepinephrine, which are critical for mood regulation. Some research indicates that B6 supplementation may positively influence mood and reduce symptoms of depression, particularly in individuals with a deficiency. However, it should not replace prescribed treatments for mental health conditions.
schedule Dosage, timing & forms
The Recommended Dietary Allowance (RDA) for adult men and women (19-50 years) is 1.3 mg per day. For those over 50, it is 1.7 mg for men and 1.5 mg for women. These recommendations are for healthy individuals.
Yes, taking excessively high doses of Vitamin B6, particularly from supplements, can be harmful. The most well-known adverse effect is sensory neuropathy, which can cause numbness and tingling in the extremities. This risk increases with doses significantly above the Tolerable Upper Intake Level (UL) of 100 mg/day.
The Tolerable Upper Intake Level (UL) for Vitamin B6 in adults is 100 mg per day. Consuming amounts significantly above this UL, particularly from supplements, can lead to adverse effects like peripheral neuropathy. It is advisable not to exceed this limit without professional guidance.
There is no specific "best" time to take Vitamin B6; it can be taken at any time of day. Consistency in taking the supplement is generally more important than the exact timing. Some individuals may prefer to take it with a meal to avoid potential stomach upset.
Vitamin B6 supplements commonly contain pyridoxine hydrochloride (pyridoxine HCl). The active coenzyme form, pyridoxal 5'-phosphate (P5P), is also available in some supplements. Other forms like pyridoxal and pyridoxamine also exist in food.
health_and_safety Safety & interactions
Long-term intake of high doses, typically exceeding 200 mg per day, can lead to sensory peripheral neuropathy, characterized by numbness, tingling, and pain in the extremities. Other less common side effects might include skin lesions, photosensitivity, and gastrointestinal issues. These effects usually resolve after discontinuing supplementation.
For adults, the tolerable upper intake level (UL) for Vitamin B6 is set at 100 mg per day from supplements and fortified foods. Consuming amounts above this UL regularly increases the risk of adverse effects, primarily neurological damage. This limit is established to prevent potential harm.
The primary and most concerning symptom of Vitamin B6 toxicity, typically from chronic high doses, is sensory peripheral neuropathy. This involves symptoms like numbness, tingling, and burning pain, often starting in the hands and feet. Other less common signs might include skin lesions or gastrointestinal upset.
Yes, Vitamin B6 can interact with several medications. For instance, it may reduce the effectiveness of levodopa (used for Parkinson's disease) and can interact with anti-seizure medications like phenytoin and phenobarbital. It is important to consult a healthcare provider when combining Vitamin B6 supplements with prescription drugs.
Vitamin B6 is generally considered safe during pregnancy and breastfeeding when taken within recommended dietary allowances. Higher doses might be used under medical supervision for specific conditions like severe morning sickness. Always discuss any supplementation with a healthcare provider to ensure appropriate dosing.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Vitamin B6 (Pyridoxal 5-Phosphate) | 50 mg |
Categories
Vitamin B6 95.0
This product is a top performer in the Vitamin B6 category, offering the highly desirable P-5-P form at an effective 50mg dose with an unmatched price per serving, setting a high standard for value and bioavailability.
Goals
Energy 95.0
The 50mg P-5-P dose is highly effective for supporting energy metabolism, and the excellent value ensures consistent long-term use, providing robust and sustained energy support.
Brain Health 95.0
P-5-P is crucial for neurotransmitter synthesis; the 50mg dose from this cost-effective product provides strong and accessible support for optimal brain function, making it easy to maintain consistent intake.
Mood Support 95.0
With its active P-5-P form and adequate 50mg dosage, this product effectively contributes to the production of mood-regulating neurotransmitters, offering excellent and affordable support for emotional well-being.
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