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Centrum Multi+Beauty Multigummies

Centrum
4.6
★ ★ ★ ★ ★
(1260 ratings)
Iodine 150 mcg
Biotin 2500 mcg
Product Image
Score72
Biotin, vitamins A, C, D, and E, and zinc create a relevant beauty-focused nutrient base in a convenient gummy. Most nutrient forms are not identified, the gummy adds carbohydrate, and concentrated biotin can interfere with laboratory tests.
How scoring works
Quantity:100 Gummy(ies) • (50 servings)
Goals:
Nail Health
Energy
Hair Health
Skin Health

Score 72

Biotin, vitamins A, C, D, and E, and zinc create a relevant beauty-focused nutrient base in a convenient gummy. Most nutrient forms are not identified, the gummy adds carbohydrate, and concentrated biotin can interfere with laboratory tests.
How scoring works
$17.03($0.34 per serving)
Walmart
$ 19.49
iHerb
$ 17.03
iHerb
$ 17.03
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Analysis

Biotin, vitamins A, C, D, and E, and zinc create a relevant beauty-focused nutrient base in a convenient gummy. The format may improve adherence for people who dislike pills.

The formula covers more nutritional pathways than biotin alone. Most nutrient forms are not identified, the gummy adds carbohydrate, and concentrated biotin can interfere with laboratory tests.

It suits adults who prioritize taste and convenience over form transparency. Users managing carbohydrates or preparing for blood tests need a different approach.

Who is it for
  • It suits adults who prioritize taste and convenience over form transparency
  • Adults seeking the product’s stated nutrient profile
Best for
  • The format may improve adherence for people who dislike pills
  • Users managing carbohydrates or preparing for blood tests need a different approach

Pros

  • Broad beauty-focused nutrients
  • Includes zinc
  • Convenient gummy format
  • Easy once-daily routine

Cons

  • Most nutrient forms are unspecified
  • Adds carbohydrate
  • Biotin amount is high
  • Gummy format limits mineral density

Warnings

  • Biotin can interfere with thyroid, hormone, cardiac troponin, and other laboratory tests; follow laboratory guidance before testing.
  • Preformed vitamin A should be counted carefully during pregnancy and when stacking other vitamin A products.
  • Keep gummies away from children because the candy-like format can encourage overconsumption.

Nutrient quality

65 High impact

High biotin and selected vitamins fit beauty-focused nutrition. Missing forms and the lack of structural hair, skin, or nail actives limit formula depth.

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Ingredient transparency

73 High impact

Active amounts are clear and no proprietary blend is shown. Gummy-base ingredients, complete directions, and many nutrient forms are missing.

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Customer satisfaction

69 High impact

The supplied average is favorable, and the rating count is large. Specific firsthand feedback is absent, so repeated complaints and purpose fit cannot be assessed.

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Value for money

83 Highest impact

The serving cost is favorable for the disclosed ingredient quality and purpose. A few weak or unrelated additions modestly reduce efficiency.

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Report analysis

Goals

Nail Health
Impact
High effect
B- Goal FitB Strength of SupportC+ CoverageB- Formula Quality
Biotin · 2500 mcg

Biotin, zinc, vitamin C, and broad micronutrients support nail growth when dietary gaps contribute to weakness. The biotin amount is substantial, while zinc and vitamin C add useful secondary support.

No collagen, keratin, silicon, or sulfur amino acid provides direct structural building material. The gummy format adds carbohydrate and favors breadth over deep structural support.

Study evidence
Biotin Supportive 8 studies
Vitamin C Supportive 1 study
Zinc No effect 1 study
Energy
Impact
High effect
B+ Goal FitC- Strength of SupportC- CoverageB- Formula Quality
Iodine · 150 mcgVitamin D · 25 mcgVitamin B5 · 6 mgVitamin B12 · 15 mcg

B vitamins and iodine support metabolic and thyroid pathways, but their amounts favor general maintenance rather than focused energy support. The formula lacks iron, magnesium, caffeine, or an adaptogen for a stronger functional effect.

Its gummy design and very high biotin emphasis fit beauty positioning more than energy performance. Unspecified nutrient forms further limit confidence in absorption quality.

Study evidence
Iodine Adverse 3 studies
Hair Health
Impact
Moderate effect
C Goal FitB- Strength of SupportC- CoverageC Formula Quality
Biotin · 2500 mcgVitamin D · 25 mcgZinc · 5 mgVitamin C · 45 mg

Biotin, zinc, vitamin D, vitamin C, and vitamin A provide a wider nutrient base than biotin alone. Benefits are still most plausible when a nutritional shortfall contributes to weak hair or shedding.

The main amounts are disclosed, though many forms are not specified and the gummy adds carbohydrate. The 2,500 mcg biotin dose can interfere with some laboratory tests, so its use should be disclosed before blood work.

Study evidence
Biotin Supportive 4 studies
Vitamin A Disputed 13 studies
Vitamin C Mixed 5 studies
Vitamin D Disputed 34 studies
Zinc Supportive 22 studies
Skin Health
Impact
Moderate effect
C- Goal FitC+ Strength of SupportC CoverageC- Formula Quality
Zinc · 5 mgVitamin C · 45 mgVitamin E · 13.5 mg

Biotin with vitamins A, C, and E and zinc supports several aspects of normal skin maintenance. The formula covers cell turnover, collagen cofactors, antioxidant defense, and repair.

Biotin evidence is strongest for deficiency, while the other nutrients are general maintenance support rather than targeted skin actives. The high biotin amount may interfere with some thyroid, hormone, and cardiac laboratory tests, so testing professionals should be told about its use.

Study evidence
Biotin Supportive 10 studies
Zinc Supportive 66 studies

Ingredients

IngredientAmount per serving
Calories
20 Calorie(s)
Total Carbohydrates
4 Gram(s)
Vitamin A
750 mcg
Vitamin C
45 mg
Vitamin D3
25 mcg
Vitamin E
13.5 mg
Vitamin B6
5 mg
Folate
267 mcg DFE
Vitamin B12
15 mcg
Biotin
2500 mcg
Pantothenic Acid
6 mg
Calcium
130 mg
Iodine
150 mcg
Zinc
5 mg
Sodium
5 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Iodine · 150 mcg OverallScore75
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
The iodine chemical form or source is not identified, limiting confidence in bioavailability. 150 mcg fits the optimal daily-support range. The label clearly states the active iodine amount. Per-serving cost falls in the very low-cost tier without a qualifying cofactor adjustment.
Biotin · 2500 mcg OverallScore69
C- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyC Value

Biotin is supplied at 2,500 mcg, providing a moderately high amount for hair and nail support. The broader formula adds co-factors, while the exact biotin amount remains clearly disclosed. High-dose biotin can interfere with some laboratory tests, so users should disclose use before blood testing.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Nail Health Skin Health forBiotin
  2. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  3. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health Skin Health forBiotin
  4. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  5. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy.
    Colombo VE; Gerber F; Bronhofer M; Floersheim GL · Journal of the American Academy of Dermatology · 1991
    Other32 participantsNail Health forBiotin
  6. Biotin for the treatment of nail disease: what is the evidence?
    Lipner SR; Scher RK · The Journal of dermatological treatment · 2018
    Narrative reviewNail Health forBiotin
  7. Brittle nails: response to daily biotin supplementation.
    Hochman LG; Scher RK; Meyerson MS · Cutis · 1993
    Case series35 participantsNail Health forBiotin
  8. Vitamins and minerals: their role in nail health and disease.
    Scheinfeld N; Dahdah MJ; Scher R · Journal of drugs in dermatology : JDD · 2007
    Narrative reviewNail Health forBiotin Nail Health forZinc
  9. Nail Supplements: When, How, and Why?
    Zaraa I; Richert B · Skin appendage disorders · 2026
    Narrative reviewNail Health forBiotin
  10. Brittle nails.
    Iorizzo M; Pazzaglia M; M Piraccini B; Tullo S; Tosti A · Journal of cosmetic dermatology · 2009
    Narrative reviewNail Health forBiotin
  11. Association of radioactive iodine treatment with survivorship symptoms and primary care utilisation in women of reproductive age with thyroid cancer: a retrospective cohort study.
    Devanarayan P; Hartman M; Partin M · Family medicine and community health · 2026
    Cohort study10,882 participantsEnergy forIodine
  12. Energy level and fatigue after surgery for thyroid cancer: A population-based study of patient-reported outcomes.
    Hughes DT; Reyes-Gastelum D; Kovatch KJ; Hamilton AS; Ward KC; Haymart MR · Surgery · 2020
    Cohort study2,584 participantsEnergy forIodine
  13. Health-Related Quality of Life in Differentiated Thyroid Cancer Survivors: A Cross-Sectional Study From Turkey.
    Gültekin A; Kahraman MY; Şengöz T; Şimşek FS · Head & neck · 2026
    Cross-sectional study202 participantsEnergy forIodine
  14. Topical tretinoin for hair growth promotion.
    Bazzano GS; Terezakis N; Galen W · Journal of the American Academy of Dermatology · 1986
    Non-randomized trial56 participantsHair Health forVitamin A
  15. A review of isotretinoin in the treatment of frontal fibrosing alopecia.
    Shahpar A; Nezhad NZ; Sahaf AS; Ahramiyanpour N · Journal of cosmetic dermatology · 2024
    Systematic review232 participants15 studies pooledHair Health forVitamin A
  16. Efficacy of Isotretinoin and Acitretin in Treatment of Frontal Fibrosing Alopecia: Retrospective Analysis of 54 Cases.
    Rakowska A; Gradzińska A; Olszewska M; Rudnicka L · Journal of drugs in dermatology : JDD · 2018
    Cohort study54 participantsHair Health forVitamin A
  17. Systemic Treatments for Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective Study of 315 Patients.
    Willaert M; Van Dongen T; Dikrama P; Nijsten T; Hijnen D; Waalboer-Spuij R · Acta dermato-venereologica · 2025
    Cohort study315 participantsHair Health forVitamin A
  18. Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes.
    Sharma A; Goren A; Dhurat R; Agrawal S; Sinclair R; Trüeb RM; Vañó-Galván S; Chen G; Tan Y; Kovacevic M; Situm M; McCoy J · Dermatologic therapy · 2020
    Single-arm trialHair Health forVitamin A
  19. Management of hair loss associated with endocrine therapy in patients with breast cancer: an overview.
    Karatas F; Sahin S; Sever AR; Altundag K · SpringerPlus · 2016
    Narrative reviewHair Health forVitamin C
  20. Elucidating causal relationships of diet-derived circulating antioxidants and the risk of non-scarring alopecia: A Mendelian randomization study.
    Ba Y; Shen L; Peng X; Zhang Y; Wang J · Medicine · 2024
    Methods validation study201,019 participantsHair Health forVitamin C
  21. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers.
    Liu CS; Chen HW; Lii CK; Tsai CS; Kuo CL; Wei YH · Environmental and molecular mutagenesis · 2002
    Observational studyHair Health forVitamin C
  22. Removal of synthetic hair dye using formamidine sulfinic acid and other sulfinate precursors.
    Hawkes JA; Lewis DM; Mama J; Murray J · International journal of cosmetic science · 2026
    Methods validation studyHair Health forVitamin C
  23. A Zinc Sulphate-Resistant Acrodermatitis Enteropathica Patient with a Novel Mutation in SLC39A4 Gene.
    Kilic M; Taskesen M; Coskun T; Gürakan F; Tokatli A; Sivri HS; Dursun A; Schmitt S; Küry S · JIMD reports · 2013
    Case reportHair Health forVitamin C
  24. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  25. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  26. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  27. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  28. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  29. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  30. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  31. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  32. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  33. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  34. Treatment of brittle nail with a hydroxypropyl chitosan-based lacquer, alone or in combination with oral biotin: A randomized, assessor-blinded trial.
    Chiavetta A; Mazzurco S; Secolo MP; Tomarchio G; Milani M · Dermatologic therapy · 2020
    Randomized trial50 participantsNail Health forBiotin
  35. Vitamin C Deficiency in Inflammatory Bowel Disease: The Forgotten Micronutrient.
    Dunleavy KA; Ungaro RC; Manning L; Gold S; Novak J; Colombel JF · Crohn's & colitis 360 · 2023
    Other20 participantsNail Health forVitamin C
  36. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
    Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
    Non-randomized trial60 participantsSkin Health forBiotin
  37. Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
    Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
    Non-randomized trial25 participantsSkin Health forBiotin
  38. Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
    Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
    Case series4 participantsSkin Health forBiotin
  39. Sex-related differences in response to zinc pyrithione shampoo vs. non-anti-dandruff shampoo.
    Collins LZ; Baines FL; Matheson JR; Turner GA; Diao Y; Li Y; Pi Y · International journal of cosmetic science · 2019
    Meta-analysis2,088 participants20 studies pooledSkin Health forZinc
  40. Maintenance of an Acidic Skin Surface with a Novel Zinc Lactobionate Emollient Preparation Improves Skin Barrier Function in Patients with Atopic Dermatitis.
    Andrew PV; Pinnock A; Poyner A; Brown K; Chittock J; Kay LJ; Cork MJ; Danby SG · Dermatology and therapy · 2024
    Cohort study23 participantsSkin Health forZinc
  41. Spatial expression of metallothionein, matrix metalloproteinase-1 and Ki-67 in human epidermal wounds treated with zinc and determined by quantitative immunohistochemistry: A randomised double-blind trial.
    Ågren MS; Chafranska L; Eriksen JO; Forman JL; Bjerrum MJ; Schjerling P; Larsen HF; Cottarelli E; Jorgensen LN; Gjerdrum LMR · European journal of cell biology · 2021
    Randomized trial30 participantsSkin Health forZinc
  42. A pilot trial using topical regular crystalline insulin vs. aqueous zinc solution for uncomplicated cutaneous wound healing: Impact on quality of life.
    Attia EA; Belal DM; El Samahy MH; El Hamamsy MH · Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2014
    Randomized trial90 participantsSkin Health forZinc
  43. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forZinc