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Women's Wellness

Bio Nutrition
4.8
★ ★ ★ ★ ★
(92 ratings)
Vitamin A 5000 IU
Vitamin E 30 IU
Biotin 300 mcg
Vitamin D 400 IU
Vitamin B5 25 mg
Folate 400 mcg
Choline 50 mg
Product Image
Score52
Several good vitamin forms are overshadowed by numerous opaque blends and unclear mineral coverage. The product offers breadth on paper but limited evaluable depth.
How scoring works
Quantity:60 Tablet(s) • (60 servings)
Goals:
General Health
Hair Health
Skin Health

Score 52

Several good vitamin forms are overshadowed by numerous opaque blends and unclear mineral coverage. The product offers breadth on paper but limited evaluable depth.
How scoring works
$15.73($0.26 per serving)
iHerb
$ 15.73
Pure Formulas
$ 20.97
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Analysis

Beta-carotene, vitamin D3, natural vitamin E, hydroxocobalamin, biotin, and calcium ascorbate are thoughtful inclusions. The B-vitamin pattern is more substantial than the mineral support shown.

Five proprietary blends hide individual ingredients and doses, so their claimed roles cannot be assessed. A minerals entry without useful quantities and a modest vitamin D amount leave important coverage unclear.

The formula may suit adults wanting a vitamin-and-B-complex blend with botanical extras. Transparency-focused users or those needing targeted mineral amounts should choose a more fully itemized product.

Who is it for
  • Adult women seeking broad vitamin support
  • Users who value B-vitamin coverage
  • People comfortable with proprietary blends
Best for
  • General vitamin intake
  • B-vitamin support
  • Basic antioxidant coverage

Pros

  • Uses vitamin D3 and natural vitamin E
  • Includes hydroxocobalamin B12
  • Broad vitamin profile

Cons

  • Five proprietary blends hide doses
  • Mineral coverage is unclear
  • Vitamin D amount is modest

Warnings

  • Review the full herbal blend before use with prescription medicines
  • The vitamin B6 amount should be included when combining B-complex products
  • Beta-carotene is not a substitute for a clinically directed preformed vitamin A supplement

Nutrient quality

63 Moderate impact

Beta-carotene, vitamin D3, natural vitamin E, hydroxocobalamin, and buffered vitamin C support good form quality, and several B vitamins are meaningful, but vitamin D is modest and blend ingredients cannot be judged individually. Most vitamin amounts are reasonable, though vitamin B6 is fairly assertive for routine use, while five proprietary blends create a substantial risk of low-value padding.

Ingredient transparency

35 Situational impact

Vitamin amounts are listed, but minerals and every specialty blend lack individual doses. Five proprietary blends hide the ingredients and amounts that make up much of the formula, while inactive tablet ingredients are not included in the supplied details.

Customer satisfaction

65 High impact

The supplied aggregate satisfaction metric is strong, and the feedback volume offers some support but is less robust than heavily reviewed alternatives. No review excerpts were provided, so recurring complaints and purpose-specific experiences cannot be checked.

Value for money

50 Moderate impact

Good vitamin forms and low serving cost help, but extensive hidden blends reduce confidence in quality. The serving is inexpensive, though much of the specialty formula cannot be evaluated, while multiple opaque blends may inflate the formula without verifiable benefit.

Report analysis

Goals

General Health
Impact
Moderate effect
B- Goal FitD Strength of SupportC+ CoverageD- Formula Quality
Folate · 400 mcgVitamin B12 · 50 mcgVitamin D · 400 IUVitamin C · 60 mg

A wide vitamin profile gives this women-focused formula reasonable daily-health breadth. Vitamin D3, folate, B12, vitamin C, vitamin E, choline, and biotin cover several foundational functions.

Vitamin D is modest, folate is ordinary folic acid, and five proprietary blends obscure many ingredient amounts. The broad design therefore looks more complete on the label than its verifiable dosing supports.

Study evidence
Folate Supportive 80 studies
Vitamin C Supportive 56 studies
Vitamin D Supportive 115 studies
Hair Health
Impact
Moderate effect
C Goal FitD+ Strength of SupportC CoverageF Formula Quality
Biotin · 300 mcgVitamin D · 400 IUVitamin C · 60 mg

Biotin, vitamin D, folate, vitamin E, and beta-carotene address several nutritional factors linked to hair quality. Most amounts suit general maintenance, while vitamin D and biotin are modest for targeted use.

Five proprietary blends prevent a reliable assessment of the amino-acid, mineral, and botanical contributions. The broad formula may cover nutrient gaps but lacks enough transparent depth to support its many claimed pathways.

Study evidence
Biotin Supportive 4 studies
Folate Mixed 15 studies
Vitamin D Disputed 34 studies
Vitamin E No effect 3 studies
Impact
Moderate effect
C- Goal FitD+ Strength of SupportC- CoverageF Formula Quality
Vitamin C · 60 mgVitamin E · 30 IU

Vitamin A, vitamin E, vitamin C, biotin, and B vitamins cover cell turnover and antioxidant nutrition. Several proprietary blends may add other pathways, but their contents cannot be judged.

The main vitamins are suited to maintenance rather than targeted structural or hydration support. Five opaque blends and numerous general-wellness ingredients make the formula diffuse and difficult to evaluate.

Study evidence
Biotin Supportive 10 studies
Vitamin A Supportive 106 studies
Vitamin C Supportive 53 studies
Vitamin E Supportive 38 studies

Ingredients

IngredientAmount per serving
Vitamin A (Beta-Carotene)
5000 IU
Vitamin D3 (Cholecalciferol)
400 IU
Vitamin E (D-Alpha-Tocopherol)
30 IU
Vitamin B1 (Thiamine)
5 mg
Vitamin B2 (Riboflavin)
5 mg
Vitamin B3 (Niacinamide)
7.5 mg
Vitamin B5 (Pantothenic Acid)
25 mg
Vitamin B6 (Pyridoxine)
12.5 mg
Vitamin B12 (Hydroxocobalamin)
50 mcg
D-Biotin
300 mcg
Folic Acid
400 mcg
Choline Bitartrate
50 mg
Inositol
50 mg
PABA
5 mg
C (Calcium Ascorbate)
60 mg
Minerals
0 NP
Co Factor Proprietary Blend
100 mg
Amino Acid Proprietary Blend
100 mg
Super Food Proprietary Blend
100 mg
Herbal Proprietary Blend
100 mg
Digestive Proprietary Blend
100 mg
Gluten Free Dairy Free Sugar Free Women 18–50
Report overview
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

Beta-carotene offers a provitamin form, but its natural source is not identified. The dry format lacks a lipid carrier, so absorption depends on food. The 5,000 IU serving falls within the preferred efficacy and safety range, and the vitamin a delivered per serving offers favorable cost efficiency.

D Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value

Natural d-alpha vitamin E supports favorable biological activity. Mixed tocopherol diversity and tocotrienols are both absent. The amount is suited to routine maintenance rather than therapeutic use, while confirmed natural sourcing and a low serving cost create strong value.

Biotin · 300 mcg OverallScore63
A Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

Explicit d-biotin improves form confidence, but the amount remains too low for concentrated hair and nail support. The tablet base is acceptable, while several proprietary companion blends limit broader formula transparency. Neutral value is appropriate because the product supplies many nutrients and botanicals beyond biotin.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Infatuation With Biotin Supplementation: Is There Truth Behind Its Rising Popularity? A Comparative Analysis of Clinical Efficacy versus Social Popularity.
    Soleymani T; Lo Sicco K; Shapiro J · Journal of drugs in dermatology : JDD · 2018
    Narrative reviewHair Health forBiotin
  2. Vitamins A, B, C, and D: A Short Review for the Dermatologist.
    Coerdt KM; Goggins CA; Khachemoune A · Alternative therapies in health and medicine · 2021
    Narrative reviewHair Health forBiotin
  3. Low serum biotinidase activity in children with valproic acid monotherapy.
    Schulpis KH; Karikas GA; Tjamouranis J; Regoutas S; Tsakiris S · Epilepsia · 2001
    Clinical trial125 participantsHair Health Skin Health forBiotin
  4. The Role of Sesbania grandiflora-Derived Biotin and Bambusa arundinacea-Derived Silica Extracts in Promoting Hair, Skin, and Nail Health: A Randomized, Double-Blind, Placebo-Controlled Clinical Study.
    Patel MN; Maheshvari J; Patel N · Cureus · 2025
    Randomized trial105 participantsHair Health Skin Health forBiotin
  5. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsGeneral Health forFolate
  6. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsGeneral Health forFolate
  7. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsGeneral Health forFolate
  8. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewGeneral Health forFolate
  9. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledGeneral Health forFolate
  10. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledGeneral Health forVitamin C
  11. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusGeneral Health forVitamin C
  12. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsGeneral Health forVitamin C
  13. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsGeneral Health forVitamin C
  14. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsGeneral Health forVitamin C
  15. Vitamin D supplementation for prevention of mortality in adults.
    Bjelakovic G; Gluud LL; Nikolova D; Whitfield K; Wetterslev J; Simonetti RG; Bjelakovic M; Gluud C · The Cochrane database of systematic reviews · 2014
    Meta-analysis95,286 participants159 studies pooledGeneral Health forVitamin D
  16. Effect of vitamin D on gastrointestinal symptoms and health-related quality of life in irritable bowel syndrome patients: a randomized double-blind clinical trial.
    Abbasnezhad A; Amani R; Hajiani E; Alavinejad P; Cheraghian B; Ghadiri A · Neurogastroenterology and motility · 2018
    Randomized trial90 participantsGeneral Health forVitamin D
  17. The impact of vitamin D administration on mortality in COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials.
    Kow CS; Ramachandram DS; Hasan SS; Wong Z; Thiruchelvam K · Inflammopharmacology · 2024
    Meta-analysis2,495 participants19 studies pooledGeneral Health forVitamin D
  18. Vitamin D Status and Mortality: A Systematic Review of Observational Studies.
    Heath AK; Kim IY; Hodge AM; English DR; Muller DC · International journal of environmental research and public health · 2019
    Systematic review84 studies pooledGeneral Health forVitamin D
  19. Meta-analysis of long-term vitamin D supplementation on overall mortality.
    Zheng Y; Zhu J; Zhou M; Cui L; Yao W; Liu Y · PloS one · 2014
    Meta-analysis42 studies pooledGeneral Health forVitamin D
  20. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  21. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate
  22. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  23. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  24. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  25. Increased prevalence of vitamin D deficiency in patients with alopecia areata: a systematic review and meta-analysis.
    Lee S; Kim BJ; Lee CH; Lee WS · Journal of the European Academy of Dermatology and Venereology : JEADV · 2018
    Meta-analysis2,039 participants14 studies pooledHair Health forVitamin D
  26. Intralesional vitamin D3 in treatment of alopecia areata: A randomized controlled clinical trial.
    Rashad AF; Elgamal E; Fouda I · Journal of cosmetic dermatology · 2022
    Randomized trial60 participantsHair Health forVitamin D
  27. Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
    Alsaati AA; Kaliyadan F; Alsaadoun D; Alzakry LM; Alzabadin RA; Hakami TH; Rubaian NFB · Indian dermatology online journal · 2025
    Meta-analysisHair Health forVitamin D
  28. Topical calcipotriol vs narrowband ultraviolet B in treatment of alopecia areata: a randomized-controlled trial.
    El Taieb MA; Hegazy EM; Ibrahim HM; Osman AB; Abualhamd M · Archives of dermatological research · 2020
    Randomized trial60 participantsHair Health forVitamin D
  29. Serum 25 hydroxyvitamin D in non-scarring alopecia: A systematic review and meta-analysis.
    Chen Y; Dong X; Wang Y; Li Y; Xiong L; Li L · Journal of cosmetic dermatology · 2024
    Meta-analysis10,670 participants23 studies pooledHair Health forVitamin D
  30. Effects of tocotrienol supplementation on hair growth in human volunteers.
    Beoy LA; Woei WJ; Hay YK · Tropical life sciences research · 2014
    Randomized trial38 participantsHair Health forVitamin E
  31. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forVitamin E
  32. Evaluation of the Safety and Effectiveness of Nutritional Supplements for Treating Hair Loss: A Systematic Review.
    Drake L; Reyes-Hadsall S; Martinez J; Heinrich C; Huang K; Mostaghimi A · JAMA dermatology · 2023
    Systematic review30 studies pooledHair Health forVitamin E
  33. Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters.
    Aksac SE; Bilgili SG; Yavuz GO; Yavuz IH; Aksac M; Karadag AS · International journal of dermatology · 2021
    Non-randomized trial60 participantsSkin Health forBiotin
  34. Generalized seborrhoeic dermatitis. Clinical and therapeutic data of 25 patients.
    Messaritakis J; Kattamis C; Karabula C; Matsaniotis N · Archives of disease in childhood · 1976
    Non-randomized trial25 participantsSkin Health forBiotin
  35. Holocarboxylase synthetase deficiency: novel clinical and molecular findings.
    Tammachote R; Janklat S; Tongkobpetch S; Suphapeetiporn K; Shotelersuk V · Clinical genetics · 2010
    Case series4 participantsSkin Health forBiotin
  36. Efficacy and Tolerability of Topical 0.1% Stabilized Bioactive Retinol for Photoaging: A Vehicle-Controlled Integrated Analysis.
    Farris P; Berson D; Bhatia N; Goldberg D; Lain E; Mariwalla K; Zeichner J; Miller D; McGuire T; Kizoulis M · Journal of drugs in dermatology : JDD · 2024
    Meta-analysis471 participants6 studies pooledSkin Health forVitamin A
  37. Tensile properties and contours of aging facial skin. A controlled double-blind comparative study of the effects of retinol, melibiose-lactose and their association.
    Piérard-Franchimont C; Castelli D; Cromphaut IV; Bertin C; Ries G; Cauwenbergh G; Piérard GE · Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2016
    Randomized trial120 participantsSkin Health forVitamin A
  38. Antiaging action of retinol: from molecular to clinical.
    Bellemère G; Stamatas GN; Bruère V; Bertin C; Issachar N; Oddos T · Skin pharmacology and physiology · 2009
    Randomized trial48 participantsSkin Health forVitamin A
  39. An Updated Review of Topical Tretinoin in Dermatology: From Acne and Photoaging to Skin Cancer.
    Balado-Simó P; Morgado-Carrasco D; Gómez-Armayones S; López-Ferrer A; Barco D; Ferrándiz-Pulido C; Podlipnik S · Journal of clinical medicine · 2025
    Narrative reviewSkin Health forVitamin A
  40. Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging: A Randomized, Double-Blinded, Active- and Vehicle-Controlled Clinical Trial.
    Chang H; Tao K; Yang Y; Wang Y; Ge M; Wang X; Tang S; Yu H · Journal of cosmetic dermatology · 2025
    Randomized trialSkin Health forVitamin A
  41. Evaluation of the anti-wrinkle effect of an ascorbic acid-loaded dissolving microneedle patch via a double-blind, placebo-controlled clinical study.
    Lee C; Yang H; Kim S; Kim M; Kang H; Kim N; An S; Koh J; Jung H · International journal of cosmetic science · 2017
    Randomized trial23 participantsSkin Health forVitamin C
  42. Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial.
    Machado BHB; Frame J; Zhang J; Najlah M · Aesthetic plastic surgery · 2021
    Randomized trial149 participantsSkin Health forVitamin C
  43. Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma.
    Burke B; Bailie JE · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Randomized trial25 participantsSkin Health forVitamin C
  44. Vitamin C improves healing of foot ulcers: a randomised, double-blind, placebo-controlled trial.
    Gunton JE; Girgis CM; Lau T; Vicaretti M; Begg L; Flood V · The British journal of nutrition · 2022
    Randomized trial16 participantsSkin Health forVitamin C
  45. Dietary nutrient intakes and skin-aging appearance among middle-aged American women.
    Cosgrove MC; Franco OH; Granger SP; Murray PG; Mayes AE · The American journal of clinical nutrition · 2007
    Cross-sectional study4,025 participantsSkin Health forVitamin C
  46. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis.
    Javanbakht MH; Keshavarz SA; Djalali M; Siassi F; Eshraghian MR; Firooz A; Seirafi H; Ehsani AH; Chamari M; Mirshafiey A · The Journal of dermatological treatment · 2011
    Randomized trial45 participantsSkin Health forVitamin E
  47. Serum vitamin E levels and chronic inflammatory skin diseases: A systematic review and meta-analysis.
    Liu X; Yang G; Luo M; Lan Q; Shi X; Deng H; Wang N; Xu X; Zhang C · PloS one · 2022
    Meta-analysis20 studies pooledSkin Health forVitamin E
  48. Evidence-Based Nutritional Interventions in Wound Care.
    Saeg F; Orazi R; Bowers GM; Janis JE · Plastic and reconstructive surgery · 2021
    Systematic review2,339 participants36 studies pooledSkin Health forVitamin E
  49. Effects of tocotrienol on aging skin: A systematic review.
    Ghazali NI; Mohd Rais RZ; Makpol S; Chin KY; Yap WN; Goon JA · Frontiers in pharmacology · 2022
    Systematic reviewSkin Health forVitamin E
  50. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans.
    Stahl W; Heinrich U; Jungmann H; Sies H; Tronnier H · The American journal of clinical nutrition · 2000
    Randomized trialSkin Health forVitamin E