$52.70 $0.52 per serving
Product analysis
ACES supports normal immune function and collagen formation, especially when dietary intake is low. It is relatively costly for its vitamin C and selenium amounts.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality48
Selenium uses a favorable form, while quality remains uncertain for several other nutrients. Missing proportions in the calcium mix limit how precisely that part can be compared.
Ingredient Transparency67
Declared amounts and the main vitamin and mineral forms are stated. Some precise forms and the proportions in the calcium mix are missing.
Value For Money30
The vitamin C and selenium contributions are relatively costly. Value for several other nutrients remains uncertain, so they do not resolve the cost trade-off.
Customer Satisfaction85
Customer feedback is very positive across many ratings. Those opinions do not establish immune protection or cosmetic benefits.
Product Focus79
The clearest role is supporting normal immune and collagen functions when nutrient intake is low. The combination does not establish added skin, eye or nail improvements when nutritional needs are already met.
- Format
Softgel - Container
- 200 Softgel(s)
- Per serving
- $0.52
- Also available
ACES$25.42- Customer rating
- 4.8 · 1,422 ratings
Goals
Impact
Highest effect
Vitamin C · 1000 mgVitamin A · 3000 mcg RAESelenium · 100 mcg
Vitamin C contributes to normal immune-cell function and has limited regular-use support for modestly shorter colds. Vitamin A contributes to normal immune function and barriers, while selenium contributes to normal immune and antioxidant functions when intake is low. Vitamin E received a saved contribution, but mixed older-adult findings do not establish routine respiratory benefit in replete adults. These roles do not establish infection prevention.
How this product is rated for Immunity
Ingredient fit88
Relevant ingredients contribute to the immune goal, while additional actives make the formula less focused on these functions.
Goal fit
Relevant ingredients contribute to the immune goal, while additional actives make the formula less focused on these functions.
Dose adequacy
The counted amounts reach the saved comparison endpoints, without establishing added benefit from higher exposure.
Pathways100
The strongest represented area is the activity of first-response immune cells. The saved findings span several distinct immune functions, rather than concentrating on a single area.
Depth
The strongest represented area is the activity of first-response immune cells.
Breadth
The saved findings span several distinct immune functions, rather than concentrating on a single area.
Evidence100
Vitamin C leads the saved evidence finding, with bounded regular-use cold-duration evidence rather than proven infection prevention.
Evidence strength
Vitamin C leads the saved evidence finding, with bounded regular-use cold-duration evidence rather than proven infection prevention.
Studied preparation
The counted preparations match the saved preparation finding; this does not establish superior benefit from particular forms or delivery.
Formulation logic100
The counted ingredients have their relevant partners or contribute independently, and no listed formulation conflict was triggered.
Partner coverage
The counted ingredients can contribute independently or have their relevant partners; an extra combined benefit is not established.
Conflicts
No listed formulation conflict was triggered; this does not establish safety of the whole product.
Effective doses
The counted ingredients reach the saved minimum amount comparison, which is not a proven clinical benefit threshold.
Impact
Highest effect
Vitamin C · 1000 mgSelenium · 100 mcgVitamin E · 268 mg
Vitamin C supports normal collagen formation and can restore impaired wound healing caused by low intake. Its presence does not establish added cosmetic benefit when intake is adequate. Vitamin E and selenium have antioxidant roles, but those roles do not establish routine oral skin improvement. The C/E combination does not match the supplied high-dose UV studies or establish sunscreen-like protection.
How this product is rated for Skin Health
Ingredient fit88
The relevant ingredients provide a mixed skin-health connection. Declared amounts meet the saved exposure references.
Goal fit
Broader product aims or ingredients outside the credited skin-health roles reduce specific focus.
Dose adequacy
Declared amounts meet the exposure references without proving a cosmetic benefit or greater benefit from higher amounts.
Pathways80
The strongest saved connection concerns uv antioxidant defence. Two assessed pathways reach the breadth threshold.
Depth
The strongest saved connection concerns uv antioxidant defence, without proving an improvement in that skin outcome.
Breadth
Two assessed pathways reach the saved breadth threshold.
Evidence100
Vitamin C leads the saved evidence contribution. The preparation check is satisfied for included ingredients, without establishing routine cosmetic improvement.
Evidence strength
Vitamin C supplies the leading contribution, subject to its specific outcome and population limits.
Studied preparation
Included ingredients satisfy the saved preparation check; this does not prove efficacy of the finished product.
Formulation logic100
No required partner is missing and no configured conflict was matched. Included ingredients clear the minimum amount comparison.
Partner coverage
No required partner is missing from the included contributions.
Conflicts
No configured ingredient conflict was matched.
Effective doses
Included ingredients clear the minimum amount comparison; this is distinct from a proven skin-treatment dose.
Impact
Highest effect
Vitamin E · 268 mgVitamin C · 1000 mg
Vitamin C has antioxidant functions; a large trial was null overall, with CRP improvement confined to people starting with elevated CRP. Selenium supports antioxidant enzymes, but this does not establish added anti-inflammatory benefit above adequate intake.
How this product is rated for Inflammation
Ingredient fit83
Relevant ingredients form part of a broader formula with other actives. Retained quantities reach the comparison anchors; those anchors do not establish a proven effective dose for clinical inflammation relief.
Goal fit
Relevant ingredients form part of a broader formula with other actives.
Dose adequacy
Retained quantities reach the comparison anchors; those anchors do not establish a proven effective dose for clinical inflammation relief.
Pathways60
Oxidative and mitochondrial stress is the strongest recorded area; biological coverage does not itself establish symptom improvement.
Depth
Oxidative and mitochondrial stress is the strongest recorded area; biological coverage does not itself establish symptom improvement.
Breadth
Only oxidative and mitochondrial stress reached the coverage threshold.
Evidence96
Vitamin E leads the eligible evidence findings, while the clinical context limits expectations of general anti-inflammatory benefit.
Evidence strength
Vitamin E leads the eligible evidence findings, while the clinical context limits expectations of general anti-inflammatory benefit.
Studied preparation
Eligible preparations match the supplied comparison findings; this does not establish clinical benefit beyond the reviewed populations and outcomes.
Formulation logic100
No configured ingredient conflict was found. All retained ingredients meet the minimum comparison threshold; this threshold is not a proven effective dose for clinical anti-inflammatory relief.
Partner coverage
The retained ingredients have no unmet partner requirement in the supplied findings.
Conflicts
No configured ingredient conflict was found.
Effective doses
All retained ingredients meet the minimum comparison threshold; this threshold is not a proven effective dose for clinical anti-inflammatory relief.
Impact
High effect
Vitamin E · 268 mgVitamin C · 1000 mgVitamin A · 3000 mcg RAE
Vitamin A supports the visual cycle and dark adaptation when intake is low. Vitamins C and E contribute antioxidant functions, but their eye evidence concerns defined combinations in selected AMD populations rather than improved everyday vision. Selenium has no demonstrated cataract-prevention benefit. The substantial vitamin A amount per serving does not establish extra benefit beyond adequate intake.
How this product is rated for Eye Health
Ingredient fit88
The four vitamins and minerals dominate this formula, with their declared amounts fully represented in the saved findings.
Goal fit
Vitamin A, C, E and selenium dominate the formula, with calcium adding little vision focus.
Dose adequacy
The declared amounts fully meet the saved amount references; that does not establish additional visual benefit at higher intakes.
Pathways60
The saved findings concentrate on retinal and lens antioxidant defense, without macular-pigment or focusing support.
Depth
Retinal and lens antioxidant defense is the strongest saved area, driven by the counted antioxidant nutrients.
Breadth
Only antioxidant defense reaches the saved coverage criterion, leaving the formula’s vision coverage narrow.
Evidence74
Vitamin E leads the saved evidence finding, although its clinical evidence does not establish routine vision improvement.
Evidence strength
Vitamin E leads this saved finding, but combination-trial evidence does not establish its standalone routine vision benefit.
Studied preparation
The saved finding recognizes the counted preparations; matching a preparation does not remove the population and outcome limits of its evidence.
Formulation logic100
All four counted ingredients meet the saved amount criteria, with no missing partner or matched conflict.
Partner coverage
No required partner was missing among the counted ingredients; this does not establish extra benefit from combining them.
Conflicts
No configured ingredient conflict was matched in the supplied findings.
Effective doses
All counted ingredients meet the saved minimum amount criterion; this is not proof of a clinically effective vision dose.
Impact
Highest effect
Selenium · 100 mcgVitamin C · 1000 mg
Vitamin C and Selenium provide nutrients involved in normal antioxidant or immune functions. These nutritional contributions matter most when intake falls short; extra benefit with adequate intake is not established.
How this product is rated for Everyday Health
Ingredient fit93
The main relevant ingredients are Vitamin C and Selenium. Their value is nutritional, rather than a demonstrated broad health improvement.
Goal fit
Vitamin C and Selenium form the main nutritional contribution.
Dose adequacy
The selected serving provides a meaningful amount of Vitamin C and Selenium.
Pathways60
The main areas represented are antioxidant and immune defence.
Depth
The strongest supported area is antioxidant and immune defence, through the relevant nutrients.
Breadth
The main areas represented are antioxidant and immune defence.
Evidence82
Selenium supports a nutritional role, chiefly when intake is low; this does not establish extra benefit with adequate intake.
Evidence strength
Selenium supports a nutritional role, chiefly when intake is low; this does not establish extra benefit with adequate intake.
Studied preparation
The relevant nutrient preparations were accepted in the saved comparison; no superior form or delivery benefit is established.
Formulation logic100
The relevant ingredients can contribute independently or have their required partner; their combination does not establish added benefit. No conflict was identified by the evaluated checks.
Partner coverage
The relevant ingredients can contribute independently or have their required partner; their combination does not establish added benefit.
Conflicts
No conflict was identified by the evaluated checks.
Effective doses
The counted ingredients reach the comparison’s minimum amount criterion; this is not proof of a clinical benefit.
Impact
High effect
Vitamin C is needed for collagen synthesis, which provides a nutritional connection to nail structure. That requirement does not establish improved nail growth or reduced brittleness from supplementation when intake is adequate. The supplied evidence does not isolate a nail benefit from this vitamin combination, so the declared amounts do not demonstrate a specific nail outcome.
How this product is rated for Nail Health
Ingredient fit87
Vitamin C provides the main connection to nail health. The included amounts meet the reference exposure comparisons; higher amounts do not establish greater nail benefit.
Goal fit
Vitamin C provides the main nail connection, within a formula also aimed at other goals.
Dose adequacy
The included amounts meet the reference exposure comparisons; higher amounts do not establish greater nail benefit.
Pathways90
The main mapped connection concerns nail matrix structure; the supplied evidence does not establish a definite nail improvement. The saved findings span two areas, without demonstrating that their benefits add together.
Depth
The main mapped connection concerns nail matrix structure; the supplied evidence does not establish a definite nail improvement.
Breadth
The saved findings span two areas, without demonstrating that their benefits add together.
Evidence65
Vitamin E leads the saved comparison, but antioxidant activity does not establish improved nail growth or brittleness.
Evidence strength
Vitamin E leads the saved comparison, but antioxidant activity does not establish improved nail growth or brittleness.
Studied preparation
Selenium lack a confirmed match to the studied preparations, limiting transfer of nail outcomes.
Formulation logic100
No missing required partner or configured conflict was identified. The included amounts meet the minimum exposure comparison.
Partner coverage
No missing required partner was identified; combining the ingredients does not establish an added nail benefit.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
The included ingredients meet the minimum exposure comparison; this is not proof of an effective nail dose.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Calories | 15 Calorie(s) | |
Total Fat | 0.5 Gram(s) | |
Total Carbohydrates | 2 Gram(s) | |
Protein | 1 Gram(s) | |
Vitamin A (Beta-Carotene) | 3000 mcg RAE | |
Vitamin C (Calcium Ascorbate) | 1000 mg | |
Vitamin E (D-Alpha-Tocopherol) | 268 mg | |
Calcium (Calcium Ascorbate, Dicalcium Phosphate) | 110 mg | |
Selenium (L-Selenomethionine) | 100 mcg |
Selenium (L-Selenomethionine) · 100 mcg OverallScore77
Each serving provides 100 mcg of selenium as L-selenomethionine. L-selenomethionine is assessed as a readily absorbed selenium form.
How this ingredient is rated
Active Ingredient Quality & Bioavailability100
The selenium is supplied as L-selenomethionine.
Selenium Chemical Form
L-selenomethionine is assessed as a readily absorbed selenium form.
Form Transparency & Isomer Specificity
The saved facts identify the L form of selenomethionine.
Dose, Safety & Label Transparency88
The saved facts record 100 mcg of selenium per serving.
Dosage Efficacy Sweet Spot
The serving provides 100 mcg of selenium, a larger amount in this comparison.
Safety Margin & UL Adherence
The 100 mcg per serving is below the adult daily upper limit used in the evaluation; selenium from other sources adds to total intake.
Value10
The cost per amount of selenium is toward the higher end of the prices evaluated; it reflects the whole-product price.
Price per 200 mcg Serving
The whole-product price works out to about $1.05 per 200 mcg of selenium.
Vitamin C (Calcium Ascorbate) · 1000 mg OverallScore73
A serving provides 1,000 mg of vitamin C as buffered calcium ascorbate. The whole product costs about $0.53 per gram of vitamin C.
How this ingredient is rated
Active Ingredient Quality & Bioavailability83
The vitamin C comes from calcium ascorbate, a buffered mineral form.
Vitamin C Chemical Form & Delivery System
The vitamin C form is calcium ascorbate.
Gastric Comfort & pH Balance
Calcium Ascorbate is a buffered mineral form.
Dose, Safety & Label Transparency91
A serving provides 1,000 mg of vitamin C.
Optimal Dosage Targeting
A serving provides 1,000 mg of vitamin C.
Purity & Excipient Quality
No evaluated artificial colors, preservatives or sweetening ingredients are recorded.
Mineral & Source Transparency
Vitamin C and product calcium amounts are recorded; not all of the calcium necessarily comes from calcium ascorbate.
Value20
The whole product costs about $0.53 per gram of vitamin C.
Price per Gram of Vitamin C
The whole product costs about $0.53 per gram of vitamin C.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
- Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
- The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
- Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
- Updates on clinical studies of selenium supplementation in radiotherapy.
- Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
- Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
- Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
- Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
- Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension trial.
- AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
- The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
- A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa.
- Efficacy and safety of retinol palmitate ophthalmic solution in the treatment of dry eye: a Japanese Phase II clinical trial.
- Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age.
- Vitamin A supplementation improves retinal function in infants at risk of retinopathy of prematurity.
- Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathy.
- Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.