Acetyl L-Carnitine 500 mg

Acetyl L-Carnitine 500 mg

Nature's Way4.7 (13 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$16.64 $0.27 per serving

Product analysis

53 out of 100

Acetyl L-Carnitine 500 mg offers a focused ingredient involved in the body’s energy processes at a reasonably favorable cost. Improvements in everyday energy or thinking remain uncertain because the relevant findings concern specific clinical groups.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The ingredient preparation is unspecified, limiting a confident quality comparison. Results associated with another carnitine form cannot establish the quality of this preparation.

Ingredient Transparency63

The amount of acetyl L-carnitine is disclosed, helping compare servings. Its form is unspecified, leaving preparation details unclear.

Value For Money75

The declared acetyl L-carnitine amount offers reasonably favorable value. That cost comparison does not establish an effective amount for everyday cognitive or energy benefits.

Customer Satisfaction70

Customer ratings are very positive but come from very few reviews. The small review base limits confidence about wider customer experience.

Product Focus57

A single ingredient focuses on cellular energy processes. Those roles do not establish routine improvements in concentration, energy or work performance in healthy adults.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.27
Customer rating
4.7 · 13 ratings
Report analysis

Goals

Brain Health
Impact
High effect
B- Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Study evidence
Energy
Impact
High effect
B- Ingredient FitD- PathwaysA+ EvidenceA+ Formulation Logic
Acetyl L-Carnitine · 500 mg
Study evidence
Productivity Boost
Impact
Moderate effect
B- Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic
Acetyl L-Carnitine · 500 mgAcetyl L-Carnitine · 500 mg
Study evidence
Cognitive Support
Impact
High effect
B- Ingredient FitD- PathwaysB EvidenceA+ Formulation Logic
Acetyl L-Carnitine · 500 mg
Study evidence
Metabolism Support
Impact
Lower effect
B- Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Acetyl L-Carnitine · 500 mg
Study evidence
Mental Focus
Impact
High effect
B- Ingredient FitD- PathwaysB+ EvidenceA+ Formulation Logic
Acetyl L-Carnitine · 500 mg
Study evidence

Ingredients

IngredientAmount per servingScore
Acetyl L-Carnitine HCl
500 mg 90
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Report overview
Acetyl L-Carnitine · 500 mg OverallScore90
A- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB Value
Acetyl L-Carnitine 500 mg provides 500 mg of acetyl L-carnitine HCl per serving. The cost per 500 mg of acetyl L-carnitine is moderate. The HCl form is named.
How this ingredient is rated

Active Ingredient Quality & Bioavailability88

It contains acetyl L-carnitine HCl. No purity testing or good manufacturing practice claim is available.
ALCAR vs. Standard Carnitine Form
Acetyl L-carnitine is present.
Advanced Sourcing and Salt Specificity
The HCl form is named. No purity testing or good manufacturing practice claim is available.

Dose, Safety & Label Transparency100

500 mg per serving falls within the range described for cognitive and metabolic support. The amount is stated separately.
Clinical Dosage Efficacy
500 mg per serving falls within the range described for cognitive and metabolic support.
Label Transparency and Proprietary Blends
The acetyl L-carnitine amount is stated as 500 mg per serving.

Value75

The cost per 500 mg of acetyl L-carnitine is moderate.
Price per 500mg Acetyl L-Carnitine
The cost per 500 mg of acetyl L-carnitine is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acetyl-L-carnitine treatment in minimal hepatic encephalopathy.
    Malaguarnera M; Gargante MP; Cristaldi E; Vacante M; Risino C; Cammalleri L; Pennisi G; Rampello L · Digestive diseases and sciences · 2008
    Randomized trial125 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  2. Long-term acetyl-L-carnitine treatment in Alzheimer's disease.
    Spagnoli A; Lucca U; Menasce G; Bandera L; Cizza G; Forloni G; Tettamanti M; Frattura L; Tiraboschi P; Comelli M · Neurology · 1991
    Randomized trial130 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  3. Pharmaco-electroencephalographic and clinical effects of the cholinergic substance--acetyl-L-carnitine--in patients with organic brain syndrome.
    Herrmann WM; Dietrich B; Hiersemenzel R · International journal of clinical pharmacology research · 1990
    Randomized trialBrain Health forAcetyl L-Carnitine
  4. Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial.
    Malaguarnera M; Vacante M; Motta M; Giordano M; Malaguarnera G; Bella R; Nunnari G; Rampello L; Pennisi G · Metabolic brain disease · 2012
    Randomized trial61 participantsBrain Health Cognitive Support forAcetyl L-Carnitine
  5. Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
    Passeri M; Cucinotta D; Bonati PA; Iannuccelli M; Parnetti L; Senin U · International journal of clinical pharmacology research · 1990
    Randomized trial60 participantsBrain Health Mental Focus forAcetyl L-Carnitine
  6. A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys.
    Torrioli MG; Vernacotola S; Peruzzi L; Tabolacci E; Mila M; Militerni R; Musumeci S; Ramos FJ; Frontera M; Sorge G; Marzullo E; Romeo G; Vallee L; Veneselli E; Cocchi E; Garbarino E; Moscato U; Chiurazzi P; D'Iddio S; Calvani M; Neri G · American journal of medical genetics. Part A · 2008
    Randomized trial63 participantsCognitive Support forAcetyl L-Carnitine
  7. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue.
    Malaguarnera M; Gargante MP; Cristaldi E; Colonna V; Messano M; Koverech A; Neri S; Vacante M; Cammalleri L; Motta M · Archives of gerontology and geriatrics · 2008
    Randomized trial96 participantsCognitive Support forAcetyl L-Carnitine
  8. Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.
    Malaguarnera M; Vacante M; Giordano M; Pennisi G; Bella R; Rampello L; Malaguarnera M; Li Volti G; Galvano F · The American journal of clinical nutrition · 2011
    Randomized trial121 participantsEnergy forAcetyl L-Carnitine
  9. The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin.
    Malaguarnera M; Vacante M; Bertino G; Neri S; Malaguarnera M; Gargante MP; Motta M; Lupo L; Chisari G; Bruno CM; Pennisi G; Bella R · Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2012
    Randomized trial60 participantsEnergy forAcetyl L-Carnitine
  10. Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy.
    Malaguarnera M; Bella R; Vacante M; Giordano M; Malaguarnera G; Gargante MP; Motta M; Mistretta A; Rampello L; Pennisi G · Scandinavian journal of gastroenterology · 2011
    Randomized trial67 participantsEnergy forAcetyl L-Carnitine
  11. A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy.
    Sun Y; Shu Y; Liu B; Liu P; Wu C; Zheng R; Zhang X; Zhuang Z; Deng Y; Zheng L; Xu Q; Jiang B; Ouyang X; Gao J; Xu N; Li X; Jiang S; Liang C; Yao Y · Experimental and therapeutic medicine · 2020
    Randomized trial239 participantsEnergy forAcetyl L-Carnitine
  12. Metabolomic biomarkers for (R, S)-ketamine and (S)-ketamine in treatment-resistant depression and healthy controls: A systematic review.
    Kumar R; Nuñez NA; Joshi N; Joseph B; Verde A; Seshadri A; Cuellar Barboza AB; Prokop LJ; Medeiros GC; Singh B · Bipolar disorders · 2024
    Systematic reviewEnergy forAcetyl L-Carnitine
  13. Acetyl-L-carnitine Slows the Progression from Prefrailty to Frailty in Older Subjects: A Randomized Interventional Clinical Trial.
    Malaguarnera G; Catania VE; Bertino G; Chisari LM; Castorina M; Bonfiglio C; Cauli O; Malaguarnera M · Current pharmaceutical design · 2022
    Randomized trial92 participantsLongevity forAcetyl L-Carnitine
  14. Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial.
    Malaguarnera G; Pennisi M; Gagliano C; Vacante M; Malaguarnera M; Salomone S; Drago F; Bertino G; Caraci F; Nunnari G; Malaguarnera M · Hepatitis monthly · 2014
    Randomized trial62 participantsMental Focus Productivity Boost forAcetyl L-Carnitine
  15. [Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration].
    Lino A; Boccia MM; Rusconi AC; Bellomonte L; Cocuroccia B · La Clinica terapeutica · 1992
    Non-randomized trial17 participantsMental Focus forAcetyl L-Carnitine
  16. Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial.
    Arnold LE; Amato A; Bozzolo H; Hollway J; Cook A; Ramadan Y; Crowl L; Zhang D; Thompson S; Testa G; Kliewer V; Wigal T; McBurnett K; Manos M · Journal of child and adolescent psychopharmacology · 2008
    Randomized trial112 participantsMental Focus forAcetyl L-Carnitine
  17. Acetyl-L-carnitine for patients with hepatic encephalopathy.
    Martí-Carvajal AJ; Gluud C; Arevalo-Rodriguez I; Martí-Amarista CE · The Cochrane database of systematic reviews · 2019
    Meta-analysis398 participants5 studies pooledMental Focus forAcetyl L-Carnitine
  18. Low Bioavailability and High TMAO Production: Novel Insights Into Acetylcarnitine and Carnitine Metabolism.
    Krims-Davis K; Ozola M; Razzivina V; Gukalova B; Konrade I; Dambrova M; Liepinsh E · Molecular nutrition & food research · 2025
    Randomized trialMetabolism Support forAcetyl L-Carnitine