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Niacin (Vitamin B3) 500 mg

Solgar
4.6
★ ★ ★ ★ ★
(889 ratings)
Niacin 500 mg
Product Image
Score80
A clearly labeled, pharmacologically active nicotinic acid capsule for supervised lipid use, with significant flushing and monitoring trade-offs.
How scoring works
Quantity:100 Capsule(s) • (100 servings)
Goals:
Cardiovascular Support
Heart Health

Score 80

A clearly labeled, pharmacologically active nicotinic acid capsule for supervised lipid use, with significant flushing and monitoring trade-offs.
How scoring works
$12.29($0.12 per serving)
Daily Vita
$ 13.52
Pure Formulas
$ 12.29
iHerb
$ 12.29
Vitacost
$ 12.45
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Analysis

Nicotinic acid is the form of niacin that can meaningfully alter lipid markers. The chemical identity and large amount are clearly disclosed, removing the main ambiguity seen in many niacin products.

The capsule has no stated timed-release feature and the supplied details do not include clear flush guidance. It also covers one lipid pathway rather than broad cardiovascular support.

It fits clinician-guided lipid use more than general wellness or skin support. The dose is high enough that tolerance and laboratory monitoring matter.

Who is it for
  • Adults using nicotinic acid under clinical guidance
  • People with a form-specific lipid-management plan
  • Users prepared for predictable flushing
Best for
  • Clinician-guided lipid-marker support
  • Form-specific nicotinic acid use
  • Single-ingredient therapy support

Pros

  • Nicotinic acid is explicitly identified
  • Pharmacologically meaningful amount
  • Focused single-ingredient formula

Cons

  • No timed-release design is stated
  • Not broad cardiovascular support
  • Poor fit for skin-focused use

Warnings

  • The serving can cause pronounced warmth, redness, itching, or tingling
  • Regular use can affect liver enzymes, glucose control, and uric acid
  • Do not substitute it for prescribed cardiovascular treatment
  • Lipid-directed use warrants clinical supervision

Nutrient quality

76 High impact

Nicotinic acid is a clear and well-established vitamin B3 form supplied at a pharmacologically meaningful amount. Flushing and other dose-related effects make the formula aggressive for general supplementation.

Ingredient transparency

88 Highest impact

The active amount and serving size are clear, with no proprietary blend hiding the formula. Non-active ingredients and complete usage directions are not supplied.

Customer satisfaction

68 High impact

The average rating is strong, with a substantial review count supporting the signal. No detailed reviews are supplied to assess repeated complaints or intended-use experiences.

Value for money

85 Highest impact

Clear form disclosure and a long supply support reasonable value. The aggressive amount reduces suitability and may add monitoring needs.

Report analysis

Goals

Cardiovascular Support
Cardiovascular Support
Impact
Highest effect
A Goal FitA- Strength of SupportC+ CoverageA+ Formula Quality
Niacin · 500 mg

Nicotinic acid is the niacin form with established effects on blood lipids, and the amount is clinically meaningful. Its use for lipid management needs more care than a routine low-dose vitamin supplement.

The single active is fully disclosed, but no timed-release design or tolerance guidance is provided. This amount can cause pronounced warmth, redness, itching, or tingling from niacin flushing.

Study evidence
Niacin Supportive 136 studies
Heart Health
Heart Health
Impact
Highest effect
B+ Goal FitA Strength of SupportD+ CoverageA+ Formula Quality

Nicotinic acid can modify lipid markers, making it a situational cardiovascular option rather than general daily heart support. Evidence has not shown consistent added cardiovascular-event benefit when it is layered onto modern statin therapy.

The 500 mg amount is pharmacologically meaningful and uses the active flushing form. It can cause marked warmth, redness, tingling, liver strain, or worsened glucose control, so lipid-directed use should be medically supervised.

Study evidence
Niacin Supportive 105 studies

Ingredients

IngredientAmount per serving
Niacin (Nicotinic Acid)
 500 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Women Vegetarian
Report overview
Niacin (Nicotinic Acid) · 500 mg OverallScore80
A Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value

Nicotinic acid at 500 mg is well aligned with uses that depend on this specific niacin form. The capsule provides a research-relevant amount, but the supplied label details do not show a timed-release design. A missing flush warning is important because this dose can cause temporary redness, warmth, or tingling.

View ingredientView products
Loading alternative details
82 Performance

Sustained-Release Niacin with niaXtend 500 mg

Doctor's Best
<p>Sustained-release nicotinic acid provides a clearly identified cardiovascular-focused amount with controlled delivery. Compared with the original, it provides clearer form disclosure or a more purposeful match for cardiovascular-focused niacin use; however, high-dose niacin can still affect the liver and requires explicit safety guidance.</p>
79 Performance

Niacin-Time 500 mg

Carlson
<p>Timed-release nicotinic acid provides a transparent cardiovascular-focused dose in a long-supply format. Compared with the original, it provides clearer form disclosure or a more purposeful match for cardiovascular-focused niacin use; however, controlled delivery does not remove flushing or liver-related concerns from high-dose niacin.</p>
82 Performance

No Flush Niacin (Inositol Hexanicotinate) 800 mg

Life Extension
<p>Clearly named inositol hexanicotinate provides substantial flush-free niacin exposure with economical serving value. Compared with the original, it provides clearer form disclosure or a more purposeful match for cardiovascular-focused niacin use; however, its cardiovascular effects may be less direct and reliable than those of nicotinic acid.</p>
86 Budget

Niacinamide B-3 100 mg

Source Naturals
<p>A clearly identified moderate niacinamide tablet offers simple non-flushing vitamin B3 support with excellent serving economics. Serving cost is lower than the original, but it does not provide nicotinic acid’s lipid-focused effects and complete excipient details are missing.</p>
82 Budget

Niacin 100 mg

Nature's Way
<p>Clearly identified nicotinic acid supplies a modest, inexpensive vitamin B3 serving with direct form transparency. Serving cost is lower than the original, but immediate release can still cause temporary flushing and the dose is not intended for intensive cardiovascular use.</p>
82 Budget

Niacin 100 mg

Bluebonnet
<p>Clearly identified nicotinic acid provides a meaningful low-dose option in a simple long-supply capsule. Serving cost is lower than the original, but noticeable flushing remains possible and people sensitive to liver, glucose, or blood-pressure effects should choose carefully.</p>
80 Value

Niacin 50 mg

Carlson
<p>A clearly named low-dose nicotinic acid tablet provides economical and easy-to-assess vitamin B3 support. Its lower serving cost and clearer active design support practical value compared with the original, although the amount is too low for focused cardiovascular use and can still cause flushing.</p>
85 Value

Niacin 100 mg

Source Naturals
<p>A moderate niacinamide tablet provides clearly identified vitamin B3 without typical nicotinic-acid flushing. Its lower serving cost and clearer active design support practical value compared with the original, although the form is intended for nutritional or skin support rather than lipid-focused effects.</p>
80 Value

No-Flush Niacin (Inositol Hexanicotinate) 500 mg

Solgar
<p>Clearly identified inositol hexanicotinate supports a comfort-focused no-flush approach with good serving value. Its quality-adjusted serving economics and clearer active design support practical value compared with the original, although the form is less direct than nicotinic acid for cardiovascular purposes.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease.
    Duggal JK; Singh M; Attri N; Singh PP; Ahmed N; Pahwa S; Molnar J; Singh S; Khosla S; Arora R · Journal of cardiovascular pharmacology and therapeutics · 2010
    Meta-analysis5,137 participants7 studies pooledHeart Health forNiacin
  2. Role of Niacin in Current Clinical Practice: A Systematic Review.
    Garg A; Sharma A; Krishnamoorthy P; Garg J; Virmani D; Sharma T; Stefanini G; Kostis JB; Mukherjee D; Sikorskaya E · The American journal of medicine · 2017
    Meta-analysis35,206 participants13 studies pooledHeart Health forNiacin
  3. Relationship of lipoproteins to cardiovascular events: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes).
    Guyton JR; Slee AE; Anderson T; Fleg JL; Goldberg RB; Kashyap ML; Marcovina SM; Nash SD; O'Brien KD; Weintraub WS; Xu P; Zhao XQ; Boden WE · Journal of the American College of Cardiology · 2013
    Randomized trial3,414 participantsHeart Health Cardiovascular Support forNiacin
  4. Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis.
    D'Andrea E; Hey SP; Ramirez CL; Kesselheim AS · JAMA network open · 2020
    Meta-analysis35,760 participants17 studies pooledHeart Health forNiacin
  5. Exploring the Cardiovascular Impacts of Oral Nicotinamide: A Comprehensive Narrative Review.
    Shoukfeh R; Tisack AM; Lim HW; Mohammad TF · Journal of drugs in dermatology : JDD · 2025
    Narrative reviewHeart Health forNiacin
  6. The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration.
    Villines TC; Stanek EJ; Devine PJ; Turco M; Miller M; Weissman NJ; Griffen L; Taylor AJ · Journal of the American College of Cardiology · 2010
    Randomized trial315 participantsHeart Health forNiacin
  7. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  8. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  9. Niacin improves lipid profile but not endothelial function in patients with coronary artery disease on high dose statin therapy.
    Philpott AC; Hubacek J; Sun YC; Hillard D; Anderson TJ · Atherosclerosis · 2013
    Randomized trial66 participantsCardiovascular Support forNiacin
  10. Supplemental Vitamins and Minerals for Cardiovascular Disease Prevention and Treatment: JACC Focus Seminar.
    Jenkins DJA; Spence JD; Giovannucci EL; Kim YI; Josse RG; Vieth R; Sahye-Pudaruth S; Paquette M; Patel D; Blanco Mejia S; Viguiliouk E; Nishi SK; Kavanagh M; Tsirakis T; Kendall CWC; Pichika SC; Sievenpiper JL · Journal of the American College of Cardiology · 2021
    Meta-analysisCardiovascular Support forNiacin
  11. Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: A randomized trial. Arterial Disease Multiple Intervention Trial.
    Elam MB; Hunninghake DB; Davis KB; Garg R; Johnson C; Egan D; Kostis JB; Sheps DS; Brinton EA · JAMA · 2000
    Randomized trial468 participantsCardiovascular Support forNiacin
  12. Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
    Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
    Meta-analysis145,314 participants147 studies pooledCardiovascular Support forNiacin
  13. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
    Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
    Randomized trial173 participantsCardiovascular Support forNiacin
  14. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
    Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
    Randomized trial223 participantsCardiovascular Support forNiacin
  15. Differential effect of two nicotinic acid preparations on low-density lipoprotein subclass distribution in patients classified as low-density lipoprotein pattern A, B, or I.
    Superko HR; McGovern ME; Raul E; Garrett B · The American journal of cardiology · 2004
    Randomized trial180 participantsHeart Health forNiacin
  16. The effects of extended-release niacin on carotid intimal media thickness, endothelial function and inflammatory markers in patients with the metabolic syndrome.
    Thoenes M; Oguchi A; Nagamia S; Vaccari CS; Hammoud R; Umpierrez GE; Khan BV · International journal of clinical practice · 2008
    Randomized trial50 participantsHeart Health forNiacin
  17. Effect of niacin on endothelial function: a systematic review and meta-analysis of randomized controlled trials.
    Sahebkar A · Vascular medicine (London, England) · 2014
    Meta-analysis441 participants7 studies pooledHeart Health forNiacin