Niacin 100 mg
Nature's Way
Niacin 100 mg
4.6
★ ★ ★ ★ ★
(4293 ratings)
Niacin 100 mg
Score 65.0
A basic nicotinic acid supplement at a lower dose, suitable for general B vitamin support but likely insufficient for therapeutic heart health benefits, and will cause the niacin flush.
Quantity: 100 Capsule(s)Servings size: 1 Capsule(s) (100 servings)
Selected goals:
Other goals:
Heart Health
Skin Health
Energy
Metabolism Boost
leaderboard Score 65.0
A basic nicotinic acid supplement at a lower dose, suitable for general B vitamin support but likely insufficient for therapeutic heart health benefits, and will cause the niacin flush.
insights Analysis
Nature's Way Niacin 100 mg provides nicotinic acid, the form of niacin historically used for its cardiovascular benefits, though at 100mg it's a relatively low dose for significant cholesterol modulation. This dose is more commonly used for general B vitamin supplementation and energy production. A key consideration with nicotinic acid is the "niacin flush," a temporary redness, itching, or tingling sensation that can occur, which many users find uncomfortable.
- Very low price per serving
- Simple formulation with pure nicotinic acid
- Low dose for significant heart health benefits
- Causes the 'niacin flush' which can be uncomfortable for many users
- May cause 'niacin flush' (redness, itching, tingling). Start with a low dose and increase gradually if tolerated.
$3.65($0.03 per serving)
 Pure Formulas | $ 3.65 | |
 iHerb | $ 4.08 | |
 Vitacost | $ 4.29 |
bolt Effectiveness for goals
Niacin is known as one of the most effective agents for increasing high-density lipoprotein (HDL) cholesterol levels. It can significantly raise HDL, which is often considered beneficial for cardiovascular health. However, studies have shown that this increase in HDL does not always translate to a reduction in cardiovascular events.
While Niacin can contribute to lowering LDL cholesterol, its primary effect on lipids is typically a more significant reduction in triglycerides and an increase in HDL cholesterol. For LDL reduction, it is generally considered less potent than statins and often used in conjunction with other lipid-lowering therapies if prescribed.
Yes, Niacin is highly effective at reducing elevated triglyceride levels. It achieves this by decreasing the liver's production of very low-density lipoprotein (VLDL), which is a precursor to triglycerides and LDL cholesterol. This makes it a common consideration for individuals with hypertriglyceridemia.
Niacin, also known as vitamin B3, is primarily recognized for its role in preventing and treating pellagra, a deficiency disease. In supplement form, it has been extensively studied for its effects on cholesterol and triglyceride levels. Its physiological functions include energy metabolism and DNA repair.
Niacin can be used in combination with statins to further improve lipid profiles, particularly to increase HDL and lower triglycerides. However, some studies have shown that adding Niacin to statin therapy does not consistently provide additional cardiovascular benefits and may increase the risk of side effects such as myopathy (muscle pain) when taken with certain statins. Medical supervision is essential for this combination.
schedule Dosage, timing & forms
Nicotinic acid is the form most commonly associated with the 'niacin flush' and is often used at higher doses for specific health support under medical supervision. Niacinamide (nicotinamide) generally does not cause flushing and is often preferred for general vitamin B3 supplementation, though it has different metabolic effects compared to nicotinic acid. Their applications can differ significantly.
'Flush-free' niacin, often inositol hexanicotinate, is a form where niacin is chemically bound to inositol, a sugar-like compound. This bond leads to a slow, gradual release of niacin in the body, significantly reducing or eliminating the rapid vasodilation that causes the common flushing sensation. It's often chosen by individuals sensitive to the flush.
To minimize the niacin flush from immediate-release nicotinic acid, individuals can start with a very low dose and gradually increase it over time. Taking it with a non-fatty meal, avoiding hot beverages or alcohol around the time of dosing, and potentially taking aspirin 30 minutes beforehand (if medically appropriate and advised) can also help. Slow and steady increases in dosage are key.
Immediate-release niacin (nicotinic acid) is absorbed quickly, leading to a rapid peak effect and often a pronounced, but temporary, flush. Extended-release forms are designed to release niacin slowly over several hours, which can help reduce the intensity and duration of the flush and may allow for less frequent dosing. The slower release aims to improve tolerance.
Niacin is available in several forms, including nicotinic acid (immediate-release and extended-release), niacinamide (nicotinamide), and inositol hexanicotinate (often marketed as 'no-flush' niacin). Each form has distinct properties and effects within the body. The choice of form can influence how it is absorbed and its potential side effects.
health_and_safety Safety & interactions
The niacin flush is a common side effect characterized by redness, itching, warmth, and tingling, primarily on the face, neck, and chest. It is caused by the release of prostaglandins, which dilate blood vessels. Taking niacin with food, starting with a low dose and gradually increasing it, or taking a low-dose aspirin before niacin may help reduce the flush.
High doses of niacin, particularly sustained-release forms, have been associated with elevated liver enzymes and, in rare cases, liver toxicity. Regular monitoring of liver function by a healthcare professional is often recommended when taking high-dose niacin. Individuals with pre-existing liver conditions should avoid niacin unless specifically advised by a doctor.
Yes, niacin can interact with several medications. It may enhance the effects of blood pressure-lowering drugs, potentially causing hypotension, and can increase the risk of myopathy when taken with statins. Niacin might also interact with blood thinners, antidiabetic medications, and gout medications. Consulting a healthcare provider about all current medications before starting niacin is important.
Individuals with active liver disease, severe hypotension, active peptic ulcer disease, or active bleeding should generally avoid niacin supplements. Those with a history of gout, diabetes, or gallbladder disease should also use niacin with caution and under medical supervision. Consultation with a healthcare provider is essential to determine suitability.
High doses of niacin, particularly nicotinic acid, can sometimes increase blood glucose levels. This effect is more pronounced in individuals with diabetes or prediabetes. People managing their blood sugar should monitor their levels closely if taking niacin and discuss its use with a healthcare provider.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Niacin | 100 mg |
Categories
Niacin 70.0
This product is a straightforward niacin supplement, providing the traditional nicotinic acid form. Its effectiveness is limited by the relatively low dosage for some common uses of niacin.
Goals
Energy 80.0
As a B vitamin, niacin is crucial for metabolic pathways that convert food into energy. 100mg is an effective dose for supporting daily energy metabolism.
Metabolism Boost 80.0
Niacin is a vital coenzyme in many metabolic reactions, including those involved in carbohydrate, fat, and protein metabolism, thus supporting overall metabolic function effectively at this dose.
Skin Health 70.0
Niacin contributes to overall skin health and repair processes. However, niacinamide is generally preferred by dermatologists for direct topical and oral skin benefits due to its anti-inflammatory properties and lack of flush.
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97 Value
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4.7
★★★★★
(8865 ratings)
Offers a significantly higher 500mg dose of flush-free Niacinamide from a premium brand for only twice the price per serving, delivering exceptional value for a high-quality product that avoids the flush.
93 Value
Niacin 500 mg
NOW
4.6
★★★★★
(8550 ratings)
For those seeking a higher dose of standard nicotinic acid, this NOW product provides 500mg for only twice the price per serving, representing a strong value from a trusted brand, assuming the niacin flush is acceptable.
90 Value
Niacin 500 mg
21st Century
4.5
★★★★★
(1747 ratings)
A highly cost-effective option providing a significant 500mg dose of standard Niacin. While a budget brand, it offers great value for those prioritizing high dosage at a very low price per serving.
98 Performance
Niacinamide 500 mg
NOW
4.7
★★★★★
(8865 ratings)
This Niacinamide product from a highly reputable brand offers a flush-free experience at a higher 500mg dose, addressing the primary drawback (niacin flush) of the original nicotinic acid while providing general B3 benefits.
95 Performance
Niacinamide 500 mg
Solaray
4.6
★★★★★
(4628 ratings)
Another excellent flush-free Niacinamide option from a well-regarded brand. It provides a higher 500mg dose, making it suitable for broader B3 support without the typical flush.
90 Performance
No-Flush Niacin 500 mg
Source Naturals
4.7
★★★★★
(745 ratings)
This alternative explicitly offers a 'No-Flush' Niacin (Inositol Hexanicotinate) at a higher 500mg dose, directly mitigating the flush common with the original product's form.