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Optimized Chromium with Crominex 3+ 500 mcg

Life Extension
4.7
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(6733 ratings)
Chromium 500 mcg
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Score86
Crominex 3+ chromium offers focused support for glucose metabolism, not a direct metabolic-rate increase. Weight-loss effects are likely to be small and inconsistent.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Metabolism Boost
Weight Loss

Score 86

Crominex 3+ chromium offers focused support for glucose metabolism, not a direct metabolic-rate increase. Weight-loss effects are likely to be small and inconsistent.
How scoring works
$6.75($0.11 per serving)
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$ 6.75
Pure Formulas
$ 6.75
Amazon
$ 6.75
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$ 6.75
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Analysis

The capsule supplies 500 mcg chromium as Crominex 3+ chromium, a clearly identified source aimed at normal insulin action and carbohydrate handling. Its practical benefit is most plausible when chromium intake or glucose regulation is suboptimal.

Chromium does not reliably create satiety, thermogenesis, or meaningful weight loss on its own. The single-active design gives one pathway good depth but leaves appetite, protein intake, muscle preservation, and energy expenditure unaddressed.

The amount is within a common targeted supplemental range and the simple label supports informed use. The named branded source improves form confidence. People using glucose-lowering medicine need to consider additive effects.

Who is it for
  • Adults with a defined reason for chromium supplementation
  • Users seeking a stimulant-free single-mineral product
  • People who prefer a capsule
Best for
  • Targeted chromium intake
  • Supporting normal carbohydrate metabolism
  • Users avoiding multi-ingredient blends

Pros

  • Uses Crominex 3+ chromium
  • Chromium amount is clearly listed
  • Simple formula is easy to assess
  • Stimulant-free design

Cons

  • Does not directly raise metabolic rate
  • Unlikely to produce meaningful weight loss alone
  • Covers only one metabolic pathway
  • Benefit may be limited when chromium status is adequate

Warnings

  • Chromium may add to the effects of insulin or sulfonylurea medicines and contribute to low blood sugar
  • Take chromium separately from levothyroxine because it may reduce thyroid-medicine absorption
  • Avoid stacking with another chromium supplement without checking the combined amount

Nutrient quality

95 Highest impact

A branded source and targeted amount provide strong chromium quality. The narrow product does not support thermogenesis or satiety.

Ingredient transparency

81 Highest impact

The branded chromium source and amount are visible. Elemental-yield detail, complete directions, and inactive ingredients remain incomplete.

Customer satisfaction

71 High impact

The aggregate rating is strong and the evidence base is very large. Specific experience details are unavailable, so complaint patterns and purpose fit remain uncertain.

Value for money

98 Highest impact

Branded quality and low recurring cost create excellent value. Narrow pathway coverage is the main limitation.

Report analysis

Goals

Metabolism Boost
Impact
Highest effect
B Goal FitA Strength of SupportC- CoverageA+ Formula Quality

Chromium may support insulin action and carbohydrate handling, particularly when glucose regulation is impaired. It is not a direct thermogenic stimulant and does not reliably raise metabolic rate in healthy users.

The branded chromium complex provides a well-targeted, clearly disclosed amount. People using glucose-lowering medicine should monitor for additive blood-sugar effects.

Study evidence
Chromium Supportive 47 studies
Weight Loss
Impact
High effect
D- Goal FitA- Strength of SupportD+ CoverageA- Formula Quality

Chromium may support glucose control and cravings in people with impaired insulin sensitivity. Expected effects on body weight are modest and inconsistent for the general population.

The branded chromium form and fully stated 500 mcg amount provide excellent transparency. A single-ingredient design is focused, but it covers only one indirect pathway.

Study evidence
Chromium No effect 24 studies

Ingredients

IngredientAmount per serving
Chromium (Crominex 3+ Chromium)
500 mcg
Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

Crominex 3+ provides a recognized branded chromium source at a well-targeted 500 mcg amount. The dose is economical and sits at the upper end of the preferred range. Label data still present only one chromium amount rather than separating elemental and compound weights.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  2. A pilot study of chromium picolinate for weight loss.
    Yazaki Y; Faridi Z; Ma Y; Ali A; Northrup V; Njike VY; Liberti L; Katz DL · Journal of alternative and complementary medicine (New York, N.Y.) · 2010
    Randomized trial80 participantsWeight Loss forChromium
  3. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  4. Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.
    Kooshki F; Moradi F; Karimi A; Niazkar HR; Khoshbaten M; Maleki V; Pourghassem Gargari B · European journal of gastroenterology & hepatology · 2021
    Randomized trial46 participantsWeight Loss forChromium
  5. The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Heshmati J; Omani-Samani R; Vesali S; Maroufizadeh S; Rezaeinejad M; Razavi M; Sepidarkish M · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2018
    Meta-analysis268 participants5 studies pooledMetabolism Boost forChromium
  6. Association Between Essential and Non-essential Metals, Body Composition, and Metabolic Syndrome in Adults.
    Ngu YJ; Skalny AV; Tinkov AA; Tsai CS; Chang CC; Chuang YK; Nikolenko VN; Zotkin DA; Chiu CF; Chang JS · Biological trace element research · 2022
    Cross-sectional study150 participantsWeight Loss forChromium
  7. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
    Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
    Randomized trial180 participantsMetabolism Boost forChromium
  8. The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease.
    Farrokhian A; Mahmoodian M; Bahmani F; Amirani E; Shafabakhsh R; Asemi Z · Biological trace element research · 2021
    Randomized trial64 participantsWeight Loss forChromium
  9. Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.
    Ali A; Ma Y; Reynolds J; Wise JP; Inzucchi SE; Katz DL · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2011
    Randomized trial59 participantsMetabolism Boost forChromium
  10. Chromium picolinate supplementation in women: effects on body weight, composition, and iron status.
    Lukaski HC; Siders WA; Penland JG · Nutrition (Burbank, Los Angeles County, Calif.) · 2007
    Randomized trial83 participantsWeight Loss forChromium
  11. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
    Martin J; Wang ZQ; Zhang XH; Wachtel D; Volaufova J; Matthews DE; Cefalu WT · Diabetes care · 2006
    Randomized trial37 participantsMetabolism Boost Weight Loss forChromium
  12. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forChromium
  13. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
    Ashoush S; Abou-Gamrah A; Bayoumy H; Othman N · The journal of obstetrics and gynaecology research · 2017
    Randomized trial100 participantsWeight Loss forChromium
  14. [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
    San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
    Meta-analysis13 studies pooledMetabolism Boost forChromium
  15. Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults.
    Iqbal N; Cardillo S; Volger S; Bloedon LT; Anderson RA; Boston R; Szapary PO · Metabolic syndrome and related disorders · 2009
    Randomized trial63 participantsMetabolism Boost Weight Loss forChromium
  16. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
    Suksomboon N; Poolsup N; Yuwanakorn A · Journal of clinical pharmacy and therapeutics · 2015
    Meta-analysis25 studies pooledMetabolism Boost forChromium
  17. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry.
    Guimarães MM; Carvalho AC; Silva MS · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2017
    Randomized trial56 participantsWeight Loss forChromium
  18. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial.
    Kleefstra N; Houweling ST; Jansman FG; Groenier KH; Gans RO; Meyboom-de Jong B; Bakker SJ; Bilo HJ · Diabetes care · 2006
    Randomized trial46 participantsWeight Loss forChromium
  19. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
    Randomized trial64 participantsMetabolism Boost forChromium
  20. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
    Systematic review33 studies pooledMetabolism Boost forChromium
  21. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
    Fazelian S; Rouhani MH; Bank SS; Amani R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2018
    Meta-analysis351 participants7 studies pooledWeight Loss forChromium