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Bromelain 500 mg

Natural Factors
4.7
★ ★ ★ ★ ★
(2665 ratings)
Bromelain 500 mg
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Score82
A large, affordable bromelain serving is easy to use, but missing activity units prevent a dependable potency comparison.
How scoring works
Quantity:180 Capsule(s) • (180 servings)
Goals:
Digestive Health
Anti-Inflammatory Support

Score 82

A large, affordable bromelain serving is easy to use, but missing activity units prevent a dependable potency comparison.
How scoring works
$25.87($0.14 per serving)
Vitacost
$ 25.87
Amazon
$ 25.87
iHerb
$ 25.87
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Analysis

Bromelain is directly relevant to protein digestion, while systemic use may support short-term swelling and physical comfort. A single-active formula keeps the intended role clear.

Milligrams measure ingredient weight rather than catalytic strength, so the missing GDU or FIP value is an important limitation. The standard capsule and absent timing directions also make systemic delivery less certain.

The large supply minimizes reordering and improves convenience for regular use. The formula fits value-focused users who accept uncertain potency, while careful dose comparison requires an activity-standardized product.

Who is it for
  • Adults seeking a focused bromelain capsule
  • People who want protein-digestion support
  • Value-minded users comfortable with potency uncertainty
Best for
  • Protein-heavy meals
  • Simple enzyme routines
  • Low-cost bromelain use

Pros

  • Substantial ingredient weight
  • Single active ingredient
  • Good practical value

Cons

  • No enzyme activity units
  • No enteric protection
  • No goal-specific timing guidance

Warnings

  • Bromelain may increase bruising or bleeding when combined with anticoagulant or antiplatelet medicines.
  • People planning surgery should ask the surgical team when to stop bromelain because of its effect on bleeding tendency.
  • People with pineapple allergy may also react to pineapple-derived bromelain.

Nutrient quality

79 High impact

A substantial standalone bromelain amount provides a focused enzyme formula. Missing activity units and meal timing make potency and intended delivery harder to judge.

Ingredient transparency

79 High impact

Listed active ingredients have specific amounts and no proprietary blend hides their doses. Bromelain activity, meal timing, full source details, or non-active ingredients remain incompletely disclosed.

Customer satisfaction

74 High impact

The aggregate rating is strong and is supported by a large review sample. No review comments are supplied, so recurring complaints and fit with the intended use cannot be checked.

Value for money

96 Highest impact

The effective serving offers strong value relative to formula quality. A focused or coherent ingredient list supports efficient spending.

Report analysis

Goals

Digestive Health
Impact
High effect
B+ Goal FitC Strength of SupportD CoverageA+ Formula Quality
Bromelain · 500 mg

Bromelain directly supports protein digestion and may help after protein-heavy meals. The 500 mg weight is substantial, but missing activity units prevent a reliable potency estimate.

The focused enzyme does not support fiber intake, the microbiome, or the intestinal barrier. Bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines and can trigger reactions in people allergic to pineapple.

Study evidence
Bromelain Supportive 2 studies
Anti-Inflammatory Support
Impact
High effect
B Goal FitC- Strength of SupportD CoverageA+ Formula Quality

Bromelain provides focused enzyme support that may help with acute tissue swelling and physical discomfort. The 500 mg amount appears substantial, but weight alone cannot show actual enzyme strength.

The one-ingredient design is lean and easy to understand. Missing activity units, pineapple plant part, and use-away-from-meals guidance leave systemic potency and delivery uncertain.

Study evidence
Bromelain Supportive 12 studies

Ingredients

IngredientAmount per serving
Bromelain (Pineapple Extract)
500 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
F Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyA+ Value

The standalone dose is strong and cost efficiency is excellent for the bromelain supplied. Missing activity units make actual enzyme potency uncertain despite the clearly stated weight. The standard capsule provides limited protection for systemic use, and the label data omit meal timing and the pineapple plant part.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  2. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  3. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  4. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support forBromelain
  5. Is bromelain an effective drug for the control of pain and inflammation associated with impacted third molar surgery? Systematic review and meta-analysis.
    de A C Almeida R; de Sousa Lima FCM; do E Vasconcelos BC · International journal of oral and maxillofacial surgery · 2019
    Meta-analysis252 participants5 studies pooledAnti-Inflammatory Support forBromelain
  6. Effect of Oral Administration of Bromelain on Postoperative Discomfort After Third Molar Surgery.
    Ghensi P; Cucchi A; Creminelli L; Tomasi C; Zavan B; Maiorana C · The Journal of craniofacial surgery · 2018
    Randomized trial84 participantsAnti-Inflammatory Support forBromelain
  7. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  8. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  9. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain