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Buffered Vitamin C 1000 mg

4.8
★ ★ ★ ★ ★
(693 ratings)
Vitamin C 1000 mg
Flavonoid (mixture) 150 mg
Product Image
Score70
A diverse vitamin C blend is convenient and well supported by bioflavonoids, but unclear form proportions and high cost reduce confidence.
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Capsule
Quantity:90 Capsule(s) • (90 servings)
Goals:
Immunity
General Health
Skin Health
Anti-Inflammatory Support
Vision Support

Score 70

A diverse vitamin C blend is convenient and well supported by bioflavonoids, but unclear form proportions and high cost reduce confidence.
How scoring works
$45.00($0.50 per serving)
iHerb
$ 45.00
Pure Formulas
$ 45.00
iHerb
$ 45.00
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Analysis

The blend includes ascorbic acid, calcium ascorbate, sodium ascorbate, and fat-soluble ascorbyl palmitate. That form diversity may appeal to users who want more than a basic single-source vitamin C product.

The supplied label data repeat the full vitamin C amount across the forms without clarifying how much each contributes. As a result, buyers cannot determine how fully buffered the serving is or how meaningful the ascorbyl palmitate portion may be.

Citrus bioflavonoids add a useful companion ingredient, while calcium and sodium contributions are separately stated. The one-capsule serving is convenient, but the high ongoing cost weakens value compared with simpler buffered options.

Who is it for
  • Adults seeking several vitamin C forms
  • Users wanting a one-capsule high-potency serving
  • People interested in mineral ascorbates and ascorbyl palmitate
Best for
  • Broad-form vitamin C supplementation
  • Immune and antioxidant support
  • One-capsule convenience

Pros

  • Four vitamin C forms
  • Includes mineral-buffered ascorbates
  • Citrus bioflavonoids are stated
  • Calcium and sodium contributions are disclosed

Cons

  • Contribution of each vitamin C form is unclear
  • Contains some unbuffered ascorbic acid
  • Relatively weak value
  • Ascorbyl palmitate amount cannot be isolated

Warnings

  • People restricting sodium should account for the stated sodium contribution from sodium ascorbate.
  • Sensitive users may still experience digestive discomfort because unbuffered ascorbic acid remains part of the blend.

Nutrient quality

76 High impact

Calcium and sodium ascorbates add buffering, while ascorbyl palmitate adds a lipid-soluble form. Repeated full amounts across four vitamin C forms make the true combined dose unclear.

.

Ingredient transparency

69 High impact

Amounts are shown, but the repeated vitamin C entries are ambiguous. A complete excipient list is not available in the provided data.

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Customer satisfaction

75 High impact

The average rating is very strong. The large rating volume provides a reliable satisfaction signal.

.

Value for money

62 Moderate impact

Serving value is only moderate for the category. The formula avoids many extras, though multiple forms may add complexity without clear benefit.

.
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Goals

Immunity
Immunity
Impact
Highest effect
A+ Goal FitA Strength of SupportC+ CoverageB Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports immune-cell activity, barrier function, and antioxidant defense. Human evidence supports vitamin C for maintaining immune function and modestly shortening some respiratory illnesses.

The disclosed vitamin C amount meets the preferred immune-support threshold. Mineral ascorbates and ascorbyl palmitate add form diversity, although each form's contribution is unclear.

Study evidence
Vitamin C Supportive 53 studies
General Health
General Health
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA Formula Quality
Vitamin C · 1000 mg

Vitamin C provides direct antioxidant, immune, and collagen support at a substantial daily amount. Several ascorbate forms and citrus bioflavonoids broaden the delivery approach.

The formula remains focused on one nutrient pathway rather than comprehensive daily coverage. People with sensitive digestion may still notice discomfort because unbuffered ascorbic acid remains in the blend.

Study evidence
Vitamin C Supportive 56 studies
Skin Health
Skin Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC+ CoverageA Formula Quality
Vitamin C · 1000 mg

A buffered vitamin C blend provides strong collagen-synthesis and antioxidant support. Citrus bioflavonoids add a complementary antioxidant pathway but do not address skin hydration or barrier lipids.

Several vitamin C forms are disclosed clearly, including fat-soluble ascorbyl palmitate. The focused formula offers good depth without an excessive ingredient list.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitA- Strength of SupportC- CoverageA- Formula Quality
Vitamin C · 1000 mg

The 1000 mg vitamin C serving provides substantial antioxidant support that may limit oxidative stress linked with inflammatory signaling. Mineral ascorbates, ascorbic acid, and ascorbyl palmitate broaden the delivery profile, while citrus bioflavonoids add complementary antioxidant activity.

Vitamin C is an indirect anti-inflammatory strategy and does not strongly target pathways such as NF-kB or 5-LOX. The label also does not explain how much each vitamin C form contributes to the stated total.

Study evidence
Vitamin C Supportive 50 studies
Vision Support
Vision Support
Impact
High effect
D+ Goal FitA- Strength of SupportD CoverageB+ Formula Quality
Vitamin C · 1000 mg

Vitamin C contributes retinal antioxidant protection but cannot cover macular pigment or structural needs alone. Vitamin C appears in established ocular nutrient combinations, though standalone evidence is limited for broad vision outcomes.

One gram of vitamin C supplies a meaningful antioxidant amount rather than a token inclusion. Mineral ascorbates and ascorbyl palmitate broaden delivery, but each form’s contribution is not separated.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid, Calcium Ascorbate, Sodium Ascorbate, Ascorbyl Palmitate)
 1000 mg
Calcium (Calcium Ascorbate)
 24 mg
Sodium (Sodium Ascorbate)
 25 mg
Citrus Bioflavonoids
150 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Vitamin C (Ascorbic Acid, Calcium Ascorbate, Sodium Ascorbate, Ascorbyl Palmitate) · 1000 mg OverallScore71
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyF Value

A blend of ascorbic acid, mineral ascorbates, and fat-soluble ascorbyl palmitate offers broader form diversity than basic vitamin C. Because unbuffered ascorbic acid remains part of the blend, digestive comfort is less certain than with a fully mineral-buffered formula. The supplied label data do not clarify each forms contribution, and the cost per gram is relatively high.

View ingredientView products
Loading alternative details
89 Performance

C-500 Calcium Ascorbate-C

NOW
<p>The ingredient profile makes it a stronger quality-focused alternative for the same vitamin C goals. Buffered calcium ascorbate delivers a practical vitamin C amount with clear mineral disclosure and exceptional relative value. The small bioflavonoid addition is unlikely to contribute much but does not undermine the strong core formula.</p>
86 Performance

C

Swanson
<p>The ingredient profile makes it a stronger quality-focused alternative for the same vitamin C goals. Fully buffered calcium ascorbate provides a meaningful vitamin C serving with good stomach-comfort potential. The focused formula keeps the active nutrient clear and avoids decorative additions.</p>
87 Performance

Ester-C with Citrus Bioflavonoids

American Health
<p>The ingredient profile makes it a stronger quality-focused alternative for the same vitamin C goals. A buffered vitamin C form and a substantial citrus bioflavonoid amount create a simple, well-dosed antioxidant formula. Strong satisfaction signals and a long supply support value, though excipients and intake directions are not shown.</p>
89 Budget

Pure Buffered Calcium Ascorbate

NOW
<p>The lower serving cost makes it a more economical alternative while retaining the same vitamin C focus. the buffered mineral ascorbate form supplies a meaningful vitamin C amount with a digestive-comfort advantage over plain ascorbic acid. Clear active dosing and favorable serving value are strengths, though complete use directions and inactive ingredients are not supplied.</p>
87 Budget

100% Pure Vitamin C Powder

Swanson Premium Brand
<p>The lower serving cost makes it a more economical alternative while retaining the same vitamin C focus. The pure powder supplies a flexible, meaningful vitamin C serving with exceptional economy and no active padding. Plain ascorbic acid remains acidic, so sensitive users may prefer a buffered form.</p>
87 Budget

C 500 mg

Mason Natural
<p>The lower serving cost makes it a more economical alternative while retaining the same vitamin C focus. A simple moderate-dose tablet provides useful vitamin C at excellent relative value and with extensive aggregate feedback. Generic ascorbic acid and missing inactive-ingredient details are the main limitations.</p>
87 Value

Pure Buffered Magnesium Ascorbate

NOW
<p>The formula offers a more favorable balance of vitamin C quality and serving value than the original. Magnesium ascorbate provides a substantial fully buffered vitamin C serving with excellent relative value and clear mineral disclosure. Feedback volume is limited, and detailed use directions or non-active ingredients are not supplied.</p>
83 Value

C 500 mg

21st Century
<p>The formula offers a more favorable balance of vitamin C quality and serving value than the original. A large supply of straightforward vitamin C provides meaningful daily support with excellent value. Basic ascorbic acid and incomplete inactive-ingredient details keep the formula from feeling premium.</p>
84 Value

Ester-C 500 mg With Citrus Bioflavoinds

American Health
<p>The formula offers a more favorable balance of vitamin C quality and serving value than the original. Buffered Ester-C provides a substantial vitamin C serving with good stomach-comfort potential. Citrus bioflavonoids add compatible plant compounds without distracting from the core nutrient.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  2. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  3. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  4. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  5. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  6. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  7. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  8. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  9. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  10. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  11. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  12. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  13. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  14. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  15. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  16. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  17. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  18. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  19. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  20. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  21. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  22. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  23. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  24. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  25. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C