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MSM 1000 mg

Source Naturals
4.6
★ ★ ★ ★ ★
(446 ratings)
Molybdenum 160 mcg
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Score78
Transparent MSM, vitamin C, and molybdenum amounts provide focused sulfur and antioxidant support. The formula is more compelling for connective tissue and sulfite metabolism than broad detoxification.
How scoring works
Quantity:120 Tablet(s) • (60 servings)
Goals:
Detoxification

Score 78

Transparent MSM, vitamin C, and molybdenum amounts provide focused sulfur and antioxidant support. The formula is more compelling for connective tissue and sulfite metabolism than broad detoxification.
How scoring works
$12.06($0.20 per serving)
iHerb
$ 12.06
Amazon
$ 16.91
Vitacost
$ 12.06
Vitacost
$ 12.06
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Analysis

MSM supplies two grams per serving and dominates the formula with a meaningful sulfur compound amount. Vitamin C contributes antioxidant and collagen-related support, while molybdenum serves as a cofactor for sulfite oxidase.

The molybdenum amount is useful, but the generic chelate description does not identify its ligand or a verified source. MSM has a clearer role in joint and connective-tissue support than in broad toxin clearance.

All active amounts are disclosed, which makes the product easier to assess than a proprietary detox blend. Two tablets per serving are reasonable, though users should choose it for its specific ingredients rather than a sweeping cleanse claim.

Who is it for
  • Adults seeking MSM with antioxidant support
  • People wanting molybdenum alongside a substantial sulfur compound
Best for
  • Connective-tissue support
  • Supporting sulfite metabolism and antioxidant intake

Pros

  • Provides two grams of MSM
  • Clearly discloses all active amounts
  • Includes vitamin C and molybdenum

Cons

  • Molybdenum chelate ligand is not identified
  • MSM is not a comprehensive detox ingredient
  • Does not support gut binding or bile flow

Warnings

  • Two grams of MSM may cause digestive upset, headache, or loose stools in sensitive users.
  • Vitamin C may add stomach irritation or diarrhea when combined with other high-dose vitamin C products.
  • Avoid stacking multiple molybdenum supplements because unnecessary long-term excess may disturb copper balance.

Nutrient quality

83 Highest impact

A substantial MSM amount is paired with useful vitamin C and molybdenum amounts. The generic molybdenum chelate does not identify its ligand.

Ingredient transparency

79 High impact

Principal active ingredients have specific amounts and no proprietary blend hides their doses. Complete use directions and a full other-ingredients list are not included in the supplied facts.

Customer satisfaction

66 High impact

The supplied average rating is strong, and review volume provides a useful but not extensive signal. No detailed comments are provided to assess repeated complaints or whether experiences match the intended use.

Value for money

82 Highest impact

Meaningful dosing and a low recurring cost support strong practical value. The main value trade-off comes from incomplete use and other-ingredient details.

Report analysis

Goals

Detoxification
Detoxification
Impact
High effect
C Goal FitB Strength of SupportC+ CoverageB Formula Quality
Molybdenum · 160 mcgVitamin C · 250 mg

Molybdenum directly supports sulfite oxidase, while vitamin C contributes antioxidant protection. The mineral amount is well suited to targeted enzyme support and is fully disclosed.

The generic chelate does not identify its ligand or a verified branded source. MSM dominates the formula and may supply sulfur, but its direct contribution to the selected goal is less clear than the molybdenum contribution.

Study evidence
Molybdenum Adverse 1 study
Vitamin C Supportive 9 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 250 mg
Molybdenum (Molybdenum Chelate)
 160 mcg
Methylsulfonylmethane
2 Gram(s)
Gluten Free Adults 18–50 Dairy Free Sugar Free Women Vegetarian
Report overview
Molybdenum (Molybdenum Chelate) · 160 mcg OverallScore70
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The molybdenum amount sits in the preferred range and remains comfortably below the adult upper limit. A generic chelate description leaves its exact ligand and absorption quality uncertain. Low serving cost provides good value, though the source lacks the detail needed for a top-tier assessment.

View ingredientView products
Loading alternative details
93 Performance

NAC Detox Regulators

Doctor's Best
Its fully quantified formula pairs 600 mg N-acetylcysteine with 50 mcg selenium and 50 mcg molybdenum glycinate chelate. The combination has strong nutrient-quality and detoxification alignment evidence, giving it broader goal coverage than the original MSM-based formula, without making cost the deciding factor.
88 Performance

NAC+

KAL
Its formula combines 600 mg N-acetyl-L-cysteine with 450 mcg total molybdenum from aspartate, citrate, and orotate forms. The three disclosed molybdenum forms and NAC provide broader ingredient coverage than the original MSM-based formula, without making cost the deciding factor.
90 Performance

Moly-B

Carlson
Its focused formula supplies 500 mcg molybdenum as a glycinate chelate in a single-mineral tablet. Its high molybdenum amount and strong collection fit provide more focused mineral support than the original MSM-based formula, without making cost the deciding factor.
95 Budget

NAC 600 mg

NOW
Its fully quantified formula combines 600 mg NAC with 25 mcg selenium and 50 mcg sodium molybdate. Its lower recurring cost and stronger value evidence make it a more economical choice than the original MSM-based formula.
92 Budget

Chelated Molybdenum

Solgar
Its focused formula supplies 150 mcg molybdenum as an amino acid chelate without unrelated active ingredients. Its lower recurring cost and stronger value evidence make it a more economical choice than the original MSM-based formula.
93 Budget

Moly-B

Carlson
Its focused formula supplies 500 mcg molybdenum as a glycinate chelate across 300 servings. Its lower recurring cost and stronger value evidence make it a more economical choice than the original MSM-based formula.
95 Value

NAC 600 mg

NOW
Its fully quantified formula combines 600 mg NAC with 25 mcg selenium and 50 mcg sodium molybdate. Its strong nutrient-quality and value evidence balances detoxification coverage with cost-effectiveness better than the original MSM-based formula.
92 Value

NAC Detox Regulators

Doctor's Best
Its fully quantified formula pairs 600 mg N-acetylcysteine with 50 mcg selenium and 50 mcg molybdenum glycinate chelate. Its strong nutrient-quality and goal-alignment evidence offers a practical balance of coverage and value compared with the original MSM-based formula.
82 Value

Reduced Glutathione Complex 50 mg Orange Flavored

Source Naturals
Its formula combines 50 mg glutathione with 120 mcg chelated molybdenum and 1.6 mg riboflavin. Glutathione adds a distinct detoxification-related pathway while the moderate recurring cost improves the quality-to-cost balance versus the original MSM-based formula.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Human molybdenum exposure risk in industrial regions of China: New critical effect indicators and reference dose.
    Kuang HX; Li MY; Zeng XW; Chen D; Zhou Y; Zheng T; Xiang MD; Wu QZ; Chen XC; Dong GH; Yu YJ · Ecotoxicology and environmental safety · 2024
    Cross-sectional study2,267 participantsDetoxification forMolybdenum
  2. Vitamin C supplementation ameliorates liver function profile and antiviral treatment response in Hepatitis C patients.
    Nayila I; Javed MS; Khan MA; Hussain G; Raza Naqvi SA; Ali S; Jabeen Z; Shahnawaz S; Akram R; Iman T; Hassan Dogar MZ; Malik SA · Pakistan journal of pharmaceutical sciences · 2022
    Non-randomized trial200 participantsDetoxification forVitamin C
  3. Effect of ascorbic acid-rich diet on in vivo-induced oxidative stress.
    Alleva R; Di Donato F; Strafella E; Staffolani S; Nocchi L; Borghi B; Pignotti E; Santarelli L; Tomasetti M · The British journal of nutrition · 2012
    Non-randomized trial46 participantsDetoxification forVitamin C
  4. Dietary Vitamin C Intake Is Associated With Improved Liver Function and Glucose Metabolism in Chinese Adults.
    Luo X; Zhang W; He Z; Yang H; Gao J; Wu P; Ma ZF · Frontiers in nutrition · 2022
    Observational study8,307 participantsDetoxification forVitamin C
  5. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA; Yoder AR; Bajad S; Beckwith MD; Bellehumeur JL; Graziano FM · Journal of acquired immune deficiency syndromes (1999) · 2005
    Observational studyDetoxification forVitamin C
  6. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN; Kurian JR; Bajad SU; Maki JE; Yoder AR; Guzinski MV; Graziano FM; Trepanier LA · Toxicology · 2006
    Clinical trial53 participantsDetoxification forVitamin C