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Multi Collagen Beauty Night

Codeage
4.8
★ ★ ★ ★ ★
(279 ratings)
Magnesium 225 mg
Melatonin 6 mg
Protein (unspecified) 3.1 Gram(s)
Product Image
Score66
A sleep-focused formula led by high-quality magnesium glycinate and a strong melatonin amount. Hidden blends, five capsules, and possible next-day grogginess are the main trade-offs.
How scoring works
Quantity:150 Capsule(s) • (30 servings)
Goals:
Sleep Support
General Health
Energy
Bone Health
Digestive Health
Testosterone Support
Cardiovascular Support

Score 66

A sleep-focused formula led by high-quality magnesium glycinate and a strong melatonin amount. Hidden blends, five capsules, and possible next-day grogginess are the main trade-offs.
How scoring works
$39.99($1.33 per serving)
iHerb
$ 39.99
Pure Formulas
$ 39.99
BodyBuilding.com
$ 39.99
Vitacost
$ 39.99
iHerb
$ 39.99
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Analysis

Magnesium glycinate is the strongest part of the formula, with a meaningful elemental amount and a well-regarded chelated form. It may support normal muscle relaxation and nervous-system function without relying on a broad mineral blend.

Melatonin directly targets sleep timing, but the listed amount is high enough to increase next-morning grogginess or vivid dreams in sensitive users. The combination fits occasional or deliberately timed nighttime use better than a general daily multivitamin.

The collagen complex makes a modest structural contribution, while the beauty-night complex does not disclose its individual ingredients or doses. A five-capsule serving and limited blend transparency make the product less appealing for users focused mainly on magnesium or collagen.

Who is it for
  • Adults seeking magnesium with bedtime melatonin
  • Users who already tolerate a higher melatonin amount
  • People comfortable with a multi-capsule night routine
Best for
  • Targeted nighttime use
  • Magnesium glycinate supplementation
  • Sleep-timing support

Pros

  • Uses TRAACS magnesium glycinate
  • Meaningful magnesium amount
  • Zero listed sugar

Cons

  • Melatonin amount may be excessive for sensitive users
  • Beauty blend is not itemized
  • Five capsules per serving

Warnings

  • Melatonin can cause next-morning grogginess, vivid dreams, or headache at the listed amount.
  • Do not take the serving before driving or combine it with alcohol, sleep medicines, or other sedatives.
  • Magnesium can reduce absorption of thyroid medicine and certain antibiotics when taken too close together.

Nutrient quality

78 High impact

Magnesium glycinate provides a useful form and amount, while melatonin directly fits nighttime use. The elevated melatonin amount and undisclosed blend components reduce balance and dosing confidence.

Ingredient transparency

54 Moderate impact

Magnesium, collagen complex, beauty complex, and melatonin each have a total amount. The beauty complex hides its components, and the supplied facts omit clear directions and other ingredients.

Customer satisfaction

70 High impact

The aggregate rating is strong and comes from a useful volume of responses. No review text is supplied, so recurring complaints and purpose-specific experiences cannot be verified.

Value for money

66 High impact

The serving delivers a quality magnesium chelate alongside collagen and melatonin. A relatively high serving cost and limited blend disclosure weaken the value case.

Report analysis

Goals

Sleep Support
Sleep Support
Impact
High effect
A Goal FitB- Strength of SupportB+ CoverageC Formula Quality
Magnesium · 225 mgMelatonin · 6 mg

Melatonin directly supports sleep timing, while magnesium glycinate adds a separate relaxation and muscle-support pathway. The combination is clearly sleep-oriented, although collagen mainly serves the beauty positioning rather than sleep quality.

The magnesium amount is meaningful, but 6 mg of melatonin is higher than the lower physiological range often sufficient for sleep onset. That amount may increase vivid dreams or morning grogginess, especially in sensitive users.

Study evidence
Magnesium Supportive 23 studies
Melatonin Supportive 181 studies
General Health
Stress Resilience
General Health
Impact
High effect
B Goal FitA- Strength of SupportC+ CoverageB- Formula Quality
Magnesium · 225 mg

Chelated magnesium gives the formula meaningful foundational value, while melatonin adds situational circadian support. Collagen broadens the product toward structural and beauty needs rather than comprehensive daily nutrition.

The TRAACS magnesium dose is clear and well aligned with supplementation, but the collagen and beauty blend details are limited. The melatonin amount may cause next-morning grogginess in sensitive users and is better suited to targeted nighttime use.

Study evidence
Magnesium Supportive 114 studies
Melatonin Supportive 69 studies
Energy
Energy
Impact
High effect
B- Goal FitA- Strength of SupportC- CoverageC Formula Quality
Magnesium · 225 mg

Chelated magnesium supports ATP-dependent enzymes, while the night formula is aimed at sleep and recovery rather than daytime energy. Better rest may indirectly help vitality, but it is not an acute or broad energy strategy.

The 225 mg TRAACS magnesium glycinate amount meets the stated target and uses a well-absorbed form. The 6 mg melatonin dose can cause marked drowsiness and next-day grogginess, so the product is suitable only near bedtime and not before driving or operating machinery.

Study evidence
Magnesium Supportive 4 studies
Bone Health
Bone Mineral Density
Bone Health
Impact
High effect
B- Goal FitB+ Strength of SupportB- CoverageC- Formula Quality
Magnesium · 225 mg

Magnesium and collagen provide two relevant bone-support pathways: mineral metabolism and the protein matrix. The product is still designed mainly for sleep and beauty rather than comprehensive skeletal support.

TRAACS magnesium glycinate is well dosed and clearly disclosed. Collagen is present in a meaningful blend amount, while the undisclosed blend composition and sleep actives reduce bone-specific transparency and focus.

Study evidence
Magnesium Supportive 48 studies
Digestive Health
Bowel Regularity
Digestive Health
Impact
High effect
C+ Goal FitA Strength of SupportC- CoverageD+ Formula Quality
Magnesium · 225 mg

TRAACS magnesium glycinate may support intestinal muscle function, while collagen adds a secondary structural angle. The formula is designed mainly for beauty and sleep rather than regularity or meal-time digestion.

A clearly disclosed magnesium amount and validated chelate support useful depth. Melatonin and the broader blend dilute the digestive focus without adding another clear gut pathway.

Study evidence
Magnesium Supportive 50 studies
Testosterone Support
Free Testosterone Support
Testosterone Support
Impact
High effect
C- Goal FitA Strength of SupportD+ CoverageD+ Formula Quality
Magnesium · 225 mgMelatonin · 6 mg

Patented magnesium glycinate gives the blend a credible nutritional link to healthy hormone function. Melatonin and collagen support sleep and beauty goals more directly than testosterone pathways.

The magnesium amount and TRAACS form are strong, but the formula lacks zinc, vitamin D, boron, or a clearly dosed adaptogen. The 6 mg melatonin amount may cause morning grogginess in sensitive users.

Study evidence
Magnesium Disputed 5 studies
Melatonin No effect 6 studies

Ingredients

IngredientAmount per serving
Calories
13 Calorie(s)
Sugar
0 Gram(s)
Cholesterol
0 Gram(s)
Protein
3.1 Gram(s)
Magnesium (TRAACS Magnesium Glycinate)
 225 mg
Multi-Collagen Complex
2000 mg
Beauty Night Complex
255 mg
Melatonin
6 mg
Adults 18–50 Women
Report overview
Magnesium (TRAACS Magnesium Glycinate) · 225 mg OverallScore88
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB- Value
+1

Patented TRAACS magnesium glycinate provides a highly absorbable form with clear elemental dosing. The amount is therapeutically aligned, although the mixed collagen formula lacks a preferred magnesium cofactor. A high serving cost is partly justified by the validated chelate.

View ingredientView products
Melatonin · 6 mg OverallScore49
F Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value

The capsule blend combines melatonin with magnesium and collagen, but it is not designed for rapid or sustained melatonin release. Its melatonin dose is above the range most closely aligned with natural sleep rhythms and may cause morning grogginess in sensitive users. Three capsules are needed per serving, and the high cost is only partly offset by the broader multi-ingredient formula.

View ingredientView products
Loading alternative details
83 Performance

Magnesium Citrate

Nature Made
Compared with 6 mg of Melatonin, 255 mg of Beauty Night Complex and 2000 mg of Multi-Collagen Complex, the alternative provides 1 Gram(s) of Protein and 250 mg of Magnesium as Magnesium Citrate, and the supplied analysis indicates stronger alignment with Magnesium. Complete softgel ingredients and detailed intake guidance are missing, but the core active is clear and sensibly dosed.
83 Performance

Sleep Nighttime Powder

youtheory
Compared with 6 mg of Melatonin, 255 mg of Beauty Night Complex and 2000 mg of Multi-Collagen Complex, the alternative provides 200 mg of Magnesium as Magnesium Citrate, 3000 mg of L-Glycine and 250 mg of L-Tryptophan, and the supplied analysis indicates stronger alignment with Magnesium, Melatonin. Combining 5-HTP and tryptophan may intensify serotonin effects with SSRIs, SNRIs, or MAO inhibitors despite the otherwise thoughtful dosing.
74 Performance

NightRest With Melatonin

Source Naturals
Compared with 6 mg of Melatonin, 255 mg of Beauty Night Complex and 2000 mg of Multi-Collagen Complex, the alternative provides 300 mg of Magnesium as Magnesium Chelate, 5 mg of Sodium and 500 mg of GABA, and the supplied analysis indicates stronger alignment with Magnesium, Melatonin. A high melatonin amount may cause next-day drowsiness, while several supporting doses and source details are too limited for confident daily use.
83 Budget

Sleep Nighttime Powder

youtheory
The supplied serving cost is lower, while the formula provides 200 mg of Magnesium as Magnesium Citrate, 3000 mg of L-Glycine and 250 mg of L-Tryptophan. Combining 5-HTP and tryptophan may intensify serotonin effects with SSRIs, SNRIs, or MAO inhibitors despite the otherwise thoughtful dosing.
83 Budget

Magnesium Citrate

Nature Made
The supplied serving cost is lower, while the formula provides 1 Gram(s) of Protein and 250 mg of Magnesium as Magnesium Citrate. Complete softgel ingredients and detailed intake guidance are missing, but the core active is clear and sensibly dosed.
74 Budget

NightRest With Melatonin

Source Naturals
The supplied serving cost is lower, while the formula provides 300 mg of Magnesium as Magnesium Chelate, 5 mg of Sodium and 500 mg of GABA. A high melatonin amount may cause next-day drowsiness, while several supporting doses and source details are too limited for confident daily use.
83 Value

Magnesium Citrate

Nature Made
1 Gram(s) of Protein and 250 mg of Magnesium as Magnesium Citrate offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Complete softgel ingredients and detailed intake guidance are missing, but the core active is clear and sensibly dosed.
83 Value

Sleep Nighttime Powder

youtheory
200 mg of Magnesium as Magnesium Citrate, 3000 mg of L-Glycine and 250 mg of L-Tryptophan offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. Combining 5-HTP and tryptophan may intensify serotonin effects with SSRIs, SNRIs, or MAO inhibitors despite the otherwise thoughtful dosing.
74 Value

NightRest With Melatonin

Source Naturals
300 mg of Magnesium as Magnesium Chelate, 5 mg of Sodium and 500 mg of GABA offers a practical value trade-off because the supplied serving cost is lower and the value analysis is stronger. A high melatonin amount may cause next-day drowsiness, while several supporting doses and source details are too limited for confident daily use.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  2. Effects of zinc and magnesium supplements on postpartum depression and anxiety: A randomized controlled clinical trial.
    Fard FE; Mirghafourvand M; Mohammad-Alizadeh Charandabi S; Farshbaf-Khalili A; Javadzadeh Y; Asgharian H · Women & health · 2017
    Randomized trial99 participantsStress Relief forMagnesium
  3. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep.
    Nielsen FH; Johnson LK; Zeng H · Magnesium research · 2011
    Randomized trial100 participantsSleep Support forMagnesium
  4. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  5. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
    Rawji A; Peltier MR; Mourtzanakis K; Awan S; Rana J; Pothen NJ; Afzal S · Cureus · 2024
    Systematic review15 studies pooledStress Relief forMagnesium
  6. The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature.
    Arab A; Rafie N; Amani R; Shirani F · Biological trace element research · 2023
    Systematic review7,582 participants9 studies pooledSleep Support forMagnesium
  7. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  8. Role of magnesium supplementation in the treatment of depression: A randomized clinical trial.
    Tarleton EK; Littenberg B; MacLean CD; Kennedy AG; Daley C · PloS one · 2017
    Randomized trial126 participantsStress Relief forMagnesium
  9. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
    Khalid S; Bashir S; Mehboob R; Anwar T; Ali M; Hashim M; Waseem H; Basharat S · Frontiers in endocrinology · 2024
    Randomized trial320 participantsSleep Support forMagnesium
  10. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  11. Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study.
    Zhang Y; Chen C; Lu L; Knutson KL; Carnethon MR; Fly AD; Luo J; Haas DM; Shikany JM; Kahe K · Sleep · 2022
    Cohort study3,964 participantsSleep Support forMagnesium
  12. Effects of Intravenous Esketamine or Magnesium Sulfate on Early Postoperative Negative Emotions and Pain in Patients Undergoing Endoscopic Sinus Surgery: A Randomized Controlled Trial.
    Wang L; Zhou J; Liu Q; Qian K; Wang L; Xie C · Therapeutics and clinical risk management · 2026
    Randomized trial137 participantsStress Relief forMagnesium
  13. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  14. Lidocaine vs. magnesium: effect on analgesia after a laparoscopic cholecystectomy.
    Saadawy IM; Kaki AM; Abd El Latif AA; Abd-Elmaksoud AM; Tolba OM · Acta anaesthesiologica Scandinavica · 2010
    Randomized trial120 participantsSleep Support forMagnesium
  15. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.
    Noah L; Dye L; Bois De Fer B; Mazur A; Pickering G; Pouteau E · Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Randomized trialStress Relief forMagnesium
  16. Melatonin Treatment for Sleep Disorders in Parkinson's Disease: A Meta-Analysis and Systematic Review.
    Ma H; Yan J; Sun W; Jiang M; Zhang Y · Frontiers in aging neuroscience · 2022
    Meta-analysis7 studies pooledSleep Support forMelatonin
  17. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
    Abbasi B; Kimiagar M; Sadeghniiat K; Shirazi MM; Hedayati M; Rashidkhani B · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013
    Randomized trial46 participantsSleep Support forMagnesium
  18. Effect of short-term magnesium supplementation on anxiety, depression and sleep quality in patients after open-heart surgery.
    Saba S; Faizi F; Sepandi M; Nehrir B · Magnesium research · 2022
    Non-randomized trial60 participantsStress Relief forMagnesium
  19. Effects of Melatonin Treatment on Perioperative Sleep Quality: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials.
    Gao Y; Chen X; Zhou Q; Song J; Zhang X; Sun Y; Yu M; Li Y · Nature and science of sleep · 2022
    Meta-analysis725 participants10 studies pooledSleep Support forMelatonin
  20. Magnesium supplements, sleep quality, and nocturnal leg cramps: a combination of cross-sectional and prospective studies.
    Stadie N; Heinzer R; Marques-Vidal P · European journal of nutrition · 2026
    Cohort study3,887 participantsSleep Support forMagnesium
  21. Effects of Combined Intravenous and Topical Magnesium Sulfate Administration on Pain, Stress, and Functional Recovery After Total Knee Arthroplasty: A Prospective, Randomized, Blinded Controlled Trial.
    Wang Q; Wang Y; Hu J; Chen C; Yang J; Kang P · Drug design, development and therapy · 2026
    Randomized trial150 participantsStress Relief forMagnesium
  22. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  23. A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
    Barna O; Lohoida P; Holovchenko Y; Bazylevych A; Velychko V; Hovbakh I; Bula L; Shechter M · Nutrition journal · 2021
    Randomized trial175 participantsSleep Support forMagnesium
  24. Effects of dry needling compared to magnesium infiltration in trigger points for patients with myofascial pain syndrome: a randomized controlled study in Tunisia.
    Dhouibi J; Moncer R; Kalbousi N; Gaddour M; Laayouni S; Ouanes W; Kacem B; Jemni S · Korean journal of family medicine · 2026
    Randomized trial45 participantsStress Relief forMagnesium
  25. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  26. The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial.
    Lopresti AL; Smith SJ · Frontiers in nutrition · 2026
    Randomized trial100 participantsSleep Support forMagnesium
  27. The association between dietary intake of magnesium and psychiatric disorders among Iranian adults: a cross-sectional study.
    Anjom-Shoae J; Sadeghi O; Hassanzadeh Keshteli A; Afshar H; Esmaillzadeh A; Adibi P · The British journal of nutrition · 2019
    Cross-sectional study3,172 participantsStress Relief forMagnesium
  28. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  29. Diabetes modifies the association between magnesium and insomnia, but not depressive symptomatology, in Puerto Rican adults: a prospective cohort study.
    Chen F; Mangano KM; Scott TM; Li W; Falcón LM; Gao X; Garelnabi M; Tucker KL · The American journal of clinical nutrition · 2026
    Cohort study613 participantsSleep Support forMagnesium
  30. Blood Magnesium Level and Selected Oxidative Stress Indices in Lead-Exposed Workers.
    Wyparło-Wszelaki M; Wąsik M; Machoń-Grecka A; Kasperczyk A; Bellanti F; Kasperczyk S; Dobrakowski M · Biological trace element research · 2021
    Cross-sectional study232 participantsStress Relief forMagnesium
  31. Association between Serum Magnesium and Fractures: A Systematic Review and Meta-Analysis of Observational Studies.
    Dominguez LJ; Veronese N; Ciriminna S; Pérez-Albela JL; Vásquez-López VF; Rodas-Regalado S; Di Bella G; Parisi A; Tagliaferri F; Barbagallo M · Nutrients · 2023
    Meta-analysis119,755 participants4 studies pooledBone Health forMagnesium
  32. Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review.
    Hung CH; Kwok YC; Yip J; Wong HH; Leung YY · Craniomaxillofacial trauma & reconstruction · 2025
    Systematic review386 participants8 studies pooledBone Health forMagnesium
  33. Vascularized bone grafting fixed by biodegradable magnesium screw for treating osteonecrosis of the femoral head.
    Zhao D; Huang S; Lu F; Wang B; Yang L; Qin L; Yang K; Li Y; Li W; Wang W; Tian S; Zhang X; Gao W; Wang Z; Zhang Y; Xie X; Wang J; Li J · Biomaterials · 2016
    Randomized trial48 participantsBone Health forMagnesium
  34. An update on magnesium and bone health.
    Rondanelli M; Faliva MA; Tartara A; Gasparri C; Perna S; Infantino V; Riva A; Petrangolini G; Peroni G · Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Narrative reviewBone Health forMagnesium
  35. Sex-specific differences in the association of magnesium intake with femoral neck bone mineral density among older adults.
    Wang B; Tan X; Yao X; Zhu Z · Endocrine connections · 2025
    Cross-sectional study1,343 participantsBone Health forMagnesium
  36. Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies.
    Del Gobbo LC; Imamura F; Wu JH; de Oliveira Otto MC; Chiuve SE; Mozaffarian D · The American journal of clinical nutrition · 2013
    Meta-analysis313,041 participants16 studies pooledCardiovascular Support forMagnesium
  37. Magnesium and the risk of cardiovascular events: a meta-analysis of prospective cohort studies.
    Qu X; Jin F; Hao Y; Li H; Tang T; Wang H; Yan W; Dai K · PloS one · 2013
    Meta-analysis532,979 participants19 studies pooledCardiovascular Support forMagnesium
  38. Quantitative Association Between Serum/Dietary Magnesium and Cardiovascular Disease/Coronary Heart Disease Risk: A Dose-Response Meta-analysis of Prospective Cohort Studies.
    Zhao L; Hu M; Yang L; Xu H; Song W; Qian Y; Zhao M · Journal of cardiovascular pharmacology · 2020
    Meta-analysis544,581 participants18 studies pooledCardiovascular Support Heart Health forMagnesium
  39. Comparative Efficacy of Nutraceuticals on Endothelial Function: A Systematic Review and Network Meta-Analysis.
    Norouzzadeh M; Rashedi MH; Mahdavi-Mazdeh G; Kosari A; Shahinfar H · Current atherosclerosis reports · 2026
    Meta-analysisCardiovascular Support Heart Health forMagnesium
  40. Serum magnesium, mortality, and cardiovascular disease in chronic kidney disease and end-stage renal disease patients: a systematic review and meta-analysis.
    Xiong J; He T; Wang M; Nie L; Zhang Y; Wang Y; Huang Y; Feng B; Zhang J; Zhao J · Journal of nephrology · 2020
    Meta-analysis200,934 participants20 studies pooledCardiovascular Support forMagnesium
  41. Efficacy of oral magnesium therapy in the treatment of chronic constipation in spastic cerebral palsy children: a randomized controlled trial.
    Hassanein SMA; Deifallah SM; Bastawy HA · World journal of pediatrics : WJP · 2021
    Randomized trial100 participantsDigestive Health forMagnesium
  42. Ca:Mg ratio, medium-chain fatty acids, and the gut microbiome.
    Fan L; Zhu X; Sun S; Yu C; Huang X; Ness R; Dugan LL; Shu L; Seidner DL; Murff HJ; Fodor AA; Azcarate-Peril MA; Shrubsole MJ; Dai Q · Clinical nutrition (Edinburgh, Scotland) · 2022
    Randomized trial240 participantsDigestive Health forMagnesium
  43. The Magnesium-Rich Formula for Functional Constipation in Infants: a Randomized Comparator-Controlled Study.
    Benninga MA; MENA Infant Constipation Study Group; Vandenplas Y · Pediatric gastroenterology, hepatology & nutrition · 2022
    Randomized trial286 participantsDigestive Health forMagnesium
  44. A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation.
    Mori S; Tomita T; Fujimura K; Asano H; Ogawa T; Yamasaki T; Kondo T; Kono T; Tozawa K; Oshima T; Fukui H; Kimura T; Watari J; Miwa H · Journal of neurogastroenterology and motility · 2022
    Randomized trial34 participantsDigestive Health forMagnesium
  45. Magnesium treatment increases gut microbiome synthesizing vitamin D and inhibiting colorectal cancer: results from a double-blind precision-based randomized placebo-controlled trial.
    Sun E; Zhu X; Ness RM; Murff HJ; Sun S; Yu C; Fan L; Azcarate-Peril MA; Shrubsole MJ; Dai Q · The American journal of clinical nutrition · 2025
    Randomized trial240 participantsDigestive Health forMagnesium
  46. Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: A randomized controlled trial.
    Hausenblas HA; Lynch T; Hooper S; Shrestha A; Rosendale D; Gu J · Sleep medicine: X · 2025
    Randomized trial80 participantsEnergy forMagnesium
  47. Total magnesium intake and risk of frailty in older women.
    Struijk EA; Fung TT; Bischoff-Ferrari HA; Willett WC; Lopez-Garcia E · Journal of cachexia, sarcopenia and muscle · 2024
    Cohort study81,524 participantsEnergy forMagnesium
  48. Red blood cell magnesium and chronic fatigue syndrome.
    Cox IM; Campbell MJ; Dowson D · Lancet (London, England) · 1991
    Randomized trial32 participantsEnergy forMagnesium
  49. Exercise, magnesium and immune function.
    Laires MJ; Monteiro C · Magnesium research · 2008
    Narrative reviewEnergy forMagnesium
  50. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  51. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  52. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  53. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  54. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  55. Melatonin for preventing and treating jet lag.
    Herxheimer A; Petrie KJ · The Cochrane database of systematic reviews · 2001
    Systematic review10 studies pooledGeneral Health forMelatonin
  56. Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life.
    Schroder CM; Malow BA; Maras A; Melmed RD; Findling RL; Breddy J; Nir T; Shahmoon S; Zisapel N; Gringras P · Journal of autism and developmental disorders · 2019
    Randomized trial125 participantsGeneral Health forMelatonin
  57. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.
    Fatemeh G; Sajjad M; Niloufar R; Neda S; Leila S; Khadijeh M · Journal of neurology · 2022
    Meta-analysis23 studies pooledGeneral Health forMelatonin
  58. Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses.
    Choi K; Lee YJ; Park S; Je NK; Suh HS · Sleep medicine reviews · 2022
    Meta-analysis24 studies pooledGeneral Health forMelatonin
  59. Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial.
    Leerasiri P; Pariyaeksut P; Hengrasmee P; Asumpinwong C · International urogynecology journal · 2023
    Randomized trial60 participantsGeneral Health forMelatonin
  60. Effects of magnesium supplementation on improving hyperglycemia, hypercholesterolemia, and hypertension in type 2 diabetes: A pooled analysis of 24 randomized controlled trials.
    Xu L; Li X; Wang X; Xu M · Frontiers in nutrition · 2023
    Meta-analysis1,325 participants24 studies pooledHeart Health forMagnesium
  61. The effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trial.
    Guerrero-Romero F; Rodríguez-Morán M · Journal of human hypertension · 2009
    Randomized trial82 participantsHeart Health forMagnesium
  62. Positive effects of magnesium supplementation in metabolic syndrome.
    Kisters S; Kisters K; Werner T; Vormann J; Tokmak F; Westhoff T; Gröber U; Predel HG; Reuter H · International journal of clinical pharmacology and therapeutics · 2024
    Randomized trial54 participantsHeart Health forMagnesium
  63. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  64. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  65. The impact of oral melatonin on pain and anxiety reduction during venipuncture in pediatric patients: a double-blind randomized clinical trial.
    Rahafard S; Akbari Jokar Z; Hosseini SA; Alaee E · Annals of medicine and surgery (2012) · 2024
    Randomized trial202 participantsStress Relief forMelatonin
  66. Comparison of Effects of Melatonin and Gabapentin on Post Operative Anxiety and Pain in Lumbar Spine Surgery: A Randomized Clinical Trial.
    Javaherforooshzadeh F; Amirpour I; Janatmakan F; Soltanzadeh M · Anesthesiology and pain medicine · 2022
    Randomized trial90 participantsStress Relief forMelatonin
  67. Melatonin for pre- and postoperative anxiety in adults.
    Hansen MV; Halladin NL; Rosenberg J; Gögenur I; Møller AM · The Cochrane database of systematic reviews · 2015
    Meta-analysis774 participants12 studies pooledStress Relief forMelatonin
  68. Effects of melatonin intake on depression and anxiety in postmenopausal women: a systematic review and meta-analysis of randomised controlled trials.
    Demirhan Kayacik A; İlcioglu K · Archives of women's mental health · 2024
    Meta-analysis441 participants5 studies pooledStress Relief forMelatonin
  69. Premedication effect of melatonin on propofol induction dose for anesthesia, anxiety, orientation and sedation after abdominal surgery: a double-blinded randomized trial.
    Norouzi A; Fateh S; Modir H; Kamali A; Akrami L · Medical gas research · 2020
    Randomized trial88 participantsStress Relief forMelatonin
  70. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsTestosterone Support forMagnesium
  71. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsTestosterone Support forMagnesium
  72. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsTestosterone Support forMagnesium
  73. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledTestosterone Support forMagnesium
  74. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsTestosterone Support forMagnesium
  75. Melatonin potentiates testosterone-induced suppression of luteinizing hormone secretion in normal men.
    Anderson RA; Lincoln GA; Wu FC · Human reproduction (Oxford, England) · 1994
    Randomized trial12 participantsTestosterone Support forMelatonin
  76. Effect of melatonin supplementation on cardiometabolic risk factors, oxidative stress and hormonal profile in PCOS patients: a systematic review and meta-analysis of randomized clinical trials.
    Ziaei S; Hasani M; Malekahmadi M; Daneshzad E; Kadkhodazadeh K; Heshmati J · Journal of ovarian research · 2024
    Meta-analysis6 studies pooledTestosterone Support forMelatonin
  77. Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Mirhosseini N; Kavossian E; Aghadavod E; Bahmani F; Ostadmohammadi V; Kia M; Eftekhar T; Ayati E; Mahdavinia M; Asemi Z · Frontiers in endocrinology · 2020
    Randomized trial56 participantsTestosterone Support forMelatonin
  78. A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol.
    Waldhauser F; Lieberman HR; Lynch HJ; Waldhauser M; Herkner K; Frisch H; Vierhapper H; Waldhäusl W; Schemper M; Wurtman RJ · Neuroendocrinology · 1987
    Clinical trial24 participantsTestosterone Support forMelatonin
  79. Melatonin administered in the afternoon decreases next-day luteinizing hormone levels in men: lack of antagonism by flumazenil.
    Luboshitzky R; Shen-Orr Z; Shochat T; Herer P; Lavie P · Journal of molecular neuroscience : MN · 2000
    Randomized trial6 participantsTestosterone Support forMelatonin