Benfotiamine 150 mg
Doctor's Best
Benfotiamine 150 mg
4.7
★ ★ ★ ★ ★
(5249 ratings)
Thiamin 150 mg
Leucine 12 mg
Score 90.0
An excellent long-term value for high-bioavailability Benfotiamine at a standard 150mg dose, primarily supporting nerve and metabolic health with a large supply.
Quantity: 360 Veggie Cap(s)Servings size: 1 Veggie Capsule(s) (360 servings)
Selected goals:
Other goals:
Energy
Brain Health
Cognitive Support
Cardiovascular Support
Testosterone Support
leaderboard Score 90.0
An excellent long-term value for high-bioavailability Benfotiamine at a standard 150mg dose, primarily supporting nerve and metabolic health with a large supply.
insights Analysis
This is a high-volume offering of Doctor's Best Benfotiamine 150 mg, providing 360 servings of the fat-soluble Vitamin B1 derivative. Its primary purpose is to support nerve health, regulate glucose metabolism, and enhance cellular energy. The extended supply at a very low cost per serving makes it highly economical for individuals requiring long-term or consistent Benfotiamine supplementation. The 12mg of L-Leucine remains an insignificant component, not contributing to functional benefits.
- Offers highly bioavailable Benfotiamine for superior absorption.
- Exceptional price per serving (11 cents) due to large volume.
- Provides 360 servings, ideal for long-term, consistent use.
- From a reputable brand, ensuring quality and trust.
- The 12mg of L-Leucine is an irrelevant inclusion for any stated goals.
- Only offers Benfotiamine, without synergistic compounds like Alpha-Lipoic Acid.
$39.82($0.11 per serving)
 Amazon | $ 39.82 | |
 iHerb | $ 41.58 | |
 Vitacost | $ 43.99 |
bolt Effectiveness for goals
Leucine is an essential branched-chain amino acid (BCAA) primarily known for its critical role in stimulating muscle protein synthesis (MPS). It acts as a signaling molecule, initiating the molecular pathways necessary for muscle growth and repair. This makes it crucial for maintaining and building muscle mass.
Leucine is a crucial branched-chain amino acid (BCAA) that acts as a potent stimulator of muscle protein synthesis (MPS). It activates the mTOR pathway, a key regulator of muscle growth and repair. This makes it particularly important for individuals looking to build or maintain muscle mass.
Thiamin, or vitamin B1, is crucial for converting carbohydrates into energy, supporting the metabolism of glucose, amino acids, and lipids. It plays an essential role in numerous cellular functions, particularly nerve and muscle function. This makes it vital for energy production and overall cell health.
Leucine plays a significant role in reducing muscle protein breakdown and promoting muscle protein synthesis, both essential processes for recovery. Supplementing with leucine after exercise may help decrease muscle soreness and accelerate the repair of muscle tissue. This contributes to faster recovery and readiness for subsequent training.
Thiamin is crucial for converting carbohydrates into energy and plays a vital role in nerve function, muscle contraction, and heart health. It acts as a coenzyme in metabolic reactions essential for glucose metabolism. Maintaining adequate thiamin levels supports overall cellular energy production.
schedule Dosage, timing & forms
The recommended daily allowance (RDA) for thiamin for adult men is 1.2 mg per day, and for adult women, it is 1.1 mg per day. These recommendations are designed to meet the nutritional needs of most healthy individuals. Pregnant and lactating women may have slightly higher requirements.
Leucine is often recommended to be taken around workouts, particularly before or after, to help optimize muscle protein synthesis. It can also be beneficial between meals, especially if dietary protein intake is low. Spreading intake throughout the day can help maintain elevated leucine levels.
Yes, consuming Leucine immediately before, during, or after resistance exercise is a common strategy to maximize muscle protein synthesis. Some research suggests that consistent Leucine intake throughout the day, particularly during periods between meals, may also be beneficial. The 'Leucine threshold' concept highlights the importance of consuming a sufficient amount to trigger synthesis.
Thiamin is found in various foods, including whole grains, fortified cereals, pork, fish, and legumes. Nuts, seeds, and certain vegetables like peas and asparagus also contribute to dietary thiamin intake. A balanced diet typically provides sufficient thiamin for most individuals.
For muscle protein synthesis, common effective doses of Leucine range from 2.5 to 5 grams per serving. Doses are often part of a larger essential amino acid (EAA) or branched-chain amino acid (BCAA) supplement blend. Individual needs can vary based on activity level and dietary protein intake.
health_and_safety Safety & interactions
Yes, certain medications may interact with Thiamin. Diuretics, particularly loop diuretics, can increase Thiamin excretion, potentially leading to deficiency. Some chemotherapy agents may also interfere with Thiamin metabolism. It's advisable to consult a healthcare professional if you are taking medications.
Thiamin is water-soluble, and excess amounts are typically excreted in the urine. Due to this, adverse effects from oral thiamin supplementation are rare, even at high doses. In very rare cases, extremely high intravenous doses have been associated with allergic reactions.
Chronic alcohol consumption can significantly impair Thiamin absorption and utilization, often leading to Thiamin deficiency. While alcohol does not make Thiamin supplementation unsafe, individuals who consume alcohol regularly may require higher Thiamin intake. Supplementation is often crucial for alcoholics to prevent or treat deficiency-related complications.
Thiamin is generally considered safe when taken at recommended doses, and side effects are rare. In very high doses or with intravenous administration, some individuals might experience mild upset stomach or allergic reactions, though these are uncommon. Oral supplementation typically does not cause adverse effects.
Thiamin is a water-soluble vitamin, so excess amounts are typically excreted through urine. Acute toxicity from oral Thiamin supplementation is extremely rare and has not been reported even at very high doses. However, excessively high intravenous doses could potentially lead to adverse effects, though this is not relevant for oral supplements.
Ingredients
| Ingredient | Amount per serving |
|---|---|
| Benfotiamine | 150 mg |
| L-Leucine | 12 mg |
Categories
Thiamin 95.0
This product contains Benfotiamine, a highly absorbable and fat-soluble form of Thiamin (Vitamin B1). Its superior bioavailability allows for more effective delivery to tissues compared to conventional thiamine, making it an excellent source.
Leucine 10.0
The 12mg of L-Leucine is a functionally insignificant amount and does not contribute to the typical benefits associated with Leucine, such as muscle protein synthesis or recovery, which require much higher, gram-level dosages.
Goals
Metabolism Boost 90.0
Benfotiamine plays a crucial role in glucose metabolism, helping to reduce the formation of harmful advanced glycation end-products (AGEs). This action significantly supports healthy metabolic function and glucose regulation.
Energy 85.0
Benfotiamine's role in glucose metabolism and energy production pathways makes it effective for supporting overall cellular energy. Its sustained use can help maintain consistent energy levels.
Brain Health 85.0
As a fat-soluble form of B1, Benfotiamine efficiently crosses the blood-brain barrier to protect neuronal cells from metabolic stress and support their healthy function, contributing significantly to brain health.
Recommended Alternatives
80 Value 
B-Complex '100'
Solgar
4.7
★★★★★
(15200 ratings)
This comprehensive B-complex provides 100mg of Thiamine, along with high doses of other essential B vitamins, for a reasonable price per serving (15 cents). It offers a broader spectrum of B vitamin benefits, making it a better value for overall metabolic support.
78 Value 
B-Complex 50
Solaray
4.7
★★★★★
(6795 ratings)
Offering 50mg of Thiamine along with a full spectrum of B vitamins for 13 cents per serving, this B-complex provides good value for a comprehensive nutritional foundation. It supports general metabolism and energy more broadly than a single ingredient.
85 Value 
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
This multivitamin includes 75mg of Thiamine as part of a highly comprehensive formula packed with numerous vitamins, minerals, and other beneficial compounds for 15 cents per serving. It offers exceptional overall nutritional value beyond just B1.
80 Performance 
Benfotiamine + Alpha Lipoic Acid
California Gold Nutrition
4.7
★★★★★
(3443 ratings)
This alternative combines Benfotiamine with Alpha-Lipoic Acid, offering a synergistic blend for enhanced nerve and metabolic support, which the single-ingredient original lacks. The addition of ALA can provide broader antioxidant benefits.
85 Performance 
Benfotiamine 150 + Alpha-Lipoic Acid 300
Doctor's Best
4.6
★★★★★
(2237 ratings)
This product, from the same brand, adds 300mg of Alpha-Lipoic Acid to the 150mg Benfotiamine. This combination is 'better' for comprehensive nerve health and blood sugar management due to ALA's potent antioxidant and metabolic benefits.
80 Performance 
Benfotiamine 150 mg
California Gold Nutrition
4.7
★★★★★
(3286 ratings)
While the same Benfotiamine dose, this alternative is a different brand, offering a comparable quality Benfotiamine product. It presents a 'better' option for brand diversification or if a user prefers California Gold Nutrition's formulation.
68 Budget 
B 50 Complex
Thompson
4.7
★★★★★
(2864 ratings)
This B-complex offers 50mg of standard Thiamine at a lower price per serving (8 cents vs 11 cents) while also providing other B vitamins. It's a more economical choice for general B1 needs, though less bioavailable than Benfotiamine.
69 Budget 
B-50 Complex
21st Century
4.7
★★★★★
(8446 ratings)
Offering 50mg of Thiamine per serving for 8 cents, this B-complex provides a good array of B vitamins at a cheaper unit cost than the original. It's a cost-effective option for broad B vitamin support, though not Benfotiamine.
72 Budget 
B-1 100 mg
Source Naturals
4.8
★★★★★
(955 ratings)
This product delivers 100mg of standard Vitamin B1 per serving for just 6 cents, making it significantly cheaper. It's a straightforward and budget-friendly choice for supplementing Thiamine, though it lacks the advanced bioavailability of Benfotiamine.
80 Value
B-Complex '100'
Solgar
4.7
★★★★★
(15200 ratings)
This comprehensive B-complex provides 100mg of Thiamine, along with high doses of other essential B vitamins, for a reasonable price per serving (15 cents). It offers a broader spectrum of B vitamin benefits, making it a better value for overall metabolic support.
78 Value
B-Complex 50
Solaray
4.7
★★★★★
(6795 ratings)
Offering 50mg of Thiamine along with a full spectrum of B vitamins for 13 cents per serving, this B-complex provides good value for a comprehensive nutritional foundation. It supports general metabolism and energy more broadly than a single ingredient.
85 Value
Two-Per-Day Capsules
Life Extension
4.7
★★★★★
(85932 ratings)
This multivitamin includes 75mg of Thiamine as part of a highly comprehensive formula packed with numerous vitamins, minerals, and other beneficial compounds for 15 cents per serving. It offers exceptional overall nutritional value beyond just B1.
80 Performance
Benfotiamine + Alpha Lipoic Acid
California Gold Nutrition
4.7
★★★★★
(3443 ratings)
This alternative combines Benfotiamine with Alpha-Lipoic Acid, offering a synergistic blend for enhanced nerve and metabolic support, which the single-ingredient original lacks. The addition of ALA can provide broader antioxidant benefits.
85 Performance
Benfotiamine 150 + Alpha-Lipoic Acid 300
Doctor's Best
4.6
★★★★★
(2237 ratings)
This product, from the same brand, adds 300mg of Alpha-Lipoic Acid to the 150mg Benfotiamine. This combination is 'better' for comprehensive nerve health and blood sugar management due to ALA's potent antioxidant and metabolic benefits.
80 Performance
Benfotiamine 150 mg
California Gold Nutrition
4.7
★★★★★
(3286 ratings)
While the same Benfotiamine dose, this alternative is a different brand, offering a comparable quality Benfotiamine product. It presents a 'better' option for brand diversification or if a user prefers California Gold Nutrition's formulation.