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Mild-C 1600 mg

4.6
★ ★ ★ ★ ★
(102 ratings)
Vitamin C 1600 mg
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Score87
A high-value buffered powder with flexible dosing and clear mineral disclosure. The full serving is large and may be better divided.
How scoring works
Powder
Quantity:35 Ounce(s) • (500 servings)
Goals:
Immunity
General Health
Skin Health
Anti-Inflammatory Support

Score 87

A high-value buffered powder with flexible dosing and clear mineral disclosure. The full serving is large and may be better divided.
How scoring works
$63.01($0.12 per serving)
iHerb
$ 63.01
Vitacost
$ 89.25
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Analysis

Calcium ascorbate supplies substantial vitamin C in a fully buffered form that may be gentler than plain ascorbic acid. Separate disclosure of the calcium contribution makes the active profile easy to understand.

The powder format allows users to adjust or divide the serving instead of taking the full amount at once. That flexibility is useful because the listed full serving is above what many people need for routine supplementation.

Formula breadth remains limited despite the added calcium, with no targeted carotenoids, lipids, or other immune nutrients. It best fits users who want bulk buffered vitamin C and are comfortable measuring powder accurately.

Who is it for
  • Users seeking buffered vitamin C powder
  • People with stomach sensitivity to plain ascorbic acid
  • Adults who prefer adjustable serving sizes
Best for
  • Flexible vitamin C dosing
  • High-volume routine use
  • Buffered antioxidant support

Pros

  • Fully buffered calcium ascorbate
  • Powder supports adjustable portions
  • Vitamin C and calcium amounts are both disclosed

Cons

  • Full serving exceeds many routine needs
  • Powder requires accurate measuring
  • Little support beyond the vitamin C pathway

Warnings

  • The full serving may cause digestive upset or loose stools despite buffering
  • Measure the powder carefully because the listed serving is highly concentrated
  • People prone to calcium oxalate kidney stones should be cautious with sustained high supplemental intake

Nutrient quality

86 Highest impact

Buffered vitamin C and its associated calcium fit the focused purpose. The large serving approaches the adult upper intake level and may be unnecessarily aggressive for routine use.

Ingredient transparency

93 Highest impact

Both vitamin C and elemental calcium amounts are disclosed. The supplied data do not show a complete inactive-ingredient statement.

Customer satisfaction

66 High impact

The supplied aggregate rating indicates strong satisfaction. No complaint text is supplied, so repetitive negative themes cannot be assessed.

Value for money

97 Highest impact

The powder provides a meaningful serving at a very low relative cost. The focused active profile avoids low-value extras.

Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A Goal FitA- Strength of SupportC CoverageA+ Formula Quality
Vitamin C · 1600 mg

Buffered vitamin C directly supports immune-cell function, epithelial barriers, and antioxidant control. Its single-nutrient scope is narrow, but the calcium ascorbate form is well suited to sensitive stomachs.

The 1,600 mg amount is above the preferred range and may be more than needed at once. A measured powder allows the serving to be split, and the exact vitamin C plus calcium contributions are clearly disclosed.

Study evidence
Vitamin C Supportive 53 studies
General Health
General Health
Impact
Highest effect
A- Goal FitB+ Strength of SupportC+ CoverageA Formula Quality
Vitamin C · 1600 mg

Buffered calcium ascorbate offers a stomach-friendly way to obtain substantial vitamin C support. Both vitamin C and calcium amounts are clearly disclosed, and the powder allows flexible serving adjustment.

The full serving exceeds what is generally needed for efficient routine intake, so a smaller portion may be more practical. Its single-pathway focus is deep and clean but does not cover broader nutritional gaps.

Study evidence
Vitamin C Supportive 56 studies
Skin Health
Skin Health
Impact
High effect
B- Goal FitB+ Strength of SupportD+ CoverageA Formula Quality
Vitamin C · 1600 mg

Buffered vitamin C provides direct collagen-cofactor and antioxidant support in a simple powder. The formula is focused but does not address skin hydration, barrier lipids, or structural collagen intake.

The calcium ascorbate form is clearly disclosed and should be gentler than plain ascorbic acid. The large single serving exceeds what most users need at once and may cause digestive upset or add little benefit beyond a smaller divided dose.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Cellular Defense
Anti-Inflammatory Support
Impact
High effect
C+ Goal FitC+ Strength of SupportD+ CoverageA Formula Quality
Vitamin C · 1600 mg

Buffered calcium ascorbate supplies a large antioxidant dose with good gastric tolerance. The amount may support oxidative balance, but it exceeds the preferred efficient range for a single serving.

Clear disclosure of vitamin C and calcium makes the powder easy to assess. Dividing the serving may provide a more balanced intake while the formula remains narrow in pathway coverage.

Study evidence
Vitamin C Supportive 50 studies
Vision Support
Vision Support
Impact
Moderate effect
D- Goal FitA- Strength of SupportD- CoverageC Formula Quality
Vitamin C · 1600 mg

Vitamin C provides antioxidant support relevant to ocular tissues, but no lutein, zeaxanthin, zinc, dha, or vitamin e is included. A 1,600 mg serving provides a meaningful vitamin C amount, but it does not supply the core carotenoids or structural lipids used for targeted vision support.

The product addresses only water-soluble antioxidant defense and does not cover macular pigment or retinal lipid pathways. The simple vitamin C design is internally coherent for antioxidant supplementation.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Calcium Ascorbate)
 1600 mg
Calcium (Calcium Ascorbate)
 180 mg
Gluten Free Adults 18–50
Report overview
Vitamin C (Calcium Ascorbate) · 1600 mg OverallScore83
B+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA+ Value

Fully buffered calcium ascorbate supports gastric comfort and has excellent source transparency. The 1,600 mg serving exceeds the preferred range, so splitting the powder may offer a more efficient intake. Exceptional cost per gram is a major advantage for users who specifically want a buffered form.

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89 Performance

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<p>The ingredient profile is a stronger fit for focused vitamin C support, supplying 1000 mg of vitamin C as Ester-C with calcium and citrus bioflavonoids. The added bioflavonoids broaden the formula beyond the original’s Calcium Ascorbate-focused ingredient profile.</p>
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<p>The ingredient profile is a stronger fit for focused vitamin C support, supplying 1000 mg of vitamin C as Calcium Ascorbate with calcium and citrus bioflavonoids. The added bioflavonoids broaden the formula beyond the original’s Calcium Ascorbate-focused ingredient profile.</p>
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<p>A lower cost per serving makes this a practical budget alternative, while it supplies 890 mg of vitamin C as Calcium Ascorbate with calcium. The 890 mg amount is lower than the original's 1600 mg serving, so the trade-off is less vitamin C per serving.</p>
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<p>A lower cost per serving makes this a practical budget alternative, while it supplies 1100 mg of vitamin C as Sodium Ascorbate. The 1100 mg amount is lower than the original's 1600 mg serving, so the trade-off is less vitamin C per serving.</p>
87 Budget

100% Pure Vitamin C Powder

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<p>A lower cost per serving makes this a practical budget alternative, while it supplies 1000 mg of vitamin C as Ascorbic Acid. The 1000 mg amount is lower than the original's 1600 mg serving, so the trade-off is less vitamin C per serving.</p>
93 Value

Pure Buffered Magnesium Ascorbate

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<p>Strong serving value is paired with 820 mg of vitamin C as Magnesium Ascorbate with magnesium. It uses a lower vitamin C amount than the original and keeps the active formula clearly disclosed, balancing cost-effectiveness with a useful ingredient profile.</p>
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<p>Strong serving value is paired with 850 mg of vitamin C as Sodium Ascorbate. It uses a lower vitamin C amount than the original and keeps the active formula clearly disclosed, balancing cost-effectiveness with a useful ingredient profile.</p>
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<p>Strong serving value is paired with 1000 mg of vitamin C as Ester-C Calcium Ascorbate with calcium and citrus bioflavonoids. It uses a lower vitamin C amount than the original and adds disclosed bioflavonoids, balancing cost-effectiveness with a useful ingredient profile.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  2. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  3. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  4. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  5. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  6. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  7. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  8. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  9. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  10. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  11. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  12. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  13. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  14. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  15. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  16. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  17. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  18. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  19. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  20. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  21. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  22. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  23. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  24. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  25. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C