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Bromelain 500 mg

AN Amazing Nutrition Amazing Formulas
4.6
★ ★ ★ ★ ★
(156 ratings)
Bromelain 500 mg
Product Image
Score81
Excellent affordability and a large bromelain weight are offset by missing activity units and basic tablet delivery.
How scoring works
Quantity:120 Tablet(s) • (120 servings)
Goals:
Digestive Health
Anti-Inflammatory Support
Joint Health
Immunity

Score 81

Excellent affordability and a large bromelain weight are offset by missing activity units and basic tablet delivery.
How scoring works
$10.98($0.09 per serving)
iHerb
$ 12.99
Pure Formulas
$ 10.98
Vitacost
$ 13.19
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Analysis

The 500 mg weight is directly relevant to protein digestion and may support short-term tissue comfort. A one-active formula avoids padding and makes the ingredient amount easy to see.

No GDU or FIP value is supplied, so functional activity cannot be inferred from the milligram weight. The data also omit pineapple plant-part detail and timing guidance for with-meal versus between-meal use.

The very large supply and unusually low serving cost are the standout benefits. It fits price-sensitive users, while anyone seeking consistent verified potency should select a standardized enzyme.

Who is it for
  • Budget-conscious adults
  • People seeking a single bromelain ingredient
  • Long-term users comfortable with uncertain potency
Best for
  • Low-cost protein-digestion support
  • Simple tablet routines
  • A very long supply

Pros

  • Substantial bromelain weight
  • Single active ingredient
  • Exceptionally low serving cost

Cons

  • No enzyme activity units
  • No enteric coating
  • No meal-timing guidance

Warnings

  • Bromelain may increase bruising or bleeding when combined with anticoagulant or antiplatelet medicines.
  • People planning surgery should ask the surgical team when to stop bromelain because of its effect on bleeding tendency.
  • People with pineapple allergy may also react to pineapple-derived bromelain.

Nutrient quality

79 High impact

A substantial standalone bromelain amount provides a focused enzyme formula. Missing activity units and meal timing make potency and intended delivery harder to judge.

Ingredient transparency

79 High impact

Listed active ingredients have specific amounts and no proprietary blend hides their doses. Bromelain activity, meal timing, full source details, or non-active ingredients remain incompletely disclosed.

Customer satisfaction

67 High impact

The aggregate rating is favorable and is supported by a limited review sample. No review comments are supplied, so recurring complaints and fit with the intended use cannot be checked.

Value for money

98 Highest impact

The effective serving offers strong value relative to formula quality. A focused or coherent ingredient list supports efficient spending.

Report analysis

Goals

Digestive Health
Impact
High effect
C+ Goal FitC+ Strength of SupportD+ CoverageA Formula Quality
Bromelain · 500 mg

Bromelain at 500 mg is directly relevant to protein digestion and provides a substantial enzyme weight. The label does not state enzyme activity units, so actual digestive potency cannot be verified.

The single-active tablet is focused but does not address fiber, motility, microbiome, or mucosal support. Bromelain may increase bleeding tendency when combined with anticoagulant or antiplatelet medicines.

Study evidence
Bromelain Supportive 2 studies
Anti-Inflammatory Support
Impact
High effect
C+ Goal FitC Strength of SupportD+ CoverageA+ Formula Quality

Bromelain may help break down proteins involved in swelling and tissue irritation. Human evidence is situation specific and depends on enzyme activity and timing away from food.

The milligram amount is substantial, but enzyme activity units are not disclosed. Bromelain may increase bruising risk when combined with anticoagulant or antiplatelet medicines.

Study evidence
Bromelain Supportive 12 studies
Joint Health
Impact
Moderate effect
C- Goal FitD+ Strength of SupportD- CoverageA Formula Quality

Bromelain may support joint comfort through proteolytic and inflammatory pathways, and the listed weight is substantial. Enzyme activity is not provided in GDU or FIP units, so functional potency cannot be determined from milligrams alone.

The single-enzyme formula has reasonable depth but does not support cartilage structure or lubrication. Its clean design is useful for focused use, though evidence is less established than for core joint ingredients.

Study evidence
Bromelain Mixed 5 studies
Immunity
Impact
Moderate effect
D Goal FitC+ Strength of SupportF CoverageB+ Formula Quality

Bromelain may help with sinus swelling and mucus during some upper-respiratory problems, but it does not broadly support immune-cell readiness. Its role is therefore situational rather than foundational.

The listed weight is substantial, yet the label omits enzyme-activity units needed to judge potency. Bromelain may increase bleeding tendency with anticoagulant or antiplatelet medicines, which is a practical ingredient-specific caution.

Study evidence
Bromelain Not classified 1 study

Ingredients

IngredientAmount per serving
Bromelain (Pineapple)
500 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
F Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyA+ Value

The standalone formula supplies a full bromelain amount at a very low cost, but the label omits enzyme activity. A standard tablet offers limited protection for systemic use, and no timing guidance is provided. Pineapple is named without the stem source, so source detail remains incomplete despite excellent dose efficiency.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsAnti-Inflammatory Support forBromelain
  2. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledAnti-Inflammatory Support forBromelain
  3. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsAnti-Inflammatory Support Immunity forBromelain
  4. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsAnti-Inflammatory Support forBromelain
  5. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewAnti-Inflammatory Support forBromelain
  6. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  7. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain
  8. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
    Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
    Narrative reviewJoint Health forBromelain
  9. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
    Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
    Randomized trial40 participantsJoint Health forBromelain
  10. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsJoint Health forBromelain
  11. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
    Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
    Meta-analysis697 participants6 studies pooledJoint Health forBromelain
  12. The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
    Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
    Randomized trial150 participantsJoint Health forBromelain