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Pantothenic Acid 500 mg

Solaray
4.7
★ ★ ★ ★ ★
(4544 ratings)
Vitamin B5 500 mg
Product Image
Score79
A focused high vitamin B5 supplement in a stable form, with digestive tolerance and narrow coverage as the main trade-offs.
How scoring works
Quantity:100 VegCap(s) • (100 servings)
Goals:
Skin Health

Score 79

A focused high vitamin B5 supplement in a stable form, with digestive tolerance and narrow coverage as the main trade-offs.
How scoring works

Also available as

1 option
250 servings B5 500 mg • 250 VegCap(s) • 250 servings $29.69 ($0.11 per serving)
$14.49($0.14 per serving)
Pure Formulas
$ 14.49
iHerb
$ 14.49
Amazon
$ 14.49
Vitacost
$ 14.49
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Analysis

Calcium pantothenate is a stable, well-used form of vitamin B5, and the active amount is stated clearly. A single-ingredient design makes the purpose easy to understand and avoids an opaque blend.

High isolated vitamin B5 is more intensive than most people need for basic nutritional coverage. Separate calcium or repeated pantothenic acid entries add label clutter without meaningfully broadening the formula.

Good serving value supports focused use, but tolerance matters more than label potency at this level. The product does not include collagen, barrier lipids, zinc, or other ingredients that would create broad skin support.

Who is it for
  • Adults seeking isolated vitamin B5
  • Users who prefer a simple single-active formula
Best for
  • Focused vitamin B5 within a skin routine
  • Vegetarian capsule convenience

Pros

  • Stable calcium pantothenate form
  • Clearly stated active amount
  • Simple focused formula

Cons

  • Amount is aggressive for basic coverage
  • No broader B-complex support
  • Repeated entries reduce label clarity

Warnings

  • High-dose pantothenic acid may cause stomach discomfort or loose stools in sensitive users.

Nutrient quality

83 Highest impact

Calcium pantothenate is a stable, well-regarded vitamin B5 form. The 500 mg amount is meaningful for targeted vitamin B5 use.

.

Ingredient transparency

81 Highest impact

Active ingredients and their amounts are clearly listed without a hidden blend. Other ingredients and complete intake directions are not supplied, which leaves important label details unresolved.

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Customer satisfaction

65 Moderate impact

The supplied average rating is strong and the rating volume is sufficient for a broad signal. No comment-level evidence is provided to assess recurring complaints or confirm how experience matches the intended purpose.

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Value for money

85 Highest impact

The ingredient form and dose provide reasonable utility, though serving value is only moderate. The supplied active formula is not inflated by obvious low-value extras.

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Goals

Skin Health
Skin Health
Impact
Moderate effect
D- Goal FitC+ Strength of SupportF CoverageA Formula Quality

Pantothenic acid has a nutritional role in skin metabolism, but evidence for improving normal skin at high doses is limited. It does not directly supply collagen, barrier lipids, or a proven photoprotective active.

The 500 mg amount is far above nutritional needs without a clear skin-dose advantage. That amount may cause diarrhea or other digestive discomfort in sensitive users.

Study evidence
Vitamin B5 Supportive 11 studies

Ingredients

IngredientAmount per serving
Pantothenic Acid (Calcium D-Pantothenate)
 500 mg
Calcium (Calcium D-Pantothenate)
 45 mg
Adults 18–50
Report overview
Vitamin B5 (Calcium D-Pantothenate) · 500 mg OverallScore91
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The formula delivers a high dose of well-absorbed calcium D-pantothenate with clear labeling. Its vegetable capsule and concentrated serving provide good dose-adjusted value for targeted vitamin B5 use. The 500 mg dose may cause digestive upset in sensitive users and may be unnecessary for routine maintenance.

View ingredientView products
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84 Performance

Pantothenic Acid 500 mg

Solaray
<p>Calcium D-pantothenate supplies a very high vitamin B5 amount in a simple capsule at a low serving cost. Compared with Pantothenic Acid 500 mg, its disclosed vitamin B5 form and overall formulation may be a better fit where the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users, although the form and active amount are clear, but the dose far exceeds basic nutritional needs and evidence for a skin benefit at this level is limited.</p>
81 Performance

Pantothenic Acid B5 500 mg

Jarrow Formulas
<p>Calcium pantothenate supplies a suitable vitamin B5 form at a clearly stated amount. Compared with Pantothenic Acid 500 mg, its disclosed vitamin B5 form and overall formulation may be a better fit where the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users, although the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users.</p>
81 Performance

Pantothenic Acid (Vitamin B-5) 500 mg

Life Extension
<p>Calcium pantothenate supplies a suitable vitamin B5 form at a clearly stated amount. Compared with Pantothenic Acid 500 mg, its disclosed vitamin B5 form and overall formulation may be a better fit where the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users, although the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users.</p>
85 Budget

Pantothenic Acid 100 mg

Source Naturals
<p>Calcium D-pantothenate supplies a useful, clearly disclosed vitamin B5 amount in a simple one-tablet formula. Its lower recurring cost than Pantothenic Acid 500 mg makes it the more economical choice while retaining the stated vitamin B5 support, although the dose is well suited to focused maintenance use and carries little concern about unnecessary excess.</p>
81 Budget

Pantothenic Acid 500 mg

NOW
<p>Calcium pantothenate supplies a suitable vitamin B5 form at a clearly stated amount. Its lower recurring cost than Pantothenic Acid 500 mg makes it the more economical choice while retaining the stated vitamin B5 support, although the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users.</p>
81 Budget

Pantothenic Acid 250 mg

Swanson Premium Brand
<p>Calcium pantothenate supplies a suitable vitamin B5 form at a clearly stated amount. Its lower recurring cost than Pantothenic Acid 500 mg makes it the more economical choice while retaining the stated vitamin B5 support, although the focused formula avoids low-value active additions.</p>
85 Value

Pantothenic Acid 250 mg

Source Naturals
<p>Calcium D-pantothenate supplies a strong, clearly disclosed vitamin B5 amount in a simple one-tablet formula. Compared with Pantothenic Acid 500 mg, its vitamin B5 profile and lower recurring cost create a more favorable quality-to-cost balance, although the form is stable and well absorbed, while the dose is substantial without being the most aggressive option in this group.</p>
81 Value

Pantothenic Acid 550 mg

Solgar
<p>Calcium pantothenate supplies a suitable vitamin B5 form at a clearly stated amount. Compared with Pantothenic Acid 500 mg, its vitamin B5 profile and lower recurring cost create a more favorable quality-to-cost balance, although the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users.</p>
78 Value

Pantothenic Acid 500 mg

Bluebonnet
<p>Calcium pantothenate supplies a suitable vitamin B5 form at a clearly stated amount. Compared with Pantothenic Acid 500 mg, its vitamin B5 profile creates a practical quality-to-cost trade-off despite not costing less, although the high amount may be unnecessary for routine maintenance and can cause digestive discomfort in sensitive users.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. A randomized, double-blind, placebo-controlled study of a novel pantothenic Acid-based dietary supplement in subjects with mild to moderate facial acne.
    Yang M; Moclair B; Hatcher V; Kaminetsky J; Mekas M; Chapas A; Capodice J · Dermatology and therapy · 2014
    Randomized trial48 participantsSkin Health forVitamin B5
  2. Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation.
    Proksch E; Nissen HP · The Journal of dermatological treatment · 2009
    Randomized trialSkin Health forVitamin B5
  3. Comparative trial of 5% dexpanthenol in water-in-oil formulation with 1% hydrocortisone ointment in the treatment of childhood atopic dermatitis: a pilot study.
    Udompataikul M; Limpa-o-vart D · Journal of drugs in dermatology : JDD · 2012
    Non-randomized trial30 participantsSkin Health forVitamin B5
  4. Panthenol Allergic Contact Dermatitis: Sources of Exposure, Reported Cases, and a Call for More Frequent Testing.
    Weber B; Hylwa S · Dermatitis : contact, atopic, occupational, drug · 2025
    Narrative reviewSkin Health forVitamin B5
  5. Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd).
    EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP); Villa RE; Azimonti G; Bonos E; Christensen H; Durjava M; Dusemund B; Gehring R; Glandorf B; Kouba M; López-Alonso M; Marcon F; Nebbia C; Pechová A; Prieto-Maradona M; Röhe I; Theodoridou K; Galobart J; Holczknecht O; Pizzo F; Radovnikovic A; Vettori MV; Amaduzzi A · EFSA journal. European Food Safety Authority · 2025
    Guideline / consensusSkin Health forVitamin B5
  6. Panthenyl triacetate transformation, stimulation of metabolic pathways, and wound-healing properties in the human skin.
    Dell'Acqua G; Schweikert K · Journal of cosmetic science · 2012
    Randomized trialSkin Health forVitamin B5
  7. Dexpanthenol modulates gene expression in skin wound healing in vivo.
    Heise R; Skazik C; Marquardt Y; Czaja K; Sebastian K; Kurschat P; Gan L; Denecke B; Ekanayake-Bohlig S; Wilhelm KP; Merk HF; Baron JM · Skin pharmacology and physiology · 2013
    Clinical trialSkin Health forVitamin B5