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Ascorbyl Palmitate 500 mg

4.7
★ ★ ★ ★ ★
(253 ratings)
Vitamin C 203 mg
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Score77
A specialized ascorbyl palmitate tablet with clear disclosure, but only a modest amount of actual vitamin C. Its form matters more than its dose efficiency.
How scoring works
Tablet
Quantity:90 Tablet(s) • (90 servings)
Goals:
General Health
Immunity
Skin Health
Anti-Inflammatory Support

Score 77

A specialized ascorbyl palmitate tablet with clear disclosure, but only a modest amount of actual vitamin C. Its form matters more than its dose efficiency.
How scoring works
$13.40($0.14 per serving)
iHerb
$ 13.40
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Analysis

Ascorbyl palmitate provides a lipid-soluble antioxidant form that differs from standard water-soluble ascorbic acid. The label identifies 203 mg of vitamin C from 500 mg of the source compound, helping prevent confusion about the active amount.

The actual vitamin C amount is useful but lower than many dedicated vitamin C products. Calcium is present as dibasic calcium phosphate, but it does not materially broaden the product's main purpose.

The specialized ester may appeal to someone deliberately seeking this form. Buyers mainly interested in a substantial daily vitamin C amount can find more direct and efficient options.

Who is it for
  • Adults specifically seeking ascorbyl palmitate
  • Users wanting a lipid-soluble vitamin C ester
  • People comfortable with a modest vitamin C amount
Best for
  • Specialized antioxidant support
  • Adding a distinct vitamin C form
  • Low-complexity supplementation

Pros

  • Distinct lipid-soluble ester form
  • Actual vitamin C amount is clearly separated
  • Simple ingredient focus

Cons

  • Only 203 mg of actual vitamin C
  • Source amount can be mistaken for active vitamin C
  • Calcium adds little to the main purpose

Nutrient quality

80 Highest impact

Ascorbyl palmitate is a specialized lipid-soluble vitamin C form, although its practical absorption advantage is uncertain. The actual vitamin C contribution is modest for a dedicated vitamin C supplement.

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Ingredient transparency

84 Highest impact

The source-compound amount and actual vitamin C contribution are both disclosed. A complete inactive ingredient list was not supplied.

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Customer satisfaction

64 Moderate impact

The available aggregate rating is strong for this category. No firsthand outcome details were supplied, so alignment with the intended use is uncertain.

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Value for money

75 High impact

The specialized ester form partly supports the cost, but the actual vitamin C amount is modest. Comparable vitamin C products often provide more active vitamin C for the serving cost.

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Goals

General Health
Impact
High effect
B+ Goal FitC Strength of SupportD+ CoverageB+ Formula Quality
Vitamin C · 500 mg

Ascorbyl palmitate provides a distinct lipid-soluble vitamin C form with clearly identified active content. Vitamin C remains relevant to antioxidant protection and collagen formation.

The actual vitamin C contribution is modest compared with stronger daily vitamin C products. The focused formula is easy to understand but covers only one pillar of general health.

Study evidence
Vitamin C Supportive 56 studies
Immunity
Impact
High effect
B- Goal FitC Strength of SupportF CoverageA+ Formula Quality
Vitamin C · 500 mg

Vitamin C has direct immune relevance, but the actual vitamin C amount falls below the main dose target. The lipid-soluble ester is distinctive yet still supports only one main immune pathway.

The label clearly separates the source-compound amount from the actual vitamin C contribution. Ascorbyl palmitate offers a specialized form, although the lower active amount limits practical immune depth.

Study evidence
Vitamin C Supportive 53 studies
Skin Health
Impact
High effect
B- Goal FitC Strength of SupportD CoverageA- Formula Quality
Vitamin C · 500 mg

Vitamin C supports collagen synthesis and antioxidant defense, giving the formula a clear but narrow skin-health role. Lipid-soluble ascorbyl palmitate provides a distinct antioxidant form, but the actual vitamin C contribution is modest.

The source-compound amount is much larger than the usable vitamin C amount, which can make the label easy to misread. A single vitamin C product does not directly supply collagen peptides, barrier lipids, or dedicated hydration actives.

Study evidence
Vitamin C Supportive 53 studies
Impact
Moderate effect
D Goal FitC- Strength of SupportF CoverageA Formula Quality
Vitamin C · 500 mg

Ascorbyl palmitate supplies a lipid-soluble vitamin C form with antioxidant relevance. Actual vitamin C delivery is modest and does not directly target major inflammatory enzymes.

The formula is transparent and streamlined, but calcium adds no meaningful anti-inflammatory breadth. Its main value is as a specialized vitamin C source rather than comprehensive inflammation support.

Study evidence
Vitamin C Supportive 50 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbyl Palmitate)
203 mg
Calcium (Dibasic Calcium Phosphate)
102 mg
Ascorbyl Palmitate (Vitamin C Ester)
500 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
B- Active Ingredient Quality & BioavailabilityC- Dose, Safety & Label TransparencyD+ Value

Lipid-soluble ascorbyl palmitate offers a distinct form and clearly identifies the amount of actual vitamin C it supplies. The active vitamin C dose is below the preferred range despite the larger source-compound amount on the label. Value is only average, so the ester format matters more than dose efficiency for the intended buyer.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis.
    Bjelakovic G; Nikolova D; Gluud LL; Simonetti RG; Gluud C · JAMA · 2007
    Meta-analysis232,606 participants68 studies pooledGeneral Health forVitamin C
  2. Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses.
    Xu K; Peng R; Zou Y; Jiang X; Sun Q; Song C · International journal of food sciences and nutrition · 2022
    Meta-analysis76 studies pooledGeneral Health forVitamin C
  3. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  4. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  5. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  6. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  7. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  8. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  9. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  10. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  11. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  12. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  13. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  14. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  15. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  16. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  17. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  18. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  19. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  20. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  21. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  22. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C