5-HTP with Vitamin B6 100 mg
Goals
$29.99 $0.24 per serving
Product analysis
5-HTP with Vitamin B6 100 mg is aimed at mood and relaxation, with possible sleep support in poor sleepers. The ingredients’ roles in brain signaling leave routine benefits from the combination uncertain.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality40
The ingredient sources are named, making the contents identifiable. Their relative preparation quality remains uncertain.
Ingredient Transparency100
Amounts and forms are clearly stated for the ingredients. The label makes comparisons of the declared contents straightforward.
Value For Money60
The 5-HTP content compares favorably for the cost. Value for the added vitamin and mineral portions remains uncertain.
Customer Satisfaction74
Customer ratings are very positive, but only a few ratings are available. The small review base gives a limited view of satisfaction.
Product Focus65
The formula targets related mood, relaxation and sleep uses through 5-HTP and B6. Support is conditional, and adding B6 does not establish an extra combined benefit.
- Format
Capsule - Container
- 120 Capsule(s)
- Per serving
- $0.24
- Customer rating
- 4.9 · 19 ratings
Goals
Impact
Highest effect
Vitamin B6 · 20 mg5-HTP · 100 mg
Vitamin B6 can help address deficiency associated with low mood or confusion, without establishing extra mood improvement when intake is adequate. 5-HTP is a serotonin precursor, but that mechanism does not establish a general mood benefit. The supplied mood findings leave routine benefit from this combination uncertain.
How this product is rated for Mood Support
Ingredient fit77
The ingredient selection and known amounts determine how closely this formula relates to mood. Its relevant roles remain subject to the specific nutritional or preparation limits described above.
Goal fit
The formula is relatively focused on mood-related ingredients, while its links to other goals broaden its intended use.
Dose adequacy
The relevant amounts provide a partial match to the saved reference ranges; these ranges do not establish proven effective exposures.
Pathways60
The represented biological areas describe the ingredients' connection to mood; their coverage does not establish a measured improvement in emotional well-being.
Depth
Monoamine signalling is the strongest represented area, without establishing a measured mood improvement.
Breadth
One biological areas meet the saved comparison's coverage level; this does not demonstrate multiple independent mood benefits.
Evidence96
The saved ingredient comparison and preparation findings must be read alongside the supplied limits on populations and direct mood outcomes.
Evidence strength
Vitamin B6 leads the saved evidence comparison, but the supplied population and outcome limits still govern expected mood benefits.
Studied preparation
The saved comparison accepts the forms with known qualifying amounts; this does not establish routine mood benefit for every ingredient.
Formulation logic100
No specified conflict or missing required partner was identified. The individual amount findings determine which ingredients can be meaningfully compared.
Partner coverage
No required ingredient partner is missing among the ingredients considered; this does not establish added benefit from combining them.
Conflicts
None of the specified ingredient conflicts was identified in the supplied facts.
Effective doses
All ingredients counted here meet the saved minimum amount criterion; that criterion is not proof of an effective mood dose.
Impact
Moderate effect
5-HTP may offer some support through the serotonin–melatonin precursor route, but the supplied context points to a limited role, mainly for poor sleepers. It doesn't establish a broad sleep benefit across adults.
Vitamin B6 supports normal neurotransmitter metabolism, but that role alone doesn't show that extra B6 improves sleep. The product's possible sleep contribution therefore rests mainly on 5-HTP.
How this product is rated for Sleep Support
Ingredient fit77
5-HTP supplies the clearest sleep link; B6 is included but doesn't establish an independent sleep benefit.
Goal fit
5-HTP is the main sleep-oriented ingredient; Calcium and Phosphorus have no described sleep role in these facts.
Dose adequacy
One serving lists 100 mg of 5-HTP and 20 mg of B6; the amounts are clear, though B6's amount doesn't establish extra sleep support.
Pathways60
The formula centers on precursor metabolism and does not cover separate timing or calming routes.
Depth
5-HTP provides the strongest route through serotonin–melatonin precursors; B6's normal metabolic role doesn't prove better sleep.
Breadth
The product's possible pathway contribution stays with precursors rather than covering several sleep processes.
Evidence58
5-HTP has a limited, context-specific possible role, while B6 does not add a separately established sleep benefit.
Evidence strength
5-HTP may help some poor sleepers, but the supplied context doesn't establish broad benefit for other adults.
Studied preparation
The 5-HTP and B6 forms are identified, but B6's normal metabolic role doesn't establish an independent sleep benefit.
Formulation logic100
Neither ingredient needs a partner for its described role, and the supplied ingredients show no configured sleep conflict.
Partner coverage
The possible 5-HTP contribution can stand alone; B6 isn't required as a sleep partner.
Conflicts
Neither 5-HTP nor B6 is a configured sleep conflict in the supplied ingredient list.
Effective doses
The 100 mg 5-HTP and 20 mg B6 amounts are recognized here, but neither amount proves that sleep will improve.
Impact
High effect
Vitamin B6 · 20 mg
5-HTP has some conditional findings in anxiety and stress-related settings, while vitamin B6 has limited direct anxiety evidence and stress findings often come from combinations. These ingredients connect mainly with mood and neurotransmitter-related processes, without establishing broad everyday calmness. The serving’s 20 mg B6 receives partial amount recognition. Adding B6 to 5-HTP does not establish an extra combined stress benefit.
How this product is rated for Stress Relief
Ingredient fit66
5-HTP and vitamin B6 provide relevant but conditional support, with partial overall amount recognition and a broader formula focus.
Goal fit
5-HTP and vitamin B6 provide the relevant connection, while additional actives and wider goals reduce concentration on stress.
Dose adequacy
5-HTP receives full amount recognition; 20 mg B6 per serving receives partial recognition.
Pathways54
Mood and neurotransmitter-related processes are the strongest connection, with weaker sleep-associated coverage.
Depth
Mood and neurotransmitter-related processes provide the strongest included connection.
Breadth
Only mood and neurotransmitter-related coverage reaches the breadth requirement; sleep-associated coverage remains weaker.
Evidence70
Vitamin B6 leads the evidence finding, though independent stress benefit remains limited. Both declared preparations receive recognition.
Evidence strength
Vitamin B6 leads the evidence finding, but stress results often involve combinations and do not isolate its independent benefit.
Studied preparation
Both declared ingredient preparations receive recognition.
Formulation logic90
Both included ingredients meet the amount requirement, but vitamin B6 lacks recognized partner coverage. No assessed conflict was found.
Partner coverage
Vitamin B6 lacks the partner coverage recognized by the saved findings.
Conflicts
No assessed ingredient conflict was found in the supplied formulation.
Effective doses
Both 5-HTP and vitamin B6 meet the amount requirement used for inclusion.
Impact
Moderate effect
5-HTP at 100 mg relates to appetite and feeling full. Small trials suggest reduced food intake, but their higher daily amounts and limited replication make weight-loss expectations at this serving uncertain.
How this product is rated for Weight Loss
Ingredient fit49
5-HTP provides the main connection within a broader formula. The 100 mg serving provides partial support against the saved reference.
Goal fit
5-HTP provides the main connection within a broader formula.
Dose adequacy
The 100 mg serving provides partial support against the saved reference.
Pathways9
Appetite and fullness are the main connection.
Depth
Appetite and fullness are the main connection.
Breadth
No mechanism reaches the saved threshold for broad support across several areas.
Evidence62
5-HTP provides the strongest saved evidence at a meaningful amount. The ingredients at meaningful amounts use preparations accepted in the saved assessment.
Evidence strength
5-HTP provides the strongest saved evidence among the ingredients at meaningful amounts.
Studied preparation
The ingredients at meaningful amounts use preparations accepted in the saved assessment.
Formulation logic100
The 1 assessed ingredient meets the saved minimum amount, and no conflicts were identified.
Partner coverage
The assessed ingredients can contribute independently or have their required partner.
Conflicts
No ingredient conflicts were identified in the saved checks.
Effective doses
All 1 assessed ingredient meets the saved minimum amount.
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin B6 (Pyridoxine Hydrochloride) | 20 mg | |
Calcium (Dicalcium Phosphate) | 70 mg | |
Phosphorus (Dicalcium Phosphate) | 54 mg | |
5-HTP (Griffonia simplicifolia Seed Extract) | 100 mg |
5-HTP (Griffonia simplicifolia Seed Extract) · 100 mg OverallScore85
Each serving provides 100 mg of 5-HTP from Griffonia simplicifolia. The recorded warning mentions antidepressants or other serotonin-affecting medications.
How this ingredient is rated
Active Ingredient Quality & Bioavailability70
Griffonia simplicifolia is identified as the source, but the saved information does not specify a 5-HTP standardization percentage.
Botanical Source & Standardization
Griffonia simplicifolia is named; a percentage specifying 5-HTP standardization is not recorded.
Dose, Safety & Label Transparency100
The serving provides 100 mg of 5-HTP. The recorded warning mentions antidepressants or other serotonin-affecting medications.
Dosage Potency & Range
The serving contains 100 mg of 5-HTP.
Safety Warnings & Label Clarity
The recorded warning mentions antidepressants or other serotonin-affecting medications.
Value85
The whole-product serving costs about $0.25; its cost relative to the 5-HTP provided is relatively low in the evaluation.
Price per 100mg 5-HTP
The whole-product price corresponds to about $0.25 per 100 mg of 5-HTP.
Alternative products
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
- The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial.
- Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.
- Tryptophan and 5-hydroxytryptophan for depression.
- 5-Hydroxytryptophan (5-HTP) and a MAOI (nialamide) in the treatment of depressions. A double-blind controlled study.
- High Dose Vitamin B6 Reduces Depression Symptoms.
- Can Vitamin B6 Help to Prevent Postpartum Depression? A Randomized Controlled Trial.
- Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
- Associations of dietary B vitamins intakes with depression in adults.
- Impact of vitamin B6 status on psychological distress in a longitudinal study of HIV-1 infection.
- The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial.
- Efficacy of vitamins B1 and B6 as an adjunctive therapy to lithium in bipolar-I disorder: A double-blind, randomized, placebo-controlled, clinical trial.
- Therapeutic effects of magnesium and vitamin B6 in alleviating the symptoms of restless legs syndrome: a randomized controlled clinical trial.
- Effects of poly-gamma-glutamic acid and vitamin B6 supplements on sleep status: a randomized intervention study.
- Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep.
- The effect of pyridoxine administration on melatonin secretion in normal men.
- Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.
- Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
- Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
- Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.