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Bromelain 500 mg

Nutricost
4.7
★ ★ ★ ★ ★
(467 ratings)
Bromelain 500 mg
Product Image
Score79
A substantial 500 mg serving is simple and economical, but weight without enzyme-activity units cannot establish potency.
How scoring works
Quantity:120 Capsule(s) • (120 servings)
Goals:
Digestive Health
Anti-Inflammatory Support

Score 79

A substantial 500 mg serving is simple and economical, but weight without enzyme-activity units cannot establish potency.
How scoring works
$16.95($0.14 per serving)
Vitacost
$ 16.95
iHerb
$ 17.30
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Analysis

The single-active formula supplies 500 mg bromelain in one serving. The absence of GDU, MCU, or other enzyme-activity units leaves potency uncertain despite the substantial weight.

The label identifies a pineapple source. The standard capsule or tablet has no stated acid protection, so delivery for non-digestive use is not specifically optimized.

Timing should match the intended use: a meal-linked serving fits digestive support, while between-meal use is commonly chosen for systemic goals. Value is favorable, and the concise formula makes label assessment easy.

Who is it for
  • Adults seeking a single-ingredient bromelain product
  • People who prefer one active over a large enzyme blend
  • Users not taking medicines that raise bleeding risk
Best for
  • Bromelain supplementation
  • Meal-linked digestive enzyme use
  • A simple enzyme formula

Pros

  • Provides 500 mg bromelain
  • Uses a focused single-active design
  • Avoids unrelated botanical blends
  • Offers favorable value

Cons

  • Does not disclose enzyme-activity units
  • Potency cannot be compared from weight alone
  • Meal-timing directions are not supplied
  • Pineapple source may not suit people with pineapple allergy

Warnings

  • Bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines.
  • Bromelain should be reviewed before a planned procedure because its bleeding effect may be relevant.
  • The pineapple-derived ingredient may be unsuitable for people with pineapple allergy.

Nutrient quality

83 Highest impact

A substantial standalone amount provides useful formula substance. Missing activity units keep the actual enzyme dose uncertain.

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Ingredient transparency

72 High impact

Active weights are listed and no proprietary blend hides the supplied doses. Missing enzyme activity, timing, excipients, and some source details keep disclosure incomplete.

.

Customer satisfaction

68 High impact

A very strong supplied average is supported by a substantial review base. Specific review comments were not provided, so repeated complaints and purpose-specific experiences cannot be assessed.

.

Value for money

94 Highest impact

A substantial amount and very favorable serving cost create strong value. Unknown enzyme activity remains the main limitation.

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Report analysis

Goals

Digestive Health
Digestive Health
Impact
High effect
C+ Goal FitC Strength of SupportD- CoverageA Formula Quality
Bromelain · 500 mg

Bromelain can assist protein digestion and is supplied at a substantial stated weight. Missing enzyme activity units prevent confirmation of actual digestive potency.

The formula remains narrow and does not address fiber, the microbiome, stool regulation, or mucosal repair. Timing guidance is also absent, which matters because use with meals is central to digestive-enzyme support.

Study evidence
Bromelain Supportive 2 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Moderate effect
B Goal FitD+ Strength of SupportD- CoverageA- Formula Quality

Bromelain has a plausible role in reducing swelling and supporting inflammatory balance. The substantial standalone weight makes the formula easy to understand and use.

Enzyme activity is not disclosed, so the listed milligrams do not confirm actual potency. A standard capsule and missing empty-stomach directions also limit confidence in systemic delivery rather than digestive use.

Study evidence
Bromelain Supportive 12 studies

Ingredients

IngredientAmount per serving
Bromelain (Pineapple)
 500 mg
Gluten Free Adults 18–50 Vegetarian
Report overview
Bromelain (Pineapple) · 500 mg OverallScore56
F Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyA+ Value

The full serving provides a substantial amount of bromelain and offers good value for a standalone enzyme. Enzyme activity is not disclosed, so potency cannot be confirmed from the listed weight alone. A standard capsule may be less suitable for systemic use than a delayed-release form, and the available data do not provide clear timing directions.

View ingredientView products
Loading alternative details
86 Performance

Bromelain 2400 GDU/g - 500 mg

NOW
<p>A 500 mg pineapple bromelain serving with clearly stated high activity makes potency easier to assess, improving ingredient clarity and performance compared with Bromelain 500 mg. Meal timing is not stated, and bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines.</p>
83 Performance

High Potency Bromelain 3000 GDU 500 mg

Doctor's Best
<p>A 500 mg serving with clearly disclosed high enzyme activity provides a potent focused option, improving ingredient clarity and performance compared with Bromelain 500 mg. Standard capsule delivery and missing meal timing limit confidence about systemic use.</p>
82 Performance

Bromelain 2400 GDU/g 500 mg

Protocol For Life Balance
<p>A 500 mg pineapple bromelain serving with disclosed high activity provides clear enzyme potency, improving ingredient clarity and performance compared with Bromelain 500 mg. Meal timing is missing, and bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines.</p>
81 Budget

Bromelain 500 mg

AN Amazing Nutrition Amazing Formulas
<p>A lower serving cost makes Bromelain 500 mg an economical alternative to Bromelain 500 mg. A focused 500 mg pineapple bromelain serving keeps the formula simple. Activity units and meal timing are not disclosed, and bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines.</p>
81 Budget

Bromelain 500 mg

The Vitamin Shoppe
<p>A lower serving cost makes Bromelain 500 mg an economical alternative to Bromelain 500 mg. A focused 500 mg pineapple bromelain serving provides a substantial enzyme weight. Activity units and meal timing are not disclosed, and bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines.</p>
74 Budget

Turmeric & Bromelain 450 mg

Natural Factors
<p>A lower serving cost makes Turmeric & Bromelain 450 mg an economical alternative to Bromelain 500 mg. Turmeric and 150 mg of pineapple bromelain broaden the formula beyond a single enzyme. Neither botanical is standardized, and both may increase bleeding tendency with anticoagulant or antiplatelet medicines.</p>
82 Value

Bromelain 500 mg

Natural Factors
<p>A substantial 500 mg pineapple-extract serving combines a focused formula with economical routine use, providing a favorable serving cost relative to Bromelain 500 mg. Activity units and meal timing are not disclosed, so the formula is not fully characterized.</p>
82 Value

Specially-Coated Bromelain 500 mg

Life Extension
<p>A protected tablet and 500 mg of pineapple bromelain support delivery beyond a basic uncoated product, providing stronger ingredient quality for the added cost relative to Bromelain 500 mg. Activity units and meal timing remain undisclosed, so the formula is not fully characterized.</p>
82 Value

Quercetin 880 mg with Bromelain

Nutricost
<p>A substantial quercetin dihydrate amount and 165 mg of bromelain provide broader antioxidant-enzyme coverage, providing stronger ingredient quality for the added cost relative to Bromelain 500 mg. Bromelain activity and source details are missing, so the formula is not fully characterized.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  2. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  3. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support forBromelain
  4. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  5. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  6. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  7. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain