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Immune

4.8
★ ★ ★ ★ ★
(223 ratings)
Vitamin C 501 mg
Saccharomyces cerevisiae 500 mg
Product Image
Score63
Broad immune-support coverage is useful, but probiotic opacity, unbuffered vitamin C, and weak value hold it back.
How scoring works
Tablet
Quantity:60 Tablet(s) • (30 servings)
Goals:
Anti-Inflammatory Support
Immunity
General Health
Skin Health

Score 63

Broad immune-support coverage is useful, but probiotic opacity, unbuffered vitamin C, and weak value hold it back.
How scoring works
$29.99($0.99 per serving)
iHerb
$ 29.99
Pure Formulas
$ 29.99
Pure Formulas
$ 29.99
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Analysis

The formula combines vitamin C with zinc, EpiCor yeast fermentate, echinacea, prebiotic fiber, and probiotics for broad immune-focused support. Several meaningful ingredient amounts are disclosed, giving the product more depth than a basic vitamin C tablet.

Vitamin C includes an unbuffered ascorbic acid component, which may be less comfortable for sensitive stomachs. The probiotic blend does not show a useful quantity in the supplied data, so its practical contribution cannot be judged.

A two-tablet serving and relatively high ongoing cost reduce convenience and value. EpiCor and echinacea make the product more specialized, but they also make it a poor fit for shoppers who only need vitamin C or zinc.

Who is it for
  • Adults wanting a multi-pathway immune formula
  • Users interested in EpiCor and echinacea
  • People who prefer an all-in-one tablet blend
Best for
  • Broad immune-support routines
  • Combined vitamin C and zinc intake
  • Yeast-fermentate and botanical support

Pros

  • Useful vitamin C and zinc amounts
  • Full EpiCor amount is stated
  • Includes echinacea and prebiotic fiber
  • Broad formula without a very long ingredient list

Cons

  • Probiotic quantity and strains are unclear
  • Contains unbuffered ascorbic acid
  • Two tablets per serving
  • Weak value for ongoing use

Warnings

  • People avoiding yeast-derived ingredients should note the substantial Saccharomyces cerevisiae fermentate.
  • The unbuffered ascorbic acid component may cause stomach discomfort in sensitive users.

Nutrient quality

76 High impact

Zinc chelate is favorable, while several other forms and strain details are missing. Vitamin C, zinc, and yeast fermentate are meaningful, but probiotic potency cannot be judged.

.

Ingredient transparency

54 Moderate impact

Most actives have amounts, but the probiotic blend is listed without usable potency. A complete excipient list is not available in the supplied data.

.

Customer satisfaction

74 High impact

The average rating is very strong. The rating volume is adequate for a useful satisfaction signal.

.

Value for money

50 Lower impact

The short supply makes each serving relatively costly. Opaque probiotics and small extras weaken practical value.

.
Report analysis

Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
C+ Goal FitB+ Strength of SupportB- CoverageC+ Formula Quality
Vitamin E · 5 mgVitamin C · 501 mg

Vitamin C, vitamin E, zinc, and the time-release design provide broad antioxidant and immune support relevant to inflammatory balance. EpiCor, echinacea, and probiotics add several immune-focused mechanisms.

The formula is designed mainly for immune support, and individual probiotic strains or amounts are not disclosed. Unbuffered vitamin C may also be less comfortable for sensitive stomachs despite the sustained-release tablet.

Study evidence
Vitamin C Supportive 50 studies
Vitamin E Supportive 20 studies
Zinc Supportive 64 studies
Immunity
Immunity
Impact
High effect
B+ Goal FitC+ Strength of SupportB CoverageC+ Formula Quality
Magnesium · 3 mgVitamin C · 501 mgZinc · 10 mg

Vitamin C, zinc, EpiCor, echinacea, and a probiotic blend address antioxidant, cellular, and gut-linked immune pathways. Vitamin C meets the minimum target, while zinc is useful but below the preferred primary amount.

The probiotic blend lacks strain identities and counts, which limits confidence in its contribution. Echinacea is meaningfully disclosed, but the formula's strongest evidence still comes from vitamin C and zinc.

Study evidence
Vitamin C Supportive 53 studies
Zinc Supportive 73 studies
General Health
General Health
Impact
High effect
B Goal FitB- Strength of SupportC+ CoverageC+ Formula Quality
Magnesium · 3 mgZinc · 10 mgVitamin C · 501 mg

Vitamin C and chelated zinc provide established antioxidant and immune-related nutritional support. Vitamin E, EpiCor, echinacea, prebiotic fiber, and probiotics broaden the formula beyond two core nutrients.

The probiotic blend lacks an organism count and strain details, and several supporting ingredients have modest or unclear amounts. These gaps make the formula less dependable as a broad daily-health product despite its useful vitamin C and zinc foundation.

Study evidence
Vitamin C Supportive 56 studies
Zinc Supportive 60 studies
Skin Health
Skin Health
Impact
High effect
C Goal FitB- Strength of SupportB- CoverageC Formula Quality
Zinc · 10 mgVitamin C · 501 mgVitamin E · 5 mg

Vitamin C and zinc support collagen synthesis, repair, and antioxidant defense, giving this immune formula some genuine skin relevance. EpiCor, echinacea, probiotics, and prebiotic fiber mainly serve immune or digestive goals rather than direct skin outcomes.

The main vitamin and zinc amounts are clear, but the probiotic blend is undisclosed and several minerals are token amounts. The formula is broad yet only moderately deep for skin because it lacks collagen, hyaluronic acid, or a strong photo-protective active.

Study evidence
Vitamin C Supportive 53 studies
Zinc Supportive 66 studies
Vision Support
Vision Support
Impact
Moderate effect
C+ Goal FitC+ Strength of SupportC- CoverageD- Formula Quality
Zinc · 10 mgVitamin E · 5 mgVitamin C · 501 mg

Vitamin C supplies relevant antioxidant support, while 10 mg zinc and 5 mg vitamin E add limited complementary coverage. These nutrients overlap with established vision formulas, but the amounts and immune-focused design do not closely reproduce them.

Time-release delivery is useful for vitamin C, yet the probiotic blend, EpiCor, echinacea, and prebiotic fiber add little direct value for the eyes. The formula lacks lutein, zeaxanthin, and omega-3 fats, so breadth remains centered on general antioxidant support.

Study evidence
Vitamin C Disputed 24 studies
Vitamin E Disputed 35 studies
Zinc Supportive 39 studies

Ingredients

IngredientAmount per serving
Total Carbohydrates
1 Gram(s)
Vitamin C (Acerola Cherry, Ascorbic Acid)
 501 mg
Vitamin E
5 mg
Calcium
16 mg
Phosphorus
6 mg
Magnesium
3 mg
Zinc (Zinc Amino Acid Chelate)
 10 mg
Sodium
15 mg
Potassium
34 mg
Proprietary Probiotic Blend
0 NP
EpiCor (Saccharomyces cerevisiae)
 500 mg
Echinacea purpurea Aerial Extract
100 mg
Fructooligosaccharides
50 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Report overview
Vitamin C (Acerola Cherry, Ascorbic Acid) · 501 mg OverallScore69
C Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The stated vitamin C amount falls in an efficient range, and time-release tablets may extend delivery across the day. The ascorbic acid is not buffered, so people with a sensitive stomach may find it less comfortable than a mineral ascorbate. Cost per gram is high despite the useful dose and clear mineral amounts.

View ingredientView products
Loading alternative details
89 Performance

Pure Buffered Calcium Ascorbate

NOW
<p>Buffered calcium ascorbate supplies a meaningful vitamin C amount with clearer dosing and better digestive comfort than plain ascorbic acid. The formula is narrower than the original, but it avoids the zero-quantity probiotic blend and opaque strain profile.</p>
85 Performance

EpiCor Dried Yeast Fermentate 500 mg

California Gold Nutrition
<p>A clearly identified 500 mg EpiCor serving directly preserves one of the original's principal immune-oriented ingredients. It lacks vitamin C, zinc, echinacea, and probiotics, yet its focused disclosure is much easier to assess than the original's ambiguous blend.</p>
87 Performance

Ester-C Plus 1000 mg Vitamin C

Solgar
<p>Buffered vitamin C with citrus bioflavonoids provides a transparent, focused alternative with strong form quality. It sacrifices the original's broader ingredient list, but removes the unclear probiotic dosing and short-supply trade-off.</p>
87 Budget

100% Pure Vitamin C Powder

Swanson Premium Brand
<p>Pure ascorbic acid provides a flexible, meaningful vitamin C serving at a small fraction of the original's recurring cost. It omits zinc, echinacea, yeast fermentate, and probiotics, but also avoids the original's zero-quantity probiotic blend and missing strain doses.</p>
88 Budget

Sodium Ascorbate Capsules

NutriBiotic Immunity
<p>Buffered vitamin C offers clear dosing and gentler acidity with much stronger serving value than the original multi-active tablet. The sodium contribution matters for restricted diets, while the focused label avoids the original's unresolved probiotic quantities.</p>
83 Budget

EpiCor 500 mg

Healthy Origins
<p>Branded EpiCor preserves the original's 500 mg yeast fermentate in a much simpler and less costly formula. It does not include vitamin C, zinc, echinacea, or probiotics, but the main yeast-derived active is clearly identified.</p>
89 Value

C-500 Calcium Ascorbate-C

NOW
<p>Buffered calcium ascorbate delivers practical vitamin C with clear mineral disclosure and exceptional serving value. The small bioflavonoid addition contributes little, but the formula is far more transparent than the original's zero-quantity probiotic blend.</p>
86 Value

Ester-C 500 mg With Citrus Bioflavoinds

American Health
<p>Buffered Ester-C and citrus bioflavonoids provide a coherent vitamin C formula at substantially better value. The option is narrower than the original, yet its disclosed actives avoid uncertainty about probiotic strains and quantities.</p>
88 Value

Buffered Gold C

California Gold Nutrition
<p>Buffered sodium ascorbate supplies a substantial vitamin C serving in a simple, economical formula. Sodium-restricted users should count its contribution, while the clear active profile improves on the original's opaque probiotic component.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  2. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  3. The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.
    SeyedAlinaghi S; Shahidi R; Mojdeganlou H; Akhtaran FK; Maroufi SF; Maroufi SP; Mirzapour P; Karimi A; Khodaei S; Pour MM; Mehraeen E; Dadras O · Journal of health, population, and nutrition · 2024
    Systematic review28 studies pooledImmunity forVitamin C
  4. Vitamin C supplementation and salivary immune function following exercise-heat stress.
    Carrillo AE; Murphy RJ; Cheung SS · International journal of sports physiology and performance · 2009
    Randomized trial12 participantsImmunity forVitamin C
  5. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  6. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  7. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  8. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  9. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  10. Effects of delta-tocotrienol supplementation on Glycemic Control, oxidative stress, inflammatory biomarkers and miRNA expression in type 2 diabetes mellitus: A randomized control trial.
    Mahjabeen W; Khan DA; Mirza SA; Pervez MA · Phytotherapy research : PTR · 2021
    Randomized trial110 participantsAnti-Inflammatory Support forVitamin E
  11. Effect of vitamin E supplementation on serum C-reactive protein level: a meta-analysis of randomized controlled trials.
    Saboori S; Shab-Bidar S; Speakman JR; Yousefi Rad E; Djafarian K · European journal of clinical nutrition · 2016
    Meta-analysis495 participants12 studies pooledAnti-Inflammatory Support forVitamin E
  12. Efficacy of Nutritional Interventions on Inflammatory Markers in Haemodialysis Patients: A Systematic Review and Limited Meta-Analysis.
    Khor BH; Narayanan SS; Sahathevan S; Gafor AHA; Daud ZAM; Khosla P; Sabatino A; Fiaccadori E; Chinna K; Karupaiah T · Nutrients · 2018
    Meta-analysis46 studies pooledAnti-Inflammatory Support forVitamin E
  13. Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
    Chee NM; Sinnanaidu RP; Chan WK · Journal of gastroenterology and hepatology · 2024
    Meta-analysis8 studies pooledAnti-Inflammatory Support forVitamin E
  14. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial.
    Pervez MA; Khan DA; Slehria AUR; Ijaz A · Complementary therapies in medicine · 2021
    Randomized trial71 participantsAnti-Inflammatory Support forVitamin E
  15. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent.
    Bao B; Prasad AS; Beck FW; Fitzgerald JT; Snell D; Bao GW; Singh T; Cardozo LJ · The American journal of clinical nutrition · 2010
    Randomized trial40 participantsAnti-Inflammatory Support forZinc
  16. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis.
    Nazari M; Nikbaf-Shandiz M; Pashayee-Khamene F; Bagheri R; Goudarzi K; Hosseinnia NV; Dolatshahi S; Omran HS; Amirani N; Ashtary-Larky D; Asbaghi O; Ghanavati M · Biological trace element research · 2024
    Meta-analysis23 studies pooledAnti-Inflammatory Support forZinc
  17. The Effects of Zinc Supplementation on C-Reactive Protein and Inflammatory Cytokines: A Meta-Analysis and Systematical Review.
    Ceylan MN; Akdas S; Yazihan N · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Meta-analysis73 studies pooledAnti-Inflammatory Support forZinc
  18. The Effects of Zinc Sulfate Supplementation on Serum Copeptin, C-Reactive Protein and Metabolic Markers in Zinc-Deficient Diabetic Patients on Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Hosseini R; Montazerifar F; Shahraki E; Karajibani M; Mokhtari AM; Dashipour AR; Ferns GA; Jalali M · Biological trace element research · 2021
    Randomized trial46 participantsAnti-Inflammatory Support forZinc
  19. Zinc supplementation and cardiovascular disease risk factors: A GRADE-assessed systematic review and dose-response meta-analysis.
    Nazari M; Ashtary-Larky D; Nikbaf-Shandiz M; Goudarzi K; Bagheri R; Dolatshahi S; Omran HS; Amirani N; Ghanavati M; Asbaghi O · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Meta-analysis75 studies pooledAnti-Inflammatory Support forZinc
  20. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  21. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  22. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  23. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  24. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  25. Effectiveness of sodium bicarbonate and zinc chloride mouthwashes in the treatment of oral mucositis and quality of life in patients with cancer under chemotherapy.
    Mohammadi F; Oshvandi K; Kamallan SR; Khazaei S; Ranjbar H; Ahmadi-Motamayel F; Gillespie M; Jenabi E; Vafaei SY · Nursing open · 2022
    Randomized trial144 participantsGeneral Health forZinc
  26. Zinc supplementation in young children with acute diarrhea in India.
    Sazawal S; Black RE; Bhan MK; Bhandari N; Sinha A; Jalla S · The New England journal of medicine · 1995
    Randomized trial937 participantsGeneral Health forZinc
  27. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13.
    Clemons TE; Kurinij N; Sperduto RD; AREDS Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2004
    Randomized trial4,753 participantsGeneral Health forZinc
  28. Effects of zinc and probiotic co-supplementation on inflammation, gastrointestinal symptoms, quality of life, and mood in irritable bowel syndrome patients.
    Rezazadegan M; Soheilipour M; Amani R · Scientific reports · 2026
    Randomized trial84 participantsGeneral Health forZinc
  29. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial.
    Siahbazi S; Behboudi-Gandevani S; Moghaddam-Banaem L; Montazeri A · The journal of obstetrics and gynaecology research · 2018
    Randomized trial142 participantsGeneral Health forZinc
  30. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  31. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  32. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  33. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  34. Nutrient supplementation for prevention of viral respiratory tract infections in healthy subjects: A systematic review and meta-analysis.
    Vlieg-Boerstra B; de Jong N; Meyer R; Agostoni C; De Cosmi V; Grimshaw K; Milani GP; Muraro A; Oude Elberink H; Pali-Schöll I; Roduit C; Sasaki M; Skypala I; Sokolowska M; van Splunter M; Untersmayr E; Venter C; O'Mahony L; Nwaru BI · Allergy · 2022
    Meta-analysis199,055 participants115 studies pooledImmunity forZinc
  35. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial.
    Sazawal S; Black RE; Jalla S; Mazumdar S; Sinha A; Bhan MK · Pediatrics · 1998
    Randomized trial609 participantsImmunity forZinc
  36. A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children.
    Rerksuppaphol S; Rerksuppaphol L · Pediatric reports · 2020
    Randomized trial64 participantsImmunity forZinc
  37. The effect of zinc and vitamin A supplementation on immune response in an older population.
    Fortes C; Forastiere F; Agabiti N; Fano V; Pacifici R; Virgili F; Piras G; Guidi L; Bartoloni C; Tricerri A; Zuccaro P; Ebrahim S; Perucci CA · Journal of the American Geriatrics Society · 1998
    Randomized trial136 participantsImmunity forZinc
  38. The role of specific nutrients in preventing immune system and blood cell disorders: an umbrella review.
    Vecchietti A; Strano P; Minutolo G; Grieco V; Cappuccio G; Granvillano G; Confalonieri L; Briganti GL; Raso E; Chimienti M; Pellegrini M; Mercogliano M; Spatari G; Lugli C; Urbano T; Lorenzon A · Journal of preventive medicine and hygiene · 2026
    Systematic review13 studies pooledImmunity forZinc
  39. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  40. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  41. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  42. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  43. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  44. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  45. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  46. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  47. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  48. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc
  49. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  50. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  51. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  52. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C Vision Support forVitamin E
  53. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C
  54. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2018
    Meta-analysis55,614 participants4 studies pooledVision Support forVitamin E
  55. Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study.
    Christen WG; Liu S; Glynn RJ; Gaziano JM; Buring JE · Archives of ophthalmology (Chicago, Ill. : 1960) · 2008
    Cohort study35,551 participantsVision Support forVitamin E
  56. Long-term nutrient intake and 5-year change in nuclear lens opacities.
    Jacques PF; Taylor A; Moeller S; Hankinson SE; Rogers G; Tung W; Ludovico J; Willett WC; Chylack LT · Archives of ophthalmology (Chicago, Ill. : 1960) · 2005
    Cohort study408 participantsVision Support forVitamin E
  57. Dietary intake of antioxidants and risk of age-related macular degeneration.
    van Leeuwen R; Boekhoorn S; Vingerling JR; Witteman JC; Klaver CC; Hofman A; de Jong PT · JAMA · 2005
    Cohort study4,765 participantsVision Support forVitamin E
  58. Antioxidant vitamin and mineral supplements for age-related macular degeneration.
    Evans JR · The Cochrane database of systematic reviews · 2002
    Systematic review170 participants7 studies pooledVision Support forZinc
  59. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
    Evans JR; Lawrenson JG · The Cochrane database of systematic reviews · 2023
    Meta-analysis3,790 participants5 studies pooledVision Support forZinc
  60. Oral zinc in macular degeneration.
    Newsome DA; Swartz M; Leone NC; Elston RC; Miller E · Archives of ophthalmology (Chicago, Ill. : 1960) · 1988
    Randomized trial151 participantsVision Support forZinc
  61. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
    Age-Related Eye Disease Study Research Group · Archives of ophthalmology (Chicago, Ill. : 1960) · 2001
    Randomized trial3,640 participantsVision Support forZinc
  62. Effect of vitamin A and zinc supplementation on the nutriture of children in Northeast Thailand.
    Udomkesmalee E; Dhanamitta S; Sirisinha S; Charoenkiatkul S; Tuntipopipat S; Banjong O; Rojroongwasinkul N; Kramer TR; Smith JC · The American journal of clinical nutrition · 1992
    Randomized trial133 participantsVision Support forZinc