Hawthorn

botanical

Hawthorn (Crataegus species) consists of thorny shrubs and trees native to temperate regions across North America, Europe, and Asia. Its berries, leaves, and flowers have been used for centuries in traditional herbal medicine to support the heart and circulatory system. It remains a staple in European folk traditions for various heart-related needs. The properties of Hawthorn are attributed to bioactive compounds, including flavonoids like vitexin, hyperoside, and rutin, along with oligomeric proanthocyanidins (OPCs). These antioxidants protect cells from oxidative stress. Proposed mechanisms include supporting coronary blood flow, strengthening heart contractions, promoting vasodilation, and modulating blood pressure. Scientific research focuses on its potential to support heart muscle function, blood vessel integrity, and blood pressure regulation. While not a substitute for conventional treatment, it is often used as a supportive botanical for maintaining a healthy heart and circulatory system.

Natural sources
Berries of the Hawthorn shrub/treeLeaves of the Hawthorn shrub/treeFlowers of the Hawthorn shrub/tree

Ingredient forms

No public comparison lists found.

Timing & Intake
AnytimeWith foodTake with May be taken with a meal to minimize potential stomach upset.
Often taken daily to provide consistent cardiovascular support.
Optimal Dosage
Minimum250 mg
Maximum500 mg
Safety & Toxicity
4 safety notes
  • Consult a healthcare professional before use, especially if you have a heart condition, are pregnant, nursing, or taking any medications.
  • May affect blood pressure and heart rate; monitor closely if you have pre-existing cardiovascular issues.
  • Discontinue use if adverse reactions occur.
  • Do not exceed recommended dosage.
Goals
Cardiovascular Support
Impact
High effect
Typical dose:300–1000 mg

Hawthorn extract has a long history of use and is supported by modern clinical trials for its positive effects on heart function. Its active compounds, including flavonoids and procyanidins, enhance coronary artery blood flow, improve the strength of the heart's contractions, and provide antioxidant protection to cardiac tissue.

Focuses on
Exercise toleranceHeart functionBlood pressureSymptom reliefHeart rhythm
Most relevant for
Adults with mild heart failure (NYHA II) or those managing mild hypertension who seek to support their heart function and physical capacity.

Potential benefits

  • Improved Exercise Tolerance.Clinical trials demonstrate that standardized hawthorn extracts can increase exercise capacity and reduce exertion-related fatigue in individuals with mild heart failure.
  • Blood Pressure Support.Meta-analyses and specific trials indicate hawthorn may help lower systolic and diastolic blood pressure, particularly in those with hypertension or diabetes.
  • Heart Rhythm Support.Large observational studies suggest that certain hawthorn extracts are associated with a lower incidence of heart rhythm issues like tachycardia and atrial fibrillation.

Limitations

  • Inconsistent Blood Pressure Results.Results are mixed, with several high-quality trials showing no significant improvement in blood pressure or blood vessel dilation compared to a placebo.
  • Specific Study Populations.Most supportive evidence is limited to individuals with established mild heart failure (NYHA II); benefits for general heart disease prevention are not proven.
  • Preparation Dependency.Efficacy is primarily linked to specific standardized extracts used in clinical research, and results may not generalize to all hawthorn supplements or plant parts.
Things to consider

Hawthorn may significantly increase the risk of bleeding after heart surgery; it is essential to discontinue use before scheduled surgical procedures and consult a physician.

Study evidence

28 studies

Hawthorn may improve some heart-failure symptoms, exercise tolerance or blood-pressure measures, but results depend on the preparation and population. Prevention of cardiovascular complications is not established, and an observational link with bleeding after heart surgery raises a specific safety concern.

View goal
Heart Health
Impact
Situational effect
Typical dose:300–1200 mg

Hawthorn contains flavonoids and proanthocyanidins that exert a range of positive effects on the heart. It is particularly effective for improving symptoms of mild to moderate heart failure, such as fatigue and shortness of breath, by enhancing overall cardiac performance.

Focuses on
Exercise capacityHeart failure symptomsBlood pressureCardiac efficiencyBreathlessness
Most relevant for
Adults with mild-to-moderate heart failure symptoms or high blood pressure seeking supportive botanical options alongside medical care.

Potential benefits

  • Improved exercise tolerance.Meta-analyses indicate that standardized extracts can increase maximal workload and total exercise time in patients with mild heart failure.
  • Reduced heart failure symptoms.Research suggests hawthorn may help alleviate shortness of breath and fatigue in people with NYHA Class II-III heart failure.
  • Systolic blood pressure support.Clinical evidence from meta-analyses suggests a significant reduction in systolic blood pressure when used consistently for two to six months.

Limitations

  • Uncertainty with standard therapy.Trials have found no significant functional benefit when hawthorn is added to modern, evidence-based heart failure medications.
  • Lack of preventive evidence.Studies primarily involve patients with existing heart conditions, leaving its role in primary heart disease prevention for healthy adults unproven.
  • Mixed results on risk factors.Clinical findings are inconsistent regarding hawthorn's ability to lower cholesterol or reduce markers of inflammation compared to placebo.
Things to consider

Consult a healthcare professional before use if taking prescription heart medications, as some clinical trials reported more non-cardiac adverse events when added to standard therapy.

Study evidence

27 studies

Some standardized hawthorn extracts may improve symptoms and exercise tolerance in mild heart failure, but the evidence is inconsistent. Adding hawthorn to established heart-failure treatment has not reliably improved daily function, and broader protection against heart disease remains unproven.

View goal

Studies

Research connections will load here.
Interactions

Positive Interactions

Magnesium
Magnesium is crucial for heart health and blood pressure regulation, complementing Hawthorn's cardiovascular effects.
Potassium
Potassium helps balance fluids and maintain healthy blood pressure, working synergistically with Hawthorn for cardiovascular support.
Coenzyme Q-10
CoQ10 is vital for cellular energy production in the heart, and its antioxidant properties can complement Hawthorn's cardiovascular benefits.
Arginine
Arginine is a precursor to nitric oxide, which promotes vasodilation, potentially enhancing Hawthorn's effects on blood flow and blood pressure.
Omega-3
Omega-3 fatty acids support overall cardiovascular health, including healthy blood pressure and inflammation, which can complement Hawthorn's actions.
Vitamin C
A powerful antioxidant that supports cardiovascular health and blood vessel integrity, potentially enhancing the antioxidant effects of Hawthorn's flavonoids.
Vitamin E
Another antioxidant vitamin that protects cells from oxidative stress, complementing Hawthorn's antioxidant profile.
Resveratrol
Known for its cardiovascular and antioxidant properties, Resveratrol can work synergistically with Hawthorn to support heart health.
Turmeric
Turmeric, through its active compound Curcumin, offers anti-inflammatory and antioxidant properties that can support overall cardiovascular health, complementing Hawthorn.
Ginkgo
Ginkgo is known for improving blood circulation, which could complement Hawthorn's positive effects on the cardiovascular system.
Sources

Up to five highest-ranked published examples per goal. Study counts and charts include all published studies for the connection.

  1. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany.
    Wyss C; Gündling PW; Kostev K · Scientific reports · 2024
    Cohort study9,100 participantsCardiovascular Support
  2. Hawthorn (Crataegus spp.) Clinically Significantly Reduces Blood Pressure in Hypertension: A Meta-Analysis of Randomized Placebo-Controlled Clinical Trials.
    Szikora Z; Mátyus RO; Szabó BV; Csupor D; Tóth B · Pharmaceuticals (Basel, Switzerland) · 2025
    Meta-analysis428 participants6 studies pooledHeart HealthCardiovascular Support
  3. A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Crataegisan) in the treatment of patients with congestive heart failure NYHA II.
    Degenring FH; Suter A; Weber M; Saller R · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2003
    Randomized trial143 participantsCardiovascular Support
  4. [Crataegus Special Extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II)].
    Weikl A; Assmus KD; Neukum-Schmidt A; Schmitz J; Zapfe G; Noh HS; Siegrist J · Fortschritte der Medizin · 1996
    Randomized trial136 participantsCardiovascular Support
  5. Prospective, comparative cohort studies and their contribution to the benefit assessments of therapeutic options: heart failure treatment with and without Hawthorn special extract WS 1442.
    Habs M · Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine · 2005
    Cohort study952 participantsCardiovascular Support
  6. [Actions of standardized extracts of Crataegus berries on exercise tolerance and quality of life in patients with congestive heart failure].
    Rietbrock N; Hamel M; Hempel B; Mitrovic V; Schmidt T; Wolf GK · Arzneimittel-Forschung · 2001
    Randomized trial88 participantsHeart Health
  7. Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials.
    Pittler MH; Schmidt K; Ernst E · The American journal of medicine · 2003
    Meta-analysis632 participants13 studies pooledHeart Health
  8. Clinical efficacy of crataegus extract WS 1442 in congestive heart failure NYHA class II.
    Zapfe jun G · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2002
    Randomized trial40 participantsHeart Health
  9. Baseline severity but not gender modulates quantified Crataegus extract effects in early heart failure--a pooled analysis of clinical trials.
    Eggeling T; Regitz-Zagrosek V; Zimmermann A; Burkart M · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2012
    Meta-analysis687 participants10 studies pooledHeart Health