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Ester-C Plus 1000 mg Vitamin C

Solgar
4.9
★ ★ ★ ★ ★
(780 ratings)
Vitamin C 1000 mg
Flavonoid (mixture) 200 mg
Product Image
Score86
A long-supply, high-potency Ester-C formula is transparent and convenient, but its fixed large amount offers limited dosing flexibility.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
General Health
Skin Health
Immunity
Anti-Inflammatory Support
Vision Support

Score 86

A long-supply, high-potency Ester-C formula is transparent and convenient, but its fixed large amount offers limited dosing flexibility.
How scoring works

Also available as

1 option
50 servings Flavonoid (mixture) 200 mg, C 1000 mg • 50 Capsule(s) • 50 servings $14.24 ($0.28 per serving)
$27.74($0.27 per serving)
iHerb
$ 27.74
iHerb
$ 27.74
Daily Vita
$ 27.74
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Analysis

A substantial vitamin C amount comes from buffered Ester-C, which should be gentler than plain ascorbic acid for many people. The one-capsule serving suits users who want high potency without multiple pills.

Calcium is stated separately, making the mineral contribution transparent. Citrus bioflavonoids add useful complementary compounds while keeping the ingredient list focused.

The larger package supports consistent long-term use and good dose-adjusted value. People with lower daily needs may get more flexibility from a moderate-strength capsule instead of taking the full amount each time.

Who is it for
  • Adults wanting a long supply of buffered vitamin C
  • People who prefer one high-potency capsule
  • Users who value clear mineral disclosure
Best for
  • Ongoing high-potency use
  • Immune and antioxidant support
  • Buffered vitamin C routines

Pros

  • Buffered Ester-C form
  • One-capsule full serving
  • Calcium amount is clear
  • Long supply

Cons

  • High amount may be more than needed
  • Limited dose flexibility
  • Bioflavonoid profile is not further detailed

Warnings

  • A large single vitamin C serving can cause loose stools or stomach discomfort in sensitive users even when the form is buffered.

Nutrient quality

89 Highest impact

Ester-C provides a buffered and generally well-tolerated vitamin C form. A high-potency vitamin C amount is paired with a useful bioflavonoid dose.

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Ingredient transparency

84 Highest impact

Every listed active has a specific amount. A complete excipient list is not available in the provided data.

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Customer satisfaction

76 High impact

The average rating is very strong. The large rating volume provides a reliable satisfaction signal.

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Value for money

92 Highest impact

The serving value is competitive for a buffered capsule. The focused formula avoids unnecessary extras.

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Report analysis

Goals

General Health
General Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA+ Formula Quality
Vitamin C · 1000 mg

Buffered vitamin C provides meaningful antioxidant, immune, and collagen support in a stomach-friendly form. Its contribution is useful but narrower than a complete foundational nutrient formula.

The 1,000 mg amount is well targeted, and the calcium contribution is clearly separated on the label. Citrus bioflavonoids complement the antioxidant theme without turning the formula into an unfocused blend.

Study evidence
Vitamin C Supportive 56 studies
Skin Health
Skin Health
Impact
Highest effect
A- Goal FitA+ Strength of SupportC+ CoverageA Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports collagen synthesis and antioxidant protection in skin. Human evidence strongly supports its essential cofactor role, although added benefit depends partly on baseline intake.

The fully disclosed amount is substantial, and buffered Ester-C may be easier on the stomach than plain ascorbic acid. Citrus bioflavonoids add a compatible antioxidant role without diluting the focused formula.

Study evidence
Vitamin C Supportive 53 studies
Immunity
Immunity
Impact
Highest effect
A Goal FitA- Strength of SupportC CoverageB+ Formula Quality
Vitamin C · 1000 mg

Vitamin C supports foundational antioxidant defenses, collagen formation, and normal immune function. The formula supports antioxidant, collagen, and immune pathways but does not fill a broad range of nutrient gaps.

The label presents a substantial 1,000 mg vitamin C serving suited to focused antioxidant support. Ascorbic acid is clearly identified, but the botanical additions do not establish enhanced absorption or buffering.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B- Goal FitA Strength of SupportC CoverageA Formula Quality
Vitamin C · 1000 mg

The full-gram Ester-C dose provides substantial antioxidant support in a buffered form that may suit sensitive stomachs. Citrus bioflavonoids add complementary antioxidant activity.

The formula supports oxidative-stress control more than direct inflammatory-enzyme pathways. Clear disclosure and a lean active list make it a strong supporting formula within that narrower role.

Study evidence
Vitamin C Supportive 50 studies
Vision Support
Vision Support
Impact
High effect
C+ Goal FitA Strength of SupportD+ CoverageB+ Formula Quality
Vitamin C · 1000 mg

Vitamin C supports ocular antioxidant defenses, but the formula lacks the carotenoids and minerals found in broader vision combinations. Vitamin C has an established role in studied antioxidant combinations, while evidence for vitamin C alone preserving vision is limited.

The 1,000 mg amount is substantial and comfortably supplies the antioxidant nutrient. Vitamin C and citrus bioflavonoids form a compatible antioxidant combination.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ester-C)
 1000 mg
Calcium (Ester-C Calcium Ascorbate)
 108 mg
Citrus Bioflavonoids Complex
200 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
Vitamin C (Ester-C) · 1000 mg OverallScore96
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

Ester-C provides a buffered calcium ascorbate form that may suit people who find straight ascorbic acid harsh. The 1,000 mg vitamin C dose is well targeted, with the calcium contribution clearly disclosed. Its larger package keeps the premium form highly cost-efficient per gram.

View ingredientView products
Loading alternative details
87 Performance

Ester-C with Citrus Bioflavonoids

American Health
<p>A full Ester-C amount and substantial citrus bioflavonoid complex preserve the original’s key buffered profile. The supplied quality and goal evidence is slightly more balanced, although the individual flavonoids are not broken out.</p>
86 Performance

C

Swanson
<p>A full amount of calcium ascorbate plus a clearly stated citrus bioflavonoid amount creates a focused buffered formula. The more concise active profile is easier to interpret than the original, though it supplies less total bioflavonoid material.</p>
89 Performance

C-500 Calcium Ascorbate-C

NOW
<p>A clearly stated calcium ascorbate amount and a small citrus bioflavonoid addition make this a focused buffered option. The supplied quality evidence is stronger, but the vitamin C and flavonoid amounts are lower than in the original.</p>
84 Budget

Ester-C 500 mg With Citrus Bioflavoinds

American Health
<p>The same buffered vitamin C amount and broad citrus bioflavonoid profile are provided at a lower serving cost. Ingredient fit is nearly identical to the original, making the smaller package a more economical way to obtain the same core formula.</p>
89 Budget

Pure Buffered Calcium Ascorbate

NOW
<p>Buffered calcium ascorbate supplies a substantial vitamin C amount at a lower serving cost. Citrus bioflavonoids are omitted, but the buffered form preserves the original formula’s main stomach-comfort advantage while reducing cost.</p>
85 Budget

Gold C Vitamin C 1000 mg

California Gold Nutrition
<p>A focused ascorbic acid formula delivers a full vitamin C amount at a lower serving cost. The trade-off is the loss of the buffered form and citrus bioflavonoids found in the original.</p>
84 Value

Ester-C 24 Hour Immune Support 1000 mg

NatureSmart
<p>A full Ester-C amount and defined citrus bioflavonoid complex retain close ingredient alignment while offering favorable value. The flavonoid amount is modest compared with the original, but the buffered vitamin C dose remains intact.</p>
86 Value

Buffered Vitamin C + Citrus Bioflavonoids

Jarrow Formulas
<p>Buffered calcium ascorbate and a substantial bioflavonoid amount provide a useful balance of ingredient fit and value. The vitamin C amount is lower than in the original, while the flavonoid coverage remains meaningful.</p>
87 Value

Pure Buffered Magnesium Ascorbate

NOW
<p>Buffered magnesium ascorbate supplies a substantial vitamin C amount with favorable value and adds magnesium from the same compound. It omits citrus bioflavonoids, but keeps a buffered mineral ascorbate form while lowering formula complexity.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  2. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  3. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  4. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  5. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  6. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  7. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  8. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  9. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  10. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  11. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  12. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  13. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  14. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  15. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  16. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  17. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  18. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  19. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  20. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  21. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  22. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  23. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  24. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  25. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C