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Puri-T

LifeSeasons
4.6
★ ★ ★ ★ ★
(405 ratings)
Selenium 250 mcg
Resveratrol 25 mg
Milk Thistle 225 mg
Turmeric 25 mg
Product Image
Score67
A coherent liver-support blend with a solid milk thistle and N-acetyl cysteine core, but selenium is high and several extras are token doses.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Detoxification
Immunity
General Health

Score 67

A coherent liver-support blend with a solid milk thistle and N-acetyl cysteine core, but selenium is high and several extras are token doses.
How scoring works
$30.98($1.03 per serving)
iHerb
$ 30.99
Pure Formulas
$ 30.99
Amazon
$ 30.98
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Analysis

Milk thistle, dandelion, N-acetyl cysteine, and artichoke form a sensible liver-oriented core. The label discloses each amount, and the combination covers antioxidant support as well as bile-related digestive pathways.

Selenium is substantial at 250 mcg, while milk thistle and dandelion each provide 225 mg. Turmeric, resveratrol, barberry, and chicory are present at only 25 mg apiece, so they add breadth more than strong standalone effects.

The formula is coherent and easier to assess than a proprietary blend. Its serving cost is moderate-to-high, and the elevated selenium amount requires more attention than the otherwise practical botanical profile.

Who is it for
  • Adults seeking broad liver-oriented botanical support
  • People who want milk thistle paired with N-acetyl cysteine
Best for
  • Multi-pathway liver support
  • Milk thistle and antioxidant coverage

Pros

  • 225 mg milk thistle extract
  • 200 mg N-acetyl cysteine
  • Artichoke and dandelion add coherent support
  • All active amounts are disclosed

Cons

  • Turmeric is only 25 mg
  • Resveratrol is only 25 mg
  • Several minor botanicals are lightly dosed
  • Serving value is only moderate

Warnings

  • The 250 mcg selenium amount can push total intake unnecessarily high when combined with other selenium supplements.
  • Barberry may add to glucose-lowering effects in people using insulin or other diabetes medicines.

Nutrient quality

71 High impact

The central liver-support ingredients are coherent and meaningfully represented. High selenium and several token botanicals reduce balance and depth.

.

Ingredient transparency

75 High impact

All active weights are listed without a hidden blend. Extract standardization, complete directions, and inactive ingredients remain missing.

.

Customer satisfaction

65 High impact

The average customer rating is strong. The rating base is adequate but not especially deep, while specific review experiences were not supplied.

.

Value for money

51 Moderate impact

Serving economics are weak. Formula weaknesses do not justify the asking price well.

.
Report analysis

Goals

Detoxification
Detoxification
Impact
Highest effect
A Goal FitB Strength of SupportA- CoverageB Formula Quality
Selenium · 250 mcgMilk Thistle · 225 mg

Milk thistle, NAC, selenium, artichoke, and dandelion create a strong liver-support core. The combination may support glutathione production, antioxidant enzymes, liver-cell protection, and bile-related clearance.

NAC and turmeric are modest compared with common standalone amounts, and several minor botanicals appear too small to add much depth. The 250 mcg selenium amount is substantial and should be considered alongside selenium from food or other supplements.

Study evidence
Milk Thistle Supportive 46 studies
Selenium Supportive 10 studies
Immunity
Immunity
Impact
High effect
C+ Goal FitB Strength of SupportC+ CoverageB- Formula Quality
Selenium · 250 mcg

Selenium, milk thistle, dandelion, N-acetyl cysteine, and artichoke form a focused antioxidant and liver-support blend. Selenomethionine is a well-absorbed mineral form, and most botanical amounts are disclosed.

The formula is narrower than broad daily nutrition, while curcumin, resveratrol, barberry, and chicory appear only at small amounts. The selenium amount leaves limited room for additional selenium from other supplements, so stacking should be avoided.

Study evidence
Resveratrol Mixed 7 studies
Selenium Mixed 37 studies
General Health
General Health
Impact
High effect
B Goal FitC+ Strength of SupportC CoverageD+ Formula Quality
Selenium · 250 mcg

Selenomethionine supplies a well-absorbed trace mineral that may support antioxidant enzymes, thyroid function, and immune readiness. N-acetyl cysteine and several plant extracts extend the antioxidant theme.

The selenium amount is effective but leaves less room for selenium from food and other supplements. Several botanicals appear in small amounts, so the broad formula may offer less depth than its ingredient count suggests.

Study evidence
Selenium Supportive 70 studies

Ingredients

IngredientAmount per serving
Selenium (Selenomethionine)
 250 mcg
Milk Thistle seed extract (Silymarin)
 225 mg
Dandelion root extract
225 mg
N-Acetyl Cysteine
200 mg
Artichoke leaf extract
150 mg
Turmeric root extract (Curcuminoids)
 25 mg
Resveratrol (Polygonum cuspidatum)
 25 mg
Barberry
25 mg
Chicory
25 mg
Gluten Free Adults 18–50 Dairy Free Vegetarian
Report overview
Selenium (Selenomethionine) · 250 mcg OverallScore63
A- Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyF Value

Organic selenomethionine offers a well-absorbed selenium source, although the label does not identify the active L-isomer. The amount remains effective but leaves less room for selenium from food or other supplements. Its high standardized cost weakens value for selenium alone.

View ingredientView products
Resveratrol (Polygonum cuspidatum) · 25 mg OverallScore23
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The 25 mg knotweed-derived resveratrol dose is too small for focused resveratrol support. A standard capsule provides no special absorption help, and the label does not confirm the active trans form or emodin removal. The high serving cost produces weak value for the disclosed resveratrol amount.

View ingredientView products
Milk Thistle (Silymarin) · 225 mg OverallScore14
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The seed extract is clearly identified, but the label does not state a silymarin percentage or active amount. A standard dry capsule also offers no stated absorption support. The high serving cost is difficult to justify when potency remains unclear, and the added selenium warrants attention for people already using selenium supplements.

View ingredientView products
Loading alternative details
74 Performance

Active Liver

New Nordic
<p>Artichoke, milk thistle, and turmeric provide coherent liver and bile support. A more coherent liver or antioxidant profile strengthens the comparison with the original, though missing active-marker yields still limit potency certainty.</p>
74 Performance

Liver Rescue

HealthForce SuperFoods
<p>A substantial milk thistle extract leads a coherent liver-support blend. A more coherent liver or antioxidant profile strengthens the comparison with the original, though missing active-marker yields still limit potency certainty.</p>
69 Performance

Liver Detox & Blood Refresh

Irwin Naturals
<p>A substantial silymarin amount anchors direct liver and antioxidant support, while vitamin C, selenium, burdock, and dandelion broaden the formula. A more coherent liver or antioxidant profile strengthens the comparison with the original, though missing active-marker yields still limit potency certainty.</p>
81 Budget

Milk Thistle Phytosome 150 mg

Natural Factors HerbalFactors
<p>Phytosome delivery meaningfully improves the milk thistle absorption case. The lower serving cost improves accessibility compared with the original, but narrower liver coverage or lightly dosed supporting ingredients limit interchangeability.</p>
78 Budget

Silymarin Milk Thistle Extract 150 mg

NOW
<p>Milk thistle flavonoids and a substantial turmeric weight suit liver-support use. The lower serving cost improves accessibility compared with the original, but narrower liver coverage or lightly dosed supporting ingredients limit interchangeability.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>Milk thistle anchors a coherent liver-support combination with dandelion, artichoke, turmeric, ginger, and black pepper. The lower serving cost improves accessibility compared with the original, but narrower liver coverage or lightly dosed supporting ingredients limit interchangeability.</p>
76 Value

Silymarin Milk Thistle Extract 150 mg

NOW
<p>Milk thistle and turmeric form a sensible liver-support pairing at substantial labeled weights. Relevant liver-support or antioxidant ingredients at a lower serving cost improve value, while incomplete standardization keeps the comparison qualified.</p>
74 Value

Liv-Gall Cleanse

Natural Factors HerbalFactors
<p>Artichoke, milk thistle, turmeric, and dandelion create a coherent liver-focused blend. Relevant liver-support or antioxidant ingredients at a lower serving cost improve value, while incomplete standardization keeps the comparison qualified.</p>
65 Value

Super Thisilyn

Nature's Way
<p>Milk thistle anchors a broad liver-support blend with artichoke, NAC, methionine, turmeric, and alpha-lipoic acid at favorable value. Relevant liver-support or antioxidant ingredients at a lower serving cost improve value, while incomplete standardization keeps the comparison qualified.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Selenium-Biofortified Strawberries Improve Glucose Homeostasis and Hepatic Function: A 30-Day Randomized Controlled Trial in Healthy Adults.
    Vasto S; Di Rosa L; Ferrantelli V; Fiore AS; Giordano CP; Cannizzaro A; Sabatino L; Macaluso A; Caldarella R; Caldara GF; Baldassano S · Nutrients · 2026
    Randomized trial35 participantsDetoxification forSelenium
  2. Meta-analysis: antioxidant supplements for liver diseases - the Cochrane Hepato-Biliary Group.
    Bjelakovic G; Gluud LL; Nikolova D; Bjelakovic M; Nagorni A; Gluud C · Alimentary pharmacology & therapeutics · 2011
    Meta-analysis1,225 participants20 studies pooledDetoxification forSelenium
  3. Exposure to a high selenium environment in Punjab, India: Effects on blood chemistry.
    Loomba R; Filippini T; Chawla R; Chaudhary R; Cilloni S; Datt C; Singh S; Dhillon KS; Vinceti M · The Science of the total environment · 2020
    Cross-sectional study680 participantsDetoxification forSelenium
  4. Supplementation with selenium can influence nausea, fatigue, physical, renal, and liver function of children and adolescents with cancer.
    Vieira ML; Fonseca FL; Costa LG; Beltrame RL; Chaves CM; Cartum J; Alves SI; Azzalis LA; Junqueira VB; Pereria EC; Rocha KC · Journal of medicinal food · 2015
    Randomized trialDetoxification forSelenium
  5. A short-term intervention trial with selenate, selenium-enriched yeast and selenium-enriched milk: effects on oxidative defence regulation.
    Ravn-Haren G; Bügel S; Krath BN; Hoac T; Stagsted J; Jørgensen K; Bresson JR; Larsen EH; Dragsted LO · The British journal of nutrition · 2008
    Randomized trialDetoxification forSelenium
  6. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  7. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  8. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  9. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  10. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  11. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  12. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  13. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  14. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  15. [Selenium and oxidative stress in cancer patients].
    Gorozhanskaia ÉG; Sviridova SP; Dobrovol'skaia MM; Zybrikhina GN; Kashnia ShR · Biomeditsinskaia khimiia · 2014
    Single-arm trial40 participantsDetoxification forSelenium
  16. Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study.
    Li C; Peng X; Zheng J; Shi K; Qin L; Yang Q; Wang Z; Liu Y; Huang L · Biological trace element research · 2024
    Other40 participantsDetoxification forSelenium
  17. Heavy metals and metalloids exposure and liver function in Chinese adults - A nationally representative cross-sectional study.
    Wang S; Lyu Y; Ji S; Liu N; Wu B; Zhao F; Li Z; Qu Y; Zhu Y; Xie L; Li Y; Zhang Z; Song H; Hu X; Qiu Y; Zheng X; Zhang W; Yang Y; Li F; Cai J; Zhu Y; Cao Z; Tan F; Shi X · Environmental research · 2024
    Cross-sectional study9,445 participantsDetoxification forSelenium
  18. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledGeneral Health forSelenium
  19. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledGeneral Health forSelenium
  20. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledGeneral Health forSelenium
  21. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsGeneral Health forSelenium
  22. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledGeneral Health forSelenium
  23. A review of complementary and alternative approaches to immunomodulation.
    Clarke JO; Mullin GE · Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2008
    Narrative reviewImmunity forResveratrol
  24. The role of dietary polyphenols in the management of inflammatory bowel disease.
    Farzaei MH; Rahimi R; Abdollahi M · Current pharmaceutical biotechnology · 2015
    Narrative reviewImmunity forResveratrol
  25. Complementary and alternative medicine: herbs, phytochemicals and vitamins and their immunologic effects.
    Mainardi T; Kapoor S; Bielory L · The Journal of allergy and clinical immunology · 2009
    Narrative reviewImmunity forResveratrol
  26. Resveratrol Treatment of Autism Spectrum Disorder-A Pilot Study.
    Marchezan J; Deckmann I; da Fonseca GC; Margis R; Riesgo R; Gottfried C · Clinical neuropharmacology · 2022
    Cohort study3 participantsImmunity forResveratrol
  27. Effects of resveratrol on inflammatory cytokines in COVID-19 patients: a randomized, double-blinded, placebo-controlled clinical trial.
    Bastin A; Netticadan T; Abbasi F; Rahimi N; Mahmoodi M; Alizadeh M; Movahed A; Momeni-Moghaddam MA · Molecular and cellular biochemistry · 2025
    Randomized trial44 participantsImmunity forResveratrol
  28. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  29. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  30. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  31. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  32. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium