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Vitamin B6 500 mg

Vitamatic
4.8
★ ★ ★ ★ ★
(84 ratings)
Vitamin B6 500 mg
Product Image
Score58
An extreme pyridoxine dose with a poor safety profile for routine use, regardless of its low price.
How scoring works
Quantity:120 Tablet(s) • (120 servings)
Goals:

Score 58

An extreme pyridoxine dose with a poor safety profile for routine use, regardless of its low price.
How scoring works
$14.99($0.12 per serving)
Vitacost
$ 14.99
iHerb
$ 15.99
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Analysis

Each tablet provides 500 mg of pyridoxine hydrochloride with no supporting nutrients. The amount is five times a commonly referenced chronic-use ceiling and is not reasonable for routine self-directed supplementation.

Pyridoxine requires conversion to P-5-P, while very high repeated exposure may damage peripheral nerves. The fixed tablet offers no practical way to reduce the serving accurately.

Low cost is irrelevant when the full dose is poorly matched to safe everyday use. A much lower-dose active-form product is more appropriate for nearly all routine users.

Who is it for
  • Only adults under explicit clinician-directed use
  • Users verifying a specialized short-term protocol
  • People who will not combine it with any other B6
Best for
  • Strictly supervised high-dose use
  • Single-ingredient tracking
  • Very limited specialized protocols

Pros

  • Clear single active
  • Low cost
  • Simple label

Cons

  • Extremely excessive amount
  • Uses precursor-form pyridoxine
  • Fixed tablet prevents sensible dose adjustment

Warnings

  • Repeated 500 mg B6 exposure may cause severe or persistent peripheral nerve injury
  • Do not use without explicit clinical supervision
  • Stop immediately and seek medical care for numbness, burning, tingling, weakness, or balance problems

Nutrient quality

43 Lower impact

The single-active formula is focused but uses precursor-form vitamin B6. Its extreme amount creates a serious chronic-use safety concern.

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Ingredient transparency

79 High impact

All listed active amounts are clear and no proprietary blend hides a dose. Inactive ingredients and complete daily-use directions are not supplied.

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Customer satisfaction

66 High impact

The supplied aggregate rating is particularly strong. The small review count provides limited rating confidence.

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Value for money

39 Lower impact

A simple tablet and low serving cost offer superficial affordability. The extreme dose makes practical value very poor.

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Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride)
 500 mg
Adults 18–50 Sugar Free
Report overview
Vitamin B6 (Pyridoxine Hydrochloride) · 500 mg OverallScore55
D+ Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The 500 mg dose greatly exceeds the stated safety ceiling and creates a serious neuropathy risk with repeated use. Pyridoxine hydrochloride is also a precursor form with no listed riboflavin cofactor. Very low cost cannot compensate for the excessive dose.

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89 Performance

P-5-P 50 mg

Country Life
<p>Active pyridoxal phosphate provides a meaningful B6 serving in a focused format. Compared with the original, the active B6 form avoids a conversion step, although the supplied dose may still exceed ordinary nutritional needs.</p>
89 Performance

BioCoenzymated Pyridoxal 5'-Phosphate 50 mg

Natural Factors
<p>Active pyridoxal phosphate provides a meaningful B6 serving in a focused format. Compared with the original, the active B6 form avoids a conversion step, although the supplied dose may still exceed ordinary nutritional needs.</p>
89 Performance

P-5-P (Pyridoxal-5-Phosphate) 40 mg Double Strength

Swanson
<p>Active pyridoxal phosphate provides a meaningful B6 serving in a focused format. Compared with the original, the active B6 form avoids a conversion step, although the supplied dose may still exceed ordinary nutritional needs.</p>
80 Budget

B6 100 mg

Spring Valley
<p>Pyridoxine hydrochloride provides a clearly stated but very high B6 serving. Its lower serving cost improves affordability versus the original, although the supplied safety and form limitations still matter for long-term use.</p>
80 Budget

B-6 100 mg

21st Century
<p>Pyridoxine hydrochloride provides a clearly stated but very high B6 serving. Its lower serving cost improves affordability versus the original, although the supplied safety and form limitations still matter for long-term use.</p>
80 Budget

B-6 100 mg

NOW
<p>Pyridoxine hydrochloride provides a clearly stated but very high B6 serving. Its lower serving cost improves affordability versus the original, although the supplied safety and form limitations still matter for long-term use.</p>
87 Value

Vitamin B-6 50 mg

Nature's Way
<p>A mixed active and precursor B6 blend provides a meaningful B6 serving in a focused format. It combines retaining an active or partly active B6 form with a lower serving cost, although the dose and long-term-use cautions remain important.</p>
84 Value

P-5-P 50 mg

Nutricost
<p>Active P-5-P provides ready-to-use vitamin B6 in a simple high-potency capsule. It combines retaining an active or partly active B6 form with a lower serving cost, although the dose and long-term-use cautions remain important.</p>
85 Value

Vitamin B6 25 mg

Solgar
<p>Pyridoxine hydrochloride provides a meaningful B6 serving in a focused format. It combines keeping the ingredient panel focused and clearly stated with a lower serving cost, although the dose and long-term-use cautions remain important.</p>
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