GABA 500 mg

GABA 500 mg

NOW4.7 (83,161 ratings)
Format:Capsule Quantity: 100 Capsule(s) · 100 servings
Goals

Product analysis

63 out of 100

GABA 500 mg may help with short-term calming, but evidence for lasting stress relief or better sleep remains limited.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality27

The GABA preparation is unnamed, making it difficult to match to preparation-specific findings. Vitamin B6 is identified, but its comparative form quality remains uncertain.

Ingredient Transparency81

Both ingredient amounts are stated clearly. Vitamin B6’s form is named, while the GABA preparation is not, limiting comparisons with other GABA supplements.

Value For Money78

The GABA contribution offers favorable value at the serving cost. Value for vitamin B6 remains uncertain without a usable comparison.

Customer Satisfaction91

Customer ratings are very positive across a very large review base. The broad feedback shows satisfaction without establishing lasting benefits for stress or sleep.

Product Focus64

GABA is the main possible calming ingredient, with evidence limited to small and specific settings. The modest vitamin B6 contribution does not add a meaningful separate role for sleep.

Format
Capsule
Container
100 Capsule(s)
Per serving
$0.08
Customer rating
4.7 · 83,161 ratings
Report analysis

Goals

Mood Support
Impact
Moderate effect
A+ Ingredient FitF PathwaysD+ EvidenceA+ Formulation Logic
Vitamin B6 · 2 mg

GABA is associated with calming signals, but swallowing it doesn't necessarily improve everyday mood. Benefits from a particular fermented preparation can't be assumed for every GABA ingredient. Whether this preparation helps you feel less tense or improves emotional well-being remains unclear.

How this product is rated for Mood Support

Ingredient fit96

GABA supplies the main mood connection. Its practical contribution depends on the context described here.
Goal fit
GABA supplies the main connection with mood here.
Dose adequacy
GABA provides 500 mg per serving. The amount alone does not predict mood improvement.

Pathways17

The main connection is with calming signals; that connection alone does not guarantee feeling calmer.
Depth
The main connection is with calming signals; that connection alone does not guarantee feeling calmer.
Breadth
The ingredients relate to particular mood processes; this does not predict a broad improvement in emotional well-being.

Evidence53

Effects of a particular fermented GABA preparation cannot automatically be transferred to generic GABA.
Evidence strength
Effects of a particular fermented GABA preparation cannot automatically be transferred to generic GABA.
Studied preparation
Ingredient identity alone does not remove the limits on who may benefit.

Formulation logic100

No particular ingredient conflict is identified, and no additional partner is required by the described ingredient relationships.
Partner coverage
No additional partner is required by the ingredient relationships described here.
Conflicts
No particular conflict between the declared ingredients is identified.
Effective doses
GABA provides 500 mg per serving. A declared amount does not guarantee an individual benefit.
Study evidence
GABA Supportive 12 studies
Vitamin B6 Supportive 19 studies
Sleep Support
Impact
Moderate effect
A+ Ingredient FitF PathwaysD+ EvidenceA+ Formulation Logic

GABA may offer some calming support that could help with winding down, though its direct contribution to better sleep remains uncertain. The product's 500 mg GABA serving is the clearest sleep-related ingredient.

Vitamin B6 is also listed, but its 2 mg amount is too small to add a meaningful separate role. The formula therefore stays focused on GABA's possible calming contribution.

How this product is rated for Sleep Support

Ingredient fit96

GABA is the only active with a meaningful sleep-related role here; the listed vitamin B6 amount is too small to add another.
Goal fit
GABA is the only credited sleep-related ingredient; vitamin B6 doesn't add a meaningful role at the listed amount.
Dose adequacy
The serving provides 500 mg GABA and 2 mg vitamin B6; the small B6 amount isn't counted as a sleep contribution.

Pathways12

GABA's possible contribution is calming, while the formula doesn't provide a distinct timing or sleep-signaling role.
Depth
GABA's possible role is calming, which may help with winding down before sleep.
Breadth
The formula has a calming role but doesn't add distinct support for sleep timing or signaling.

Evidence51

GABA may offer some calming support, but its direct role in better sleep remains uncertain.
Evidence strength
GABA may offer some calming support, though its direct contribution to better sleep remains uncertain.
Studied preparation
The label names GABA but no special preparation, so its possible sleep role remains general.

Formulation logic100

GABA can contribute on its own here; the small B6 amount doesn't add a second meaningful sleep role.
Partner coverage
GABA is treated as able to contribute on its own; no partner is required.
Conflicts
No listed ingredient is identified as working against sleep.
Effective doses
GABA has a stated 500 mg amount; the 2 mg B6 serving is too small to add a separate role.
Study evidence
GABA Supportive 4 studies
Stress Relief
Impact
Highest effect
A+ Ingredient FitC PathwaysA EvidenceA+ Formulation Logic
GABA · 500 mgVitamin B6 · 2 mg

GABA may help with short-term responses to stressful tasks. The supplied findings come from small, narrow settings and food preparations, so sustained everyday relief from a supplement remains uncertain. The declared serving reaches the comparison amount, but a larger quantity does not establish a stronger or more lasting effect.

How this product is rated for Stress Relief

Ingredient fit96

The declared relevant ingredients are focused on stress-related uses, with no unrelated actives reducing that focus. The counted amounts reach the comparison anchors; larger amounts do not establish stronger or more lasting relief.
Goal fit
The declared relevant ingredients are focused on stress-related uses, with no unrelated actives reducing that focus.
Dose adequacy
The counted amounts reach the comparison anchors; larger amounts do not establish stronger or more lasting relief.

Pathways60

The clearest contribution concerns neural calming. Other processes are represented to differing degrees by this serving.
Depth
The strongest supplied finding concerns neural calming, without proving a lasting clinical effect.
Breadth
The broader findings chiefly cover neural calming.

Evidence91

GABA leads the counted evidence. Recognized preparations are present, with benefit limited by the study contexts described above.
Evidence strength
GABA supplies the strongest counted evidence; its specific study limitations still govern expectations for relief.
Studied preparation
The counted preparations match those recognized by the supplied comparison, without establishing that all studies or populations match this product.

Formulation logic100

The counted ingredients have their relevant partners or stand alone, and no configured conflict was found. Their amounts reach the minimum comparison benchmark.
Partner coverage
The counted ingredients either work independently in this comparison or have their relevant partner present.
Conflicts
No configured ingredient conflict was found in the supplied findings.
Effective doses
All counted ingredients meet the minimum amount benchmark; this is not a proven effective dose for lasting stress relief.
Study evidence
GABA Supportive 6 studies

Ingredients

IngredientAmount per servingScore
Vitamin B6 (Pyridoxine Hydrochloride)
2 mg
GABA
500 mg 85
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
GABA · 500 mg OverallScore85
B- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value
The serving provides 500 mg of GABA. The whole-product serving costs about $0.09, a low price for the assessed GABA source.
How this ingredient is rated

Active Ingredient Quality & Bioavailability70

The saved information identifies generic GABA, while its production method is unresolved.
GABA Source & Production Method
The saved information identifies generic GABA, while its production method is unresolved.

Dose, Safety & Label Transparency93

The serving provides 500 mg of GABA. The saved ingredient information includes a flow agent.
GABA Dosage Adequacy & Transparency
The serving provides 500 mg of GABA.
Label Purity & Excipient Quality
The saved ingredient information includes a flow agent.

Value100

A whole-product serving costs about $0.09, a low serving price for the assessed GABA source.
Price per Effective Dose
A whole-product serving costs about $0.09, a low serving price for the assessed GABA source.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks.
    Yoto A; Murao S; Motoki M; Yokoyama Y; Horie N; Takeshima K; Masuda K; Kim M; Yokogoshi H · Amino acids · 2012
    Randomized trial63 participantsMood Support Stress Relief forGABA
  2. Peripartum neuroactive steroid and γ-aminobutyric acid profiles in women at-risk for postpartum depression.
    Deligiannidis KM; Kroll-Desrosiers AR; Mo S; Nguyen HP; Svenson A; Jaitly N; Hall JE; Barton BA; Rothschild AJ; Shaffer SA · Psychoneuroendocrinology · 2017
    Cohort study56 participantsMood Support forGABA
  3. The role of neurotransmitters in mediating the relationship between brain alterations and depressive symptoms in patients with inflammatory bowel disease.
    Wang J; Liu G; Xu K; Ai K; Huang W; Zhang J · Human brain mapping · 2023
    Case-control study69 participantsMood Support forGABA
  4. Occipital gamma-aminobutyric acid and glutamate-glutamine alterations in major depressive disorder: An mrs study and meta-analysis.
    Truong V; Cheng PZ; Lee HC; Lane TJ; Hsu TY; Duncan NW · Psychiatry research. Neuroimaging · 2021
    Observational studyMood Support forGABA
  5. Systematic review of gamma-aminobutyric-acid inhibitory deficits across the reproductive life cycle.
    Vigod SN; Strasburg K; Daskalakis ZJ; Blumberger DM · Archives of women's mental health · 2014
    Systematic review11 studies pooledMood Support forGABA
  6. High Dose Vitamin B6 Reduces Depression Symptoms.
    Field DT; Cracknell R; Biagi N · Depression and anxiety · 2026
    Randomized trial267 participantsMood Support forVitamin B6
  7. Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
    Khodadad M; Bahadoran P; Kheirabadi GR; Sabzghabaee AM · International journal of preventive medicine · 2022
    Randomized trial81 participantsMood Support Stress Relief forVitamin B6
  8. Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
    Lu J; Mao H; Tan Y; Luo G · Brain and behavior · 2024
    Cross-sectional study24,683 participantsMood Support forVitamin B6
  9. Associations of dietary B vitamins intakes with depression in adults.
    Wu Y; Li S; Wang W; Zhang D · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2023
    Observational study17,732 participantsMood Support forVitamin B6
  10. Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
    Shor-Posner G; Feaster D; Blaney NT; Rocca H; Mantero-Atienza E; Szapocznik J; Eisdorfer C; Goodkin K; Baum MK · International journal of psychiatry in medicine · 1995
    Cohort study88 participantsMood Support forVitamin B6
  11. Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial.
    Byun JI; Shin YY; Chung SE; Shin WC · Journal of clinical neurology (Seoul, Korea) · 2020
    Randomized trial40 participantsSleep Support forGABA
  12. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.
    Imafuku F; Yamamoto K; Tanaka E; Aoki R; Nishino S · Nutrients · 2023
    Randomized trial160 participantsSleep Support forGABA
  13. Reduced γ-aminobutyric acid in occipital and anterior cingulate cortices in primary insomnia: a link to major depressive disorder?
    Plante DT; Jensen JE; Schoerning L; Winkelman JW · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Case-control study40 participantsSleep Support forGABA
  14. GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial.
    Guimarães AP; Seidel H; Pires LVM; Trindade CO; Baleeiro RDS; Souza PM; Silva FGDE; Coelho DB; Becker LK; Oliveira EC · Journal of dietary supplements · 2024
    Randomized trial30 participantsSleep Support Stress Relief forGABA
  15. Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
    Zandifar A; Mousavi S; Schmidt NB; Badrfam R; Seif E; Qorbani M; Mehrabani Natanzi M · Journal of affective disorders · 2023
    Randomized trial66 participantsSleep Support forVitamin B6
  16. Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
    Jadidi A; Rezaei Ashtiani A; Khanmohamadi Hezaveh A; Aghaepour SM · BMC complementary medicine and therapies · 2023
    Randomized trial75 participantsSleep Support forVitamin B6
  17. Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
    García-García C; Baik I · Nutrition research and practice · 2022
    Randomized trial47 participantsSleep Support forVitamin B6
  18. Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
    Adventure-Heart DJ; Madden NA; Delfabbro P · Perceptual and motor skills · 2018
    Randomized trial100 participantsSleep Support forVitamin B6
  19. The effect of pyridoxine administration on melatonin secretion in normal men.
    Luboshitzky R; Ophir U; Nave R; Epstein R; Shen-Orr Z; Herer P · Neuro endocrinology letters · 2003
    Randomized trial12 participantsSleep Support forVitamin B6
  20. Relieving occupational fatigue by consumption of a beverage containing γ-amino butyric acid.
    Kanehira T; Nakamura Y; Nakamura K; Horie K; Horie N; Furugori K; Sauchi Y; Yokogoshi H · Journal of nutritional science and vitaminology · 2011
    Clinical trial30 participantsStress Relief forGABA