Product Image

Buffered Vitamin C 1000 mg

Country Life
4.8
★ ★ ★ ★ ★
(1449 ratings)
Vitamin C 1000 mg
Flavonoid (mixture) 150 mg
Product Image
Score84
A practical large-supply vitamin C tablet with lemon bioflavonoids and separately listed minerals. The main weakness is less certain buffering than a true calcium ascorbate formula.
How scoring works
Quantity:250 Tablet(s) • (250 servings)
Goals:
Immunity
General Health
Skin Health
Anti-Inflammatory Support
Vision Support

Score 84

A practical large-supply vitamin C tablet with lemon bioflavonoids and separately listed minerals. The main weakness is less certain buffering than a true calcium ascorbate formula.
How scoring works

Also available as

1 option
100 servings Flavonoid (mixture) 150 mg, C 1000 mg • 100 Tablet(s) • 100 servings $19.19 ($0.19 per serving)
$29.99($0.11 per serving)
iHerb
$ 29.99
Vitacost
$ 29.99
Report prices

Analysis

The 1000 mg ascorbic acid serving provides substantial vitamin C for antioxidant, collagen, and normal immune support. Calcium carbonate may temper acidity, though the label does not present the vitamin C itself as a buffered ascorbate.

A 150 mg lemon bioflavonoid addition broadens the antioxidant profile. Individual compounds are not disclosed, so the precise flavonoid composition remains uncertain.

The 250-tablet supply is convenient for long-term users and supports favorable value. The formula still suits people who tolerate acidic vitamin C better than those specifically seeking a gentler mineral ascorbate.

Who is it for
  • Adults who tolerate ascorbic acid
  • Long-term vitamin C users
  • People wanting lemon bioflavonoids
Best for
  • Daily immune support
  • Antioxidant support
  • Large-bottle convenience

Pros

  • Full-gram vitamin C serving
  • 150 mg lemon bioflavonoids
  • 250-serving supply
  • Clear quantities for active minerals

Cons

  • Not explicitly a mineral ascorbate form
  • Only a small magnesium oxide amount
  • No constituent details for the bioflavonoids

Warnings

  • The 1000 mg ascorbic acid dose may aggravate reflux or cause loose stools
  • High-dose vitamin C deserves caution for people with a calcium oxalate stone history
  • Each serving adds 200 mg of calcium

Nutrient quality

84 Highest impact

The vitamin C amount is meaningful, and alkaline minerals may improve comfort. Standard ascorbic acid and low-value mineral forms limit form quality.

.

Ingredient transparency

84 Highest impact

Active names and amounts are clearly stated, with no hidden proprietary dose. Complete intake directions and a full inactive-ingredient list are not included in the supplied data.

.

Customer satisfaction

73 High impact

Supplied satisfaction metrics indicate a strong result with a meaningful response pool. Detailed experience themes are absent, so recurring complaints and real-world purpose fit remain uncertain.

.

Value for money

94 Highest impact

Serving value appears favorable relative to the disclosed form and amount. The focused formula avoids low-value extras.

.
Report analysis

Goals

Immunity
Immunity
Impact
Highest effect
A Goal FitA Strength of SupportC+ CoverageA Formula Quality
Magnesium · 12 mgVitamin C · 1000 mg

Vitamin C has a direct role in immune-cell activity, barrier integrity, and antioxidant protection. The 1,000 mg serving is paired with calcium, magnesium, and lemon bioflavonoids in a partially buffered design.

Magnesium oxide contributes little at 12 mg, so vitamin C remains the main functional active. Clear dosing and relevant supporting ingredients make this a strong targeted option rather than broad immune coverage.

Study evidence
Magnesium Supportive 8 studies
Vitamin C Supportive 53 studies
General Health
General Health
Impact
Highest effect
A Goal FitA Strength of SupportC+ CoverageA- Formula Quality
Magnesium · 12 mgVitamin C · 1000 mg

A substantial vitamin C serving directly supports antioxidant defenses, collagen production, and normal immune function. Calcium, magnesium, and lemon bioflavonoids add modest complementary support.

The mineral pairing may reduce acidity, although the product still relies on ordinary ascorbic acid. Clear amounts and a focused formula make its contribution easy to judge.

Study evidence
Magnesium Supportive 114 studies
Vitamin C Supportive 56 studies
Skin Health
Skin Health
Impact
Highest effect
A- Goal FitA- Strength of SupportB CoverageA- Formula Quality
Vitamin C · 1000 mg

Vitamin C directly supports collagen synthesis and provides antioxidant protection relevant to skin structure. The 1,000 mg amount is more than enough to cover its cofactor role, though oral absorption becomes less efficient at high single doses.

Lemon bioflavonoids complement antioxidant activity, while calcium buffering may improve stomach comfort for some users. The formula does not supply collagen peptides, ceramides, hyaluronic acid, or fatty acids for broader structural and barrier support.

Study evidence
Vitamin C Supportive 53 studies
Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B Goal FitA- Strength of SupportC CoverageA- Formula Quality
Vitamin C · 1000 mg

Vitamin C supplies substantial antioxidant support and can help limit oxidative stress that sustains inflammatory signaling. Lemon bioflavonoids add a compatible antioxidant component, while the minerals mainly buffer acidity.

The vitamin C amount is meaningful and fully disclosed, though ascorbic acid lacks an advanced delivery system. Magnesium oxide is present only in a token buffering amount, so the formula remains a focused antioxidant rather than broad inflammatory support.

Study evidence
Magnesium Supportive 41 studies
Vitamin C Supportive 50 studies
Vision Support
Vision Support
Impact
High effect
C Goal FitB+ Strength of SupportD- CoverageB Formula Quality
Vitamin C · 1000 mg

Vitamin C may support antioxidant protection in the lens and retina, especially as part of a broader nutrient combination. Added minerals partly buffer the ascorbic acid, but the formula still lacks macular pigments and retinal omega fats.

The substantial serving is clearly disclosed, while bioflavonoids add only modest extra vision relevance. A large vitamin C serving may cause stomach upset in sensitive users.

Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per serving
Vitamin C (Ascorbic Acid)
 1000 mg
Calcium (Calcium Carbonate)
 200 mg
Magnesium (Magnesium Oxide)
 12 mg
Lemon Bioflavonoids (Citrus limonum)
 150 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Vegetarian
Report overview
Vitamin C (Ascorbic Acid) · 1000 mg OverallScore80
C Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value

The target dose is paired with alkaline minerals that may improve comfort compared with plain ascorbic acid. The label clearly separates vitamin C and mineral amounts. Cost efficiency is favorable for this partially buffered approach.

View ingredientView products
Loading alternative details
89 Performance

C-500 Calcium Ascorbate-C

NOW
<p>The ingredient profile makes it a stronger quality-focused alternative for the same vitamin C goals. Buffered calcium ascorbate delivers a practical vitamin C amount with clear mineral disclosure and exceptional relative value. The small bioflavonoid addition is unlikely to contribute much but does not undermine the strong core formula.</p>
86 Performance

C

Swanson
<p>The ingredient profile makes it a stronger quality-focused alternative for the same vitamin C goals. Fully buffered calcium ascorbate provides a meaningful vitamin C serving with good stomach-comfort potential. The focused formula keeps the active nutrient clear and avoids decorative additions.</p>
87 Performance

Ester-C with Citrus Bioflavonoids

American Health
<p>The ingredient profile makes it a stronger quality-focused alternative for the same vitamin C goals. A buffered vitamin C form and a substantial citrus bioflavonoid amount create a simple, well-dosed antioxidant formula. Strong satisfaction signals and a long supply support value, though excipients and intake directions are not shown.</p>
89 Budget

Pure Buffered Calcium Ascorbate

NOW
<p>The lower serving cost makes it a more economical alternative while retaining the same vitamin C focus. the buffered mineral ascorbate form supplies a meaningful vitamin C amount with a digestive-comfort advantage over plain ascorbic acid. Clear active dosing and favorable serving value are strengths, though complete use directions and inactive ingredients are not supplied.</p>
87 Budget

100% Pure Vitamin C Powder

Swanson Premium Brand
<p>The lower serving cost makes it a more economical alternative while retaining the same vitamin C focus. The pure powder supplies a flexible, meaningful vitamin C serving with exceptional economy and no active padding. Plain ascorbic acid remains acidic, so sensitive users may prefer a buffered form.</p>
87 Budget

C 500 mg

Mason Natural
<p>The lower serving cost makes it a more economical alternative while retaining the same vitamin C focus. A simple moderate-dose tablet provides useful vitamin C at excellent relative value and with extensive aggregate feedback. Generic ascorbic acid and missing inactive-ingredient details are the main limitations.</p>
87 Value

Pure Buffered Magnesium Ascorbate

NOW
<p>The formula offers a more favorable balance of vitamin C quality and serving value than the original. Magnesium ascorbate provides a substantial fully buffered vitamin C serving with excellent relative value and clear mineral disclosure. Feedback volume is limited, and detailed use directions or non-active ingredients are not supplied.</p>
83 Value

C 500 mg

21st Century
<p>The formula offers a more favorable balance of vitamin C quality and serving value than the original. A large supply of straightforward vitamin C provides meaningful daily support with excellent value. Basic ascorbic acid and incomplete inactive-ingredient details keep the formula from feeling premium.</p>
84 Value

Ester-C 500 mg With Citrus Bioflavoinds

American Health
<p>The formula offers a more favorable balance of vitamin C quality and serving value than the original. Buffered Ester-C provides a substantial vitamin C serving with good stomach-comfort potential. Citrus bioflavonoids add compatible plant compounds without distracting from the core nutrient.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effect of Vitamin C Supplements on Respiratory Tract Infections: A Systematic Review and Meta-Analysis.
    Keya TA; Leela A; Fernandez K; Habib N; Rashid M · Current reviews in clinical and experimental pharmacology · 2022
    Meta-analysis10 studies pooledImmunity forVitamin C
  2. Vitamin C and contribution to the normal function of the immune system: evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusImmunity forVitamin C
  3. Vitamin C for the management of COVID-19: a systematic review and meta-analysis of randomized controlled trials.
    Abid H; Mushtaq I; Munir ABI; Shakil J; Vinjamuri S; Tadasare N; Kiran F; Muhammad Wali Mirza A; Fatima Khidri F; Shahid A; Ayyan M; Ehsan M; Cheema HA; Alsubari AMA; Sahra S; Siddiqi NI · Annals of medicine and surgery (2012) · 2026
    Meta-analysis9 studies pooledImmunity forVitamin C
  4. Enhanced Vitamin C Delivery: A Systematic Literature Review Assessing the Efficacy and Safety of Alternative Supplement Forms in Healthy Adults.
    Calder PC; Kreider RB; McKay DL · Nutrients · 2025
    Systematic review13 studies pooledImmunity forVitamin C
  5. Dietary magnesium intake is inversely associated with serum C-reactive protein levels: meta-analysis and systematic review.
    Dibaba DT; Xun P; He K · European journal of clinical nutrition · 2014
    Meta-analysis32,918 participants7 studies pooledAnti-Inflammatory Support forMagnesium
  6. Efficacy and safety of magnesium glycinate as add on therapy in hypomagnesemic asthma and chronic obstructive pulmonary disease patients: A randomised controlled study assessing inflammatory biomarkers.
    Maddirevula MK; Rajanandh MG; Wesley B · Pulmonary pharmacology & therapeutics · 2026
    Randomized trial224 participantsAnti-Inflammatory Support forMagnesium
  7. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.
    Razzaghi R; Pidar F; Momen-Heravi M; Bahmani F; Akbari H; Asemi Z · Biological trace element research · 2018
    Randomized trial70 participantsAnti-Inflammatory Support forMagnesium
  8. The effect of long-term magnesium intake on inflammatory markers in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
    Wang W; Wang J; Yang Y; Shi Y · Frontiers in nutrition · 2025
    Meta-analysis444 participants8 studies pooledAnti-Inflammatory Support forMagnesium
  9. Effect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled Trials.
    Veronese N; Pizzol D; Smith L; Dominguez LJ; Barbagallo M · Nutrients · 2022
    Meta-analysis889 participants17 studies pooledAnti-Inflammatory Support forMagnesium
  10. Efficacy of Vitamin C as Glucocorticoid Substitute for Reducing Pain and Inflammation After Total Hip Arthroplasty: A Randomized Controlled Trial.
    Jiang W; Xu H; Jiang X; Zhan Y; Ju Y; Xie J; Huang Z; Huang Q; Pei F · The Journal of bone and joint surgery. American volume · 2025
    Randomized trial107 participantsAnti-Inflammatory Support forVitamin C
  11. The Impact of Vitamin C on Analgesic, Anti-inflammatory, and Hemostatic Outcomes After Total Hip and Knee Arthroplasty: A Systematic Review and Meta-Analysis.
    Moftakhari Hajimirzaei S; Bagherzadeh Cham M; Dolikhani M; Tabatabaee SM; Ebrahimpour A · The archives of bone and joint surgery · 2026
    Meta-analysis1,162 participants10 studies pooledAnti-Inflammatory Support forVitamin C
  12. The impact of vitamin C supplementation on the perioperative outcomes after total hip and knee arthroplasty: a systematic review and meta-analysis.
    Liu X; Guo J; Li Y; Yang Y; Liu M; Gao Q; Yang Y; Wu X; Yue C · BMC musculoskeletal disorders · 2026
    Meta-analysis852 participants8 studies pooledAnti-Inflammatory Support forVitamin C
  13. Therapeutic Impact of Ascorbic Acid on Oral and Periodontal Tissues: A Systematic Literature Review.
    Ruzijevaite G; Acaite E; Jagelaviciene E · Medicina (Kaunas, Lithuania) · 2025
    Systematic review811 participants17 studies pooledAnti-Inflammatory Support forVitamin C
  14. Oral vitamin C administration reduces early recurrence rates after electrical cardioversion of persistent atrial fibrillation and attenuates associated inflammation.
    Korantzopoulos P; Kolettis TM; Kountouris E; Dimitroula V; Karanikis P; Pappa E; Siogas K; Goudevenos JA · International journal of cardiology · 2005
    Randomized trial44 participantsAnti-Inflammatory Support forVitamin C
  15. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledGeneral Health forMagnesium
  16. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsGeneral Health forMagnesium
  17. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsGeneral Health forMagnesium
  18. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsGeneral Health forMagnesium
  19. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsGeneral Health forMagnesium
  20. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  21. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  22. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  23. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  24. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  25. Hypomagnesemia Is a Risk Factor for Infections after Kidney Transplantation: A Retrospective Cohort Analysis.
    Odler B; Deak AT; Pregartner G; Riedl R; Bozic J; Trummer C; Prenner A; Söllinger L; Krall M; Höflechner L; Hebesberger C; Boxler MS; Berghold A; Schemmer P; Pilz S; Rosenkranz AR · Nutrients · 2021
    Cohort study376 participantsImmunity forMagnesium
  26. Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study.
    Nouri-Majd S; Ebrahimzadeh A; Mousavi SM; Zargarzadeh N; Eslami M; Santos HO; Taghizadeh M; Milajerdi A · Frontiers in nutrition · 2022
    Cross-sectional study250 participantsImmunity forMagnesium
  27. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.
    Chaigne-Delalande B; Li FY; O'Connor GM; Lukacs MJ; Jiang P; Zheng L; Shatzer A; Biancalana M; Pittaluga S; Matthews HF; Jancel TJ; Bleesing JJ; Marsh RA; Kuijpers TW; Nichols KE; Lucas CL; Nagpal S; Mehmet H; Su HC; Cohen JI; Uzel G; Lenardo MJ · Science (New York, N.Y.) · 2013
    Single-arm trialImmunity forMagnesium
  28. Effect of magnesium on granulocyte function and on the exercise induced inflammatory response.
    Mooren FC; Golf SW; Völker K · Magnesium research · 2003
    Randomized trialImmunity forMagnesium
  29. Maternal and neonatal outcomes following magnesium sulfate in the setting of chorioamnionitis: a meta-analysis.
    Pergialiotis V; Sapantzoglou I; Rodolaki K; Varthaliti A; Theodora M; Antsaklis P; Thomakos N; Stavros S; Daskalakis G; Papapanagiotou A · Archives of gynecology and obstetrics · 2024
    Meta-analysis6,559 participants8 studies pooledImmunity forMagnesium
  30. Therapeutic effects of high-dose vitamin C supplementation in patients with COVID-19: a meta-analysis.
    Sun L; Zhao JH; Fan WY; Feng B; Liu WW; Chen RQ; Ban C; Dang AG; Wang M; Luo KT; Zhou GY; Yu FF; Ba Y · Nutrition reviews · 2024
    Meta-analysis2,334 participants14 studies pooledImmunity forVitamin C
  31. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
    Abioye AI; Bromage S; Fawzi W · BMJ global health · 2021
    Meta-analysisImmunity forVitamin C
  32. New evidence for antioxidant properties of vitamin C.
    Vojdani A; Bazargan M; Vojdani E; Wright J · Cancer detection and prevention · 2001
    Randomized trial20 participantsImmunity forVitamin C
  33. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  34. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  35. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  36. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  37. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  38. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsVision Support forVitamin C
  39. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyVision Support forVitamin C
  40. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewVision Support forVitamin C
  41. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsVision Support forVitamin C
  42. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsVision Support forVitamin C