Product Image

Healthy Fat Burner

Terra Origin
4.6
★ ★ ★ ★ ★
(1635 ratings)
Acetyl L-Carnitine 500 mg
Choline 20 mg
Tyrosine 200 mg
Ginger
Green Tea 50 mg
Product Image
Score63
A stimulant-led energy formula with a useful acetyl-L-carnitine dose, offset by underdosed extras and a demanding combination of sympathomimetic ingredients.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Energy
Metabolism Boost
Mental Focus
Cognitive Support
Brain Health
Productivity Boost
Weight Loss

Score 63

A stimulant-led energy formula with a useful acetyl-L-carnitine dose, offset by underdosed extras and a demanding combination of sympathomimetic ingredients.
How scoring works
$19.99($0.66 per serving)
Amazon
$ 19.99
iHerb
$ 19.99
Report prices

Analysis

Acetyl-L-carnitine is the best-supported part of the formula, with a clearly stated amount suited to a combination product. Caffeine adds dependable stimulation, while the tyrosine and choline amounts are too low to drive strong cognitive effects on their own.

The long ingredient list suggests broad metabolism support, but green tea, ginger, garcinia, and several other components are lightly dosed or not standardized. That makes the formula more reliant on stimulants than its varied label may imply.

Bitter orange, yohimbine, hordenine, and caffeine can produce overlapping stimulant effects. The product may suit experienced stimulant users, but it is difficult to recommend for anyone prone to anxiety, elevated heart rate, blood-pressure changes, or sleep disruption.

Who is it for
  • Experienced stimulant users seeking energy support
  • Adults who value acetyl-L-carnitine in a combination formula
Best for
  • Daytime energy
  • Metabolism-oriented supplementation
  • Workout alertness

Pros

  • Useful acetyl-L-carnitine amount
  • Caffeine amount is clearly disclosed
  • Individual ingredient amounts are listed

Cons

  • Many secondary ingredients are lightly dosed
  • Green tea lacks active-marker standardization
  • Choline and tyrosine amounts are low
  • Complex stimulant stack reduces predictability

Warnings

  • Caffeine, bitter orange, yohimbine, and hordenine may collectively increase anxiety, heart rate, or blood pressure.
  • Avoid combining with other stimulants and avoid taking close to bedtime.
  • People with cardiovascular concerns or marked stimulant sensitivity should avoid this formula unless a clinician advises otherwise.

Nutrient quality

53 Moderate impact

Acetyl-L-carnitine reaches a useful amount, while tyrosine, choline, and most botanicals are too small for focused effects. Caffeine combined with bitter orange, hordenine, and yohimbine creates a safety trade-off without adding reliable dose depth.

.

Ingredient transparency

74 High impact

Active amounts are broadly clear and no proprietary blend hides the listed doses. Missing inactive ingredients and incomplete usage or source details prevent full label transparency.

.

Customer satisfaction

68 High impact

The average rating is strong and supported by a substantial review base. No specific feedback themes are supplied, so recurring stimulant complaints and purpose fit remain uncertain.

.

Value for money

56 Moderate impact

The serving cost is moderate and the acetyl-L-carnitine and caffeine amounts provide some concrete value. A crowded list of weak extras and an aggressive stimulant mix reduce quality-adjusted value.

.
Report analysis

Goals

Energy
Energy
Impact
High effect
A- Goal FitB Strength of SupportB CoverageF Formula Quality
Acetyl L-Carnitine · 500 mgCaffeine · 80 mg

Caffeine provides a clear acute alertness effect, while acetyl-L-carnitine and tyrosine add metabolic and focus support. The amounts are disclosed individually, which makes the main contributions assessable.

Many additional fat-burning botanicals have weaker or more uncertain energy relevance. Combining caffeine with bitter orange, hordenine, and yohimbine may increase jitteriness, heart rate, or blood pressure in sensitive users.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Caffeine Supportive 68 studies
Metabolism Boost
Metabolism Boost
Impact
High effect
B Goal FitB- Strength of SupportB- CoverageC Formula Quality
Acetyl L-Carnitine · 500 mgGreen Tea · 50 mgCaffeine · 80 mg

Caffeine, acetyl L-carnitine, bitter orange, cayenne, and green tea directly target energy and thermogenesis. Acetyl L-carnitine and caffeine are useful, while several botanicals lack strong active-marker disclosure.

The crowded stimulant combination includes yohimbine, hordenine, and bitter orange alongside caffeine. That overlap may raise heart rate, blood pressure, jitteriness, or sleep disruption in sensitive users.

Study evidence
Acetyl L-Carnitine Adverse 1 study
Caffeine Disputed 40 studies
Green Tea Supportive 31 studies
Mental Focus
Mental Focus
Impact
High effect
B- Goal FitB Strength of SupportB- CoverageC- Formula Quality
Choline · 20 mgAcetyl L-Carnitine · 500 mgCaffeine · 80 mg

Acetyl-L-carnitine, caffeine, and tyrosine provide mitochondrial, alertness, and catecholamine support for focus. Caffeine is clearly stated and acetyl-L-carnitine reaches a useful entry dose.

Tyrosine is low, while yohimbine, bitter orange, hordenine, and multiple caffeinated extracts create a complex stimulant load without theanine. The stack may increase jitteriness, heart rate, or blood pressure and is poorly suited to stimulant-sensitive users.

Study evidence
Acetyl L-Carnitine Supportive 7 studies
Caffeine Supportive 128 studies
Cognitive Support
Cognitive Support
Impact
High effect
B Goal FitC+ Strength of SupportB- CoverageC Formula Quality
Choline · 20 mgGreen Tea · 50 mgAcetyl L-Carnitine · 500 mg

The fat-burner contains a credible cognitive-energy stack despite its weight-management focus. Acetyl-L-carnitine, caffeine, tyrosine, and choline target mitochondrial energy, alertness, and neurotransmitter production.

Choline and tyrosine are modest, and the wider formula is not designed around memory outcomes. The core actives may support mental energy more than comprehensive cognition.

Study evidence
Acetyl L-Carnitine Supportive 20 studies
Choline Supportive 76 studies
Brain Health
Brain Health
Impact
High effect
B Goal FitC Strength of SupportC+ CoverageC- Formula Quality

Acetyl-L-carnitine supports brain energy, while tyrosine and caffeine may help alertness during short-term demand. The formula is designed primarily as a stimulant fat burner, so its brain-health value is secondary.

Acetyl-L-carnitine reaches a useful amount, but tyrosine and choline are too low for strong targeted support. Caffeine combined with yohimbine and hordenine may increase jitteriness, heart rate, or sleep disruption in stimulant-sensitive users.

Study evidence
Acetyl L-Carnitine Supportive 19 studies
Tyrosine Supportive 7 studies
Productivity Boost
Productivity Boost
Impact
High effect
B Goal FitB- Strength of SupportB- CoverageD- Formula Quality
Acetyl L-Carnitine · 500 mgAcetyl L-Carnitine · 500 mgCaffeine · 80 mg

Caffeine, acetyl-L-carnitine, and tyrosine directly address alertness, cellular energy, and neurotransmitter supply. Caffeine and acetyl-L-carnitine reach practical amounts, while tyrosine is far below the stronger productivity target.

Yohimbine, bitter orange, hordenine, green tea, and green coffee create a complex stimulant load without a calming counterbalance. That combination may increase jitteriness, heart rate, or sleep disruption, making the formula a less coherent productivity choice for stimulant-sensitive users.

Study evidence
Acetyl L-Carnitine Supportive 1 study
Acetyl L-Carnitine Supportive 1 study
Caffeine Supportive 108 studies

Ingredients

IngredientAmount per serving
Choline (Choline Bitartrate)
 20 mg
Acetyl-L-Carnitine HCl
500 mg
L-Tyrosine
200 mg
Advantra-Z Bitter Orange fruit extract
100 mg
Raspberry Ketone
100 mg
Garcinia fruit extract
100 mg
Caffeine Anhydrous
80 mg
Ginger root powder
70 mg
Green Tea leaf extract
50 mg
Green Coffee bean extract
50 mg
Hesperidin HCL
20 mg
Forskohlii root extract
20 mg
Capsimax Cayenne Pepper fruit extract
10 mg
Hordenine HCl
10 mg
Yohimbine (Yohimbe bark extract)
 2 mg
Adults 18–50 Women
Report overview
Acetyl L-Carnitine · 500 mg OverallScore85
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyD+ Value

Acetyl-L-carnitine HCl provides a clearly labeled 500 mg dose in the useful daily range. Cost efficiency is moderate for acetyl L-carnitine, and the salt form is well specified despite missing purity-testing details. Caffeine combined with yohimbine and hordenine may increase jitteriness or heart rate, making the formula unsuitable for some stimulant-sensitive users.

View ingredientView products
Choline (Choline Bitartrate) · 20 mg OverallScore52
C+ Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Choline bitartrate is a standard systemic source rather than a premium brain-targeted form. The 20 mg elemental amount is too low for strong standalone impact. A two-unit serving is manageable, although choline-specific value remains weak.

View ingredientView products
Tyrosine · 200 mg OverallScore50
B- Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

The preferred L-Tyrosine form is present, but the 200 mg dose is unlikely to offer strong acute cognitive support. Its amount is fully disclosed, while ingredient-specific purity and sourcing remain undocumented. The broader multi-ingredient formula delivers poor value when judged by tyrosine alone.

View ingredientView products
Loading alternative details
70 Performance

MotilPro

Pure Encapsulations
<p>A high ginger amount, acetyl-L-carnitine, active vitamin B6, and 5-HTP provide stronger digestive and cognitive alignment than the original token ginger and choline. Ginger may increase bleeding risk with anticoagulants, while 5-HTP can interact with serotonin-raising medicines.</p>
76 Performance

Multi for Women 55+

MegaFood
<p>Methylfolate, methylcobalamin, active vitamin B6, choline, green tea, vitamin D3, and chelated minerals provide broad support without a dense stimulant stack. The age and sex positioning may not fit every user, and repeated nutrient entries create some dose ambiguity.</p>
67 Performance

Trans4orm

Evlution Nutrition
<p>Caffeine and a much larger green tea amount provide stronger energy, weight-management, and metabolism alignment than the original formula. Yohimbe and incompletely specified huperzine add avoidable safety uncertainty, while several cognitive ingredients remain too small.</p>
61 Budget

Combat Cravings

OLLY
<p>A lower serving cost provides green tea and ginger in a simpler craving-support formula. Chromium is unusually concentrated and the botanical amounts are small, making routine unsupervised use difficult to justify.</p>
50 Budget

NoPhedra

Absolute Nutrition
<p>A lower serving cost keeps green tea and tyrosine in an alertness-focused blend. Unclear caffeine and synephrine yields plus combined green tea, guarana, and bitter orange create stimulant and blood-pressure uncertainty.</p>
74 Budget

D-Flame

NOW
<p>A lower serving cost provides clearly listed green tea, ginger, and other botanical extracts without the original product's long stack of overlapping stimulants. Some active amounts are modest or incompletely specified, so the formula is better suited to users prioritizing a gentler botanical profile.</p>
70 Value

LEANMODE

Evlution Nutrition
<p>Acetyl-L-carnitine plus large green tea and coffee extracts retain the original formula's main metabolic ingredients at a lower serving cost. Missing stimulant and extract yields make potency uncertain, while CLA and garcinia add limited value.</p>
76 Value

Multi for Men 55+

MegaFood
<p>Choline, green tea, active B vitamins, vitamin D3, natural vitamin E, and chelated minerals broaden general and cognitive support without overlapping stimulants. It costs somewhat more per serving and is age- and sex-specific, but the nutrient base is more balanced.</p>
68 Value

D-Flame

Protocol For Life Balance
<p>Green tea, ginger, and a broad botanical blend provide a non-stimulant-heavy route to some of the same ingredient collections. Several extracts are modest or incompletely specified, so the reasonable serving cost is balanced by only moderate formula focus.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of green tea on glucose control and insulin sensitivity: a meta-analysis of 17 randomized controlled trials.
    Liu K; Zhou R; Wang B; Chen K; Shi LY; Zhu JD; Mi MT · The American journal of clinical nutrition · 2013
    Meta-analysis1,133 participants17 studies pooledMetabolism Boost forGreen Tea
  2. Does supplementation of choline during or after pregnancies exposed to alcohol improve neurocognitive development of children? A meta-analysis.
    Lino GM; de Carvalho IN; de Amorim VOA; Bresani-Salvi CC; Luna VLM; Galvão PVM; Conrado GAM · Pediatrics and neonatology · 2025
    Meta-analysis5 studies pooledCognitive Support forCholine
  3. Metabolomic biomarkers for (R, S)-ketamine and (S)-ketamine in treatment-resistant depression and healthy controls: A systematic review.
    Kumar R; Nuñez NA; Joshi N; Joseph B; Verde A; Seshadri A; Cuellar Barboza AB; Prokop LJ; Medeiros GC; Singh B · Bipolar disorders · 2024
    Systematic reviewEnergy forAcetyl L-Carnitine
  4. Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults.
    Maki KC; Reeves MS; Farmer M; Yasunaga K; Matsuo N; Katsuragi Y; Komikado M; Tokimitsu I; Wilder D; Jones F; Blumberg JB; Cartwright Y · The Journal of nutrition · 2009
    Randomized trial132 participantsWeight Loss forGreen Tea
  5. The effect of ginger powder supplementation on insulin resistance and glycemic indices in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
    Mozaffari-Khosravi H; Talaei B; Jalali BA; Najarzadeh A; Mozayan MR · Complementary therapies in medicine · 2014
    Randomized trial88 participantsMetabolism Boost forGinger
  6. The effects of green tea extract supplementation on body composition, obesity-related hormones and oxidative stress markers: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials.
    Asbaghi O; Rezaei Kelishadi M; Larky DA; Bagheri R; Amirani N; Goudarzi K; Kargar F; Ghanavati M; Zamani M · The British journal of nutrition · 2024
    Meta-analysis3,802 participants59 studies pooledWeight Loss forGreen Tea
  7. Association of trimethylamine oxide and its precursors with cognitive impairment: a systematic review and meta-analysis.
    Long C; Li Z; Feng H; Jiang Y; Pu Y; Tao J; Yue R · Frontiers in aging neuroscience · 2024
    Meta-analysis82,246 participants9 studies pooledCognitive Support forCholine
  8. Effects of green tea or green tea extract on insulin sensitivity and glycaemic control in populations at risk of type 2 diabetes mellitus: a systematic review and meta-analysis of randomised controlled trials.
    Wang X; Tian J; Jiang J; Li L; Ying X; Tian H; Nie M · Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2015
    Meta-analysis510 participants7 studies pooledMetabolism Boost forGreen Tea
  9. Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients.
    Rossini M; Di Munno O; Valentini G; Bianchi G; Biasi G; Cacace E; Malesci D; La Montagna G; Viapiana O; Adami S · Clinical and experimental rheumatology · 2007
    Randomized trial102 participantsEnergy forAcetyl L-Carnitine
  10. The effect of zingiber officinale on prooxidant-antioxidant balance and glycemic control in diabetic patients with ESRD undergoing hemodialysis: a double-blind randomized control trial.
    Rostamkhani H; Veisi P; Niknafs B; Jafarabadi MA; Ghoreishi Z · BMC complementary medicine and therapies · 2023
    Randomized trialMetabolism Boost forGinger
  11. Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
    Malaguarnera G; Catania VE; Bertino G; Chisari LM; Castorina M; Bonfiglio C; Cauli O; Malaguarnera M · Current pharmaceutical design · 2022
    Randomized trial92 participantsAnti-Aging forAcetyl L-Carnitine
  12. Green tea and coffee intake and risk of cognitive decline in older adults: the National Institute for Longevity Sciences, Longitudinal Study of Aging.
    Shirai Y; Kuriki K; Otsuka R; Kato Y; Nishita Y; Tange C; Tomida M; Imai T; Ando F; Shimokata H · Public health nutrition · 2021
    Cohort study1,305 participantsAnti-Aging forGreen Tea
  13. Associations of green tea, coffee, and soft drink consumption with longitudinal changes in leukocyte telomere length.
    Sohn I; Shin C; Baik I · Scientific reports · 2023
    Cohort study1,952 participantsAnti-Aging forGreen Tea
  14. Can teatime increase one's lifetime?
    Nakachi K; Eguchi H; Imai K · Ageing research reviews · 2003
    Cohort studyAnti-Aging forGreen Tea
  15. Influences of tea consumption on self-rated health and life satisfaction among older adults: Evidence from the CLHLS.
    Zou M; Sun C; Yang M; Li C; Wang S; Zheng D; Wang J; Yu L; Sun L; Wang Y; Chen H; Zeng Y · PsyCh journal · 2025
    Cohort study78,345 participantsAnti-Aging forGreen Tea
  16. Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin.
    Chiu AE; Chan JL; Kern DG; Kohler S; Rehmus WE; Kimball AB · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial40 participantsAnti-Aging forGreen Tea
  17. Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
    Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
    Randomized trial125 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  18. Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
    Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
    Randomized trial130 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  19. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
    Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
    Randomized trialBrain Health forAcetyl L-Carnitine
  20. Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
    Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
    Randomized trial61 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  21. Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
    Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
    Randomized trial60 participantsBrain Health Mental Focus forAcetyl L-Carnitine
  22. Combined L-carnosine and L-tyrosine supplementation as an ergogenic strategy for physical and cognitive performance under fatigue in professional football players.
    Bilgin S; Bozyılan E; Buzdağlı Y; Karaç Öcal Y; Gürkan O; Toktaş S; İnan H; Egil İ; Yarayan YE · Frontiers in nutrition · 2026
    Randomized trial24 participantsBrain Health forTyrosine
  23. Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review.
    Jongkees BJ; Hommel B; Kühn S; Colzato LS · Journal of psychiatric research · 2016
    Narrative reviewBrain Health forTyrosine
  24. Influence of nutritional tyrosine on cognition and functional connectivity in healthy old humans.
    Hensel C; Becker M; Düzel S; Demuth I; Norman K; Steinhagen-Thiessen E; Gallinat J; Lindenberger U; Kühn S · NeuroImage · 2019
    Cross-sectional study286 participantsBrain Health forTyrosine
  25. Dietary Tyrosine Intake (FFQ) Is Associated with Locus Coeruleus, Attention and Grey Matter Maintenance: An MRI Structural Study on 398 Healthy Individuals of the Berlin Aging Study-II.
    Plini ERG; Melnychuk MC; Harkin A; Dahl MJ; McAuslan M; Kühn S; Boyle RT; Whelan R; Andrews R; Düzel S; Drewelies J; Wagner GG; Lindenberger U; Norman K; Robertson IH; Dockree PM · The journal of nutrition, health & aging · 2023
    Cross-sectional study398 participantsBrain Health forTyrosine
  26. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating.
    Jongkees BJ · Cognitive, affective & behavioral neuroscience · 2021
    Randomized trial45 participantsBrain Health forTyrosine
  27. A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
    Torrioli MG; Vernacotola S; Peruzzi L; Tabolacci E; Mila M; Militerni R; Musumeci S; Ramos FJ; Frontera M; Sorge G; Marzullo E; Romeo G; Vallee L; Veneselli E; Cocchi E; Garbarino E; Moscato U; Chiurazzi P; D'Iddio S; Calvani M; Neri G · American journal of medical genetics. Part A · 2008
    Randomized trial63 participantsCognitive Support forAcetyl L-Carnitine
  28. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.
    Malaguarnera M; Gargante MP; Cristaldi E; Colonna V; Messano M; Koverech A; Neri S; Vacante M; Cammalleri L; Motta M · Archives of gerontology and geriatrics · 2008
    Randomized trial96 participantsCognitive Support forAcetyl L-Carnitine
  29. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsCognitive Support forCholine
  30. Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study.
    Niu YY; Yan HY; Zhong JF; Diao ZQ; Li J; Li CP; Chen LH; Huang WQ; Xu M; Xu ZT; Liang XF; Li ZH; Liu D · The American journal of clinical nutrition · 2025
    Cohort study125,594 participantsCognitive Support forCholine
  31. Choline intake during pregnancy and child cognition at age 7 years.
    Boeke CE; Gillman MW; Hughes MD; Rifas-Shiman SL; Villamor E; Oken E · American journal of epidemiology · 2013
    Cohort study895 participantsCognitive Support forCholine
  32. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsCognitive Support forCholine
  33. Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes.
    Warton FL; Molteno CD; Warton CMR; Wintermark P; Lindinger NM; Dodge NC; Zöllei L; van der Kouwe AJW; Carter RC; Jacobson JL; Jacobson SW; Meintjes EM · Alcoholism, clinical and experimental research · 2022
    Randomized trial52 participantsCognitive Support forCholine
  34. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
    Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
    Randomized trial121 participantsEnergy forAcetyl L-Carnitine
  35. The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin.
    Malaguarnera M; Vacante M; Bertino G; Neri S; Malaguarnera M; Gargante MP; Motta M; Lupo L; Chisari G; Bruno CM; Pennisi G; Bella R · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2012
    Randomized trial60 participantsEnergy forAcetyl L-Carnitine
  36. Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy.
    Malaguarnera M; Bella R; Vacante M; Giordano M; Malaguarnera G; Gargante MP; Motta M; Mistretta A; Rampello L; Pennisi G · Scandinavian journal of gastroenterology · 2011
    Randomized trial67 participantsEnergy forAcetyl L-Carnitine
  37. A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy.
    Sun Y; Shu Y; Liu B; Liu P; Wu C; Zheng R; Zhang X; Zhuang Z; Deng Y; Zheng L; Xu Q; Jiang B; Ouyang X; Gao J; Xu N; Li X; Jiang S; Liang C; Yao Y · Experimental and therapeutic medicine · 2020
    Randomized trial239 participantsEnergy forAcetyl L-Carnitine
  38. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine.
    Haskell CF; Kennedy DO; Wesnes KA; Scholey AB · Psychopharmacology · 2005
    Randomized trial48 participantsEnergy forCaffeine
  39. Caffeine-containing energy drink improves physical performance of elite rugby players during a simulated match.
    Del Coso J; Ramírez JA; Muñoz G; Portillo J; Gonzalez-Millán C; Muñoz V; Barbero-Álvarez JC; Muñoz-Guerra J · Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2016
    Randomized trial26 participantsEnergy forCaffeine
  40. Differential cognitive effects of energy drink ingredients: caffeine, taurine, and glucose.
    Giles GE; Mahoney CR; Brunyé TT; Gardony AL; Taylor HA; Kanarek RB · Pharmacology, biochemistry, and behavior · 2013
    Randomized trial48 participantsEnergy forCaffeine
  41. Does Single or Combined Caffeine and Taurine Supplementation Improve Athletic and Cognitive Performance without Affecting Fatigue Level in Elite Boxers? A Double-Blind, Placebo-Controlled Study.
    Ozan M; Buzdagli Y; Eyipinar CD; Baygutalp NK; Yüce N; Oget F; Kan E; Baygutalp F · Nutrients · 2022
    Randomized trial20 participantsEnergy forCaffeine
  42. Trait Energy and Fatigue Modify the Effects of Caffeine on Mood, Cognitive and Fine-Motor Task Performance: A Post-Hoc Study.
    Fuller DT; Smith ML; Boolani A · Nutrients · 2021
    Randomized trialEnergy forCaffeine
  43. Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial.
    Malaguarnera G; Pennisi M; Gagliano C; Vacante M; Malaguarnera M; Salomone S; Drago F; Bertino G; Caraci F; Nunnari G; Malaguarnera M · Hepatitis monthly · 2014
    Randomized trial62 participantsMental Focus Productivity Boost forAcetyl L-Carnitine
  44. [Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration].
    Lino A; Boccia MM; Rusconi AC; Bellomonte L; Cocuroccia B · La Clinica terapeutica · 1992
    Non-randomized trial17 participantsMental Focus forAcetyl L-Carnitine
  45. Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial.
    Arnold LE; Amato A; Bozzolo H; Hollway J; Cook A; Ramadan Y; Crowl L; Zhang D; Thompson S; Testa G; Kliewer V; Wigal T; McBurnett K; Manos M · Journal of child and adolescent psychopharmacology · 2008
    Randomized trial112 participantsMental Focus forAcetyl L-Carnitine
  46. Acetyl-L-carnitine for patients with hepatic encephalopathy.
    Martí-Carvajal AJ; Gluud C; Arevalo-Rodriguez I; Martí-Amarista CE · The Cochrane database of systematic reviews · 2019
    Meta-analysis398 participants5 studies pooledMental Focus forAcetyl L-Carnitine
  47. Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.
    Wingelaar-Jagt YQ; Bottenheft C; Riedel WJ; Ramaekers JG · Journal of psychopharmacology (Oxford, England) · 2023
    Randomized trial32 participantsMental Focus forCaffeine
  48. Acute effects of caffeine on attention: a comparison of non-consumers and withdrawn consumers.
    Smith AP; Christopher G; Sutherland D · Journal of psychopharmacology (Oxford, England) · 2013
    Randomized trial70 participantsMental Focus forCaffeine
  49. Performance and alertness effects of caffeine, dextroamphetamine, and modafinil during sleep deprivation.
    Wesensten NJ; Killgore WD; Balkin TJ · Journal of sleep research · 2006
    Randomized trial48 participantsMental Focus forCaffeine
  50. Effects of caffeine on mood and performance: a study of realistic consumption.
    Brice CF; Smith AP · Psychopharmacology · 2003
    Clinical trial24 participantsMental Focus forCaffeine
  51. Effects of caffeine or diphenhydramine on visual vigilance.
    Fine BJ; Kobrick JL; Lieberman HR; Marlowe B; Riley RH; Tharion WJ · Psychopharmacology · 1995
    Randomized trial24 participantsMental Focus forCaffeine
  52. Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.
    Krims-Davis K; Ozola M; Razzivina V; Gukalova B; Konrade I; Dambrova M; Liepinsh E · Molecular nutrition & food research · 2025
    Randomized trialMetabolism Boost forAcetyl L-Carnitine
  53. A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.
    Krieger J; Schrautemeier A; Hagele A; Gaige C; Mennemeyer O; Tolbert S; Iannotti J; Kerksick C; Noonan C; Mumford P · Nutrients · 2025
    Randomized trial60 participantsMetabolism Boost forCaffeine
  54. Oolong tea increases metabolic rate and fat oxidation in men.
    Rumpler W; Seale J; Clevidence B; Judd J; Wiley E; Yamamoto S; Komatsu T; Sawaki T; Ishikura Y; Hosoda K · The Journal of nutrition · 2001
    Randomized trial12 participantsMetabolism Boost forCaffeine
  55. Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?
    Gutiérrez-Hellín J; Aguilar-Navarro M; Ruiz-Moreno C; Muñoz A; Varillas-Delgado D; Amaro-Gahete FJ; Del Coso J · European journal of nutrition · 2023
    Randomized trial18 participantsMetabolism Boost forCaffeine
  56. Comparison of changes in energy expenditure and body temperatures after caffeine consumption.
    Koot P; Deurenberg P · Annals of nutrition & metabolism · 1995
    Randomized trial12 participantsMetabolism Boost forCaffeine
  57. Caffeine Increases Work Done above Critical Power, but Not Anaerobic Work.
    Silveira R; Andrade-Souza VA; Arcoverde L; Tomazini F; Sansonio A; Bishop DJ; Bertuzzi R; Lima-Silva AE · Medicine and science in sports and exercise · 2018
    Randomized trial9 participantsMetabolism Boost forCaffeine
  58. Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans.
    Venables MC; Hulston CJ; Cox HR; Jeukendrup AE · The American journal of clinical nutrition · 2008
    Randomized trial23 participantsMetabolism Boost forGreen Tea
  59. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.
    Dulloo AG; Duret C; Rohrer D; Girardier L; Mensi N; Fathi M; Chantre P; Vandermander J · The American journal of clinical nutrition · 1999
    Randomized trial10 participantsMetabolism Boost forGreen Tea
  60. A 60-Day Green Tea Extract Supplementation Counteracts the Dysfunction of Adipose Tissue in Overweight Post-Menopausal and Class I Obese Women.
    Rondanelli M; Gasparri C; Perna S; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Cavioni A; Mansueto F; Oberto L; Patelli Z; Tartara A; Riva A · Nutrients · 2022
    Randomized trial28 participantsMetabolism Boost forGreen Tea
  61. Epigallocatechin gallate alleviates non-alcoholic fatty liver disease through the inhibition of the expression and activity of Dipeptide kinase 4.
    Yang M; Yan R; Sha R; Wang X; Zhou S; Li B; Zheng Q; Cao Y · Clinical nutrition (Edinburgh, Scotland) · 2024
    Randomized trialMetabolism Boost forGreen Tea
  62. Effects of caffeine on alertness.
    Zwyghuizen-Doorenbos A; Roehrs TA; Lipschutz L; Timms V; Roth T · Psychopharmacology · 1990
    Randomized trial24 participantsProductivity Boost forCaffeine
  63. Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance.
    Irwin C; McCartney D; Grant G; Delang N; Bartrim K; Cox GR; Desbrow B · Perceptual and motor skills · 2023
    Randomized trial22 participantsProductivity Boost forCaffeine
  64. Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.
    Lieberman HR; Tharion WJ; Shukitt-Hale B; Speckman KL; Tulley R · Psychopharmacology · 2003
    Randomized trial68 participantsProductivity Boost forCaffeine
  65. A review of caffeine's effects on cognitive, physical and occupational performance.
    McLellan TM; Caldwell JA; Lieberman HR · Neuroscience and biobehavioral reviews · 2017
    Narrative reviewProductivity Boost forCaffeine
  66. Acute caffeine supplementation as a nutrition-based strategy to mitigate sleep-loss-related cognitive and operational performance impairments in military personnel: a systematic review and meta-analysis.
    Wang R; Wang W; Meng L; Hao G; Gu G · Frontiers in nutrition · 2026
    Meta-analysis7 studies pooledProductivity Boost forCaffeine
  67. Changes in caffeine intake and long-term weight change in men and women.
    Lopez-Garcia E; van Dam RM; Rajpathak S; Willett WC; Manson JE; Hu FB · The American journal of clinical nutrition · 2006
    Cohort study58,157 participantsWeight Loss forCaffeine
  68. Does caffeine ingestion before a short-term sprint interval training promote body fat loss?
    Ferreira GA; Felippe LC; Bertuzzi R; Bishop DJ; Ramos IS; De-Oliveira FR; Lima-Silva AE · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2020
    Randomized trial20 participantsWeight Loss forCaffeine
  69. Eight Weeks of Sprint Interval Training With Adding Caffeine Ingestion Leads to Greater Improvements in Health-Related Physiological Parameters in Obese Male Adults.
    Zhiang J; Song Q · Physiological research · 2026
    Randomized trial30 participantsWeight Loss forCaffeine
  70. Caffeine treatment prevented from weight regain after calorie shifting diet induced weight loss.
    Davoodi SH; Hajimiresmaiel SJ; Ajami M; Mohseni-Bandpei A; Ayatollahi SA; Dowlatshahi K; Javedan G; Pazoki-Toroudi H · Iranian journal of pharmaceutical research : IJPR · 2014
    Non-randomized trial60 participantsWeight Loss forCaffeine
  71. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials.
    Tabrizi R; Saneei P; Lankarani KB; Akbari M; Kolahdooz F; Esmaillzadeh A; Nadi-Ravandi S; Mazoochi M; Asemi Z · Critical reviews in food science and nutrition · 2020
    Meta-analysis606 participants13 studies pooledWeight Loss forCaffeine
  72. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans.
    Nagao T; Hase T; Tokimitsu I · Obesity (Silver Spring, Md.) · 2007
    Randomized trial240 participantsWeight Loss forGreen Tea
  73. Green tea beverages enriched with catechins with a galloyl moiety reduce body fat in moderately obese adults: a randomized double-blind placebo-controlled trial.
    Kobayashi M; Kawano T; Ukawa Y; Sagesaka YM; Fukuhara I · Food & function · 2016
    Randomized trial126 participantsWeight Loss forGreen Tea
  74. Effect of Decaffeinated Green Tea Polyphenols on Body Fat and Precocious Puberty in Obese Girls: A Randomized Controlled Trial.
    Xie L; Tang Q; Yao D; Gu Q; Zheng H; Wang X; Yu Z; Shen X · Frontiers in endocrinology · 2022
    Randomized trial62 participantsWeight Loss forGreen Tea
  75. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial.
    Auvichayapat P; Prapochanung M; Tunkamnerdthai O; Sripanidkulchai BO; Auvichayapat N; Thinkhamrop B; Kunhasura S; Wongpratoom S; Sinawat S; Hongprapas P · Physiology & behavior · 2008
    Randomized trial60 participantsWeight Loss forGreen Tea