Ubiquinol

Ubiquinol

Dr. Mercola4.8 (83 ratings)
Format:Liquid Quantity: 1 Liquid(s) · 18 servings
Goals
$22.99 $1.27 per serving

Product analysis

44 out of 100

Ubiquinol may support blood-vessel function in selected adults, with more limited evidence for routine energy benefits. The serving is relatively expensive compared with other CoQ10 options.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The CoQ10 ingredient lacks a clear form declaration for a close quality comparison. That leaves its form quality uncertain.

Ingredient Transparency63

The CoQ10 amount is disclosed, allowing serving quantities to be compared. Its ingredient declaration does not clearly specify the form, limiting a closer comparison.

Value For Money20

The serving is relatively expensive compared with other CoQ10 supplements. The available form details do not establish an absorption advantage that explains the higher cost.

Customer Satisfaction73

Customers give very positive ratings. The small review base makes the satisfaction picture less settled.

Product Focus73

The single-ingredient formula is most relevant to selected blood-vessel-function findings. Its role in cellular energy production does not establish a dependable energy boost for healthy adults.

Format
Liquid
Container
1 Liquid(s)
Per serving
$1.27
Customer rating
4.8 · 83 ratings
Report analysis

Goals

Longevity
Impact
Moderate effect
B- Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Ubiquinol is a form of CoQ10 involved in mitochondrial energy and antioxidant processes. At 100 mg it has a functional connection to healthy aging, but the supplied skin-aging findings concern a different identified preparation; greater absorption does not establish equivalent clinical benefits.

How this product is rated for Longevity

Ingredient fit73

The relevant ingredients are a clear focus of the formula. The assessed amounts partly meet the saved comparison benchmarks.
Goal fit
The relevant ingredients are a clear focus of the formula.
Dose adequacy
The assessed amounts partly meet the saved comparison benchmarks.

Pathways10

The strongest assessed area is mitochondrial energy production, with limited coverage. No assessed area reaches the threshold for substantial coverage.
Depth
The strongest assessed area is mitochondrial energy production, with limited coverage.
Breadth
No assessed area reaches the threshold for substantial coverage.

Evidence30

Coenzyme Q-10 provides the strongest evidence contribution among the assessed ingredients, with important limits on broader healthy-aging claims. The assessed ingredients do not match the recognized trial preparations.
Evidence strength
Coenzyme Q-10 provides the strongest evidence contribution among the assessed ingredients, with important limits on broader healthy-aging claims.
Studied preparation
The assessed ingredients do not match the recognized trial preparations.

Formulation logic100

The assessed ingredients can contribute independently or have their required partner. No configured ingredient conflict was matched in the supplied assessment. All ingredients included in this check reach its minimum amount threshold.
Partner coverage
The assessed ingredients can contribute independently or have their required partner.
Conflicts
No configured ingredient conflict was matched in the supplied assessment.
Effective doses
All ingredients included in this check reach its minimum amount threshold.
Study evidence
Heart Health
Impact
Highest effect
A Ingredient FitC PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

CoQ10 has limited evidence concerning vascular function, blood pressure and lipids from small trials in selected adults. The declared active amount contributes to the saved comparison. These findings concern intermediate measures and do not establish routine prevention of cardiovascular events or superiority of one delivery form. Generic naming does not identify oxidation state.

How this product is rated for Heart Health

Ingredient fit93

CoQ10 is the focused ingredient, with a declared amount contributing to the saved comparison.
Goal fit
CoQ10 supplies the counted contribution without unrelated actives diluting it.
Dose adequacy
The counted amount reaches the full saved comparison, without establishing an optimal clinical dose.

Pathways60

The saved contribution is concentrated in vascular lining function.
Depth
Vascular lining function is the strongest tracked area.
Breadth
Only vascular lining function reaches the breadth comparison.

Evidence98

CoQ10 has limited selected-population evidence for vascular, blood-pressure and lipid measures, without establishing routine cardiovascular-event prevention.
Evidence strength
CoQ10 has limited selected-population evidence for vascular, blood-pressure and lipid measures, without establishing routine cardiovascular-event prevention.
Studied preparation
The saved findings accept the counted preparations, without demonstrating special benefits from their forms.

Formulation logic100

The counted ingredients need no additional partner for their saved contributions. No configured ingredient conflict was matched.
Partner coverage
The counted ingredients work alone or have the required partner in the saved findings.
Conflicts
No configured ingredient conflict was matched.
Effective doses
All counted ingredients reach the saved minimum amount comparison.
Study evidence
Energy
Impact
High effect
B- Ingredient FitD- PathwaysA+ EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

CoQ10 supports cellular energy production, with limited evidence for fatigue relief that depends on the preparation and population studied. Clinical-cohort findings do not establish routine energy benefits in healthy adults. Its included serving receives amount support, without proving an absorption advantage or a guaranteed response.

How this product is rated for Energy

Ingredient fit73

The relevant included ingredients are Coenzyme Q-10. Their amounts receive different levels of support in the supplied findings.
Goal fit
The relevant ingredients dominate the assessed formulation, although the product is also linked to other goals.
Dose adequacy
The included amounts provide partial support against the saved amount references, without defining proven fatigue-treatment doses.

Pathways40

The supplied findings concentrate on cellular energy production. They do not establish broad coverage across the other configured energy pathways.
Depth
The best-represented configured pathway is cellular energy production.
Breadth
Only cellular energy production reaches the saved breadth requirement; other configured pathways do not.

Evidence95

The strongest included evidence contribution comes from Coenzyme Q-10. Preparation matching does not remove the ingredient-specific limits on fatigue benefits.
Evidence strength
Coenzyme Q-10 provides the strongest included evidence contribution, subject to its specific population and deficiency limitations.
Studied preparation
The included preparations meet the saved study check, without establishing that the finished product itself was tested.

Formulation logic100

The counted ingredients meet the minimum amount requirement, without a missing required partner or matched conflict.
Partner coverage
No included ingredient lacks a required partner in the supplied findings; this does not imply extra benefit from combining ingredients.
Conflicts
No configured ingredient conflict was matched in the supplied facts.
Effective doses
All counted ingredients meet the saved minimum amount requirement, which is distinct from a proven fatigue-treatment dose.
Study evidence
Cardiovascular Support
Impact
Highest effect
A Ingredient FitC PathwaysA- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Ubiquinol may support the function of the lining of blood vessels. The serving's 100 mg of explicitly identified active ubiquinol matches the comparison anchor from a small trial in adults with abnormal blood lipids and impaired vessel function. That context limits generalization. The supplied findings do not establish cardiovascular-event prevention, greater benefit at higher amounts, or superiority over other CoQ10 forms.

How this product is rated for Cardiovascular Support

Ingredient fit93

Ubiquinol is the sole contributing active. The 100 mg ubiquinol serving meets its preparation-specific quantity reference.
Goal fit
Ubiquinol is the sole contributing active.
Dose adequacy
The 100 mg ubiquinol serving meets its preparation-specific quantity reference.

Pathways60

The supplied findings concentrate on the function of the blood-vessel lining. Other cardiovascular aspects are not broadly represented.
Depth
The function of the blood-vessel lining is the strongest represented aspect in the supplied findings.
Breadth
Only the function of the blood-vessel lining reaches the coverage threshold, so the contribution has limited breadth.

Evidence88

CoQ10 has support for selected vascular and lipid markers in adults with abnormal blood lipids.
Evidence strength
CoQ10 has support for selected vascular and lipid markers in adults with abnormal blood lipids.
Studied preparation
The declared Ubiquinol preparation is accepted in the supplied comparison, without establishing superiority over other forms.

Formulation logic100

The retained ingredient can contribute without a required additional partner. No checked conflict was matched, and the contributing amounts reach the inclusion threshold.
Partner coverage
Ubiquinol does not require an additional ingredient partner for the contribution retained here.
Conflicts
None of the specific ingredient conflicts checked in the supplied comparison was matched.
Effective doses
Ubiquinol reaches the comparison's amount threshold for inclusion; this is not a proven effective-dose boundary.
Study evidence
Metabolism Support
Impact
High effect
B- Ingredient FitF PathwaysB- EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

Coenzyme Q10 participates in mitochondrial energy transfer. That normal role and changes in metabolic biomarkers do not establish that supplementation makes the body burn more energy. The supplied findings do not demonstrate a routine rise in whole-body energy expenditure or a special metabolic advantage for the declared form.

How this product is rated for Metabolism Support

Ingredient fit73

The relevant ingredients are the focus of the supplied formula, with amounts recognized to varying extents in the saved comparison.
Goal fit
The supplied formula centers on ingredients considered for this goal, without additional off-goal actives.
Dose adequacy
The declared amounts provide partial or uneven coverage of the saved comparison ranges, rather than demonstrating a measured metabolic-rate response.

Pathways17

The strongest represented route is mitochondrial energy and fat oxidation, with limited coverage; this does not establish measured thermogenesis. No route reaches the breadth threshold.
Depth
The strongest represented route is mitochondrial energy and fat oxidation, with limited coverage; this does not establish measured thermogenesis.
Breadth
No route reaches the saved coverage threshold.

Evidence75

Coenzyme Q10 receives consideration, but mitochondrial and biomarker findings do not demonstrate increased whole-body energy expenditure.
Evidence strength
The saved findings give Coenzyme Q-10 the leading contribution, while its supplied scientific context limits claims about a routine rise in energy expenditure.
Studied preparation
The counted ingredients receive preparation recognition; this does not establish that this finished formula was tested for increased energy expenditure.

Formulation logic100

The counted ingredients pass the saved amount threshold, with no missing required partners or triggered conflicts. This does not establish a thermogenic effect from the combination.
Partner coverage
No required partner is missing for the counted ingredients; the finding does not establish additional benefit from their combination.
Conflicts
No configured ingredient conflict is triggered by the supplied facts; this does not establish complete interaction coverage or individual suitability.
Effective doses
All counted ingredients pass the saved amount threshold; passing it does not prove a thermogenic effect.
Study evidence
Inflammation
Impact
Moderate effect
B- Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Coenzyme Q-10 · 100 mg

CoQ10 at 100 mg is supplied as ubiquinol, its reduced form. Its relevance is mainly to oxidative and mitochondrial stress; the supplied human evidence is limited to selected inflammatory markers in a specific clinical setting, so routine inflammation relief remains uncertain.

How this product is rated for Inflammation

Ingredient fit73

The relevant ingredients give a focused contribution to the goal. The relevant amounts provide a partial match to the supplied dose comparisons.
Goal fit
The relevant ingredients give a focused contribution to the goal.
Dose adequacy
The relevant amounts provide a partial match to the supplied dose comparisons.

Pathways19

Oxidative and mitochondrial stress is the main area of support, with limited coverage in the saved findings. The saved findings show limited reach across the different aspects of inflammation support.
Depth
Oxidative and mitochondrial stress is the main area of support, with limited coverage in the saved findings.
Breadth
The saved findings show limited reach across the different aspects of inflammation support.

Evidence63

Coenzyme Q-10 provides the strongest relevant human evidence at the assessed amount, although practical benefits depend on context. The assessed preparation was not matched to the preparation used in the supplied human evidence.
Evidence strength
Coenzyme Q-10 provides the strongest relevant human evidence at the assessed amount, although practical benefits depend on context.
Studied preparation
The assessed preparation was not matched to the preparation used in the supplied human evidence.

Formulation logic100

The assessed ingredients can contribute on their own or have their required partner present. No ingredient conflicts were identified in the saved assessment. All assessed ingredients met the saved minimum amount criterion.
Partner coverage
The assessed ingredients can contribute on their own or have their required partner present.
Conflicts
No ingredient conflicts were identified in the saved assessment.
Effective doses
All assessed ingredients met the saved minimum amount criterion.
Study evidence

Ingredients

IngredientAmount per servingScore
Kaneka Ubiquinol
100 mg 73
Adults 18–50
Report overview
Coenzyme Q-10 · 100 mg OverallScore73
B- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
A serving lists 100 mg of CoQ10 as ubiquinol. The whole-product serving costs about $1.28.
How this ingredient is rated

Active Ingredient Quality & Bioavailability72

The saved facts identify the CoQ10 form as ubiquinol.
Molecular Form: Ubiquinol vs. Ubiquinone
The CoQ10 is identified as ubiquinol.
Formulation & Absorption Enhancers
The saved facts do not establish a named absorption-enhancing formulation or black pepper extract.

Dose, Safety & Label Transparency100

The label lists 100 mg CoQ10 per serving.
Clinical Dosage Alignment
The serving lists 100 mg CoQ10 as ubiquinol.
Label Transparency & Fillers
The label lists 100 mg CoQ10 per serving; no flagged additives or standard fillers are recorded in the evaluated facts.

Value20

A whole-product serving costs about $1.28.
Price Per Effective Serving
At about $1.28 per whole-product serving, the price is high in this comparison.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
    Liu Z; Tian Z; Zhao D; Liang Y; Dai S; Liu M; Hou S; Dong X; Zhaxinima; Yang Y · The Journal of clinical endocrinology and metabolism · 2022
    Meta-analysis2,794 participants50 studies pooledCardiovascular Support Heart Health forCoenzyme Q-10
  2. Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: a randomized double-blind, placebo-controlled trial.
    Vrentzos E; Ikonomidis I; Pavlidis G; Katogiannis K; Korakas E; Kountouri A; Pliouta L; Michalopoulou E; Pelekanou E; Boumpas D; Lambadiari V · Cardiovascular diabetology · 2024
    Randomized trial60 participantsCardiovascular Support forCoenzyme Q-10
  3. The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
    Mortensen SA; Rosenfeldt F; Kumar A; Dolliner P; Filipiak KJ; Pella D; Alehagen U; Steurer G; Littarru GP; Q-SYMBIO Study Investigators · JACC. Heart failure · 2015
    Randomized trial420 participantsCardiovascular Support forCoenzyme Q-10
  4. [Coenzyme Q-10 in the treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: systematic review and meta-analysis].
    Mareev VY; Mareev YV; Begrambekova YL · Kardiologiia · 2022
    Meta-analysis1,139 participants6 studies pooledCardiovascular Support forCoenzyme Q-10
  5. Effect of coenzyme Q10 in Europeans with chronic heart failure: A sub-group analysis of the Q-SYMBIO randomized double-blind trial.
    Mortensen AL; Rosenfeldt F; Filipiak KJ · Cardiology journal · 2020
    Randomized trialCardiovascular Support forCoenzyme Q-10
  6. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials.
    Qu H; Guo M; Chai H; Wang WT; Gao ZY; Shi DZ · Journal of the American Heart Association · 2019
    Meta-analysis575 participants12 studies pooledEnergy forCoenzyme Q-10
  7. Coenzyme Q10 Supplementation in Athletes: A Systematic Review.
    Fernandes MSS; Fidelis DEDS; Aidar FJ; Badicu G; Greco G; Cataldi S; Santos GCJ; de Souza RF; Ardigò LP · Nutrients · 2026
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  8. Effectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Tsai IC; Hsu CW; Chang CH; Tseng PT; Chang KV · Frontiers in pharmacology · 2024
    Meta-analysis1,126 participants13 studies pooledEnergy forCoenzyme Q-10
  9. Antifatigue effects of coenzyme Q10 during physical fatigue.
    Mizuno K; Tanaka M; Nozaki S; Mizuma H; Ataka S; Tahara T; Sugino T; Shirai T; Kajimoto Y; Kuratsune H; Kajimoto O; Watanabe Y · Nutrition (Burbank, Los Angeles County, Calif.) · 2008
    Randomized trial17 participantsEnergy forCoenzyme Q-10
  10. Effect of coenzyme Q10 supplementation on fatigue: A systematic review of interventional studies.
    Mehrabani S; Askari G; Miraghajani M; Tavakoly R; Arab A · Complementary therapies in medicine · 2019
    Systematic review16 studies pooledEnergy forCoenzyme Q-10
  11. Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial.
    Sabbatinelli J; Orlando P; Galeazzi R; Silvestri S; Cirilli I; Marcheggiani F; Dludla PV; Giuliani A; Bonfigli AR; Mazzanti L; Olivieri F; Antonicelli R; Tiano L · Nutrients · 2021
    Randomized trial51 participantsHeart Health forCoenzyme Q-10
  12. Dose-Response Effect of Coenzyme Q10 Supplementation on Blood Pressure among Patients with Cardiometabolic Disorders: A Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.
    Zhao D; Liang Y; Dai S; Hou S; Liu Z; Liu M; Dong X; Zhan Y; Tian Z; Yang Y · Advances in nutrition (Bethesda, Md.) · 2022
    Meta-analysis1,831 participants26 studies pooledHeart Health forCoenzyme Q-10
  13. Effects of Coenzyme Q10 on Lipid, Glycemic, and Inflammatory Markers in Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Zhang Z; Liu Z; Geng Y; Huang Y; Hu R; Li F; Song Y; Zhang M · Journal of diabetes research · 2026
    Meta-analysis3,422 participants64 studies pooledHeart Health Metabolism Support forCoenzyme Q-10
  14. Treatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individuals.
    Zhang P; Yang C; Guo H; Wang J; Lin S; Li H; Yang Y; Ling W · Journal of clinical lipidology · 2019
    Randomized trial101 participantsHeart Health forCoenzyme Q-10
  15. The effect of coenzyme Q10 supplementation on inflammatory and endothelial dysfunction markers in overweight/obese polycystic ovary syndrome patients.
    Taghizadeh S; Izadi A; Shirazi S; Parizad M; Pourghassem Gargari B · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2021
    Randomized trial43 participantsInflammation forCoenzyme Q-10
  16. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome.
    Karamali M; Gholizadeh M · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
    Randomized trial55 participantsInflammation forCoenzyme Q-10
  17. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation-Related Biomarkers: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.
    Hou S; Tian Z; Zhao D; Liang Y; Dai S; Ji Q; Fan Z; Liu Z; Liu M; Yang Y · Molecular nutrition & food research · 2023
    Meta-analysis1,517 participants31 studies pooledInflammation forCoenzyme Q-10
  18. Can coenzyme Q10 supplementation effectively reduce human tumor necrosis factor-α and interleukin-6 levels in chronic inflammatory diseases? A systematic review and meta-analysis of randomized controlled trials.
    Farsi F; Heshmati J; Keshtkar A; Irandoost P; Alamdari NM; Akbari A; Janani L; Morshedzadeh N; Vafa M · Pharmacological research · 2020
    Meta-analysis509 participants9 studies pooledInflammation forCoenzyme Q-10
  19. Promising efficacy of coenzyme Q10 supplementation as adjunctive therapy in juvenile idiopathic arthritis: a randomized-controlled pilot study.
    Elsherif N; Shousha G; Sabri NA; Shawki MA · Immunopharmacology and immunotoxicology · 2026
    Randomized trial58 participantsInflammation forCoenzyme Q-10
  20. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview.
    Mantle D; Hargreaves I · Antioxidants (Basel, Switzerland) · 2020
    Narrative reviewLongevity forCoenzyme Q-10