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Vitamin C 1000 mg

4.8
★ ★ ★ ★ ★
(3268 ratings)
Vitamin C 1000 mg
Product Image
Score82
A potent, large-count vitamin C capsule with good value and a simple label. Unbuffered acidity and the fixed high amount limit its fit for sensitive users.
How scoring works
Capsule
Quantity:250 Capsule(s) • (250 servings)
Goals:
General Health
Skin Health
Immunity
Anti-Inflammatory Support
Vision Support

Score 82

A potent, large-count vitamin C capsule with good value and a simple label. Unbuffered acidity and the fixed high amount limit its fit for sensitive users.
How scoring works
$31.51($0.12 per serving)
iHerb
$ 31.51
Vitacost
$ 33.53
Daily Vita
$ 37.12
Vitacost
$ 33.53
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Analysis

The L-ascorbic acid serving provides substantial antioxidant, immune, and collagen support. Its focused composition is easy to understand but offers no complementary flavonoids or broader pathway coverage.

Capsule delivery avoids gummy sugar and acidic contact with the teeth. The active is still unbuffered, and no enhanced absorption feature or complete inactive-ingredient profile is supplied.

The large bottle gives regular users favorable value without adding formulation complexity. It is a less suitable first choice for people who want smaller servings or better digestive comfort.

Who is it for
  • Regular high-potency vitamin C users
  • People who prefer capsules
  • Shoppers seeking a large supply
Best for
  • Immune support
  • Antioxidant support
  • Long-term basic supplementation

Pros

  • Clearly stated 1,000 mg serving
  • Good value in a large count
  • Simple capsule format

Cons

  • No buffering
  • No complementary ingredients
  • Complete excipient details are not provided

Warnings

  • The full serving may cause nausea or loose stools in sensitive users.
  • Unbuffered L-ascorbic acid can aggravate an acid-sensitive stomach.
  • The fixed high serving offers less flexibility for gradual dose adjustment.

Nutrient quality

83 Highest impact

Ascorbic acid is established but has no stated buffering or enhanced-delivery feature. The substantial vitamin C serving is sufficient for focused supplementation.

Ingredient transparency

83 Highest impact

All listed active amounts are disclosed without a proprietary blend. Complete directions and inactive-ingredient details remain incomplete.

Customer satisfaction

73 High impact

The aggregate rating and its volume provide a favorable top-level signal. Missing experience details prevent assessment of repeated complaints or purpose-specific satisfaction.

Value for money

88 Highest impact

A substantial serving and large package support favorable category value. Incomplete additive detail limits a stronger conclusion.

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Goals

General Health
Impact
Highest effect
A Goal FitA Strength of SupportC CoverageA+ Formula Quality
Vitamin C · 1000 mg

Vitamin C supports antioxidant protection, immune function, and collagen synthesis. The 1,000 mg L-ascorbic acid serving is substantial and clearly disclosed.

The single-vitamin format does not address other foundational nutrient gaps. Its streamlined design still provides strong depth for targeted vitamin C support.

Study evidence
Vitamin C Supportive 56 studies
Skin Health
Impact
Highest effect
B+ Goal FitA Strength of SupportC+ CoverageA Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports collagen formation and antioxidant protection in skin. Human evidence supports these roles, although oral vitamin C alone does not address hydration or barrier lipids.

The high, clearly labeled amount provides ample nutritional support, and the ascorbic-acid form is well established. The small rose-hip addition is not needed for the main benefit but does not materially dilute the formula.

Study evidence
Vitamin C Supportive 53 studies
Immunity
Impact
Highest effect
A Goal FitA- Strength of SupportC CoverageA Formula Quality
Vitamin C · 1000 mg

The 1,000 mg L-ascorbic acid serving provides direct antioxidant and immune-cell support at a substantial dose. The single-active formula is transparent and avoids weak add-on ingredients.

Plain ascorbic acid lacks the stomach-comfort advantage of a buffered form and offers no enhanced-delivery feature. The high dose may cause digestive upset, and people prone to calcium oxalate kidney stones should consider their total vitamin C intake.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Impact
High effect
C Goal FitA+ Strength of SupportD CoverageA+ Formula Quality
Vitamin C · 1000 mg

Vitamin C provides antioxidant support that can help control oxidative stress linked to inflammatory signaling. It is a supportive nutrient rather than a direct broad-spectrum anti-inflammatory agent.

The 1,000 mg L-ascorbic acid amount is fully disclosed and substantial. That amount may cause diarrhea or stomach cramps and may raise kidney-stone risk in susceptible users.

Study evidence
Vitamin C Supportive 50 studies
Vision Support
Impact
High effect
C Goal FitA Strength of SupportD CoverageA+ Formula Quality
Vitamin C · 1000 mg

Vitamin C provides substantial antioxidant support relevant to the lens and ocular tissues. Used alone, it does not supply the carotenoids, zinc, vitamin E, copper, or omega-3s found in broader vision formulas.

L-ascorbic acid and its exact amount are fully disclosed. The product offers strong depth in one narrow pathway.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (L-Ascorbic Acid)
1000 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
F Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyB+ Value

A clearly disclosed 1,000 mg serving meets the efficient dose target. The unbuffered L-ascorbic acid form offers no stated absorption or stomach-comfort advantage. Cost per gram is good, while inactive-ingredient detail remains incomplete in the supplied data.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  2. Serum vitamin C and spinal pain: a nationwide study.
    Dionne CE; Laurin D; Desrosiers T; Abdous B; Le Sage N; Frenette J; Mondor M; Pelletier S · Pain · 2017
    Cross-sectional study4,742 participantsGeneral Health forVitamin C
  3. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  4. Immunocompetence and oxidant defense during ascorbate depletion of healthy men.
    Jacob RA; Kelley DS; Pianalto FS; Swendseid ME; Henning SM; Zhang JZ; Ames BN; Fraga CG; Peters JH · The American journal of clinical nutrition · 1992
    Clinical trial8 participantsImmunity forVitamin C
  5. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  6. Association between hemoglobin A1c, Vitamin C, and microbiome in diabetic foot ulcers and intact skin: A cross-sectional study.
    Tong KPS; Green SJ; Ortiz J; Wu SC · Health science reports · 2024
    Cross-sectional study42 participantsSkin Health forVitamin C
  7. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  8. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  9. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  10. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  11. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  12. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  13. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  14. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  15. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  16. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  17. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  18. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  19. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  20. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  21. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  22. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  23. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  24. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  25. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  26. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  27. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  28. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C