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Glycemic Factors

Country Life
4.6
★ ★ ★ ★ ★
(174 ratings)
Chromium 200 mcg
Copper 0.5 mg
Vanadium 781 mcg
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Score56
A low-cost chromium and high-vanadium formula whose opaque botanical blend and medication-related hypoglycemia risk are major trade-offs.
How scoring works
Quantity:100 Tablet(s) • (100 servings)
Goals:
Metabolism Boost

Score 56

A low-cost chromium and high-vanadium formula whose opaque botanical blend and medication-related hypoglycemia risk are major trade-offs.
How scoring works
$23.39($0.23 per serving)
iHerb
$ 23.39
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Analysis

Chromium picolinate is supplied at a useful targeted amount, while vanadyl sulfate provides a large vanadium contribution. B vitamins, magnesium, olive leaf, and other minerals add a wider metabolic context.

The botanical blend does not disclose its individual ingredients or amounts. That omission prevents a full assessment of the product's effectiveness and interactions despite clear mineral labeling.

One-tablet use and low cost are practical strengths. The high vanadium amount makes the product poorly suited to casual use alongside glucose-lowering medication.

Who is it for
  • Adults seeking targeted metabolic minerals
  • Users not taking glucose-lowering medicines
  • People who can monitor glucose response
Best for
  • Chromium-centered glycemic formulas
  • One-tablet metabolic support
  • Users who have reviewed the botanical blend

Pros

  • Useful chromium picolinate amount
  • Clear vanadium quantity
  • Low serving cost

Cons

  • Vanadium amount is high
  • Botanical blend is undisclosed
  • Copper amount is modest

Warnings

  • High supplemental vanadium may add to diabetes medicines and increase the risk of low blood sugar.
  • Review the current botanical blend before use because its contents are not supplied.

Nutrient quality

53 Moderate impact

Chromium picolinate is a useful form, but several vitamins use conventional forms and the botanical blend is unspecified. Chromium is meaningful and vanadium is high, while magnesium is modest and individual botanical doses are hidden, while the high vanadium amount may amplify glucose-lowering medicines, especially alongside chromium and other metabolic ingredients.

Ingredient transparency

41 Lower impact

Several minerals have exact amounts, but the Botanical Blend conceals its ingredients and doses. Serving totals are apparent, but full directions and inactive ingredients are not supplied.

Customer satisfaction

65 Moderate impact

The supplied average rating is favorable. A substantial rating base gives the average reasonable reliability, while complaint and firsthand experience details are unavailable.

Value for money

74 High impact

Formula quality provides partial support for the asking position. The serving value is reasonably competitive within the category.

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Goals

Metabolism Boost
Impact
High effect
B+ Goal FitC Strength of SupportC+ CoverageC Formula Quality
Vitamin B12 · 50 mcgVitamin B6 · 7.5 mgMagnesium · 50 mg

Chromium-led glycemic support gives the formula meaningful metabolic relevance. Opaque botanicals and low magnesium weaken its broader contribution.

It targets glucose handling more than calorie expenditure or fat oxidation. Chromium and vanadium may compound the effects of glucose-lowering medicines.

Study evidence
Chromium Supportive 47 studies
Magnesium Supportive 61 studies
Vanadium Supportive 7 studies

Ingredients

IngredientAmount per serving
Vitamin B6 (Pyridoxine Hydrochloride Alpha-Ketoglutarate)
7.5 mg
Folate
334 mcg DFE
Vitamin B12 (Cyanocobalamin)
50 mcg
Calcium (Calcium Carbonate)
60 mg
Magnesium (Magnesium Aspartate)
50 mg
Olive leaf extract (Oleuropein)
2.5 mg
Copper (Copper Lysinate Hydrochloride)
0.5 mg
Manganese (Manganese Citrate)
1.5 mg
Chromium (Chromium Picolinate)
200 mcg
Potassium (Potassium Aspartate)
49.5 mg
Botanical Blend
143.8 mg
Vanadium (Vanadyl Sulfate)
781 mcg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
B- Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyA+ Value

Chromium picolinate provides a well-absorbed organic source, though no trademarked supplier is identified. The 200 mcg amount fits the target range, but a single label value leaves elemental yield and compound weight ambiguous. Low standardized chromium cost and a substantial vanadium amount create especially strong metabolic-formula value.

A+ Active Ingredient Quality & BioavailabilityD- Dose, Safety & Label TransparencyB+ Value

Copper lysinate is an amino acid-bound form with strong absorption potential. The copper amount is below the adult daily requirement. The absence of zinc avoids direct competition but provides no built-in mineral balance. The serving cost is near or below the category median, supporting good value.

C- Active Ingredient Quality & BioavailabilityD Dose, Safety & Label TransparencyA+ Value

Vanadyl sulfate provides a commonly researched form, but the serving is in a high supplemental range. The label clearly states the vanadium amount, and the low cost per serving supports good value. The 781 mcg dose warrants professional guidance, especially for people using glucose-lowering medication because the formula also contains chromium and several metabolic-support ingredients.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Insulin Receptor Substrates Regulation and Clinical Responses Following Vanadium-Enriched Yeast Supplementation in Obese Type 2 Diabetic Patients: a Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Ghalichi F; Saghafi-Asl M; Kafil B; Faghfouri AH; Jourshari MR; Naserkiadeh AA; Ostadrahimi A · Biological trace element research · 2023
    Randomized trial44 participantsMetabolism Boost forVanadium
  2. Effect of vanadium on insulin sensitivity in patients with impaired glucose tolerance.
    Jacques-Camarena O; González-Ortiz M; Martínez-Abundis E; López-Madrueño JF; Medina-Santillán R · Annals of nutrition & metabolism · 2009
    Randomized trial14 participantsMetabolism Boost forVanadium
  3. Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies.
    Goldfine AB; Patti ME; Zuberi L; Goldstein BJ; LeBlanc R; Landaker EJ; Jiang ZY; Willsky GR; Kahn CR · Metabolism: clinical and experimental · 2000
    Clinical trial16 participantsMetabolism Boost forVanadium
  4. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus.
    Boden G; Chen X; Ruiz J; van Rossum GD; Turco S · Metabolism: clinical and experimental · 1996
    Non-randomized trial8 participantsMetabolism Boost forVanadium
  5. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
    Suksomboon N; Poolsup N; Yuwanakorn A · Journal of clinical pharmacy and therapeutics · 2015
    Meta-analysis25 studies pooledMetabolism Boost forChromium
  6. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  7. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
    Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
    Randomized trial180 participantsMetabolism Boost forChromium
  8. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  9. The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Heshmati J; Omani-Samani R; Vesali S; Maroufizadeh S; Rezaeinejad M; Razavi M; Sepidarkish M · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2018
    Meta-analysis268 participants5 studies pooledMetabolism Boost forChromium
  10. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
    Randomized trial64 participantsMetabolism Boost forChromium
  11. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
    Systematic review33 studies pooledMetabolism Boost forChromium
  12. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forChromium
  13. [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
    San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
    Meta-analysis13 studies pooledMetabolism Boost forChromium
  14. Association of magnesium consumption with type 2 diabetes and glucose metabolism: A systematic review and pooled study with trial sequential analysis.
    Zhao B; Deng H; Li B; Chen L; Zou F; Hu L; Wei Y; Zhang W · Diabetes/metabolism research and reviews · 2021
    Meta-analysis1,168 participants26 studies pooledMetabolism Boost forMagnesium
  15. Magnesium supplementation for glycemic status in women with gestational diabetes: a systematic review and meta-analysis.
    Tan X; Huang Y · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Meta-analysis4 studies pooledMetabolism Boost forMagnesium
  16. Impact of oral magnesium supplementation on glycemic and cardiometabolic outcomes in prediabetic adults: a systematic review and meta-analysis.
    Basit A; Kumar S; Ahmed H; Babar R; Saeed SS; Siddiqui TA; Khan S; Saeed A; Khan M; Hanif H; Fasih A; Shabbir S; Kumar H; Kumar L; Raja A; Kumar S; Chander S · Journal of diabetes and metabolic disorders · 2026
    Meta-analysis384 participants5 studies pooledMetabolism Boost forMagnesium
  17. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial.
    Rodríguez-Morán M; Guerrero-Romero F · Diabetes care · 2003
    Randomized trial63 participantsMetabolism Boost forMagnesium
  18. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
    Randomized trial70 participantsMetabolism Boost forMagnesium
  19. Insulin signal mimicry as a mechanism for the insulin-like effects of vanadium.
    Mehdi MZ; Pandey SK; Théberge JF; Srivastava AK · Cell biochemistry and biophysics · 2006
    Narrative reviewMetabolism Boost forVanadium
  20. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes.
    Cusi K; Cukier S; DeFronzo RA; Torres M; Puchulu FM; Redondo JC · The Journal of clinical endocrinology and metabolism · 2001
    Single-arm trial11 participantsMetabolism Boost forVanadium