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Blood Sugar Support

Vital Nutrients
4.8
★ ★ ★ ★ ★
(79 ratings)
Chromium 500 mcg
Vanadium 250 mcg
Fenugreek 400 mg
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Score66
A strong glucose-management blend combines chromium, vanadium, and several botanicals. Low-blood-sugar interactions, weak botanical standardization, and high biotin are important trade-offs.
How scoring works
Quantity:60 Capsule(s) • (30 servings)
Goals:
Metabolism Boost
Weight Loss

Score 66

A strong glucose-management blend combines chromium, vanadium, and several botanicals. Low-blood-sugar interactions, weak botanical standardization, and high biotin are important trade-offs.
How scoring works
$33.99($1.13 per serving)
Pure Formulas
$ 33.99
iHerb
$ 33.99
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Analysis

Chromium at 500 mcg and vanadium at 250 mcg provide substantial mineral support for glucose-related pathways. Holy basil and fenugreek each reach 400 mg, with ginseng, cinnamon, and gymnema adding breadth.

Most botanicals lack active-marker standardization, so potency is less certain than the listed weights suggest. Biotin reaches 4.5 mg, a high amount unrelated to most glucose goals.

The formula may fit users tracking carbohydrate handling with professional guidance. It is not a direct fat-loss product, and combining several glucose-lowering agents requires careful monitoring.

Who is it for
  • Adults seeking glucose-metabolism support
  • Users who can monitor blood sugar
  • People comfortable with multi-botanical capsules
Best for
  • Carbohydrate-handling support
  • Chromium and vanadium coverage
  • Broad metabolic botanical support

Pros

  • Uses chromium polynicotinate
  • Meaningful holy basil and fenugreek amounts
  • Clearly discloses ingredient weights
  • Combines several complementary pathways

Cons

  • Botanical standardization is limited
  • High biotin is not central to the goal
  • Premium serving cost
  • Not a direct weight-loss formula

Warnings

  • Chromium, vanadium, fenugreek, gymnema, ginseng, and cinnamon may add to insulin or sulfonylurea effects and increase low-blood-sugar risk.
  • The 4.5 mg biotin amount can interfere with some laboratory tests; disclose use before blood work.
  • Fenugreek may cause gas, diarrhea, or maple-like body odor in sensitive users.

Nutrient quality

71 High impact

The ingredients align well with metabolic support and several amounts are meaningful. Incomplete extract standardization and additive glucose-lowering effects limit confidence and safety.

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Ingredient transparency

74 High impact

Individual active weights are disclosed without a hidden blend. Missing extract potency, full directions, and inactive ingredients prevent complete evaluation.

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Customer satisfaction

62 Moderate impact

The average customer rating is very strong. A modest rating base limits confidence in the average, while specific review experiences were not supplied.

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Value for money

52 Moderate impact

The broad metabolic formula offers several relevant actives. High serving cost and incomplete botanical potency make it weak value.

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Goals

Impact
Highest effect
A- Goal FitB+ Strength of SupportB+ CoverageA Formula Quality
Biotin · 4.5 mg

Chromium, fenugreek, holy basil, gymnema, cinnamon, ginseng, and vanadium create a strong glucose-control formula. The product is more focused on insulin sensitivity and carbohydrate handling than on thermogenesis, but that pathway is directly relevant to the selected goal.

Chromium is strongly dosed in a useful form, and several botanicals reach meaningful amounts. Chromium, vanadium, gymnema, and related ingredients may add to glucose-lowering medicines and increase the risk of low blood sugar.

Study evidence
Chromium Supportive 47 studies
Vanadium Supportive 7 studies
Weight Loss
Impact
High effect
C Goal FitB- Strength of SupportC+ CoverageA- Formula Quality

Chromium, fenugreek, gymnema, cinnamon, and other botanicals may support glucose regulation, which is only an indirect weight-management pathway. Human evidence for meaningful weight loss from the combination is mixed and less convincing than evidence for fiber, protein, or caffeine.

Chromium polynicotinate has a clear useful amount, while several botanicals also have disclosed totals. Missing active-marker standardization for the plant extracts limits potency assessment despite reasonable dosing. Gymnema, fenugreek, ginseng, chromium, and vanadium may add to glucose-lowering medicines and increase the risk of low blood sugar.

Study evidence
Chromium No effect 24 studies

Ingredients

IngredientAmount per serving
Biotin
4.5 mg
Chromium (Chromium Polynicotinate)
500 mcg
American Ginseng root extract
225 mg
Holy Basil leaf extract
400 mg
Fenugreek
400 mg
Gymnema sylvestre leaf extract
100 mg
Cinnamon
200 mg
Vanadium (Vanadium Citrate)
250 mcg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB Value

Chromium polynicotinate provides a well-absorbed organic source, though no trademarked supplier is identified. The 500 mcg amount fits the target range, but a single label value leaves elemental yield and compound weight ambiguous. Companion value from a substantial vanadium amount improves an otherwise moderate standardized chromium cost.

D- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

Vanadium citrate provides moderate form quality at the upper edge of the preferred 250 mcg range. Elemental labeling is clear, but the supplied information lacks manufacturing or independent testing signals. Vanadium at this dose may add to glucose-lowering medicines and increase low-blood-sugar risk.

Fenugreek · 400 mg OverallScore33
F Active Ingredient Quality & BioavailabilityD+ Dose, Safety & Label TransparencyF Value

Fenugreek is present at a modest amount, but the label does not identify it as a standardized extract or disclose active markers. The dry capsules include no absorption enhancer, and the amount is low for whole-seed use. A high serving cost further weakens its fit as a dedicated fenugreek option.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
    Suksomboon N; Poolsup N; Yuwanakorn A · Journal of clinical pharmacy and therapeutics · 2015
    Meta-analysis25 studies pooledMetabolism Boost forChromium
  2. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  3. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  4. Insulin Receptor Substrates Regulation and Clinical Responses Following Vanadium-Enriched Yeast Supplementation in Obese Type 2 Diabetic Patients: a Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Ghalichi F; Saghafi-Asl M; Kafil B; Faghfouri AH; Jourshari MR; Naserkiadeh AA; Ostadrahimi A · Biological trace element research · 2023
    Randomized trial44 participantsMetabolism Boost forVanadium
  5. Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance.
    Jacques-Camarena O; González-Ortiz M; Martínez-Abundis E; López-Madrueño JF; Medina-Santillán R · Annals of nutrition & metabolism · 2009
    Randomized trial14 participantsMetabolism Boost forVanadium
  6. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
    Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
    Randomized trial180 participantsMetabolism Boost forChromium
  7. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
    Randomized trial64 participantsMetabolism Boost forChromium
  8. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
    Systematic review33 studies pooledMetabolism Boost forChromium
  9. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forChromium
  10. [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
    San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
    Meta-analysis13 studies pooledMetabolism Boost forChromium
  11. Insulin signal mimicry as a mechanism for the insulin-like effects of vanadium.
    Mehdi MZ; Pandey SK; Théberge JF; Srivastava AK · Cell biochemistry and biophysics · 2006
    Narrative reviewMetabolism Boost forVanadium
  12. Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies.
    Goldfine AB; Patti ME; Zuberi L; Goldstein BJ; LeBlanc R; Landaker EJ; Jiang ZY; Willsky GR; Kahn CR · Metabolism: clinical and experimental · 2000
    Clinical trial16 participantsMetabolism Boost forVanadium
  13. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes.
    Cusi K; Cukier S; DeFronzo RA; Torres M; Puchulu FM; Redondo JC · The Journal of clinical endocrinology and metabolism · 2001
    Single-arm trial11 participantsMetabolism Boost forVanadium
  14. The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease.
    Farrokhian A; Mahmoodian M; Bahmani F; Amirani E; Shafabakhsh R; Asemi Z · Biological trace element research · 2021
    Randomized trial64 participantsWeight Loss forChromium
  15. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
    Martin J; Wang ZQ; Zhang XH; Wachtel D; Volaufova J; Matthews DE; Cefalu WT · Diabetes care · 2006
    Randomized trial37 participantsWeight Loss forChromium
  16. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
    Ashoush S; Abou-Gamrah A; Bayoumy H; Othman N · The journal of obstetrics and gynaecology research · 2017
    Randomized trial100 participantsWeight Loss forChromium
  17. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
    Fazelian S; Rouhani MH; Bank SS; Amani R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2018
    Meta-analysis351 participants7 studies pooledWeight Loss forChromium
  18. Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.
    Kooshki F; Moradi F; Karimi A; Niazkar HR; Khoshbaten M; Maleki V; Pourghassem Gargari B · European journal of gastroenterology & hepatology · 2021
    Randomized trial46 participantsWeight Loss forChromium